NO20082708L - Terapeutisk middel for tarmbetennelse inneholdende 2-amino-1,3-propandiolderivat som aktiv forbindelse, og metode for behandling av tarmbetennelse - Google Patents
Terapeutisk middel for tarmbetennelse inneholdende 2-amino-1,3-propandiolderivat som aktiv forbindelse, og metode for behandling av tarmbetennelseInfo
- Publication number
- NO20082708L NO20082708L NO20082708A NO20082708A NO20082708L NO 20082708 L NO20082708 L NO 20082708L NO 20082708 A NO20082708 A NO 20082708A NO 20082708 A NO20082708 A NO 20082708A NO 20082708 L NO20082708 L NO 20082708L
- Authority
- NO
- Norway
- Prior art keywords
- amino
- intestinal
- disease
- therapeutic agent
- active compound
- Prior art date
Links
- KJJPLEZQSCZCKE-UHFFFAOYSA-N 2-aminopropane-1,3-diol Chemical class OCC(N)CO KJJPLEZQSCZCKE-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000000968 intestinal effect Effects 0.000 title 2
- 206010061218 Inflammation Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 208000011231 Crohn disease Diseases 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- JGCZBUBEWYTICT-UHFFFAOYSA-N 5-amino-5-[2-chloro-4-(3-phenylmethoxyphenyl)sulfanylphenyl]pentane-1,3-diol;hydrochloride Chemical compound Cl.C1=C(Cl)C(C(CC(O)CCO)N)=CC=C1SC1=CC=CC(OCC=2C=CC=CC=2)=C1 JGCZBUBEWYTICT-UHFFFAOYSA-N 0.000 abstract 1
- 208000009137 Behcet syndrome Diseases 0.000 abstract 1
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
- 208000002389 Pouchitis Diseases 0.000 abstract 1
- 206010038063 Rectal haemorrhage Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229940125700 inflammatory bowel disease agent Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006027883 | 2006-02-06 | ||
| PCT/JP2007/051887 WO2007091501A1 (fr) | 2006-02-06 | 2007-02-05 | Agent thérapeutique pour une affection abdominale inflammatoire qui comprend un dérivé de 2-amino-1,3-propanediol en tant qu'ingrédient actif et procédé pour le traitement d'une affection abdominale inflammatoire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20082708L true NO20082708L (no) | 2008-09-02 |
Family
ID=38345101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20082708A NO20082708L (no) | 2006-02-06 | 2008-06-12 | Terapeutisk middel for tarmbetennelse inneholdende 2-amino-1,3-propandiolderivat som aktiv forbindelse, og metode for behandling av tarmbetennelse |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8318811B2 (fr) |
| EP (2) | EP1982708B1 (fr) |
| JP (1) | JP5042042B2 (fr) |
| KR (1) | KR101334153B1 (fr) |
| CN (1) | CN101378743B (fr) |
| AU (1) | AU2007213194B9 (fr) |
| BR (1) | BRPI0706971A2 (fr) |
| CA (1) | CA2641546C (fr) |
| CY (1) | CY1116112T1 (fr) |
| DK (1) | DK1982708T3 (fr) |
| EC (1) | ECSP088662A (fr) |
| ES (1) | ES2524056T3 (fr) |
| GT (1) | GT200800148A (fr) |
| HR (1) | HRP20080421B1 (fr) |
| IL (1) | IL192150A (fr) |
| MA (1) | MA31338B1 (fr) |
| MX (1) | MX2008008872A (fr) |
| MY (1) | MY151193A (fr) |
| NO (1) | NO20082708L (fr) |
| NZ (1) | NZ568907A (fr) |
| PL (1) | PL1982708T3 (fr) |
| PT (1) | PT1982708E (fr) |
| RU (1) | RU2428976C2 (fr) |
| SG (1) | SG169370A1 (fr) |
| SI (1) | SI1982708T1 (fr) |
| TN (1) | TNSN08246A1 (fr) |
| TW (1) | TWI389683B (fr) |
| WO (1) | WO2007091501A1 (fr) |
| ZA (1) | ZA200806199B (fr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7781617B2 (en) | 2004-07-16 | 2010-08-24 | Kyorin Pharmaceutical Co., Ltd | Effective use method of medicaments and method of preventing expression of side effect |
| EP1806338B1 (fr) | 2004-10-12 | 2016-01-20 | Kyorin Pharmaceutical Co., Ltd. | Procédé de synthèse de l hydrochlorure de 2-amino-2-[2-[4-(3-benzyloxy-phénylthio)-2-chlorophényl[éthyl]-1,3-propanediol et des hydrates de ce composé, et intermédiaires de synthèse de celles-ci |
| PL1932522T3 (pl) | 2005-10-07 | 2012-09-28 | Kyorin Seiyaku Kk | Środek terapeutyczny do leczenia choroby wątroby zawierający jako składnik czynny pochodną 2-amino-1,3-propanodiolu |
| TWI389683B (zh) | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| CA2659598A1 (fr) | 2006-08-08 | 2008-02-14 | Kyorin Pharmaceutical Co., Ltd. | Derive d'ester de l'acide aminophosphorique et modulateur durecepteur s1p contenant ledit derive en tant que principe actif |
| JP5140593B2 (ja) | 2006-08-08 | 2013-02-06 | 杏林製薬株式会社 | アミノアルコール誘導体及びそれらを有効成分とする免疫抑制剤 |
| TW200946105A (en) | 2008-02-07 | 2009-11-16 | Kyorin Seiyaku Kk | Therapeutic agent or preventive agent for inflammatory bowel disease containing amino alcohol derivative as active ingredient |
| CA2724592A1 (fr) * | 2008-05-20 | 2009-11-26 | Kyorin Pharmaceutical Co., Ltd. | Agent d~induction/d~entretien de remission |
| US8580841B2 (en) | 2008-07-23 | 2013-11-12 | Arena Pharmaceuticals, Inc. | Substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders |
| HRP20160890T1 (hr) | 2008-08-27 | 2016-09-23 | Arena Pharmaceuticals, Inc. | Derivati supstituirane tricikličke kiseline kao agonisti s1p1-receptora korisni u liječenju autoimunih i upalnih poremećaja |
| EP2177521A1 (fr) | 2008-10-14 | 2010-04-21 | Almirall, S.A. | Nouveaux dérivés de 2-amidothiadiazole |
| WO2010051030A1 (fr) * | 2008-10-30 | 2010-05-06 | Biogen Idec Ma Inc. | Analogues de sphingosine 1-phosphate d’aryle bicyclique |
| EP2202232A1 (fr) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | Dérivés du 1,2,4-oxadiazole et leur application thérapeutique |
| EP2210890A1 (fr) | 2009-01-19 | 2010-07-28 | Almirall, S.A. | Dérivés d'oxadiazoles en tant qu'agonistes du récepteur S1P1 |
| EP2305660A1 (fr) | 2009-09-25 | 2011-04-06 | Almirall, S.A. | Nouveaux dérivés de thiadiazole |
| EP2343287A1 (fr) | 2009-12-10 | 2011-07-13 | Almirall, S.A. | Nouveaux dérivés de 2-aminothiadiazole |
| JP5856980B2 (ja) | 2010-01-27 | 2016-02-10 | アリーナ ファーマシューティカルズ, インコーポレイテッド | (R)−2−(7−(4−シクロペンチル−3−(トリフルオロメチル)ベンジルオキシ)−1,2,3,4−テトラヒドロシクロペンタ[b]インドール−3−イル)酢酸およびその塩の調製のためのプロセス |
| CN105503882B (zh) | 2010-03-03 | 2019-07-05 | 艾尼纳制药公司 | 制备s1p1受体调节剂及其晶体形式的方法 |
| EP2366702A1 (fr) | 2010-03-18 | 2011-09-21 | Almirall, S.A. | Nouveaux dérivés d'oxadiazole |
| EP2390252A1 (fr) | 2010-05-19 | 2011-11-30 | Almirall, S.A. | Nouveaux dérivés de pyrazole |
| EP2455081A1 (fr) * | 2010-11-23 | 2012-05-23 | Almirall, S.A. | Agonistes de récepteur S1P1 à utiliser dans le traitement de la maladie de Crohn |
| AR085749A1 (es) | 2011-04-01 | 2013-10-23 | Novartis Ag | Formulaciones |
| KR101787543B1 (ko) | 2014-08-22 | 2017-10-19 | 샘표식품 주식회사 | 발효배양 산삼을 포함하는 항염증 조성물 |
| PL3242666T3 (pl) | 2015-01-06 | 2025-02-17 | Arena Pharmaceuticals, Inc. | Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1 |
| BR112017027656B1 (pt) | 2015-06-22 | 2023-12-05 | Arena Pharmaceuticals, Inc. | Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo |
| MX2019009841A (es) | 2017-02-16 | 2020-01-30 | Arena Pharm Inc | Compuestos y metodos para el tratamiento de la colangitis biliar primaria. |
| MX2019009843A (es) | 2017-02-16 | 2020-01-30 | Arena Pharm Inc | Compuestos y metodos para el tratamiento de la enfermedad inflamatoria intestinal con manifestaciones extraintestinales. |
| CA3102136A1 (fr) | 2018-06-06 | 2019-12-12 | Arena Pharmaceuticals, Inc. | Methodes de traitement de troubles associes au recepteur s1p1<sb /> |
| IL280451B2 (en) | 2018-07-27 | 2025-10-01 | Priothera Ltd | A preparation for preventing recurrence of proliferative blood disease in patients who have undergone hematopoietic stem cell transplantation |
| CN112955431A (zh) | 2018-09-06 | 2021-06-11 | 艾尼纳制药公司 | 可用于治疗自身免疫性病症和炎性病症的化合物 |
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| DE69321823T2 (de) | 1992-10-21 | 1999-06-02 | Taito Co., Ltd., Tokio/Tokyo | 2-amino-1, 3- propandiolverbindung und immunosuppressium |
| US5948820A (en) | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
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2007
- 2007-01-25 TW TW096102882A patent/TWI389683B/zh not_active IP Right Cessation
- 2007-02-05 DK DK07713815.4T patent/DK1982708T3/en active
- 2007-02-05 MY MYPI20082159 patent/MY151193A/en unknown
- 2007-02-05 US US12/223,584 patent/US8318811B2/en active Active
- 2007-02-05 JP JP2007557819A patent/JP5042042B2/ja not_active Expired - Fee Related
- 2007-02-05 KR KR1020087017968A patent/KR101334153B1/ko not_active Expired - Fee Related
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- 2007-02-05 CN CN200780004468.6A patent/CN101378743B/zh not_active Expired - Fee Related
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- 2007-02-05 WO PCT/JP2007/051887 patent/WO2007091501A1/fr not_active Ceased
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- 2007-02-05 CA CA2641546A patent/CA2641546C/fr not_active Expired - Fee Related
- 2007-02-05 EP EP12167430A patent/EP2520291A1/fr not_active Withdrawn
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