NO885386L - Bisfenylalkylpiperzin-derivater, en fremgangsmaate ved fremstilling og et farmasoeytisk preparat. - Google Patents

Bisfenylalkylpiperzin-derivater, en fremgangsmaate ved fremstilling og et farmasoeytisk preparat.

Info

Publication number: NO885386L
Authority: NO; Norway
Prior art keywords: preparation; pct; bisphenylalkyl; piperzine; derivatives
Prior art date: 1987-04-02

Application number

NO885386A

Other languages

English (en)

Other versions

NO885386D0 (no

NO172640C (no

NO172640B (no

Inventor

Tomas Fex

Knut Gunnar Olsson

Aina Lisbeth Abramo

Erik Gunnar Christensson

Thorbjoern Erik Lundstedt

Original Assignee

Leo Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-04-02

Filing date

1988-12-02

Publication date

1988-12-02

1988-12-02 Application filed by Leo Ab filed Critical Leo Ab

1988-12-02 Publication of NO885386L publication Critical patent/NO885386L/no

1988-12-02 Publication of NO885386D0 publication Critical patent/NO885386D0/no

1993-05-10 Publication of NO172640B publication Critical patent/NO172640B/no

1993-08-18 Publication of NO172640C publication Critical patent/NO172640C/no

Links

GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical class C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
208000019901 Anxiety disease Diseases 0.000 abstract 1
208000028017 Psychotic disease Diseases 0.000 abstract 1
230000036506 anxiety Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000020016 psychiatric disease Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
General Health & Medical Sciences (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO885386A 1987-04-02 1988-12-02 Analogifremgangsmaate ved fremstilling av terapeutisk aktive piperazinderivater NO172640C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE8701375A SE8701375D0 (sv)	1987-04-02	1987-04-02	Novel pyridyl- and pyrimidyl derivatives
PCT/SE1988/000144 WO1988007528A1 (en)	1987-04-02	1988-03-25	Bisphenylalkylpiperazine derivatives, a method of their preparation and a pharmaceutical preparation

Publications (4)

Publication Number	Publication Date
NO885386L true NO885386L (no)	1988-12-02
NO885386D0 NO885386D0 (no)	1988-12-02
NO172640B NO172640B (no)	1993-05-10
NO172640C NO172640C (no)	1993-08-18

Family

ID=20368077

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO885386A NO172640C (no)	1987-04-02	1988-12-02	Analogifremgangsmaate ved fremstilling av terapeutisk aktive piperazinderivater

Country Status (18)

Country	Link
US (1)	US4937245A (no)
EP (1)	EP0308476B1 (no)
JP (1)	JPH0819104B2 (no)
KR (1)	KR920003062B1 (no)
AT (1)	ATE85334T1 (no)
AU (1)	AU611147B2 (no)
CA (1)	CA1321997C (no)
DE (1)	DE3878111T2 (no)
DK (1)	DK161313C (no)
ES (1)	ES2006619A6 (no)
FI (1)	FI92320C (no)
HU (1)	HU201051B (no)
IE (1)	IE61165B1 (no)
IL (1)	IL85932A (no)
NO (1)	NO172640C (no)
NZ (1)	NZ224005A (no)
SE (1)	SE8701375D0 (no)
WO (1)	WO1988007528A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8701375D0 (sv) *	1987-04-02	1987-04-02	Leo Ab	Novel pyridyl- and pyrimidyl derivatives
US5219855A (en) *	1988-01-29	1993-06-15	Mitsubishi Kasei Corporation	Anxiolytic drug
JP2664238B2 (ja) *	1989-03-01	1997-10-15	日清製粉株式会社	ニコチン酸またはそのエステル誘導体
US4994460A (en) *	1989-06-01	1991-02-19	Bristol-Myers Squibb Co.	Agents for treatment of brain ischemia
SE9201239D0 (sv) *	1992-04-21	1992-04-21	Kabi Pharmacia Ab	Agents for treating substance abuse disorders
EP0580465A1 (fr) *	1992-06-25	1994-01-26	Sanofi	Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés
JPH0665203A (ja) *	1992-06-25	1994-03-08	Elf Sanofi	ピペラジンのヘテロ環誘導体
SE9201956D0 (sv) *	1992-06-25	1992-06-25	Kabi Pharmacia Ab	Novel nicotinicacid esters
SE9202265D0 (sv) *	1992-07-31	1992-07-31	Kabi Pharmacia Ab	Novel- pyridyl and pyrimidylpiperazine derivatives
DK139593D0 (da) *	1993-12-16	1993-12-16	Lundbeck & Co As H	Compounds
AU744539B2 (en)	1997-10-27	2002-02-28	Neurosearch A/S	Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors
US6632823B1 (en) *	1997-12-22	2003-10-14	Merck & Co., Inc.	Substituted pyridine compounds useful as modulators of acetylcholine receptors
WO2000061556A1 (en)	1999-04-09	2000-10-19	Meiji Seika Kaisha, Ltd.	Nitrogen-containing heterocyclic compounds and benamide compounds and drugs containing the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2958694A (en) *	1959-06-22	1960-11-01	Janssen Paul Adriaan Jan	1-(aroylalkyl)-4-(2'-pyridyl) piperazines
US2979508A (en) *	1959-10-12	1961-04-11	Paul A J Janssen	Heterocyclic derivatives of 1-phenyl-omega-(piperazine) alkanols
US2985657A (en) *	1959-10-12	1961-05-23	Paul A J Janssen	1-(aroylalkyl)-4-heterocyclylpiperazines
JPS6081167A (ja) *	1983-10-11	1985-05-09	Sumitomo Chem Co Ltd	フエニルアセトン誘導体およびその製造法
US4605655A (en) *	1984-03-06	1986-08-12	Bristol-Myers Company	Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
JPS6175A (ja) *	1984-03-06	1986-01-06	ブリストル−マイア−ズ　コムパニ−	神経弛緩剤、１‐フルオロフェニルブチル‐４‐（５‐ハロ‐２‐ピリミジニル）ピペラジン誘導体
GB8603120D0 (en) *	1986-02-07	1986-03-12	Pfizer Ltd	Anti-dysrhythmia agents
JPS63146872A (ja) *	1986-07-08	1988-06-18	Yoshitomi Pharmaceut Ind Ltd	ピリミジニルピペラジン化合物
US4766215A (en) *	1987-02-27	1988-08-23	American Home Products Corporation	Histamine H1 -receptor antagonists
SE8701375D0 (sv) *	1987-04-02	1987-04-02	Leo Ab	Novel pyridyl- and pyrimidyl derivatives

1987
- 1987-04-02 SE SE8701375A patent/SE8701375D0/xx unknown
1988
- 1988-03-23 IE IE86988A patent/IE61165B1/en not_active IP Right Cessation
- 1988-03-24 NZ NZ224005A patent/NZ224005A/en unknown
- 1988-03-25 WO PCT/SE1988/000144 patent/WO1988007528A1/en not_active Ceased
- 1988-03-25 AT AT88903427T patent/ATE85334T1/de not_active IP Right Cessation
- 1988-03-25 HU HU882510A patent/HU201051B/hu not_active IP Right Cessation
- 1988-03-25 JP JP63503107A patent/JPH0819104B2/ja not_active Expired - Fee Related
- 1988-03-25 US US07/282,130 patent/US4937245A/en not_active Expired - Lifetime
- 1988-03-25 EP EP88903427A patent/EP0308476B1/en not_active Expired - Lifetime
- 1988-03-25 DE DE8888903427T patent/DE3878111T2/de not_active Expired - Fee Related
- 1988-03-25 AU AU15796/88A patent/AU611147B2/en not_active Ceased
- 1988-03-30 ES ES8800998A patent/ES2006619A6/es not_active Expired
- 1988-03-30 IL IL85932A patent/IL85932A/xx not_active IP Right Cessation
- 1988-03-31 CA CA000563050A patent/CA1321997C/en not_active Expired - Fee Related
- 1988-04-02 KR KR1019880003734A patent/KR920003062B1/ko not_active Expired
- 1988-11-30 FI FI885560A patent/FI92320C/fi not_active IP Right Cessation
- 1988-12-01 DK DK671588A patent/DK161313C/da not_active IP Right Cessation
- 1988-12-02 NO NO885386A patent/NO172640C/no unknown

Also Published As

Publication number	Publication date
EP0308476B1 (en)	1993-02-03
IE61165B1 (en)	1994-10-05
DK161313B (da)	1991-06-24
CA1321997C (en)	1993-09-07
WO1988007528A1 (en)	1988-10-06
DE3878111D1 (de)	1993-03-18
AU611147B2 (en)	1991-06-06
FI92320C (fi)	1994-10-25
JPH01502832A (ja)	1989-09-28
HU201051B (en)	1990-09-28
FI885560A0 (fi)	1988-11-30
SE8701375D0 (sv)	1987-04-02
KR880012586A (ko)	1988-11-28
KR920003062B1 (ko)	1992-04-13
IL85932A (en)	1993-05-13
NZ224005A (en)	1991-03-26
IL85932A0 (en)	1988-09-30
FI885560A7 (fi)	1988-11-30
FI92320B (fi)	1994-07-15
DK671588A (da)	1988-12-01
AU1579688A (en)	1988-11-02
NO885386D0 (no)	1988-12-02
HUT50325A (en)	1990-01-29
DK161313C (da)	1991-12-30
NO172640C (no)	1993-08-18
DE3878111T2 (de)	1993-07-01
EP0308476A1 (en)	1989-03-29
NO172640B (no)	1993-05-10
ATE85334T1 (de)	1993-02-15
ES2006619A6 (es)	1989-05-01
DK671588D0 (da)	1988-12-01
IE880869L (en)	1988-10-02
JPH0819104B2 (ja)	1996-02-28
US4937245A (en)	1990-06-26

Publication	Publication Date	Title
HUT68357A (en)	1995-06-28	Heterocyclic-cyclic-amine derivatives, pharmaceutical compositions containing them and process for their production
NO885386D0 (no)	1988-12-02	Bisfenylalkylpiperzin-derivater, en fremgangsmaate ved fremstilling og et farmasoeytisk preparat.
NO933200L (no)	1994-03-10	Substituerte cykloheksanderivater, fremgangsmåte til fremstilling derav og anvendelsen av forbindelsene til behandling av sykdommer
FI884553A0 (fi)	1988-10-04	Analogiamenetelmä terapeuttisesti käyttökelpoisten 9-aminotetrahydroakridiinijohdannaisten valmistamiseksi
DK213087D0 (da)	1987-04-27	1,4-disubstituerede piperazinderivater og farmaceutisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse
DK0450420T3 (da)	1995-02-20	Heterocyclisk substituerede dihydropyridiner, fremgangsmåde til deres fremstilling og deres anvendelse i lægemidler
IL79910A (en)	1990-02-09	5,7-dihydro-6-(thi)oxopyrrolo(2,3-f)benzimidazole,-benzothiazole and-benzoxazoles,6-imines thereof,their preparation and pharmaceutical compositions containing them
DK0401093T3 (da)	1995-07-10	Hidtil ukendte pyrrolidonderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende disse
NO952559D0 (no)	1995-06-26	N-acyl-pyrrolidiner og medikamenter for behandling eller prevensjon av cholecystokinin- og gastrin-relaterte mangler
ZA88639B (en)	1988-10-26	Substituted 3-phenyl-7h-thiazolo(3,2-b)(1,2,4)triazin-7-ones,a process for the preparation thereof,medicaments containing same and the use thereof,and also some intermediates formed in the preparation of the compounds mentioned
ES2036219T3 (es)	1993-05-16	2,2; 6,6-dietilen-3-oxo-17alfa-pren-4-en-21,17alfa-carbolactonas, procedimiento para su preparacion y preparados farmaceuticos que las contienen.
ZA872863B (en)	1987-10-13	1,4-dihydropyridine derivatives,process for their preparation and medicaments containing these compounds
DE69419083D1 (de)	1999-07-22	Salmycine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel