NO20061479L - Anvendelse av modifiserte cyklosporiner for behandling av HCV-forstyrrelser - Google Patents

Anvendelse av modifiserte cyklosporiner for behandling av HCV-forstyrrelser

Info

Publication number
NO20061479L
NO20061479L NO20061479A NO20061479A NO20061479L NO 20061479 L NO20061479 L NO 20061479L NO 20061479 A NO20061479 A NO 20061479A NO 20061479 A NO20061479 A NO 20061479A NO 20061479 L NO20061479 L NO 20061479L
Authority
NO
Norway
Prior art keywords
treatment
cyclosporins
hcv
disorders
modified
Prior art date
Application number
NO20061479A
Other languages
English (en)
Norwegian (no)
Inventor
Makoto Hijikata
Kunitada Shimotohno
Koichi Watashi
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20061479L publication Critical patent/NO20061479L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO20061479A 2003-09-03 2006-03-31 Anvendelse av modifiserte cyklosporiner for behandling av HCV-forstyrrelser NO20061479L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0320638.0A GB0320638D0 (en) 2003-09-03 2003-09-03 Organic compounds
PCT/EP2004/009804 WO2005021028A1 (en) 2003-09-03 2004-09-02 Use of modified cyclosporins for the treatment of hcv disorders

Publications (1)

Publication Number Publication Date
NO20061479L true NO20061479L (no) 2006-06-02

Family

ID=28686843

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061479A NO20061479L (no) 2003-09-03 2006-03-31 Anvendelse av modifiserte cyklosporiner for behandling av HCV-forstyrrelser

Country Status (29)

Country Link
US (1) US7968518B2 (da)
EP (2) EP1797892B1 (da)
JP (1) JP4688806B2 (da)
KR (1) KR101116968B1 (da)
CN (1) CN1842343A (da)
AU (2) AU2004268382A1 (da)
BR (1) BRPI0414062B8 (da)
CA (1) CA2537137C (da)
CY (1) CY1110506T1 (da)
DE (1) DE602004022061D1 (da)
DK (1) DK1663287T3 (da)
ES (1) ES2328361T3 (da)
GB (1) GB0320638D0 (da)
HR (1) HRP20090535T1 (da)
IL (1) IL173909A (da)
IS (1) IS2917B (da)
MA (1) MA28032A1 (da)
MX (1) MXPA06002394A (da)
NO (1) NO20061479L (da)
NZ (1) NZ545495A (da)
PL (1) PL1663287T3 (da)
PT (1) PT1663287E (da)
RU (1) RU2389501C2 (da)
SG (1) SG149063A1 (da)
SI (1) SI1663287T1 (da)
TN (1) TNSN06071A1 (da)
TW (1) TWI342782B (da)
WO (1) WO2005021028A1 (da)
ZA (1) ZA200601550B (da)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE40987E1 (en) 1998-07-01 2009-11-17 Debiopharm S.A. Cyclosporin with improved activity profile
AU2004222306A1 (en) 2003-03-17 2004-09-30 Albany Molecular Research, Inc. Novel cyclosporins
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
GB0500020D0 (en) * 2005-01-04 2005-02-09 Novartis Ag Organic compounds
JP2008506648A (ja) 2004-07-14 2008-03-06 ノバルティス アクチエンゲゼルシャフト Ｃ型肝炎（ｈｃｖ）処置のためのシクロスポリンとペグ化インターフェロンの組合せ剤の使用
WO2006039163A2 (en) 2004-09-29 2006-04-13 Amr Technology, Inc. Cyclosporin alkyne analogues and their pharmaceutical uses
JP2008514702A (ja) 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド 新規シクロスポリン類似体およびそれらの薬学的使用
SI1802650T1 (sl) * 2004-10-01 2012-03-30 Scynexis Inc Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c
PT1793844E (pt) 2004-10-01 2011-03-10 Debiopharm Sa Utilização de [d-meala]3-[etval]4-csa para o tratamento de infecção causada pelo vírus da hepatite c
US7196161B2 (en) 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
WO2006041631A2 (en) 2004-10-06 2006-04-20 Amr Technology, Inc. Novel cyclosporin alkynes and their utility as pharmaceutical agents
ATE412005T1 (de) 2004-11-22 2008-11-15 Astellas Pharma Inc Zyklosporinanalog
US7897565B2 (en) * 2004-12-23 2011-03-01 Novartis Ag Compositions for HCV treatment
RU2007128098A (ru) * 2004-12-23 2009-01-27 Новартис АГ (CH) Соединения для лечения инфекций, вызываемых вирусами семейства flaviviridae
RU2427372C2 (ru) * 2005-06-17 2011-08-27 Новартис Аг Применение санглиферина для лечения вируса гепатита с
CN101316606B (zh) * 2005-09-30 2015-05-27 西尼克斯公司 治疗和预防丙型肝炎感染的方法和药物组合物
CA2623864C (en) * 2005-09-30 2014-12-16 Scynexis, Inc. Arylalkyl and heteroarylalkyl derivatives of cyclosporine a for the treatment and prevention of viral infection
CN105169369B (zh) * 2005-09-30 2019-10-18 中美华世通生物医药科技（武汉）有限公司 治疗和预防丙型肝炎感染的方法和药物组合物
PL1957518T3 (pl) * 2005-10-26 2016-07-29 Astellas Pharma Inc Nowe cykliczne związki peptydowe
US7696166B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7696165B2 (en) 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
EP2023918B1 (en) 2006-05-19 2011-03-23 Scynexis, Inc. Cyclosporins for the treatment and prevention of ocular disorders
KR101089112B1 (ko) * 2006-06-02 2011-12-06 피씨 제스띠옹 에스.아.에스. 활성 전자 관리
SG175621A1 (en) * 2006-10-12 2011-11-28 Novartis Ag Use of modified cyclosporins
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
RU2462262C2 (ru) * 2007-01-04 2012-09-27 Дебиофарм С А Неиммуносупрессорный циклоспорин для лечения врожденной миопатии ульриха
KR20100017547A (ko) * 2007-05-02 2010-02-16 아스텔라스세이야쿠 가부시키가이샤 신규 시클릭 펩티드 화합물
US20110158908A1 (en) * 2007-08-24 2011-06-30 Sapporo Medical University Cyclosporin a-binding protein
WO2009148615A1 (en) * 2008-06-06 2009-12-10 Scynexis, Inc. Cyclosporin analogs and their use in the treatment of hcv infections
JP5820722B2 (ja) * 2008-06-06 2015-11-24 スシネキス インク シクロスポリン類似体及びｈｃｖ感染の治療におけるその使用
AU2009276241A1 (en) * 2008-07-30 2010-02-04 Ciclofilin Pharmaceuticals Corp. Nonimmunosuppressive cyclosporine analogue molecules
JP5625910B2 (ja) * 2008-09-24 2014-11-19 アステラス製薬株式会社 ペプチド化合物およびその製造方法
CA2741829A1 (en) * 2008-11-06 2010-05-14 Debio Recherche Pharmaceutique S.A. Cycloundecadepsipeptide compounds and use of said compounds as a medicament
CA2748389A1 (en) * 2008-12-31 2010-07-08 Scynexis, Inc. Derivatives of cyclosporin a
EP2391376A4 (en) 2009-01-30 2012-08-01 Enanta Pharm Inc ANALOGUES OF CYCLOSPORIN FOR PREVENTING OR TREATING HEPATITIS C INFECTION
US8481483B2 (en) 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
WO2011063076A1 (en) 2009-11-19 2011-05-26 Itherx Pharmaceuticals, Inc. Methods of treating hepatitis c virus with oxoacetamide compounds
CN102869367A (zh) 2009-12-09 2013-01-09 西尼克斯公司 新颖的环肽
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
KR20140035305A (ko) 2010-10-05 2014-03-21 노파르티스 아게 C형 간염 바이러스 감염의 새로운 치료법
CN105381450A (zh) 2010-11-30 2016-03-09 诺华有限公司 丙型肝炎病毒感染的新疗法
JO3337B1 (ar) 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
LT2651965T (lt) 2010-12-15 2019-01-10 Contravir Pharmaceuticals, Inc. Ciklosporino analogo molekulės su modifikuotomis 1 ir 3 aminorūgštimis
CN105749246A (zh) 2011-03-31 2016-07-13 诺华股份有限公司 治疗丙肝病毒感染的阿拉泊韦
RS53911B1 (sr) 2011-04-01 2015-08-31 Novartis Ag Tretman u infekciji virusom hepatitis b zasebno ili u kombinaciji sa hepatitis delta virusom i bolesti jetre koje ih prate
KR20140011379A (ko) 2011-04-13 2014-01-28 노파르티스 아게 알리스포리비르를 사용하는 c형 간염 바이러스 감염의 치료
JP2014528947A (ja) 2011-09-27 2014-10-30 ノバルティス アーゲー Ｃ型肝炎ウイルス感染症の治療のためのアリスポリビル
CA2872162A1 (en) 2012-05-07 2013-11-14 Novartis Ag Pharmacokinetic modulation with alisporivir
CA2874548A1 (en) 2012-06-01 2013-12-05 Allergan, Inc. Cyclosporin a analogs
US8906853B2 (en) 2012-11-28 2014-12-09 Enanta Pharmaceuticals, Inc. [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
WO2015008223A1 (en) 2013-07-17 2015-01-22 Novartis Ag Treatment of hepatitis c virus infection with alisporivir and ribavirin
KR20160045136A (ko) 2013-08-26 2016-04-26 이난타 파마슈티칼스, 인코포레이티드 C형 간염을 예방 또는 치료하기 위한 사이클로스포린 유사체
WO2015136455A1 (en) 2014-03-13 2015-09-17 Novartis Ag New treatments of hepatitis c virus infection
WO2016073480A1 (en) 2014-11-03 2016-05-12 Enanta Pharmaceuticals, Inc. Novel cyclosporin analogues for preventing or treating hepatitis c infection
WO2016112321A1 (en) 2015-01-08 2016-07-14 Allergan, Inc. Cyclosporin derivatives wherein the mebmt sidechain has been cyclized
CN116367843A (zh) * 2020-08-24 2023-06-30 纳诺莫里克斯有限公司 病毒抑制剂

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US4917888A (en) 1985-06-26 1990-04-17 Cetus Corporation Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation
US4766106A (en) 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
JP2514950B2 (ja) 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質，その製造法および中間体
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
DE69124459T3 (de) * 1990-11-02 2001-05-31 Novartis Ag, Basel Zyklosporine
US5595732A (en) 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5382657A (en) 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
US6174868B1 (en) * 1992-09-10 2001-01-16 Isis Pharmaceuticals, Inc. Compositions and methods for treatment of hepatitis C virus-associated diseases
WO1994008943A1 (fr) 1992-10-21 1994-04-28 Yoshitomi Pharmaceutical Industries, Ltd. Compose 2-amino-1,3-propanediol et immunosuppresseur
HUT75533A (en) 1993-11-10 1997-05-28 Schering Corp Improved interferon polymer conjugates
ATE211726T1 (de) 1994-08-22 2002-01-15 Welfide Corp Benzolderivate und deren medizinische verwendung
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
JP3786447B2 (ja) * 1995-03-31 2006-06-14 エーザイ株式会社 Ｃ型肝炎の予防・治療剤
US5908621A (en) 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
FR2757521B1 (fr) 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757520B1 (fr) 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent
FR2757522B1 (fr) 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
USRE39072E1 (en) 1997-04-04 2006-04-18 Mitsubishi Pharma Corporation 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same
JPH1180026A (ja) * 1997-09-02 1999-03-23 Yoshitomi Pharmaceut Ind Ltd 新規免疫抑制剤、その使用方法およびその同定方法
GB9811854D0 (en) * 1998-06-02 1998-07-29 Ciba Geigy Ag Organic compounds
USRE40987E1 (en) * 1998-07-01 2009-11-17 Debiopharm S.A. Cyclosporin with improved activity profile
EP1300405B1 (en) 2000-07-13 2007-04-18 Sankyo Company, Limited Amino alcohol derivatives
EP1315735A4 (en) 2000-08-31 2005-04-06 Merck & Co Inc Phosphate derivatives as immunoregulatory compounds
US20040033946A1 (en) * 2000-10-19 2004-02-19 Futoshi Shibasaki Cell damage inhibitor
JP2002125683A (ja) * 2000-10-27 2002-05-08 Tokyoto Igaku Kenkyu Kiko インターフェロンの有効性を予測する方法並びにそれに用いられるプライマー及びプローブ
MXPA03008755A (es) 2001-03-26 2004-02-18 Novartis Ag Derivados de 2-amino-propanol.
JP2002316985A (ja) 2001-04-20 2002-10-31 Sankyo Co Ltd ベンゾチオフェン誘導体
CA2461212C (en) 2001-09-27 2010-08-17 Kyorin Pharmaceutical Co., Ltd. Diaryl sulfide derivatives, salts thereof and immunosuppressive agents using the same
DE60235900D1 (de) 2001-09-27 2010-05-20 Kyorin Seiyaku Kk Osuppressivum
ATE441654T1 (de) 2002-01-18 2009-09-15 Merck & Co Inc Edg-rezeptoragonisten
AU2003202994B2 (en) 2002-01-18 2007-11-22 Merck Sharp & Dohme Corp. N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists
US20030213603A1 (en) 2002-05-14 2003-11-20 Fisher David B. Dual use extension apparatus for a tool
AP2005003213A0 (en) 2002-06-28 2005-03-31 Univ Cagliari 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections.
GB0313444D0 (en) 2003-06-11 2003-07-16 Midland Medical Technologies L Modular dysplasia cup
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
PT1793844E (pt) 2004-10-01 2011-03-10 Debiopharm Sa Utilização de [d-meala]3-[etval]4-csa para o tratamento de infecção causada pelo vírus da hepatite c
US7897565B2 (en) 2004-12-23 2011-03-01 Novartis Ag Compositions for HCV treatment

Also Published As

Publication number Publication date
IS8371A (is) 2006-03-24
AU2008203031A1 (en) 2008-07-31
AU2008203031B2 (en) 2011-04-07
GB0320638D0 (en) 2003-10-01
BRPI0414062B8 (pt) 2021-05-25
HK1091732A1 (en) 2007-01-26
US7968518B2 (en) 2011-06-28
RU2006110533A (ru) 2007-10-10
PL1663287T3 (pl) 2009-12-31
PT1663287E (pt) 2009-09-03
AU2004268382A1 (en) 2005-03-10
TWI342782B (en) 2011-06-01
NZ545495A (en) 2010-01-29
EP1797892A1 (en) 2007-06-20
RU2389501C2 (ru) 2010-05-20
MA28032A1 (fr) 2006-07-03
ZA200601550B (en) 2007-05-30
MXPA06002394A (es) 2006-06-20
BRPI0414062B1 (pt) 2019-06-25
EP1797892B1 (en) 2013-10-23
JP2007504260A (ja) 2007-03-01
KR20060132798A (ko) 2006-12-22
KR101116968B1 (ko) 2012-03-14
CY1110506T1 (el) 2015-04-29
TW200524626A (en) 2005-08-01
HRP20090535T1 (hr) 2009-11-30
SG149063A1 (en) 2009-01-29
CA2537137A1 (en) 2005-03-10
TNSN06071A1 (en) 2007-10-03
WO2005021028A1 (en) 2005-03-10
CA2537137C (en) 2013-05-28
US20070275884A1 (en) 2007-11-29
ES2328361T3 (es) 2009-11-12
EP1663287A1 (en) 2006-06-07
IL173909A0 (en) 2006-07-05
IS2917B (is) 2014-12-15
EP1663287B1 (en) 2009-07-15
IL173909A (en) 2011-03-31
BRPI0414062A (pt) 2006-10-24
DK1663287T3 (da) 2009-11-09
JP4688806B2 (ja) 2011-05-25
CN1842343A (zh) 2006-10-04
SI1663287T1 (sl) 2009-10-31
DE602004022061D1 (de) 2009-08-27

Similar Documents

Publication Publication Date Title
NO20061479L (no) Anvendelse av modifiserte cyklosporiner for behandling av HCV-forstyrrelser
NO20073765L (no) Forbindelser for behandling av flaviviridae
MA30893B1 (fr) Inhibiteurs de la protease ns3 du vhc
EA200800371A1 (ru) Ингибиторы ns3 протеазы вгс
EA200702493A1 (ru) Соединения и способы лечения или предотвращения флавивирусных инфекций
EA200901241A1 (ru) Соединения для лечения гепатита с
NZ594755A (en) Cyclosporin analogues for preventing or treating hepatitis c infection
NO20083694L (no) Bruk av rylener som markorer for vaesker
NO20081086L (no) Makrosykliske peptider som HCV NS3-proteaseinhibitorer
WO2006119061A3 (en) Hcv ns3 protease inhibitors
IL182315A0 (en) 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis c infection
NO20076502L (no) Pyrrolopyridiner nyttige som inhibitorer av proteinkinase
CA2473070A1 (en) Proline compounds as ns3-serine protease inhibitors for use in treatment of hepatites c virus infection
ECSP045191A (es) "nuevos péptidos como inhibidores de la proteasa serina ns3 del virus de la hepatitis c"
MXPA05012323A (es) Sulfonamidas ciclicas para la inhibicion de gama-secretasa.
EA201000329A1 (ru) Циклические депсипептиды
EA201070423A1 (ru) Диарильные соединения оксадиазолов
NO20055649L (no) Substituert dihydrokinazolin med antiviale egenskaper
NO20076515L (no) Hydantoinforbindelser
NO20075815L (no) Formuleringer og metoder for behandling av amyloidose
WO2005074598A3 (en) Nitroxyl progenitor compounds and methods of use
DK1373220T3 (da) Benzimidazoler, som er nyttige ved behandling af seksuel dysfunktion
GT200600262A (es) Uso de la sangliferina en el hcv (virus de la hepatitis "c")
DE60317935D1 (de) Alpha-aminoamid-derivate als mittel gegen migräne
WO2004099165A3 (en) Heterocyclic compounds and hydro isomers thereof

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application