NO964745L - Fremgangsmåte for fremstilling av et aspartamforbindelsesderivat anvendelig som sötningsmiddel - Google Patents

Fremgangsmåte for fremstilling av et aspartamforbindelsesderivat anvendelig som sötningsmiddel

Info

Publication number
NO964745L
NO964745L NO964745A NO964745A NO964745L NO 964745 L NO964745 L NO 964745L NO 964745 A NO964745 A NO 964745A NO 964745 A NO964745 A NO 964745A NO 964745 L NO964745 L NO 964745L
Authority
NO
Norway
Prior art keywords
preparing
sweetener
aspartame
compound derivative
derivative useful
Prior art date
Application number
NO964745A
Other languages
English (en)
Other versions
NO964745D0 (no
NO313832B1 (no
Inventor
Claude Nofre
Jean-Marie Tinti
Original Assignee
Claude Nofre
Tinti Jean Marie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Claude Nofre, Tinti Jean Marie filed Critical Claude Nofre
Publication of NO964745D0 publication Critical patent/NO964745D0/no
Publication of NO964745L publication Critical patent/NO964745L/no
Publication of NO313832B1 publication Critical patent/NO313832B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
NO19964745A 1994-05-09 1996-11-08 Forbedret fremgangsmÕte for fremstilling av et aspartamforbindelsesderivat anvendelig som sötningsmiddel NO313832B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9405674A FR2719590B1 (fr) 1994-05-09 1994-05-09 Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
PCT/FR1995/000589 WO1995030689A1 (fr) 1994-05-09 1995-05-05 Procede perfectionne de preparation d'un compose derive de l'aspartame utile comme agent edulcorant

Publications (3)

Publication Number Publication Date
NO964745D0 NO964745D0 (no) 1996-11-08
NO964745L true NO964745L (no) 1996-11-08
NO313832B1 NO313832B1 (no) 2002-12-09

Family

ID=9463024

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19964745A NO313832B1 (no) 1994-05-09 1996-11-08 Forbedret fremgangsmÕte for fremstilling av et aspartamforbindelsesderivat anvendelig som sötningsmiddel

Country Status (29)

Country Link
US (1) US5510508A (no)
EP (1) EP0759031B1 (no)
JP (1) JP3303921B2 (no)
KR (1) KR100304320B1 (no)
CN (1) CN1114615C (no)
AT (1) ATE169636T1 (no)
AU (1) AU681523B2 (no)
BG (1) BG62813B1 (no)
BR (1) BR9507635A (no)
CA (1) CA2187901C (no)
CZ (1) CZ285612B6 (no)
DE (1) DE69504059T2 (no)
DK (1) DK0759031T3 (no)
EE (1) EE03402B1 (no)
ES (1) ES2122610T3 (no)
FI (1) FI114313B (no)
FR (1) FR2719590B1 (no)
GE (1) GEP19991647B (no)
HU (1) HU219829B (no)
MD (1) MD1175G2 (no)
NO (1) NO313832B1 (no)
NZ (1) NZ285777A (no)
OA (1) OA10334A (no)
PL (1) PL180471B1 (no)
RO (1) RO115732B1 (no)
RU (1) RU2138510C1 (no)
SK (1) SK280376B6 (no)
UA (1) UA41403C2 (no)
WO (1) WO1995030689A1 (no)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2719591B1 (fr) * 1994-05-09 1996-07-26 Claude Nofre Nouveau composé utile comme agent édulcorant, son procédé de préparation.
FR2744454B1 (fr) * 1996-02-07 1998-04-24 Nofre Claude Acide n-(3,3-dimethylbutyl)-l-aspartyl-d-alpha- aminoalcanoique n-(s)-1-phenyl-1-alcanamide utile comme agent edulcorant
US5728862A (en) * 1997-01-29 1998-03-17 The Nutrasweet Company Method for preparing and purifying an N-alkylated aspartame derivative
US5770775A (en) * 1997-02-10 1998-06-23 The Nutrasweet Company Method for preparing 3,3-dimethylbutyraldehyde
US5973209A (en) * 1997-07-11 1999-10-26 The Nutrasweet Company Method for preparing 3, 3-dimethybutyraldehyde
US6291004B1 (en) 1997-09-11 2001-09-18 The Nutrasweet Company Basic salts of n-[n-(3,3-dimethylbutyl)-l-α-aspartyl]-l-phenylalanine 1-methyl ester
US6146680A (en) * 1997-09-11 2000-11-14 The Nutrasweet Company Metal complexes of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US6180156B1 (en) 1997-09-11 2001-01-30 The Nutrasweet Company Acid salts of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US6129942A (en) * 1997-09-11 2000-10-10 The Nutrasweet Company Sweetener salts of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
JPH1180108A (ja) * 1997-09-12 1999-03-26 Ajinomoto Co Inc 甘味料の精製法
JPH11130794A (ja) * 1997-10-23 1999-05-18 Ajinomoto Co Inc アスパルテーム誘導体の精製方法
JPH11171895A (ja) 1997-12-11 1999-06-29 Ajinomoto Co Inc アスパルテームとアスパルテーム誘導体の分離精製方法
JPH11169133A (ja) * 1997-12-15 1999-06-29 Ajinomoto Co Inc アスパルテーム及びアスパルテーム誘導体を含有する甘味料組成物
JPH11169132A (ja) * 1997-12-15 1999-06-29 Ajinomoto Co Inc アスパルテームとアスパルテーム誘導体の混晶及びその製造方法
AR014129A1 (es) * 1997-12-17 2001-02-07 Nutrasweet Co Bebida que comprende fundamentalmente un ester n-[n-(3,3-dimetilbutil)-l- alfa-aspartil]-l-fenilamina 1 - metilico, bebida sin alcohol carbonatada,bebida de jugo, bebida envasada caliente y bebida deportiva de bajas calorias.
CO5040056A1 (es) * 1997-12-17 2001-05-29 Nutrasweet Co Composiciones edulcorantes de mesa que comprenden edulcorant e de potencia extremadamente alta
AU1936499A (en) * 1997-12-17 1999-07-05 Nutrasweet Company, The Use of n-{n-(3,3-dimethylbutyl)-l-alpha-aspartyl}-l-phenylalanine 1-methyl esterin dairy and dairy analogue products
JP2000026496A (ja) * 1998-05-08 2000-01-25 Ajinomoto Co Inc 新規アスパルテーム誘導体結晶及びその製造法
JP3643921B2 (ja) * 1998-05-08 2005-04-27 味の素株式会社 新規甘味料組成物
JPH11322788A (ja) * 1998-05-08 1999-11-24 Ajinomoto Co Inc 新規アスパルテーム誘導体結晶及びその製造方法
JP3643922B2 (ja) * 1998-05-08 2005-04-27 味の素株式会社 甘味料組成物
US5905175A (en) * 1998-05-20 1999-05-18 The Nutrasweet Company Synthesis and purification of 3,3-dimethylbutyraldehyde via oxidation of 1-chloro-3,3-dimethylbutane with dimethyl sulfoxide
US6692778B2 (en) 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
AU7822398A (en) * 1998-06-05 1999-12-20 Wm. Wrigley Jr. Company Method of controlling release of n-substituted derivatives of aspartame in chewing gum and gum produced thereby
EP1088829A4 (en) * 1998-06-26 2005-02-02 Ajinomoto Kk NEW ASPARTYL DIPETPID ESTER AND SWEETENING DERIVATIVES
US5977415A (en) * 1998-08-20 1999-11-02 The Nutrasweet Company Preparation of 3, 3-dimethylbutyraldehyde from a tert-butyl cation precursor, vinyl chloride and an acidic catalyst
NL1010063C2 (nl) * 1998-09-10 2000-03-13 Holland Sweetener Co Werkwijze voor de bereiding van neotaam.
US6214402B1 (en) * 1998-09-17 2001-04-10 The Nutrasweet Company Co-crystallization of sugar and n-[n-(3,3-dimethylbutyl)-l αaspartyl]-l-phenylalanine 1-methyl ester
US5994593A (en) * 1998-09-17 1999-11-30 The Nutrasweet Company Synthesis and purification of 3,3-dimethylbutyraldehyde via hydrolysis of 1,1-dichloro-3,3-dimethylbutane or 1-bromo-1-chloro-3,3-dimethylbutane
US6844465B2 (en) 1998-10-30 2005-01-18 Ajinomoto Co., Inc. Method for preparing highly stable crystals of aspartame derivative
BR9914838A (pt) * 1998-10-30 2001-08-14 Ajinomoto Kk Processo para preparar cristais altamente estáveis (cristais do tipo a) de éster metìlico de n-[n-(3,3-dimetilbutil)-l-alfa-aspartil]-l-fenilalanina
WO2000026234A1 (en) * 1998-10-30 2000-05-11 Ajinomoto Co., Inc. Crystallization processes for the formation of stable crystals of aspartame derivative
US6465677B1 (en) 1998-11-19 2002-10-15 The Nutrasweet Company Method for the preparation of N-neohexyl-α-aspartyl-L-phenylalanine methyl ester from imidazolidin-4-one intermediates
US6331646B1 (en) * 1998-11-20 2001-12-18 The Nutrasweet Co. Amorphous N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
AU1832500A (en) 1998-11-25 2000-06-19 Nutrasweet Company, The Purification of N-(N-(3,3-dimethylbutyl)-l-alpha-aspartyl)-l-phenylalanine 1-methyl ester via crystallization
EP1139776A1 (en) * 1998-12-18 2001-10-10 The NutraSweet Company N-[n-(3,3-dimethylbutyl)-l-alpha-aspartyl]-l-phenylalanine 1- methyl ester as a sweetener in chewing gum
US6077962A (en) * 1998-12-24 2000-06-20 The Nutrasweet Company N-3, 3-dimethylbutyl-L-aspartic acid and esters thereof, the process of preparing the same, and the process for preparing N-(N-(3,3-dimethylbutyl) -α L-aspartyl)-L- phenylalanine 1-methyl ester therefrom
US6048999A (en) * 1999-01-25 2000-04-11 The Nutrasweet Company N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester synergistic sweetener blends
US6180157B1 (en) 1999-02-18 2001-01-30 The Nutrasweet Company Process for preparing an N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester agglomerate
WO2000057725A1 (en) 1999-03-26 2000-10-05 The Nutrasweet Company PARTICLES OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER
RU2145869C1 (ru) * 1999-04-30 2000-02-27 Орещенко Андрей Владимирович Способ антимутагенного воздействия на организм
US6726922B1 (en) 1999-06-28 2004-04-27 Minu, L.L.C. Process and composition for temporarily suppressing pain
US6573409B1 (en) * 1999-07-02 2003-06-03 The Nutrasweet Company Process for the preparation of 3,3-dimethylbutanal
AU4459400A (en) 1999-07-28 2001-02-19 Nutrasweet Company, The A method for the purification of n-[n-(3,3-dimethylbutyl)-l-alpha-aspartyl]-l-phenylalanine 1-methyl ester
US6506434B1 (en) 1999-08-06 2003-01-14 The Nutrasweet Company Process for coating N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester onto a carrier
AU6238800A (en) * 1999-08-11 2001-03-05 Nutrasweet Company, The Confectionery food products sweetened with n-[n-(3,3-dimethylbutyl)-1-alpha-aspartyl]-l-phenylalanine methyl ester
CA2383137A1 (en) * 1999-09-07 2001-03-15 Ajinomoto Co., Inc. Method for producing aspartame derivative, method for purifying the same, crystals thereof and uses of the same
EP1219633A4 (en) * 1999-10-08 2004-10-20 Ajinomoto Kk PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, PRODUCTION OF NEW ASSOCIATED INTERMEDIATES AND PROCESS FOR PRODUCING INTERMEDIATE
US6627431B1 (en) 2000-05-12 2003-09-30 The Nutrasweet Company Chemoenzymatic synthesis of neotame
AU2001263267A1 (en) * 2000-05-18 2001-11-26 The Nutrasweet Company Synthesis of n-(n-(3,3-dimethylbutyl)-l-alpha-aspartyl)-l-phenylalanine 1-methylester using l-alpha-aspartyl-l-phenylalanine 1-methyl ester precursors
EP1403276B1 (en) * 2000-05-18 2005-11-16 The NutraSweet Company Synthesis of N-[N-(3,3-dimethylbutyl)-L-alpha-aspartyl]-L-phenylalanine 1-methyl ester using L-alpha-aspartyl-L-phenylalanine 1-methyl ester precursors
DE60108745T2 (de) * 2000-05-19 2005-07-07 The Nutrasweet Co., Chicago Herstellung von N-[N-(3,3-Dimethylbutyl)-L-α-aspartyl]-L-phenylalanin-1-methylester mittels Oxazolidinonderivate
US7326430B2 (en) * 2000-07-18 2008-02-05 The Nutrasweet Company Method of preparing liquid compositions for delivery of N-[N- (3,3-dimethylbutyl-L-α-aspartyl]-L-phenylalanine 1-methyl ester in food and beverage systems
WO2002065853A2 (en) * 2000-11-06 2002-08-29 The Nutrasweet Company Catalyst modification to enhance neotame production
WO2004101604A2 (en) 2003-05-06 2004-11-25 Nutrasweet Company SYNTHESIS OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER USING 3,3-DIMETHYLBUTYRALDEHYDE PRECURSORS
US20050196503A1 (en) * 2004-03-05 2005-09-08 Sunil Srivastava High-intensity sweetener-polyol compositions
US20060188629A1 (en) * 2005-01-21 2006-08-24 Greg Liesen Method for the purification of sucralose
WO2007064740A2 (en) * 2005-12-02 2007-06-07 The Coca-Cola Company Reduced calorie frozen beverage
CN101270092B (zh) * 2008-04-30 2010-12-08 厦门大学 一种合成纽甜的方法
US20100125146A1 (en) * 2008-11-19 2010-05-20 Johnson Matthey Public Limited Company Method for making pharmaceutical compounds
CN105131081A (zh) * 2015-09-08 2015-12-09 南京工业大学 一种廉价高效的纽甜制备方法
FR3102041B1 (fr) 2019-10-22 2025-02-14 Aroma Sens Edulcorant pour liquides de cigarette électronique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2533210A1 (fr) * 1982-09-17 1984-03-23 Lyon I Universite Claude Edulcorants de synthese
JPH07636B2 (ja) * 1984-12-17 1995-01-11 三井東圧化学株式会社 Ｎ−ホルミル−α−アスパルチルフエニルアラニンの製造法
FR2630304B1 (fr) * 1988-04-22 1990-08-31 Bernard Lyon I Universite Clau Derives n-hydrocarbones des acides aspartique et glutamique alpha-monoamides utiles comme agents edulcorants
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.

Also Published As

Publication number Publication date
WO1995030689A1 (fr) 1995-11-16
NO964745D0 (no) 1996-11-08
PL180471B1 (pl) 2001-02-28
CZ285612B6 (cs) 1999-09-15
ATE169636T1 (de) 1998-08-15
FR2719590A1 (fr) 1995-11-10
KR100304320B1 (ko) 2001-11-30
HU219829B (hu) 2001-08-28
FI964106A0 (fi) 1996-10-14
MX9605244A (es) 1997-09-30
JPH09512809A (ja) 1997-12-22
CN1114615C (zh) 2003-07-16
RU2138510C1 (ru) 1999-09-27
CZ329996A3 (en) 1997-02-12
AU2528595A (en) 1995-11-29
DK0759031T3 (da) 1999-05-17
EP0759031A1 (fr) 1997-02-26
MD1175G2 (ro) 2000-02-29
DE69504059T2 (de) 1999-02-25
PL317053A1 (en) 1997-03-03
GEP19991647B (en) 1999-06-14
CA2187901A1 (en) 1995-11-16
NZ285777A (en) 1997-04-24
OA10334A (fr) 1997-10-07
ES2122610T3 (es) 1998-12-16
CA2187901C (en) 2003-09-09
UA41403C2 (uk) 2001-09-17
US5510508A (en) 1996-04-23
MD1175F1 (en) 1999-03-31
DE69504059D1 (de) 1998-09-17
HUT75087A (en) 1997-04-28
EE9600179A (et) 1997-06-16
FI964106L (fi) 1996-10-14
FI114313B (fi) 2004-09-30
BR9507635A (pt) 1997-09-23
SK144996A3 (en) 1997-05-07
NO313832B1 (no) 2002-12-09
EE03402B1 (et) 2001-04-16
CN1147817A (zh) 1997-04-16
FR2719590B1 (fr) 1996-07-26
JP3303921B2 (ja) 2002-07-22
SK280376B6 (sk) 1999-12-10
RO115732B1 (ro) 2000-05-30
EP0759031B1 (fr) 1998-08-12
HK1012406A1 (en) 1999-07-30
BG100967A (en) 1998-01-30
BG62813B1 (bg) 2000-08-31
AU681523B2 (en) 1997-08-28
HU9602990D0 (en) 1997-01-28

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