NO20004485D0 - Sykloalkenderivater, deres fremstilling og anvendelse - Google Patents

Sykloalkenderivater, deres fremstilling og anvendelse

Info

Publication number
NO20004485D0
NO20004485D0 NO20004485A NO20004485A NO20004485D0 NO 20004485 D0 NO20004485 D0 NO 20004485D0 NO 20004485 A NO20004485 A NO 20004485A NO 20004485 A NO20004485 A NO 20004485A NO 20004485 D0 NO20004485 D0 NO 20004485D0
Authority
NO
Norway
Prior art keywords
substituents
hydrocarbon group
group optionally
aliphatic hydrocarbon
hydrogen atom
Prior art date
Application number
NO20004485A
Other languages
English (en)
Other versions
NO20004485L (no
NO326426B1 (no
Inventor
Yuzo Ichimori
Masayuki Ii
Katsumi Itoh
Tomoyuki Kitazaki
Junji Yamada
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO20004485L publication Critical patent/NO20004485L/no
Publication of NO20004485D0 publication Critical patent/NO20004485D0/no
Publication of NO326426B1 publication Critical patent/NO326426B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/14Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/061,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/18Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Silicon Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO20004485A 1998-03-09 2000-09-08 Sykloalkenderivater, deres fremstilling og anvendelse NO326426B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5649298 1998-03-09
JP28436298 1998-10-06
PCT/JP1999/001103 WO1999046242A1 (en) 1998-03-09 1999-03-08 Cycloalkene derivatives, process for producing the same, and use

Publications (3)

Publication Number Publication Date
NO20004485L NO20004485L (no) 2000-09-08
NO20004485D0 true NO20004485D0 (no) 2000-09-08
NO326426B1 NO326426B1 (no) 2008-12-01

Family

ID=26397446

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004485A NO326426B1 (no) 1998-03-09 2000-09-08 Sykloalkenderivater, deres fremstilling og anvendelse

Country Status (19)

Country Link
US (1) US6495604B1 (no)
EP (2) EP1524263A1 (no)
JP (2) JP3665712B2 (no)
KR (4) KR20050071719A (no)
CN (1) CN100432049C (no)
AT (1) ATE287393T1 (no)
AU (1) AU747521B2 (no)
BR (1) BR9908610A (no)
CA (1) CA2320467C (no)
DE (1) DE69923300T2 (no)
DK (1) DK1063228T5 (no)
ES (1) ES2232114T3 (no)
HU (1) HU230061B1 (no)
ID (1) ID25649A (no)
NO (1) NO326426B1 (no)
NZ (1) NZ505874A (no)
PT (1) PT1063228E (no)
RU (1) RU2214398C2 (no)
WO (1) WO1999046242A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2214398C2 (ru) 1998-03-09 2003-10-20 Такеда Кемикал Индастриз, Лтд. Производное циклоалкена, способ его получения (варианты), фармацевтическая композиция, способ ингибирования, способ профилактики или лечения
US20040220103A1 (en) * 1999-04-19 2004-11-04 Immunex Corporation Soluble tumor necrosis factor receptor treatment of medical disorders
DE60045033D1 (de) 1999-08-06 2010-11-11 Takeda Pharmaceutical Substituierte aromatische ringverbindungen, verfahren zu ihrer herstellung und ihre anwendung
WO2001040498A1 (en) * 1999-11-29 2001-06-07 Takeda Chemical Industries, Ltd. Process for the production of optically active cyclohexene derivatives and intermediates therefor
JP4863553B2 (ja) * 2000-02-04 2012-01-25 武田薬品工業株式会社 安定な乳化組成物
KR100784752B1 (ko) * 2000-02-04 2007-12-13 다케다 야쿠힌 고교 가부시키가이샤 안정한 에멀젼 조성물
JP4922507B2 (ja) * 2000-08-10 2012-04-25 武田薬品工業株式会社 医薬組成物
EP1310248A4 (en) * 2000-08-10 2008-05-21 Takeda Pharmaceutical PHARMACEUTICAL COMPOSITION
AU2001295949A1 (en) 2000-10-18 2002-04-29 Takeda Chemical Industries Ltd. Process for preparation of optically active sulfonamides and intermediates for their synthesis
EP1348443A4 (en) * 2000-12-08 2005-07-06 Takeda Pharmaceutical COMBINED MEDICINES
US7579325B2 (en) 2001-03-21 2009-08-25 Eisai R & D Management Co., Ltd. Drugs containing reduced of vitamin B2
CA2456029C (en) * 2001-08-03 2010-12-07 Takeda Chemical Industries, Ltd. Stable emulsion composition
US20060058288A1 (en) * 2002-04-08 2006-03-16 Masayuki Ii Severe sepsis preventive therapeutic agent
ATE501128T1 (de) * 2003-12-03 2011-03-15 Boehringer Ingelheim Pharma 1,2,3-triazolamidderivate als inhibitoren der cytokinproduktion
MY147790A (en) * 2005-04-28 2013-01-31 Takeda Pharmaceutical Stable emulsion composition
KR101327610B1 (ko) * 2005-09-14 2013-11-12 다이이찌 산쿄 가부시키가이샤 치환 시클로알켄 유도체
EP1997902B1 (en) 2006-03-30 2013-09-18 Hiroshima University Screening method
US20090062355A1 (en) * 2006-04-20 2009-03-05 Takeda Pharmaceutical Company Limited Pharmaceutical Product
WO2007132825A1 (ja) 2006-05-15 2007-11-22 Takeda Pharmaceutical Company Limited 医薬
JPWO2008004673A1 (ja) 2006-07-07 2009-12-10 武田薬品工業株式会社 シクロアルケン誘導体、その製造法および用途
JP2008260760A (ja) * 2007-03-12 2008-10-30 Daiichi Sankyo Co Ltd 置換シクロアルケン誘導体を含有する医薬組成物
TWI481401B (zh) 2010-01-27 2015-04-21 Takeda Pharmaceutical 藥劑
JP5778161B2 (ja) 2010-09-24 2015-09-16 第一三共株式会社 置換シクロアルケン誘導体の結晶
AU2013286876B2 (en) * 2012-07-03 2017-04-20 Jay Pravda Methods for treating, diagnosing and/or monitoring progression of oxo associated states
US9364438B2 (en) 2012-09-26 2016-06-14 Takeda Pharmaceutical Company Limited Process for producing solid particles
CN107835800B (zh) 2015-05-08 2019-11-26 武田药品工业株式会社 环状化合物
WO2018047888A1 (ja) 2016-09-09 2018-03-15 武田薬品工業株式会社 環状化合物
WO2018156297A1 (en) * 2017-02-24 2018-08-30 Taiwanj Pharmaceuticals Co., Ltd Sulfonamide or amide compounds, compositions and methods for the prophylaxis and/or treatment of autoimmune, inflammation or infection related disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU665931B2 (en) 1990-11-06 1996-01-25 Nippon Shinyaku Co. Ltd. Lyophilized preparation and production thereof
AU653279B2 (en) * 1991-12-30 1994-09-22 Sanofi Novel 2-saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof
US5576016A (en) 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
FI963297L (fi) 1994-02-25 1996-10-18 Takeda Chemical Industries Ltd Antifungaalisia triatsolijohdannaisia sisältävät emulsiot
JPH08109165A (ja) * 1994-08-18 1996-04-30 Chugai Pharmaceut Co Ltd 一酸化窒素合成酵素阻害作用を有するアミノ酸誘導体
AU3230895A (en) * 1994-08-18 1996-03-14 Chugai Seiyaku Kabushiki Kaisha Amino acid derivative having nitrogen monoxide synthetase inhibitor activity
RU2214398C2 (ru) 1998-03-09 2003-10-20 Такеда Кемикал Индастриз, Лтд. Производное циклоалкена, способ его получения (варианты), фармацевтическая композиция, способ ингибирования, способ профилактики или лечения
KR100784752B1 (ko) 2000-02-04 2007-12-13 다케다 야쿠힌 고교 가부시키가이샤 안정한 에멀젼 조성물

Also Published As

Publication number Publication date
CN1291184A (zh) 2001-04-11
JP4342453B2 (ja) 2009-10-14
KR100577044B1 (ko) 2006-05-08
HU230061B1 (hu) 2015-06-29
WO1999046242A1 (en) 1999-09-16
EP1063228B1 (en) 2005-01-19
KR20050071719A (ko) 2005-07-07
DE69923300D1 (de) 2005-02-24
HK1031723A1 (en) 2001-06-22
EP1063228A4 (en) 2001-08-08
AU747521C (en) 1999-09-27
PT1063228E (pt) 2005-05-31
KR20010034555A (ko) 2001-04-25
NO20004485L (no) 2000-09-08
RU2214398C2 (ru) 2003-10-20
EP1063228A1 (en) 2000-12-27
KR100779889B1 (ko) 2007-11-28
NZ505874A (en) 2003-09-26
NO326426B1 (no) 2008-12-01
DK1063228T5 (da) 2009-06-15
AU2746499A (en) 1999-09-27
KR100492098B1 (ko) 2005-06-01
CA2320467A1 (en) 1999-09-16
US6495604B1 (en) 2002-12-17
JP2000178246A (ja) 2000-06-27
AU747521B2 (en) 2002-05-16
CA2320467C (en) 2010-05-04
DK1063228T3 (da) 2005-04-25
HUP0101192A3 (en) 2003-09-29
JP3665712B2 (ja) 2005-06-29
KR20050026075A (ko) 2005-03-14
KR20060017921A (ko) 2006-02-27
CN100432049C (zh) 2008-11-12
ES2232114T3 (es) 2005-05-16
HUP0101192A2 (hu) 2001-08-28
JP2005232168A (ja) 2005-09-02
EP1524263A1 (en) 2005-04-20
ATE287393T1 (de) 2005-02-15
DE69923300T2 (de) 2006-01-05
PL342826A1 (en) 2001-07-02
ID25649A (id) 2000-10-19
BR9908610A (pt) 2000-12-05

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Legal Events

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