NO841993L - Immunologiske metoder for paavisning av maligne celler med metastatisk celleaktivitet, samt preparater for utfoerelse av slike metoder - Google Patents

Immunologiske metoder for paavisning av maligne celler med metastatisk celleaktivitet, samt preparater for utfoerelse av slike metoder

Info

Publication number
NO841993L
NO841993L NO841993A NO841993A NO841993L NO 841993 L NO841993 L NO 841993L NO 841993 A NO841993 A NO 841993A NO 841993 A NO841993 A NO 841993A NO 841993 L NO841993 L NO 841993L
Authority
NO
Norway
Prior art keywords
type
antibody
antigen
collagenase
enzyme
Prior art date
Application number
NO841993A
Other languages
English (en)
Norwegian (no)
Inventor
Karl Tryggvason
Lance Allen Liotta
Original Assignee
Karl Tryggvason
Liotta Lance A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karl Tryggvason, Liotta Lance A filed Critical Karl Tryggvason
Publication of NO841993L publication Critical patent/NO841993L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
NO841993A 1983-05-19 1984-05-18 Immunologiske metoder for paavisning av maligne celler med metastatisk celleaktivitet, samt preparater for utfoerelse av slike metoder NO841993L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/496,230 US4677058A (en) 1983-05-19 1983-05-19 Detecting malignant cells with monoclonal antibodies specific to type IV collagenase enzyme

Publications (1)

Publication Number Publication Date
NO841993L true NO841993L (no) 1984-11-20

Family

ID=23971775

Family Applications (1)

Application Number Title Priority Date Filing Date
NO841993A NO841993L (no) 1983-05-19 1984-05-18 Immunologiske metoder for paavisning av maligne celler med metastatisk celleaktivitet, samt preparater for utfoerelse av slike metoder

Country Status (26)

Country Link
US (1) US4677058A (fr)
JP (1) JPS602187A (fr)
AU (1) AU2808784A (fr)
BE (1) BE899663A (fr)
CA (1) CA1230052A (fr)
CH (1) CH668838A5 (fr)
DD (1) DD251208A5 (fr)
DE (1) DE3418625A1 (fr)
DK (1) DK243184A (fr)
ES (1) ES8605904A1 (fr)
FI (1) FI841897L (fr)
FR (1) FR2546302B1 (fr)
GB (1) GB2142030B (fr)
HU (1) HU195004B (fr)
IL (1) IL71802A0 (fr)
IT (1) IT1175842B (fr)
LU (1) LU85366A1 (fr)
NL (1) NL8401616A (fr)
NO (1) NO841993L (fr)
NZ (1) NZ208108A (fr)
PL (1) PL247745A1 (fr)
PT (1) PT78610B (fr)
RO (1) RO92427A (fr)
SE (1) SE8402703L (fr)
YU (1) YU86984A (fr)
ZA (1) ZA843539B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294172B1 (en) 1983-08-12 2001-09-25 Dade Behring Marburg Gmbh Monoclonal antibodies with specificity for membrane-associated antigens
US4859581A (en) * 1986-03-10 1989-08-22 Board Of Regents, The University Of Texas System Endoglycosidase assay
US4923818A (en) * 1987-09-04 1990-05-08 Washington University DNA clone of human type IV collagenase
GB2209526B (en) * 1987-09-04 1992-06-03 Univ Washington Dna clone of human type iv collagenase
US4876332A (en) * 1987-10-08 1989-10-24 Regents Of The Univeristy Of Minnesota Polypeptides with type IV collagen activity
US5280106A (en) * 1988-05-20 1994-01-18 Liotta Lance A Matrix metalloproteinase peptides: role in diagnosis and therapy
US5030555A (en) * 1988-09-12 1991-07-09 University Of Florida Membrane-strip reagent serodiagnostic apparatus and method
DE3909799A1 (de) * 1989-03-24 1990-09-27 Behringwerke Ag Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung
US4992537A (en) * 1989-05-15 1991-02-12 Washington University cDNA encoding 92-kDA type IV collagenase
ES2164634T3 (es) * 1989-10-18 2002-03-01 Us Health Produccion y uso de proteina nm23-h2 humana y anticuerpos previstos a tal efecto.
WO1991011714A1 (fr) * 1990-01-26 1991-08-08 The United States Of America, Represented By The Secretary, United States Department Of Commerce Procede de mesure quantitative de collagenase
WO1992020820A1 (fr) * 1991-05-15 1992-11-26 Vanderbilt University Methode de determination du potentiel metastatique des cellules tumorales
US5324634A (en) * 1992-03-31 1994-06-28 The Research Foundation Of State University Of New York Diagnostic tests measuring gelatinase/inhibitor complexes for detection of aggressive and metastatic cancer
JP2673929B2 (ja) * 1993-04-12 1997-11-05 富士薬品工業株式会社 ヒト間質型コラゲナーゼと阻害剤との複合体の免疫学的定量法および臨床診断への応用
EP1789195B1 (fr) * 2004-08-26 2010-10-27 Life Technologies Corporation Distributeurs à électromouillage et procédés associés

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE343949B (fr) * 1966-06-02 1972-03-20 Pharmacia Ab
DE2363854C3 (de) * 1973-12-21 1980-01-03 Behringwerke Ag, 3550 Marburg Substrat zur Proteinasebestimmung sowie dessen Herstellung
US4201763A (en) * 1975-10-09 1980-05-06 Bio-Rad Laboratories, Inc. Solid phase immunofluorescent assay method
AT392004B (de) * 1981-10-27 1991-01-10 Hybritech Inc Verfahren zur herstellung eines monoklonalen antikoerpers gegen tumor-assoziiertes antigen und dessen verwendung
US4424278A (en) * 1981-11-16 1984-01-03 Research Corporation Cancer detection procedure using an acyl carrier protein
US4443367A (en) * 1982-04-08 1984-04-17 Monsanto Company Peptide and peptolide substrates for mammalian collagenase

Also Published As

Publication number Publication date
GB2142030B (en) 1987-02-04
IT8420998A1 (it) 1985-11-18
CH668838A5 (de) 1989-01-31
GB8411959D0 (en) 1984-06-13
JPS602187A (ja) 1985-01-08
FI841897A0 (fi) 1984-05-11
ES8605904A1 (es) 1986-04-01
DK243184D0 (da) 1984-05-17
PT78610B (en) 1986-07-15
HU195004B (en) 1988-03-28
IT8420998A0 (it) 1984-05-18
BE899663A (fr) 1984-08-31
FI841897A7 (fi) 1984-11-20
PL247745A1 (en) 1985-08-27
ZA843539B (en) 1985-07-31
DK243184A (da) 1984-11-20
FR2546302B1 (fr) 1988-03-04
RO92427A (fr) 1987-09-30
FR2546302A1 (fr) 1984-11-23
YU86984A (en) 1991-01-28
US4677058A (en) 1987-06-30
AU2808784A (en) 1984-11-22
SE8402703D0 (sv) 1984-05-18
FI841897L (fi) 1984-11-20
LU85366A1 (fr) 1984-11-19
IL71802A0 (en) 1984-09-30
CA1230052A (fr) 1987-12-08
DE3418625A1 (de) 1984-11-22
GB2142030A (en) 1985-01-09
SE8402703L (sv) 1984-11-20
NZ208108A (en) 1988-04-29
PT78610A (en) 1984-06-01
IT1175842B (it) 1987-07-15
DD251208A5 (de) 1987-11-04
ES532597A0 (es) 1986-04-01
NL8401616A (nl) 1984-12-17
HUT34261A (en) 1985-02-28

Similar Documents

Publication Publication Date Title
Zamarron et al. Monoclonal antibodies specific for a conformationally altered state of fibrinogen
US5912158A (en) Prostate specific antigen (PSA)-proteinase inhibitor complexes
US4894326A (en) Monoclonal antibody defining oncofetal structure of fibronectin
Schuppan et al. Radioimmunoassay for the carboxy-terminal cross-linking domain of type IV (basement membrane) procollagen in body fluids. Characterization and application to collagen type IV metabolism in fibrotic liver disease.
US4677058A (en) Detecting malignant cells with monoclonal antibodies specific to type IV collagenase enzyme
ES2328306T3 (es) Anticuerpo monospecifico reactivo con friginogeno y fibrinopeptido b.
EP0421392A1 (fr) Anticorps monoclonal contre le hCG-bêta à noyau, sa production et son utilisation
JP2012082210A (ja) Ａｄａｍｔｓ１３活性検定用抗体及び活性検定方法
US4816400A (en) Basement membrane collagen degrading enzyme and method of purifying same
KR910008637B1 (ko) 심근 미오신 중사슬에 대한 단일클론항체
KR910002957B1 (ko) 췌장의 α-아밀라제를 정량하는 방법 및 시약
US4808528A (en) Antibody composition for the detection of malignant cells with metastatic cell activity
Jemmerson et al. Convenient selection of monoclonal antibodies to isoenzymes of placental alkaline phosphatase using the catalytic activity of the antigen in enzyme-antigen immunoassay
Chinni et al. Cathepsin D antigenic epitopes identified by the humoral responses of ovarian cancer patients
JP5840274B2 (ja) ストロムライシン１と特異的に反応するモノクローナル抗体
Chao et al. Characterization of monoclonal and polyclonal antibodies to human tissue kallikrein.
US20080305499A1 (en) Anti-Synoviolin Antibody
JP2005154389A (ja) Ｃｄ４４の形態を識別する抗体
ITPD20000192A1 (it) Anticorpi policlonali
Kim et al. Characterization of a monoclonal antibody that specifically inhibits pullulanase activity of Bacillus circulans amylase-pullulanase enzyme
WO1996024065A1 (fr) Procedes de detection de procathepsines et leurs emplois
JPH05317086A (ja) カンジダ・アルビカンスの抗菌糸型抗体及び抗酵母型抗体
JPH09500965A (ja) 膀胱癌の浸潤性の測定方法
JPH0493659A (ja) ヒトα↓１―アンチキモトリプシンの測定方法
JPS63158463A (ja) ヒト膵型アミラ−ゼに対するモノクロ−ナル抗体及びその製造方法ならびにそれを用いるヒト膵型アミラ−ゼの定量方法