NO20083480L - Piperidinoylpyrrolidiner som melanokortin type 4 reseptor agonister - Google Patents

Piperidinoylpyrrolidiner som melanokortin type 4 reseptor agonister

Info

Publication number
NO20083480L
NO20083480L NO20083480A NO20083480A NO20083480L NO 20083480 L NO20083480 L NO 20083480L NO 20083480 A NO20083480 A NO 20083480A NO 20083480 A NO20083480 A NO 20083480A NO 20083480 L NO20083480 L NO 20083480L
Authority
NO
Norway
Prior art keywords
piperidinoylpyrrolidines
receptor agonists
melanocortin
melanocortin type
type
Prior art date
Application number
NO20083480A
Other languages
English (en)
Norwegian (no)
Inventor
Mark David Andrews
Alan Daniel Brown
Mark Ian Landsdell
Nicholas William Summerhill
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of NO20083480L publication Critical patent/NO20083480L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20083480A 2006-02-23 2008-08-11 Piperidinoylpyrrolidiner som melanokortin type 4 reseptor agonister NO20083480L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77629506P 2006-02-23 2006-02-23
US88784007P 2007-02-02 2007-02-02
PCT/IB2007/000456 WO2007096763A2 (fr) 2006-02-23 2007-02-19 Pipéridinoylpyrrolidines en tant qu'agonistes du récepteur de la mélanocortine de type 4

Publications (1)

Publication Number Publication Date
NO20083480L true NO20083480L (no) 2008-09-10

Family

ID=38169450

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083480A NO20083480L (no) 2006-02-23 2008-08-11 Piperidinoylpyrrolidiner som melanokortin type 4 reseptor agonister

Country Status (21)

Country Link
US (1) US8138188B2 (fr)
EP (1) EP1989196B1 (fr)
KR (1) KR101036981B1 (fr)
AP (1) AP2008004602A0 (fr)
AU (1) AU2007219236B2 (fr)
BR (1) BRPI0708264A2 (fr)
CA (1) CA2642922C (fr)
CR (1) CR10219A (fr)
DK (1) DK1989196T3 (fr)
EA (1) EA200801738A1 (fr)
EC (1) ECSP088688A (fr)
ES (1) ES2402581T3 (fr)
IL (1) IL193279A (fr)
MA (1) MA30228B1 (fr)
ME (1) MEP6808A (fr)
MX (1) MX2008010899A (fr)
NO (1) NO20083480L (fr)
RS (1) RS20080371A (fr)
SG (1) SG185849A1 (fr)
TN (1) TNSN08337A1 (fr)
WO (1) WO2007096763A2 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2019100A1 (fr) * 2007-07-19 2009-01-28 Santhera Pharmaceuticals (Schweiz) AG Dérivés substitués d'hétéroarylpipéridine en tant que modulateurs du récepteur de la mélanocortine-4
EP2025674A1 (fr) 2007-08-15 2009-02-18 sanofi-aventis Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament
US8737295B2 (en) 2007-11-16 2014-05-27 Qualcomm Incorporated Sector identification using sector parameters signatures
US9603062B2 (en) 2007-11-16 2017-03-21 Qualcomm Incorporated Classifying access points using pilot identifiers
US8848656B2 (en) 2007-11-16 2014-09-30 Qualcomm Incorporated Utilizing broadcast signals to convey restricted association information
US8902867B2 (en) 2007-11-16 2014-12-02 Qualcomm Incorporated Favoring access points in wireless communications
EP2103614A1 (fr) * 2008-03-18 2009-09-23 Santhera Pharmaceuticals (Schweiz) AG Dérivés d'imidazopyrimidine, d'imidazopyrazine et d' imidazopyridazine substitués en tant que modulateur de récepteur de la mélanocortine-4
US8588773B2 (en) 2008-08-04 2013-11-19 Qualcomm Incorporated System and method for cell search and selection in a wireless communication system
UA99555C2 (en) 2008-11-12 2012-08-27 Элджи Лайф Саенсез Лтд. Melanocortin receptor agonists
EP2722045B1 (fr) 2009-11-18 2016-07-06 Helsinn Healthcare SA Compositions pour traiter les nausées et vomissements à médiation centrale
ES2623503T3 (es) * 2009-11-18 2017-07-11 Helsinn Healthcare Sa Composiciones para tratar náuseas y vómitos mediados centralmente
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120056A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés oxathiazine tétra-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
EP2683699B1 (fr) 2011-03-08 2015-06-24 Sanofi Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
EP2683704B1 (fr) 2011-03-08 2014-12-17 Sanofi Dérivés oxathiazine ramifiés, procédé pour leur préparation, utilisation en tant que médicament, agents pharmaceutiques contenant ces dérivés et leur utilisation
EP2766349B1 (fr) 2011-03-08 2016-06-01 Sanofi Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation
EP3333165B1 (fr) 2015-08-04 2019-09-18 Astellas Pharma Inc. Dérivé de pipérazine
US20210393621A1 (en) 2018-10-26 2021-12-23 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
JP7288554B1 (ja) 2020-06-09 2023-06-07 ファイザー・インク メラノコルチン４受容体アンタゴニストとしてのスピロ化合物およびそれらの使用
JP2024544021A (ja) 2021-12-06 2024-11-26 ファイザー・インク メラノコルチン４受容体アンタゴニストおよびそれらの使用
US20250333414A1 (en) 2024-04-30 2025-10-30 Boehringer Ingelheim International Gmbh Hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228900A1 (fr) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Indazoles substitués par arylamide et leur utilisation en tant que médicament
US20250333398A1 (en) 2024-04-30 2025-10-30 Boehringer Ingelheim International Gmbh Monoaryl and hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228902A1 (fr) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Acides hétérocycliques en tant qu'antagonistes de sting et leur utilisation en tant que médicament
WO2025228889A1 (fr) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Composés hétérocycliques monoaryliques utilisés en tant qu'antagonistes de sting et leur utilisation en tant que médicament
WO2025228899A1 (fr) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Autres composés hétérocycliques utilisés en tant qu'antagonistes de sting et leur utilisation en tant que médicament
US12605394B2 (en) 2024-07-25 2026-04-21 Visionary Assets, Llc Compositions containing cannabinoid nanoparticles

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH507249A (de) * 1968-05-31 1971-05-15 Sandoz Ag Verfahren zur Herstellung von 2-Brom-a-ergokryptin
GB8531071D0 (en) * 1985-12-17 1986-01-29 Boots Co Plc Therapeutic compound
US5274143A (en) * 1991-07-23 1993-12-28 Hoffmann-La Roche Inc. Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-pyran-2-one and (R)-5,6-dihydro-6-undecyl-2H-pyran-2,4(3H)-dione
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
CA2098167C (fr) * 1992-06-24 2006-12-19 Dorothea Isler Aliments pour humains et animaux contenant un inhibiteur de la lipase
TW381025B (en) * 1993-08-05 2000-02-01 Hoffmann La Roche Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor
US5596106A (en) * 1994-07-15 1997-01-21 Eli Lilly And Company Cannabinoid receptor antagonists
DE4435477A1 (de) * 1994-10-04 1996-04-11 Bayer Ag Cycloalkano-indol- und -azaindol-derivate
DE122007000005I2 (de) * 1994-10-27 2008-04-24 Janssen Pharmaceutica Nv Apolipoprotein-b syntheseinhibitoren
US5521186A (en) * 1994-10-27 1996-05-28 Janssen Pharmaceutica N.V. Apolipoprotein-β synthesis inhibitors
WO2000035296A1 (fr) 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Liberation amelioree d'agents medicamenteux actifs par un enrobage de chewing-gum
KR100652994B1 (ko) * 1998-09-11 2006-11-30 아방티 파르마 소시에테 아노님 아제티딘 유도체, 이의 제조방법 및 이를 함유하는 약제
FR2789079B3 (fr) * 1999-02-01 2001-03-02 Sanofi Synthelabo Derive d'acide pyrazolecarboxylique, sa preparation, les compositions pharmaceutiques en contenant
EP2123293A3 (fr) 2000-12-14 2010-09-08 Amylin Pharmaceuticals, Inc. Peptide YY et agonistes du peptide YY pour le traitement de troubles métaboliques
DE60215132T2 (de) 2001-02-28 2007-08-23 Merck & Co., Inc. Acylierte piperidin-derivate als melanocortin-4-rezeptor-agonisten
CA2439152C (fr) 2001-02-28 2008-06-17 Merck & Co., Inc. Derives de piperidine acylee tels que les agonistes du recepteur 4 de la melanocortine
PL363751A1 (en) 2001-03-22 2004-11-29 Solvay Pharmaceuticals B.V. 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity
JP2005514008A (ja) 2001-09-24 2005-05-19 オレゴン ヘルス アンド サイエンス ユニバーシティー 摂食行動を改変する薬剤をスクリーニングするための、弓状核におけるニューロンの評価方法
EP1482794A1 (fr) 2002-03-06 2004-12-08 Merck & Co., Inc. Methode de traitement ou de prevention de l'obesite
JP4202319B2 (ja) 2002-07-29 2008-12-24 エフ．ホフマン−ラ ロシュ アーゲー 新規ベンゾジオキソール
EP1558252B1 (fr) 2002-08-02 2007-10-10 Merck & Co., Inc. Derives de furo[2,3-b]pyridine substitues
US7129239B2 (en) 2002-10-28 2006-10-31 Pfizer Inc. Purine compounds and uses thereof
MY134457A (en) 2002-11-22 2007-12-31 Merck & Co Inc Substituted amides
US7329658B2 (en) 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US7141669B2 (en) 2003-04-23 2006-11-28 Pfizer Inc. Cannabiniod receptor ligands and uses thereof
US7145012B2 (en) 2003-04-23 2006-12-05 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
US7151097B2 (en) * 2003-11-07 2006-12-19 Pfizer Inc. Bicyclic pyrazolyl and imidazolyl compounds and uses thereof
US7649002B2 (en) 2004-02-04 2010-01-19 Pfizer Inc (3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists
GB0402492D0 (en) * 2004-02-04 2004-03-10 Pfizer Ltd Pharmaceutically active compounds
CA2617654A1 (fr) * 2005-08-04 2007-02-08 Pfizer Limited Composes piperidinoyl-pyrrolidine et piperidinoyl-piperidine
KR101280786B1 (ko) 2008-08-06 2013-07-05 화이자 리미티드 멜라노코르틴 4 작용제로서 다이아제핀 및 다이아조칸 화합물

Also Published As

Publication number Publication date
AU2007219236A1 (en) 2007-08-30
MA30228B1 (fr) 2009-02-02
AP2008004602A0 (en) 2008-10-31
US20090036459A1 (en) 2009-02-05
EA200801738A1 (ru) 2008-12-30
AU2007219236B2 (en) 2012-06-21
CR10219A (es) 2008-09-23
EP1989196B1 (fr) 2013-02-13
IL193279A0 (en) 2009-02-11
KR101036981B1 (ko) 2011-05-25
CA2642922C (fr) 2011-08-02
MEP6808A (xx) 2010-02-10
US8138188B2 (en) 2012-03-20
BRPI0708264A2 (pt) 2011-05-24
MX2008010899A (es) 2008-11-27
RS20080371A (sr) 2009-07-15
IL193279A (en) 2012-12-31
EP1989196A2 (fr) 2008-11-12
TNSN08337A1 (fr) 2009-12-29
KR20080095918A (ko) 2008-10-29
DK1989196T3 (da) 2013-04-15
ES2402581T3 (es) 2013-05-06
HK1126489A1 (en) 2009-09-04
WO2007096763A3 (fr) 2007-10-18
ECSP088688A (es) 2008-10-31
SG185849A1 (en) 2012-12-28
WO2007096763A2 (fr) 2007-08-30
CA2642922A1 (fr) 2007-08-30

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