NO20080865L - Spirokromanonderivater som acetyl-koenzym-A-karboksylase(ACC)inhibitorer - Google Patents

Spirokromanonderivater som acetyl-koenzym-A-karboksylase(ACC)inhibitorer

Info

Publication number
NO20080865L
NO20080865L NO20080865A NO20080865A NO20080865L NO 20080865 L NO20080865 L NO 20080865L NO 20080865 A NO20080865 A NO 20080865A NO 20080865 A NO20080865 A NO 20080865A NO 20080865 L NO20080865 L NO 20080865L
Authority
NO
Norway
Prior art keywords
acc
carboxylase
coenzyme
acetyl
inhibitors
Prior art date
Application number
NO20080865A
Other languages
English (en)
Norwegian (no)
Inventor
Takeru Yamakawa
Hideki Jona
Kenji Niiyama
Koji Yamada
Tomoharu Iino
Mitsuru Ohkubo
Hideaki Imamura
Jun Kusunoki
Lihu Yang
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of NO20080865L publication Critical patent/NO20080865L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/527—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20080865A 2005-07-19 2008-02-18 Spirokromanonderivater som acetyl-koenzym-A-karboksylase(ACC)inhibitorer NO20080865L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70038205P 2005-07-19 2005-07-19
PCT/US2006/027546 WO2007011811A1 (en) 2005-07-19 2006-07-14 Spirochromanone derivatives as acetyl coenzyme a carboxylase (acc) inhibitors

Publications (1)

Publication Number Publication Date
NO20080865L true NO20080865L (no) 2008-04-18

Family

ID=37317248

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080865A NO20080865L (no) 2005-07-19 2008-02-18 Spirokromanonderivater som acetyl-koenzym-A-karboksylase(ACC)inhibitorer

Country Status (20)

Country Link
US (2) US7935712B2 (de)
EP (1) EP1910375B1 (de)
JP (1) JP5076159B2 (de)
KR (1) KR20080036041A (de)
CN (1) CN101238132A (de)
AR (1) AR054842A1 (de)
AT (1) ATE509023T1 (de)
AU (1) AU2006270145B2 (de)
BR (1) BRPI0613427A2 (de)
CA (1) CA2614963C (de)
DO (1) DOP2006000170A (de)
IL (1) IL188417A0 (de)
MX (1) MX2008000966A (de)
NO (1) NO20080865L (de)
NZ (1) NZ564591A (de)
PE (1) PE20070527A1 (de)
RU (1) RU2422446C2 (de)
TW (1) TW200728307A (de)
WO (2) WO2007011809A1 (de)
ZA (1) ZA200711119B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007011809A1 (en) * 2005-07-19 2007-01-25 Merck & Co., Inc. Spirochromanone derivatives as acetyl coenzyme a carboxylase (acc) inhibitors
EP2061767B1 (de) 2006-08-08 2014-12-17 Sanofi Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
BRPI0721053A2 (pt) * 2006-11-29 2014-07-29 Pfizer Prod Inc INIBIDORES DE ESPIROCETONA ACETIL-CoA CARBOXILASE
AU2008205642B2 (en) * 2007-01-12 2013-06-06 Msd K.K. Spirochromanon derivatives
PE20081559A1 (es) * 2007-01-12 2008-11-20 Merck & Co Inc DERIVADOS DE ESPIROCROMANONA SUSTITUIDOS COMO INHIBIDORES DE ACETIL CoA CARBOXILASA
JPWO2008102749A1 (ja) * 2007-02-20 2010-05-27 武田薬品工業株式会社 複素環化合物
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2009144555A1 (en) * 2008-05-28 2009-12-03 Pfizer Inc. Pyrazolospiroketone acetyl-coa carboxylase inhibitors
JP5435592B2 (ja) * 2008-05-28 2014-03-05 ファイザー・インク ピラゾロスピロケトンアセチルＣｏＡカルボキシラーゼ阻害剤
WO2010002010A1 (en) * 2008-07-04 2010-01-07 Banyu Pharmaceutical Co.,Ltd. Novel spirochromanone carboxylic acids
UY31968A (es) 2008-07-09 2010-01-29 Sanofi Aventis Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
AU2009271634A1 (en) * 2008-07-14 2010-01-21 Cropsolution, Inc. Modulators of acetyl-coenzyme a carboxylase and methods of use thereof
US8324385B2 (en) * 2008-10-30 2012-12-04 Madrigal Pharmaceuticals, Inc. Diacylglycerol acyltransferase inhibitors
US20100113473A1 (en) 2008-10-30 2010-05-06 Player Mark R Aryl amide compound as an acetyl coenzyme a carboxylase inhibitor
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
TW201038572A (en) * 2009-03-25 2010-11-01 Gruenenthal Gmbh Substituted spiro-amide compounds
KR20120060207A (ko) 2009-08-26 2012-06-11 사노피 신규한 결정성 헤테로방향족 플루오로글리코시드 수화물, 이들 화합물을 포함하는 약제 및 이들의 용도
EP2499140A1 (de) * 2009-11-10 2012-09-19 Pfizer Inc. N2-pyrazolospiroketon-acetyl-coa-carboxylasehemmer
EP2947082A1 (de) * 2009-11-10 2015-11-25 Pfizer Inc N1-PYRAZOLOSPIROKETON-ACETYL-CoA-CARBOXYLASEHEMMER
CA2798330A1 (en) 2010-05-05 2011-11-10 Infinity Pharmaceuticals, Inc. Tetrazolones as inhibitors of fatty acid synthase
US8450350B2 (en) 2010-05-05 2013-05-28 Infinity Pharmaceuticals, Inc. Triazoles as inhibitors of fatty acid synthase
US8598164B2 (en) 2010-05-06 2013-12-03 Vertex Pharmaceuticals Incorporated Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
HRP20161178T1 (hr) 2010-09-30 2016-11-04 Pfizer Inc. N1-PIRAZOLOSPIROKETONSKI INHIBITORI ACETIL-CoA-KARBOKSILAZE
ES2546465T3 (es) 2010-10-29 2015-09-23 Pfizer Inc Inhibidores de N1/N2-lactama acetil-CoA carboxilasa
KR101923367B1 (ko) 2011-02-02 2018-12-04 버텍스 파마슈티칼스 인코포레이티드 이온 채널의 조절제로서의 피롤로피라진―스피로사이클릭 피페리딘 아미드
MX2013009393A (es) * 2011-02-18 2013-08-29 Vertex Pharma Piperidinamidas cromano-espirociclicas como moduladores de canales de iones.
WO2012120056A1 (de) 2011-03-08 2012-09-13 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683704B1 (de) 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2766349B1 (de) 2011-03-08 2016-06-01 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
CN103517910B (zh) 2011-03-14 2016-12-14 沃泰克斯药物股份有限公司 作为离子通道调节剂的吗啉-螺环哌啶酰胺
AU2012245996B2 (en) 2011-04-22 2016-09-01 Pfizer Inc. Pyrazolospiroketone derivatives for use as acetyl-CoA carboxylase inhibitors
TW201300393A (zh) * 2011-05-20 2013-01-01 Kowa Co 新穎之螺哌啶衍生物及含有其之醫藥
EP3670496A3 (de) 2013-10-17 2020-09-30 Shionogi&Co., Ltd. Acc2 hemmer
CA3046805A1 (en) 2016-12-14 2018-06-21 89Bio Ltd. Spiropiperidine derivatives
CN110799187B (zh) 2017-06-30 2023-10-03 汇科锦公司 螺内酯化合物
WO2019099457A1 (en) * 2017-11-14 2019-05-23 Quixgen, Inc. Benzodioxinone compounds
AU2019318209B2 (en) 2018-08-10 2025-09-25 Diapin Therapeutics, Llc Tri-peptides and treatment of metabolic, cardiovascular and inflammatory disorders
CN121909191A (zh) * 2023-08-16 2026-04-21 智擎生技制药股份有限公司 Mta协同性的prmt5抑制剂

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2535338A1 (de) * 1975-08-07 1977-02-17 Bayer Ag Chromanone-(4)
DE2814983A1 (de) 1978-04-07 1979-10-18 Bayer Ag Neue chromanon-derivate
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
US5206240A (en) * 1989-12-08 1993-04-27 Merck & Co., Inc. Nitrogen-containing spirocycles
CA2154569A1 (en) 1993-01-28 1994-08-04 Jeffrey J. Hale Spiro-substituted azacycles as tachykinin receptor antagonists
US5563716A (en) * 1994-01-24 1996-10-08 Victor Company Of Japan, Ltd. Video signal reproducing method and apparatus
CA2189634A1 (en) 1994-05-06 1995-11-16 John J. Baldwin Combinatorial dihydrobenzopyran library
AU705661B2 (en) 1995-06-06 1999-05-27 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
GB9601724D0 (en) 1996-01-29 1996-03-27 Merck Sharp & Dohme Therapeutic agents
TWI243173B (en) * 1999-11-17 2005-11-11 Akzo Nobel Nv Spiro[2H-1-benzopyran-2,4'-piperidine] derivatives
JP3961793B2 (ja) * 2001-08-08 2007-08-22 大日本スクリーン製造株式会社 基板洗浄方法
JP2003059871A (ja) * 2001-08-10 2003-02-28 Sekisui Chem Co Ltd Ｉｃチップの製造方法
JP2003094912A (ja) * 2001-09-26 2003-04-03 Bridgestone Corp ランフラットタイヤ及びその製造方法
CN1642599A (zh) * 2002-02-27 2005-07-20 辉瑞产品公司 Acc抑制剂
JP4004898B2 (ja) * 2002-08-30 2007-11-07 成和樹脂工業株式会社 クランプ用カバー
WO2004092179A1 (ja) 2003-04-14 2004-10-28 Nippon Soda Co. Ltd. スピロ誘導体、製造法および抗酸化薬
JP2005119987A (ja) 2003-10-15 2005-05-12 Ajinomoto Co Inc アシルスルホンアミド誘導体
CN101103016A (zh) 2004-11-18 2008-01-09 因塞特公司 11-β羟基类固醇脱氢酶1型抑制剂及其使用方法
WO2007011809A1 (en) * 2005-07-19 2007-01-25 Merck & Co., Inc. Spirochromanone derivatives as acetyl coenzyme a carboxylase (acc) inhibitors
AU2008205642B2 (en) * 2007-01-12 2013-06-06 Msd K.K. Spirochromanon derivatives
PE20081559A1 (es) * 2007-01-12 2008-11-20 Merck & Co Inc DERIVADOS DE ESPIROCROMANONA SUSTITUIDOS COMO INHIBIDORES DE ACETIL CoA CARBOXILASA

Also Published As

Publication number Publication date
EP1910375B1 (de) 2011-05-11
WO2007011809A1 (en) 2007-01-25
JP2009502785A (ja) 2009-01-29
US7410976B2 (en) 2008-08-12
WO2007011811A1 (en) 2007-01-25
KR20080036041A (ko) 2008-04-24
CA2614963A1 (en) 2007-01-25
AU2006270145B2 (en) 2011-04-14
IL188417A0 (en) 2008-11-03
CA2614963C (en) 2014-10-07
AR054842A1 (es) 2007-07-18
PE20070527A1 (es) 2007-06-14
RU2422446C2 (ru) 2011-06-27
ATE509023T1 (de) 2011-05-15
DOP2006000170A (es) 2007-03-31
RU2008106243A (ru) 2009-08-27
MX2008000966A (es) 2008-03-26
BRPI0613427A2 (pt) 2012-10-30
EP1910375A1 (de) 2008-04-16
TW200728307A (en) 2007-08-01
US7935712B2 (en) 2011-05-03
NZ564591A (en) 2010-01-29
AU2006270145A1 (en) 2007-01-25
CN101238132A (zh) 2008-08-06
ZA200711119B (en) 2009-12-30
US20090131464A1 (en) 2009-05-21
US20070021453A1 (en) 2007-01-25
JP5076159B2 (ja) 2012-11-21

Similar Documents

Publication Publication Date Title
NO20080865L (no) Spirokromanonderivater som acetyl-koenzym-A-karboksylase(ACC)inhibitorer
NO20090835L (no) Nye HIV-reverstranskriptaseinhibitorer
NO20083567L (no) Hydantoinderivater for behandling av inflammatoriske forstyrrelser
NO20072978L (no) Nye betuinderivater, preparat derav og anvendelse derav
ATE540932T1 (de) Hydantoin-derivate als antibakterielle wirkstoffe
NO20082090L (no) Pyridopyrimidinoninhibitorer av P13K alfa
TW200833675A (en) Nicotinamide derivatives
EA201101672A1 (ru) Замещенные производные аминомасляной кислоты в качестве ингибиторов неприлизина
EA200970585A1 (ru) Бензамидные производные как агонисты ер-рецепторов
NO20073791L (no) Pyrazolylaminopyridinderivater anvendbare som kinaseinhibitorer
EA201200669A1 (ru) ПИРИДОПИРИМИДИНОНОВЫЕ ИНГИБИТОРЫ PI3Kα
NO20091858L (no) Hydrobenzamid derivater som inhibitorer av HSP90
NO20081315L (no) Benzokinazolinderivater og deres anvendelse ved behandling av benlidelser
EA201000805A1 (ru) Бис-(сульфониламино)производные в терапии 066
BRPI0513433A (pt) derivados de hidantoìna para o tratamento de distúrbios inflamatórios
TW200736248A (en) Compounds for the treatment of inflammatory disorders
SE0400284D0 (sv) Novel compounds
EA200701745A1 (ru) Циклопропанкарбоксамидные производные
NO20083708L (no) 4-Fenyl-tiazol-5-karboksylsyre og 4-fenyl-tiazol-5-karboksylmider som PLK1-inhibitorer
MX2010004232A (es) Compuesto de indolina de pirimidilo.
MX2009010302A (es) Derivados de indol que tienen actividad inhibidora de cpla2 y aplicaciones y metodos de produccion.
WO2013038429A3 (en) Novel sglt inhibitors
EA201270359A1 (ru) Терапевтическое средство от расстройств настроения
EA201100994A1 (ru) Способ получения производных бисфуранового спирта, соединения, соль, фармацевтическая композиция на ее основе, способ лечения или профилактики ретровирусных инфекций с ее помощью
DK1753723T3 (da) Substituerede quinolinderivater som mitotiske kinesininhibitorer

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application