NO20063917L - Fremgangsmate for syntese av N-[3-(3-cyanopyrazol[1,5A]pyrimidin-7-yl)-fenyl]-N-etyl-acetamid - Google Patents

Fremgangsmate for syntese av N-[3-(3-cyanopyrazol[1,5A]pyrimidin-7-yl)-fenyl]-N-etyl-acetamid

Info

Publication number: NO20063917L
Authority: NO; Norway
Prior art keywords: formula; phenyl; ethyl; acetamide; synthesis
Prior art date: 2004-02-02

Application number

NO20063917A

Other languages

English (en)

Norwegian (no)

Inventor

Katalin Szoke

Laszlo Czibula

Laszlo Dobay

Eva Werkne Papp

Judit Nagyne Bagdy

Gabor Tarkanyi

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-02

Filing date

2006-09-01

Publication date

2006-11-01

2006-09-01 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

2006-11-01 Publication of NO20063917L publication Critical patent/NO20063917L/no

Links

230000015572 biosynthetic process Effects 0.000 title abstract 4
238000003786 synthesis reaction Methods 0.000 title abstract 4
YMJLEPMVGQBLHL-UHFFFAOYSA-N 1h-pyrazole-5-carbonitrile Chemical compound N#CC1=CC=NN1 YMJLEPMVGQBLHL-UHFFFAOYSA-N 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 3
239000012535 impurity Substances 0.000 abstract 3
FZSDJRKAWHMQFF-UHFFFAOYSA-N n-[3-[3-(dimethylamino)prop-2-enoyl]phenyl]-n-ethylacetamide;hydrochloride Chemical compound Cl.CCN(C(C)=O)C1=CC=CC(C(=O)C=CN(C)C)=C1 FZSDJRKAWHMQFF-UHFFFAOYSA-N 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
FFNKBQRKZRMYCL-UHFFFAOYSA-N 5-amino-1h-pyrazole-4-carbonitrile Chemical compound NC1=NNC=C1C#N FFNKBQRKZRMYCL-UHFFFAOYSA-N 0.000 abstract 1
-1 pyrimidine-1-yl Chemical group 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Anesthesiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20063917A 2004-02-02 2006-09-01 Fremgangsmate for syntese av N-[3-(3-cyanopyrazol[1,5A]pyrimidin-7-yl)-fenyl]-N-etyl-acetamid NO20063917L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU0400325A HUP0400325A3 (en)	2004-02-02	2004-02-02	Pure n-[3-(-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-n-ethyl-acetamide, process for its preparation and intermediates
PCT/HU2005/000008 WO2005073235A2 (fr)	2004-02-02	2005-01-31	Procede de synthese de n- [3-(3-cyanopyrazolo [1,5a] pyrimidin-7-yl)-phenyl]-n-ethyl-acetamide

Publications (1)

Publication Number	Publication Date
NO20063917L true NO20063917L (no)	2006-11-01

Family

ID=89981959

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20063917A NO20063917L (no)	2004-02-02	2006-09-01	Fremgangsmate for syntese av N-[3-(3-cyanopyrazol[1,5A]pyrimidin-7-yl)-fenyl]-N-etyl-acetamid

Country Status (9)

Country	Link
EP (2)	EP1711501B1 (fr)
JP (1)	JP2007519700A (fr)
AT (2)	ATE438647T1 (fr)
DE (2)	DE602005015902D1 (fr)
EA (1)	EA010830B1 (fr)
HU (1)	HUP0400325A3 (fr)
NO (1)	NO20063917L (fr)
RS (1)	RS20060427A (fr)
WO (1)	WO2005073235A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005099712A2 (fr) *	2004-04-19	2005-10-27	Sanmar Speciality Chemicals Limited	Procede de preparation de n-[3-(3-cyanopyrazolo [1,5-a]pyrimidin-7-yl)phenyl]-n-ethylacetamide
WO2006070244A2 (fr) *	2004-11-22	2006-07-06	Bakulesh Mafatlal Khamar	Processus de preparation de zaleplon

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4626538A (en)	1983-06-23	1986-12-02	American Cyanamid Company	[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines
US5714607A (en) *	1995-12-01	1998-02-03	American Cyanamid Company	Process improvement in the synthesis of N- 3-(3-cyano-pyrazolo 1,5-a!pyrimidin-7-yl)phenyl!-N-ethylacetamide
ES2223311T1 (es) *	2001-06-12	2005-03-01	Biogal Gyogyszergyar Rt.	Procedimiento para la preparacion de n-(3-(3-cianopirazol(1,5-a)pirimidin-7-il)fenil)-n-etilacetamida (zaleplon).
PL374176A1 (en) *	2001-08-01	2005-10-03	Biogal Gyogyszergyar Rt	Process for purifying n-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-n-ethylacetamide(zaleplon) and crystalline forms of zaleplon accessible with the process
PL207322B1 (pl) *	2002-05-14	2010-11-30	Adamed Społka Z Ograniczoną Odpowiedzialnością	Sposób wytwarzania zaleplonu

2004
- 2004-02-02 HU HU0400325A patent/HUP0400325A3/hu unknown
2005
- 2005-01-31 AT AT08008434T patent/ATE438647T1/de not_active IP Right Cessation
- 2005-01-31 EP EP05708499A patent/EP1711501B1/fr not_active Expired - Lifetime
- 2005-01-31 RS RSP-2006/0427A patent/RS20060427A/sr unknown
- 2005-01-31 DE DE602005015902T patent/DE602005015902D1/de not_active Expired - Fee Related
- 2005-01-31 EA EA200601417A patent/EA010830B1/ru not_active IP Right Cessation
- 2005-01-31 WO PCT/HU2005/000008 patent/WO2005073235A2/fr not_active Ceased
- 2005-01-31 AT AT05708499T patent/ATE420882T1/de not_active IP Right Cessation
- 2005-01-31 EP EP08008434A patent/EP1950213B1/fr not_active Expired - Lifetime
- 2005-01-31 DE DE602005012365T patent/DE602005012365D1/de not_active Expired - Fee Related
- 2005-01-31 JP JP2006550312A patent/JP2007519700A/ja active Pending
2006
- 2006-09-01 NO NO20063917A patent/NO20063917L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1950213B1 (fr)	2009-08-05
WO2005073235A3 (fr)	2005-10-06
RS20060427A (sr)	2008-08-07
HU0400325D0 (en)	2004-04-28
DE602005015902D1 (de)	2009-09-17
HUP0400325A2 (hu)	2005-09-28
DE602005012365D1 (de)	2009-03-05
HUP0400325A3 (en)	2005-11-28
EA200601417A1 (ru)	2006-12-29
EP1711501B1 (fr)	2009-01-14
JP2007519700A (ja)	2007-07-19
ATE438647T1 (de)	2009-08-15
ATE420882T1 (de)	2009-01-15
EA010830B1 (ru)	2008-12-30
EP1711501A2 (fr)	2006-10-18
EP1950213A3 (fr)	2008-08-13
WO2005073235A2 (fr)	2005-08-11
EP1950213A2 (fr)	2008-07-30

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Legal Events

Date	Code	Title	Description
2010-08-23	FC2A	Withdrawal, rejection or dismissal of laid open patent application