NO20023525L - Gonadotropin-frigjörende hormonreseptor-antagonister og metoder i forbindelse med disse - Google Patents

Gonadotropin-frigjörende hormonreseptor-antagonister og metoder i forbindelse med disse

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Publication number
NO20023525L
NO20023525L NO20023525A NO20023525A NO20023525L NO 20023525 L NO20023525 L NO 20023525L NO 20023525 A NO20023525 A NO 20023525A NO 20023525 A NO20023525 A NO 20023525A NO 20023525 L NO20023525 L NO 20023525L
Authority
NO
Norway
Prior art keywords
receptor antagonists
gonadotropin
releasing hormone
hormone receptor
associated methods
Prior art date
Application number
NO20023525A
Other languages
English (en)
Norwegian (no)
Other versions
NO20023525D0 (no
Inventor
Yun-Fei Zhu
Chen Chen
Fabio C Tucci
Zhiqiang Guo
Timothy D Gross
Martin Rowbottom
R Scott Struthers
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Publication of NO20023525D0 publication Critical patent/NO20023525D0/no
Publication of NO20023525L publication Critical patent/NO20023525L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
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    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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NO20023525A 2000-01-25 2002-07-24 Gonadotropin-frigjörende hormonreseptor-antagonister og metoder i forbindelse med disse NO20023525L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17793300P 2000-01-25 2000-01-25
US23968300P 2000-10-11 2000-10-11
PCT/US2001/002740 WO2001055119A2 (en) 2000-01-25 2001-01-25 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

Publications (2)

Publication Number Publication Date
NO20023525D0 NO20023525D0 (no) 2002-07-24
NO20023525L true NO20023525L (no) 2002-07-24

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KR100814269B1 (ko) 2008-03-18
MXPA02006848A (es) 2002-12-13
US7179815B2 (en) 2007-02-20
WO2001055119A2 (en) 2001-08-02
US20050234082A1 (en) 2005-10-20
US20020132820A1 (en) 2002-09-19
NO20023525D0 (no) 2002-07-24
US20070208049A1 (en) 2007-09-06
KR20030012846A (ko) 2003-02-12
US6872728B2 (en) 2005-03-29
EP1255738B1 (de) 2012-03-07
AU3797501A (en) 2001-08-07
DK1255738T3 (da) 2012-06-25
PT1255738E (pt) 2012-06-19
EP1255738A2 (de) 2002-11-13
JP2003520856A (ja) 2003-07-08
WO2001055119A3 (en) 2002-02-14
JP4931314B2 (ja) 2012-05-16
ES2383954T3 (es) 2012-06-27
HK1051042A1 (en) 2003-07-18
US7462625B2 (en) 2008-12-09
CA2398018C (en) 2011-10-18
CY1112815T1 (el) 2016-02-10
US6608197B2 (en) 2003-08-19
CA2398018A1 (en) 2001-08-02
AU767585B2 (en) 2003-11-20
ATE548357T1 (de) 2012-03-15

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