NO20084897L - Ny forbindelse med affinitet til amuloid - Google Patents

Ny forbindelse med affinitet til amuloid

Info

Publication number
NO20084897L
NO20084897L NO20084897A NO20084897A NO20084897L NO 20084897 L NO20084897 L NO 20084897L NO 20084897 A NO20084897 A NO 20084897A NO 20084897 A NO20084897 A NO 20084897A NO 20084897 L NO20084897 L NO 20084897L
Authority
NO
Norway
Prior art keywords
compound
affinity
amuloid
integer
new compound
Prior art date
Application number
NO20084897A
Other languages
English (en)
Norwegian (no)
Inventor
Daisaku Nakamura
Shigeyuki Tanifuji
Shinya Takasaki
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Publication of NO20084897L publication Critical patent/NO20084897L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20084897A 2006-04-28 2008-11-20 Ny forbindelse med affinitet til amuloid NO20084897L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006124811 2006-04-28
PCT/JP2007/059048 WO2007125988A1 (ja) 2006-04-28 2007-04-26 新規アミロイド親和性化合物

Publications (1)

Publication Number Publication Date
NO20084897L true NO20084897L (no) 2009-01-15

Family

ID=38655513

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084897A NO20084897L (no) 2006-04-28 2008-11-20 Ny forbindelse med affinitet til amuloid

Country Status (16)

Country Link
US (2) US8022207B2 (de)
EP (1) EP2022792B1 (de)
JP (1) JP5048655B2 (de)
KR (1) KR20080112343A (de)
CN (1) CN101472923A (de)
AT (1) ATE493410T1 (de)
AU (1) AU2007244313B2 (de)
CA (1) CA2657312A1 (de)
DE (1) DE602007011601D1 (de)
ES (1) ES2355079T3 (de)
IL (1) IL194889A0 (de)
NO (1) NO20084897L (de)
NZ (1) NZ572741A (de)
RU (1) RU2008147002A (de)
TW (1) TW200803903A (de)
WO (1) WO2007125988A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8303935B2 (en) 2006-05-19 2012-11-06 Nihon Medi-Physics Co., Ltd. Alkoxy substituted imidazo[1,2-a]pyridines having affinity for amyloid
US20090252680A1 (en) * 2006-11-17 2009-10-08 Nihon- Medi-Physics Co., Ltd Novel compound with affinity for amyloid
CA2670436A1 (en) 2006-11-30 2008-06-05 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
KR20100091965A (ko) * 2007-10-24 2010-08-19 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
AU2008314871A1 (en) * 2007-10-26 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
CA2704168A1 (en) * 2007-10-30 2009-05-07 Nihon Medi-Physics Co., Ltd. Use of novel compound having affinity for amyloid, and process for production of the same
EP2218464A1 (de) * 2009-02-11 2010-08-18 Technische Universität München Verbindungen zur nichtinvasiven Messung von Aggregaten von Amyloidpeptiden
US9926316B2 (en) * 2016-03-03 2018-03-27 The Cleveland Clinic Foundation Antitumor derivatives for differentiation therapy
CN108822105A (zh) * 2018-08-14 2018-11-16 河南师范大学 一种由乙苯类化合物合成2-芳基咪唑并[1,2-a]吡啶类化合物的方法
US12551576B2 (en) 2020-01-31 2026-02-17 The General Hospital Corporation Chemiluminescent probes

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4833149A (en) * 1986-09-22 1989-05-23 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines
US4791117A (en) * 1986-09-22 1988-12-13 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines and their use as calcium channel blockers
US4727145A (en) * 1986-09-22 1988-02-23 Ortho Pharmaceutical Corporation 2- Or 3- aryl substituted imidazo [1,2-a]pyridines
US4871745A (en) * 1986-09-22 1989-10-03 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo(1,2-A)pyridines and their use as antisecretory agents
BR9611047A (pt) * 1995-10-17 2000-03-08 Searle & Co Processo de deteção de ciclo oxigenase-2
US6812327B1 (en) * 1996-10-25 2004-11-02 Human Genome Sciences, Inc. Neutrokine-alpha polypeptides
AU759945B2 (en) * 1998-08-20 2003-05-01 Regents Of The University Of California, The Methods for labeling beta-amyloid plaques and neurofibrillary tangles
US20010051632A1 (en) * 2000-03-31 2001-12-13 Wenying Chai Phenyl-substituted indolizines and tetrahydroindolizines
DE10040016A1 (de) 2000-08-16 2002-02-28 Boehringer Ingelheim Pharma Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US6514969B2 (en) * 2000-08-16 2003-02-04 Boehringer Ingelheim Pharma Kg β-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions
RU2324686C2 (ru) * 2000-08-24 2008-05-20 Юнивесити Оф Питсбэг ПРОИЗВОДНЫЕ ТИОФЛАВИНА, СВЯЗЫВАЮЩИЕ АМИЛОИД, СПОСОБ ОБНАРУЖЕНИЯ in vivo ОТЛОЖЕНИЙ АМИЛОИДА И СПОСОБ РАСПОЗНАВАНИЯ БОЛЕЗНИ АЛЬЦГЕЙМЕРА
CZ20032597A3 (cs) * 2001-02-26 2004-12-15 Bristol-Myers Squibb Pharma Company Analogy kyseliny askorbové pro metaloradiofarmaceutika
US6596731B2 (en) * 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
CA2444214A1 (en) * 2001-04-23 2002-10-31 The Trustees Of The University Of Pennsylvania Amyloid plaque aggregation inhibitors and diagnostic imaging agents
CN1299777C (zh) * 2001-08-27 2007-02-14 宾夕法尼亚州大学理事会 茋衍生物及其用于结合和成像淀粉样蛋白斑的用途
GB0205281D0 (en) * 2002-03-06 2002-04-17 Novartis Ag Organic compounds
EP1356827A1 (de) * 2002-04-24 2003-10-29 Mallinckrodt Inc. Verfahren zur Herstellung von einer 2-18F-Fluor-2-Deoxy-D-Glucose (18F-FDG)-Lösung
WO2003106439A1 (ja) 2002-06-12 2003-12-24 株式会社ビーエフ研究所 アミロイド蓄積性疾患の画像診断プローブ化合物、老人斑／びまん性老人斑染色用化合物、ならびにアミロイド蓄積性疾患の治療薬
EP1547996A4 (de) * 2002-08-30 2006-08-02 Bf Res Inst Inc Diagnostische sonden und heilmittel für krankheiten, bei denen prionprotein akkumuliert wird, und anfürbereagenzien für prionprotein
GB0229695D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase preparation of 18F-labelled amino acids
BRPI0418328A (pt) * 2003-12-31 2007-05-02 Schering Plough Ltd controle de parasitas em animais pelo uso de derivados de imidazo [1,2-b]piridazina
US8303935B2 (en) * 2006-05-19 2012-11-06 Nihon Medi-Physics Co., Ltd. Alkoxy substituted imidazo[1,2-a]pyridines having affinity for amyloid
WO2007148755A1 (ja) 2006-06-21 2007-12-27 Nihon Medi-Physics Co., Ltd. 新規アミロイド親和性化合物
US20090252680A1 (en) 2006-11-17 2009-10-08 Nihon- Medi-Physics Co., Ltd Novel compound with affinity for amyloid
CA2670436A1 (en) * 2006-11-30 2008-06-05 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
KR20100091965A (ko) * 2007-10-24 2010-08-19 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물
AU2008314871A1 (en) * 2007-10-26 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
KR20100101577A (ko) * 2007-10-30 2010-09-17 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물의 사용 및 제조 방법

Also Published As

Publication number Publication date
ATE493410T1 (de) 2011-01-15
ES2355079T3 (es) 2011-03-22
WO2007125988A1 (ja) 2007-11-08
JP5048655B2 (ja) 2012-10-17
JPWO2007125988A1 (ja) 2009-09-10
EP2022792B1 (de) 2010-12-29
EP2022792A8 (de) 2009-04-29
US20100249407A1 (en) 2010-09-30
AU2007244313A1 (en) 2007-11-08
US20110201808A1 (en) 2011-08-18
EP2022792A1 (de) 2009-02-11
IL194889A0 (en) 2011-08-01
AU2007244313B2 (en) 2011-09-08
CA2657312A1 (en) 2007-11-08
CN101472923A (zh) 2009-07-01
NZ572741A (en) 2010-07-30
US8022207B2 (en) 2011-09-20
DE602007011601D1 (de) 2011-02-10
RU2008147002A (ru) 2010-06-10
KR20080112343A (ko) 2008-12-24
EP2022792A4 (de) 2009-11-11
TW200803903A (en) 2008-01-16

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