NO20092770L - Nye aminopyrimidinderivater som PLK1-inhibitorer - Google Patents

Nye aminopyrimidinderivater som PLK1-inhibitorer

Info

Publication number
NO20092770L
NO20092770L NO20092770A NO20092770A NO20092770L NO 20092770 L NO20092770 L NO 20092770L NO 20092770 A NO20092770 A NO 20092770A NO 20092770 A NO20092770 A NO 20092770A NO 20092770 L NO20092770 L NO 20092770L
Authority
NO
Norway
Prior art keywords
lower alkyl
alkyl group
group
substituted
hydrogen atom
Prior art date
Application number
NO20092770A
Other languages
English (en)
Norwegian (no)
Inventor
Morihiro Mitsuya
Takashi Hhashihayata
Mikako Kawamura
Yoshiyuki Satoh
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of NO20092770L publication Critical patent/NO20092770L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO20092770A 2006-12-28 2009-07-27 Nye aminopyrimidinderivater som PLK1-inhibitorer NO20092770L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2006356575 2006-12-28
JP2007265783 2007-10-11
PCT/JP2007/075224 WO2008081910A1 (fr) 2006-12-28 2007-12-20 Nouveaux dérivés d'aminopyrimidine comme inhibiteurs de plk1

Publications (1)

Publication Number Publication Date
NO20092770L true NO20092770L (no) 2009-09-25

Family

ID=39588592

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092770A NO20092770L (no) 2006-12-28 2009-07-27 Nye aminopyrimidinderivater som PLK1-inhibitorer

Country Status (24)

Country Link
US (1) US7977336B2 (fr)
EP (2) EP2114942B1 (fr)
JP (1) JPWO2008081914A1 (fr)
KR (1) KR101481388B1 (fr)
CN (1) CN101573361B (fr)
AR (1) AR064619A1 (fr)
AU (1) AU2007340530B2 (fr)
BR (1) BRPI0718966B8 (fr)
CA (1) CA2668738A1 (fr)
CL (1) CL2007003758A1 (fr)
CO (1) CO6190523A2 (fr)
CR (1) CR10784A (fr)
EC (1) ECSP099324A (fr)
GT (1) GT200900124A (fr)
IL (1) IL198675A0 (fr)
MA (1) MA31109B1 (fr)
MX (1) MX2009004920A (fr)
NO (1) NO20092770L (fr)
NZ (1) NZ577273A (fr)
PE (1) PE20081845A1 (fr)
RU (1) RU2458062C2 (fr)
SV (1) SV2009003258A (fr)
TW (1) TW200835485A (fr)
WO (2) WO2008081910A1 (fr)

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JP4489132B2 (ja) * 2008-08-22 2010-06-23 株式会社東芝 磁気記録媒体の製造方法
GB0906472D0 (en) 2009-04-15 2009-05-20 Astex Therapeutics Ltd New compounds
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US8445674B2 (en) 2009-10-21 2013-05-21 Hoffmann-La Roche Inc Heterocyclyl compounds
JP5641664B2 (ja) 2009-10-30 2014-12-17 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ イミダゾ［１，２−ｂ］ピリダジン誘導体およびＰＤＥ１０阻害剤としてのそれらの使用
UY33213A (es) 2010-02-18 2011-09-30 Almirall Sa Derivados de pirazol como inhibidores de jak
AR080754A1 (es) 2010-03-09 2012-05-09 Janssen Pharmaceutica Nv Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
EP2463289A1 (fr) 2010-11-26 2012-06-13 Almirall, S.A. Dérivés imidazo[1,2-b]pyridazine en tant qu'inhibiteur JAK
BR112013033375B1 (pt) 2011-06-27 2022-05-10 Janssen Pharmaceutica N.V Derivados de 1-aril-4-metil-[1,2,4]triazolo[4,3-a]quinoxa-lina, seu uso, composição farmacêutica que os compreende, processo de preparação dos mesmos, solução estéril e composto intermediário
EP2554544A1 (fr) 2011-08-01 2013-02-06 Almirall, S.A. Dérivés de pyridin-2(1h)-one en tant qu'inhibiteurs de JAK
EP2771337B1 (fr) 2011-09-27 2017-08-02 Novartis AG 3-(pyrimidin-4-yl)-oxazolidin-2-ones comme inhibiteurs d'idh mutante
AU2013283426B2 (en) 2012-06-26 2018-02-22 Janssen Pharmaceutica Nv Combinations comprising PDE 2 inhibitors such as 1-aryl-4-methyl- [1,2,4] triazolo [4,3-a] quinoxaline compounds and PDE 10 inhibitors for use in the treatment of neurological or metabolic disorders
WO2014009305A1 (fr) 2012-07-09 2014-01-16 Janssen Pharmaceutica Nv Inhibiteurs de l'enzyme phosphodiestérase 10
JP6324381B2 (ja) 2012-07-31 2018-05-16 クラウン バイオサイエンス インコーポレイテッド（タイカン） 抗ｅｇｆｒ薬物による処置のための非小細胞肺癌患者を同定するための組織学的マーカー
WO2014046617A1 (fr) * 2012-09-19 2014-03-27 Agency For Science, Technology And Research Compositions et méthodes de traitement du cancer
JP6559228B2 (ja) 2014-09-17 2019-08-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 肥満症及び糖尿病の治療に有用なテトラヒドロイソキノリン誘導体及び医薬組成物
WO2018191171A1 (fr) * 2017-04-10 2018-10-18 City Of Hope Inhibiteurs de gamma p38 et leur procédé d'utilisation
CN114269742B (zh) * 2019-07-10 2024-07-16 常州千红生化制药股份有限公司 作为治疗剂的4-(咪唑并[1,2-a]吡啶-3-基)-N-(吡啶基)嘧啶-2-胺的衍生物
AU2020318710B2 (en) * 2019-07-24 2025-11-20 Merck Patent Gmbh 4-(imidazo[1,2-a]pyridin-3-yl) -pyrimidine derivatives
CN112592318B (zh) * 2020-12-12 2022-05-03 贵州医科大学 2-(4-甲氨酰基)苯胺基-4-氨基嘧啶衍生物及应用
EP4597104A1 (fr) 2022-09-29 2025-08-06 Japanese Foundation For Cancer Research Procédé de criblage de médicament basé sur un concept de découverte de médicament d'inhibition de la prolifération des cellules cancéreuses induite par l'interruption de la régulation chromosomique due à l'activation de la kinase plk1
CN119318874B (zh) * 2024-12-18 2025-04-15 淄博凯美可工贸有限公司 一种节能型复合脱硫剂的制备方法

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Also Published As

Publication number Publication date
CN101573361A (zh) 2009-11-04
US7977336B2 (en) 2011-07-12
ECSP099324A (es) 2009-06-30
IL198675A0 (en) 2010-02-17
EP2114942A4 (fr) 2010-09-08
JPWO2008081914A1 (ja) 2010-04-30
CO6190523A2 (es) 2010-08-19
SV2009003258A (es) 2010-08-23
AU2007340530A1 (en) 2008-07-10
WO2008081914A1 (fr) 2008-07-10
TW200835485A (en) 2008-09-01
CN101573361B (zh) 2012-05-30
MX2009004920A (es) 2009-05-21
PE20081845A1 (es) 2008-12-27
US20080305081A1 (en) 2008-12-11
RU2009128966A (ru) 2011-02-10
MA31109B1 (fr) 2010-01-04
CL2007003758A1 (es) 2008-07-04
EP2114942A1 (fr) 2009-11-11
CA2668738A1 (fr) 2008-07-10
AU2007340530B2 (en) 2012-09-13
EP2114942B1 (fr) 2012-10-31
BRPI0718966B8 (pt) 2021-05-25
BRPI0718966B1 (pt) 2020-11-17
GT200900124A (es) 2010-11-03
CR10784A (es) 2009-09-16
KR20090092822A (ko) 2009-09-01
EP2116543A4 (fr) 2010-09-08
KR101481388B1 (ko) 2015-01-12
EP2116543A1 (fr) 2009-11-11
BRPI0718966A2 (pt) 2014-01-07
NZ577273A (en) 2011-03-31
AR064619A1 (es) 2009-04-15
WO2008081910A1 (fr) 2008-07-10
RU2458062C2 (ru) 2012-08-10

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