NO20051617L - Piperidinderivater av heterocyklusfusjonerte benzodioksaner med antidepressiv aktivitet - Google Patents

Piperidinderivater av heterocyklusfusjonerte benzodioksaner med antidepressiv aktivitet

Info

Publication number: NO20051617L
Authority: NO; Norway
Prior art keywords: disorder; depression; benzodioxanes; heterocycle; fused
Prior art date: 2002-09-12

Application number

NO20051617A

Other languages

English (en)

Norwegian (no)

Other versions

NO20051617D0 (no

Inventor

Gary Paul Stack

Magda Asselin

Deborah Ann Evrard

Michael Byron Webb

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-12

Filing date

2005-03-31

Publication date

2005-03-31

2005-03-31 Application filed by Wyeth Corp filed Critical Wyeth Corp

2005-03-31 Publication of NO20051617D0 publication Critical patent/NO20051617D0/no

2005-03-31 Publication of NO20051617L publication Critical patent/NO20051617L/no

Links

230000001430 anti-depressive effect Effects 0.000 title 1
239000000935 antidepressant agent Substances 0.000 title 1
229940005513 antidepressants Drugs 0.000 title 1
BNBQRQQYDMDJAH-UHFFFAOYSA-N benzodioxan Chemical class C1=CC=C2OCCOC2=C1 BNBQRQQYDMDJAH-UHFFFAOYSA-N 0.000 title 1
230000000694 effects Effects 0.000 title 1
150000003053 piperidines Chemical class 0.000 title 1
ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 abstract 2
208000007848 Alcoholism Diseases 0.000 abstract 1
206010002650 Anorexia nervosa and bulimia Diseases 0.000 abstract 1
208000019901 Anxiety disease Diseases 0.000 abstract 1
208000022497 Cocaine-Related disease Diseases 0.000 abstract 1
208000020401 Depressive disease Diseases 0.000 abstract 1
208000030814 Eating disease Diseases 0.000 abstract 1
208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
208000011688 Generalised anxiety disease Diseases 0.000 abstract 1
208000008589 Obesity Diseases 0.000 abstract 1
208000021384 Obsessive-Compulsive disease Diseases 0.000 abstract 1
206010036618 Premenstrual syndrome Diseases 0.000 abstract 1
201000001880 Sexual dysfunction Diseases 0.000 abstract 1
206010041250 Social phobia Diseases 0.000 abstract 1
201000007930 alcohol dependence Diseases 0.000 abstract 1
230000036506 anxiety Effects 0.000 abstract 1
229960003920 cocaine Drugs 0.000 abstract 1
201000006145 cocaine dependence Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
235000014632 disordered eating Nutrition 0.000 abstract 1
206010013663 drug dependence Diseases 0.000 abstract 1
230000001544 dysphoric effect Effects 0.000 abstract 1
208000024732 dysthymic disease Diseases 0.000 abstract 1
238000011010 flushing procedure Methods 0.000 abstract 1
208000029364 generalized anxiety disease Diseases 0.000 abstract 1
208000013403 hyperactivity Diseases 0.000 abstract 1
235000020824 obesity Nutrition 0.000 abstract 1
208000019906 panic disease Diseases 0.000 abstract 1
208000028173 post-traumatic stress disease Diseases 0.000 abstract 1
231100000872 sexual dysfunction Toxicity 0.000 abstract 1
230000001457 vasomotor Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Addiction (AREA)
Hematology (AREA)
Gynecology & Obstetrics (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20051617A 2002-09-12 2005-03-31 Piperidinderivater av heterocyklusfusjonerte benzodioksaner med antidepressiv aktivitet NO20051617L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US41003302P	2002-09-12	2002-09-12
US10/659,160 US6939877B2 (en)	2002-09-12	2003-09-10	Antidepressant piperidine derivatives of heterocycle-fused benzodioxans
PCT/US2003/028523 WO2004024733A1 (en)	2002-09-12	2003-09-11	Antidepressant piperidine derivatives of heterocycle-fused benzodioxans

Publications (2)

Publication Number	Publication Date
NO20051617D0 NO20051617D0 (no)	2005-03-31
NO20051617L true NO20051617L (no)	2005-03-31

Family

ID=31994047

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20051617A NO20051617L (no)	2002-09-12	2005-03-31	Piperidinderivater av heterocyklusfusjonerte benzodioksaner med antidepressiv aktivitet

Country Status (13)

Country	Link
US (3)	US6939877B2 (pt)
EP (1)	EP1537120A1 (pt)
JP (1)	JP2006510594A (pt)
KR (1)	KR20050042192A (pt)
CN (2)	CN100351256C (pt)
AU (1)	AU2003270559A1 (pt)
BR (1)	BR0314431A (pt)
EC (1)	ECSP055657A (pt)
MX (1)	MXPA05002830A (pt)
NO (1)	NO20051617L (pt)
RU (1)	RU2005107588A (pt)
WO (1)	WO2004024733A1 (pt)
ZA (1)	ZA200502042B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6939877B2 (en) *	2002-09-12	2005-09-06	Wyeth	Antidepressant piperidine derivatives of heterocycle-fused benzodioxans
EP1856126A2 (en) *	2005-02-17	2007-11-21	Wyeth a Corporation of the State of Delaware	Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
AR060493A1 (es) *	2006-04-18	2008-06-18	Wyeth Corp	Derivados de benzodioxano y benzodioxolano. procesos de obtencion.
CN101563342B (zh) *	2006-12-21	2012-09-05	伊莱利利公司	用于治疗癌症的咪唑啉酮基氨基嘧啶化合物
TW200904446A (en) *	2007-05-30	2009-02-01	Wyeth Corp	Antidepressant heteroaryl derivatives of heterocycle-fused benzodioxans
US8399432B2 (en) *	2009-10-27	2013-03-19	Lipogen Ltd.	Compositions and methods of treatment for alleviating premenstrual syndrome symptoms
WO2012114347A1 (en) *	2011-02-21	2012-08-30	Avra Laboratories Pvt. Ltd.	Synthesis of chiral substituted benzenes and related aromatic compounds containing 1,2 diols protected as diacetal groups

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2266677A (en) *		1941-12-16		Garden implement
US1706658A (en) *	1927-04-15	1929-03-26	Winthrop S Davis	Hoe
US3293674A (en) *	1965-04-02	1966-12-27	Sapia James	Combination sickle and weed pulling tool
GB1354554A (en)	1970-08-31	1974-06-05	Robins Co Inc A H	2-substituted benzimidazoles
US4695575A (en) *	1984-11-13	1987-09-22	Janssen Pharmaceutica, N.V.	4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
PH23995A (en)	1984-01-09	1990-02-09	Janssen Pharmaceutica Nv	4((bicycle heterocyclyl)-methyl and hetero)piperidines
US5364866A (en)	1989-05-19	1994-11-15	Hoechst-Roussel Pharmaceuticals, Inc.	Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
WO1991013872A1 (en)	1990-03-15	1991-09-19	The Upjohn Company	Therapeutically useful heterocyclic indole compounds
KR930702000A (ko) *	1990-11-24	1993-09-08	데이빗 로버츠	노년기 치매, 식용항진, 편두통, 또는 식용불량의 치료를 위한 파로세틴의 사용
DE69330283T2 (de)	1992-07-13	2002-01-10	Janssen Pharmaceutica N.V., Beerse	Neue 4-(3-benzofuranyl) piperidinyl und 4-(3-benzothienyl) piperidinyl-derivate und diese enthaltende pharmazeutische zusammenstellungen
US5276042A (en) *	1993-04-16	1994-01-04	Crenshaw Roger T	Treatment of premature ejaculation
GB9318431D0 (en) *	1993-09-06	1993-10-20	Boots Co Plc	Therapeutic agents
GB9402029D0 (en) *	1994-02-03	1994-03-30	Smithkline Beecham Plc	Novel formulation
US5756532A (en) *	1995-11-06	1998-05-26	American Home Products Corporation	Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
DE19602355A1 (de) *	1996-01-24	1997-07-31	Hoechst Ag	Mehrfach fucosylierte Dicarbonsäuren mit antiadhäsiven Eigenschaften
US5869490A (en) *	1996-10-15	1999-02-09	American Home Products Corporation	Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one
DE69722020T2 (de)	1996-10-15	2004-01-22	Wyeth	Azaheterocyclylmethyl-derivate von 2,3,8,9-tetrahydro-7h-1,4-dioxino[2,3-e]indol-8-on
GB9627005D0 (en) *	1996-12-27	1997-02-12	Knoll Ag	Therapeutic agents
GB9704948D0 (en) *	1997-03-11	1997-04-30	Knoll Ag	Therapeutic agents
TWI242011B (en) *	1997-03-31	2005-10-21	Eisai Co Ltd	1,4-substituted cyclic amine derivatives
US6720003B2 (en) *	2001-02-16	2004-04-13	Andrx Corporation	Serotonin reuptake inhibitor formulations
US6458802B1 (en) *	2001-03-14	2002-10-01	Wyeth	Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline
US6593350B2 (en) *	2001-04-26	2003-07-15	Wyeth	Antidepressant indoletetrahydropyridine derivatives of 2,3-dihydro-7H-[1,4]dioxino[2,3-e]indole
US6939877B2 (en) *	2002-09-12	2005-09-06	Wyeth	Antidepressant piperidine derivatives of heterocycle-fused benzodioxans

2003
- 2003-09-10 US US10/659,160 patent/US6939877B2/en not_active Expired - Fee Related
- 2003-09-11 JP JP2004536506A patent/JP2006510594A/ja active Pending
- 2003-09-11 WO PCT/US2003/028523 patent/WO2004024733A1/en not_active Ceased
- 2003-09-11 KR KR1020057004124A patent/KR20050042192A/ko not_active Withdrawn
- 2003-09-11 RU RU2005107588/04A patent/RU2005107588A/ru not_active Application Discontinuation
- 2003-09-11 AU AU2003270559A patent/AU2003270559A1/en not_active Abandoned
- 2003-09-11 BR BR0314431-3A patent/BR0314431A/pt not_active IP Right Cessation
- 2003-09-11 MX MXPA05002830A patent/MXPA05002830A/es active IP Right Grant
- 2003-09-11 EP EP03752260A patent/EP1537120A1/en not_active Withdrawn
- 2003-09-11 CN CNB038214687A patent/CN100351256C/zh not_active Expired - Fee Related
- 2003-09-11 CN CNA2007101523868A patent/CN101230066A/zh active Pending
2005
- 2005-03-10 EC EC2005005657A patent/ECSP055657A/es unknown
- 2005-03-10 ZA ZA200502042A patent/ZA200502042B/en unknown
- 2005-03-31 NO NO20051617A patent/NO20051617L/no not_active Application Discontinuation
- 2005-06-01 US US11/142,787 patent/US7479500B2/en not_active Expired - Fee Related
2008
- 2008-10-20 US US12/254,118 patent/US20090042895A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20050228009A1 (en)	2005-10-13
NO20051617D0 (no)	2005-03-31
US6939877B2 (en)	2005-09-06
US20040147523A1 (en)	2004-07-29
AU2003270559A1 (en)	2004-04-30
RU2005107588A (ru)	2006-01-20
JP2006510594A (ja)	2006-03-30
EP1537120A1 (en)	2005-06-08
BR0314431A (pt)	2005-09-27
CN100351256C (zh)	2007-11-28
CN1681820A (zh)	2005-10-12
MXPA05002830A (es)	2005-08-16
WO2004024733A1 (en)	2004-03-25
ZA200502042B (en)	2006-08-30
ECSP055657A (es)	2005-07-06
KR20050042192A (ko)	2005-05-04
CN101230066A (zh)	2008-07-30
US7479500B2 (en)	2009-01-20
US20090042895A1 (en)	2009-02-12

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Legal Events

Date	Code	Title	Description
2010-11-29	FC2A	Withdrawal, rejection or dismissal of laid open patent application