NO975334D0 - Anvendelse av flavanolignaner for fremstilling av medikamenter med antiproliferativ aktivitet i uterus, ovarium og bryst - Google Patents
Anvendelse av flavanolignaner for fremstilling av medikamenter med antiproliferativ aktivitet i uterus, ovarium og brystInfo
- Publication number
- NO975334D0 NO975334D0 NO975334A NO975334A NO975334D0 NO 975334 D0 NO975334 D0 NO 975334D0 NO 975334 A NO975334 A NO 975334A NO 975334 A NO975334 A NO 975334A NO 975334 D0 NO975334 D0 NO 975334D0
- Authority
- NO
- Norway
- Prior art keywords
- silicristin
- silidianin
- mixtures
- effective amount
- therapeutically effective
- Prior art date
Links
- 230000001028 anti-proliverative effect Effects 0.000 title abstract 2
- 210000000481 breast Anatomy 0.000 title abstract 2
- 210000001672 ovary Anatomy 0.000 title abstract 2
- 210000004291 uterus Anatomy 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- SEBFKMXJBCUCAI-UHFFFAOYSA-N NSC 227190 Natural products C1=C(O)C(OC)=CC(C2C(OC3=CC=C(C=C3O2)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-UHFFFAOYSA-N 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- SEBFKMXJBCUCAI-HKTJVKLFSA-N silibinin Chemical compound C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC=C(C=C3O2)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-HKTJVKLFSA-N 0.000 abstract 4
- CYGIJEJDYJOUAN-UHFFFAOYSA-N Isosilychristin Natural products C1=C(O)C(OC)=CC(C2C3C=C(C4C(C3=O)(O)OCC42)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 CYGIJEJDYJOUAN-UHFFFAOYSA-N 0.000 abstract 3
- 229950004878 silicristin Drugs 0.000 abstract 3
- 229950004304 silidianin Drugs 0.000 abstract 3
- BMLIIPOXVWESJG-LMBCONBSSA-N silychristin Chemical compound C1=C(O)C(OC)=CC([C@H]2[C@@H](C3=C(C(=CC(=C3)[C@@H]3[C@H](C(=O)C4=C(O)C=C(O)C=C4O3)O)O)O2)CO)=C1 BMLIIPOXVWESJG-LMBCONBSSA-N 0.000 abstract 3
- BMLIIPOXVWESJG-UHFFFAOYSA-N silychristin A Natural products C1=C(O)C(OC)=CC(C2C(C3=C(C(=CC(=C3)C3C(C(=O)C4=C(O)C=C(O)C=C4O3)O)O)O2)CO)=C1 BMLIIPOXVWESJG-UHFFFAOYSA-N 0.000 abstract 3
- CYGIJEJDYJOUAN-JSGXPVSSSA-N silydianin Chemical compound C1=C(O)C(OC)=CC([C@H]2[C@H]3C=C([C@@H]4[C@@](C3=O)(O)OC[C@@H]42)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 CYGIJEJDYJOUAN-JSGXPVSSSA-N 0.000 abstract 3
- BVKQRAYKLBRNIK-UHFFFAOYSA-N 2,3-Dehydrosilybin Chemical compound C1=C(O)C(OC)=CC(C2C(OC3=CC=C(C=C3O2)C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 BVKQRAYKLBRNIK-UHFFFAOYSA-N 0.000 abstract 2
- SCPXVNQGJQJUJB-UHFFFAOYSA-N Dehydrosilybin Natural products COc1cc(ccc1O)C2Oc3ccc(cc3OC2CO)C4=C(O)C(=O)c5c(O)cc(O)cc5O4 SCPXVNQGJQJUJB-UHFFFAOYSA-N 0.000 abstract 2
- FDQAOULAVFHKBX-UHFFFAOYSA-N Isosilybin A Natural products C1=C(O)C(OC)=CC(C2C(OC3=CC(=CC=C3O2)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 FDQAOULAVFHKBX-UHFFFAOYSA-N 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- VLGROHBNWZUINI-UHFFFAOYSA-N Silybin Natural products COc1cc(ccc1O)C2OC3C=C(C=CC3OC2CO)C4Oc5cc(O)cc(O)c5C(=O)C4O VLGROHBNWZUINI-UHFFFAOYSA-N 0.000 abstract 2
- 230000000259 anti-tumor effect Effects 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 229940043175 silybin Drugs 0.000 abstract 2
- 235000014899 silybin Nutrition 0.000 abstract 2
- 229960004245 silymarin Drugs 0.000 abstract 2
- 235000017700 silymarin Nutrition 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI951047A IT1274549B (it) | 1995-05-23 | 1995-05-23 | Uso di flavanolignani per la preparazione di medicamenti ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno |
| PCT/EP1995/003993 WO1996037209A1 (en) | 1995-05-23 | 1995-10-10 | Use of flavanolignanes for the preparation of medicaments with antiproliferative activity in uterus, ovary and breast |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO975334D0 true NO975334D0 (no) | 1997-11-20 |
| NO975334L NO975334L (no) | 1997-11-20 |
| NO317153B1 NO317153B1 (no) | 2004-08-30 |
Family
ID=11371650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19975334A NO317153B1 (no) | 1995-05-23 | 1997-11-20 | Anvendelse av flavanolignaner for fremstilling av medikamenter med antiproliferativ aktivitet i uterus, ovarium og bryst |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US5912265A (no) |
| EP (1) | EP0828500B1 (no) |
| JP (1) | JP3178844B2 (no) |
| KR (1) | KR100290030B1 (no) |
| CN (1) | CN1148181C (no) |
| AT (1) | ATE268183T1 (no) |
| AU (1) | AU709802B2 (no) |
| CA (1) | CA2221753C (no) |
| DE (1) | DE69533112T2 (no) |
| DK (1) | DK0828500T3 (no) |
| ES (1) | ES2222466T3 (no) |
| FI (1) | FI119100B (no) |
| HU (1) | HU220627B1 (no) |
| IT (1) | IT1274549B (no) |
| NO (1) | NO317153B1 (no) |
| PL (1) | PL182064B1 (no) |
| PT (1) | PT828500E (no) |
| RU (1) | RU2161488C2 (no) |
| SI (1) | SI0828500T1 (no) |
| WO (1) | WO1996037209A1 (no) |
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| WO2000066232A2 (fr) | 1999-04-30 | 2000-11-09 | Salomon S.A. | Chassis articule |
| FR2792846B1 (fr) | 1999-04-30 | 2001-07-27 | Salomon Sa | Patin a roues en ligne du type a platine superieure articulee |
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| US9132117B2 (en) | 2013-06-17 | 2015-09-15 | Kgk Synergize, Inc | Compositions and methods for glycemic control of subjects with impaired fasting glucose |
| UA117141C2 (uk) | 2013-10-08 | 2018-06-25 | Селджин Корпорейшн | Склади (s)-3-(4-((4-(морфолінометил)бензил)оксі)-1-оксоізоіндолін-2-іл)піперидин-2,6-діону |
| CN104714708B (zh) * | 2013-12-11 | 2018-12-14 | 新益先创科技股份有限公司 | 控制点感测面板及其设计方法 |
| TW201540323A (zh) | 2014-01-15 | 2015-11-01 | Celgene Corp | 3-(5-胺基-2-甲基-4-側氧基-4h-喹唑啉-3-基)-哌啶-2,6-二酮之調配物 |
| US20170172921A1 (en) * | 2016-12-14 | 2017-06-22 | Mahmoud Reza Jaafari | Polyphenolic compounds encapsualated in long circulating liposomes and use thereof |
| WO2019233440A1 (zh) * | 2018-06-09 | 2019-12-12 | 江苏新元素医药科技有限公司 | 一类用于肝病治疗或预防的化合物 |
| CN109432084A (zh) * | 2018-12-26 | 2019-03-08 | 温州医科大学 | 一种抗癌组合物及其在药物制备中的应用 |
| KR102682905B1 (ko) * | 2020-10-22 | 2024-07-08 | 경희대학교 산학협력단 | 실리마린 매개된 셀레늄 나노입자 및 이의 용도 |
| CN112494479B (zh) * | 2020-12-28 | 2022-06-21 | 华中科技大学同济医学院附属同济医院 | 茶黄素在制备卵巢功能保护药物方面的应用 |
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|---|---|---|---|---|
| IT1215291B (it) * | 1985-07-17 | 1990-01-31 | Inverni Della Beffa Spa | Complessi di flavanolignani con fosfolipidi, loro preparazione e relative composizioni farmaceutiche. |
| GB2261434A (en) * | 1991-11-15 | 1993-05-19 | Inverni Della Beffa Spa | New radical scavenging and antipoperoxidant flavanolignans their preparation and formulations for therapeutic use |
| CN1047944C (zh) * | 1993-06-26 | 2000-01-05 | 曾庆通 | 一种治疗慢性肝炎的中药胶囊 |
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1995
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- 1995-10-10 PL PL95323450A patent/PL182064B1/pl not_active IP Right Cessation
- 1995-10-10 EP EP95935927A patent/EP0828500B1/en not_active Expired - Lifetime
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- 1995-10-10 CN CNB951978616A patent/CN1148181C/zh not_active Expired - Fee Related
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