NO980845L - Hvilende cellepopulasjoner for kjerneoverf÷ring - Google Patents

Hvilende cellepopulasjoner for kjerneoverf÷ring

Info

Publication number
NO980845L
NO980845L NO980845A NO980845A NO980845L NO 980845 L NO980845 L NO 980845L NO 980845 A NO980845 A NO 980845A NO 980845 A NO980845 A NO 980845A NO 980845 L NO980845 L NO 980845L
Authority
NO
Norway
Prior art keywords
cell populations
cell
resting cell
core transfer
transgenic animals
Prior art date
Application number
NO980845A
Other languages
English (en)
Norwegian (no)
Other versions
NO980845D0 (no
Inventor
Keith Henry Stockman Campbell
Ian Wilmut
Original Assignee
Roslin Inst Edinburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roslin Inst Edinburgh filed Critical Roslin Inst Edinburgh
Publication of NO980845D0 publication Critical patent/NO980845D0/no
Publication of NO980845L publication Critical patent/NO980845L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8773—Ovine embryos

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
NO980845A 1995-08-31 1998-02-27 Hvilende cellepopulasjoner for kjerneoverf÷ring NO980845L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9517780.4A GB9517780D0 (en) 1995-08-31 1995-08-31 Biological manipulation
PCT/GB1996/002099 WO1997007669A1 (fr) 1995-08-31 1996-08-30 Populations de cellules quiescentes pour transfert de noyau

Publications (2)

Publication Number Publication Date
NO980845D0 NO980845D0 (no) 1998-02-27
NO980845L true NO980845L (no) 1998-04-29

Family

ID=10779998

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980845A NO980845L (no) 1995-08-31 1998-02-27 Hvilende cellepopulasjoner for kjerneoverf÷ring

Country Status (23)

Country Link
US (5) US6147276A (fr)
EP (3) EP0849990B1 (fr)
JP (2) JP4081613B2 (fr)
KR (4) KR100533476B1 (fr)
CN (3) CN1769431A (fr)
AT (1) ATE199115T1 (fr)
AU (1) AU716956C (fr)
BR (1) BR9610034B1 (fr)
CA (1) CA2229568C (fr)
CZ (1) CZ60898A3 (fr)
DE (1) DE69611793T2 (fr)
DK (1) DK0849990T3 (fr)
ES (1) ES2155197T3 (fr)
GB (2) GB9517780D0 (fr)
HU (1) HUP9900234A3 (fr)
IL (1) IL123298A0 (fr)
NO (1) NO980845L (fr)
NZ (3) NZ316149A (fr)
PL (1) PL325331A1 (fr)
SG (1) SG75155A1 (fr)
SI (1) SI0849990T1 (fr)
WO (1) WO1997007669A1 (fr)
ZA (1) ZA967390B (fr)

Families Citing this family (228)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480772A (en) 1993-02-03 1996-01-02 Brandeis University In vitro activation of a nucleus
GB9517780D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517779D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
US7307198B2 (en) 1995-08-31 2007-12-11 Roslin Institute Ungulates produced by nuclear transfer of G1 cells
US6025155A (en) * 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6077697A (en) * 1996-04-10 2000-06-20 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US7696404B2 (en) 1996-08-19 2010-04-13 Advanced Cell Technology, Inc. Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions
CA2267220A1 (fr) 1996-10-11 1998-04-23 The Texas A & M University System Techniques permettant la production de cellules sexuelles primordiales et d'especes animales transgeniques
US6235969B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
US6215041B1 (en) * 1997-01-10 2001-04-10 University Of Mmassachusetts Cloning using donor nuclei from a non-quiesecent somatic cells
US20090092588A1 (en) * 1997-01-10 2009-04-09 University Of Massachusetts As Represented By Its Amherst Campus Cloned ungulate embryos and animals, use of cells, tissues and organs thereof for transplantation therapies including parkinson's disease
US5945577A (en) * 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
GB9703550D0 (en) * 1997-02-20 1997-04-09 Ppl Therapeutics Scotland Ltd Cell mediated transgenesis
US6011197A (en) 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells
JP2001522244A (ja) * 1997-04-24 2001-11-13 ユニバーシティ オブ ワシントン パルボウイルスベクターによる標的化した遺伝子改変
EP0989995A2 (fr) 1997-06-19 2000-04-05 The General Hospital Corporation Torsine, genes de torsine et leurs utilisations
US6921814B2 (en) 1997-06-19 2005-07-26 The General Hospital Corporation Torsin, torsin-related genes and methods of detecting neuronal disease
CN101003800A (zh) * 1997-07-03 2007-07-25 马萨诸塞大学 使用来自无血清饥饿的分化细胞的供体细胞核进行克隆
WO1999005266A2 (fr) * 1997-07-26 1999-02-04 Wisconsin Alumni Research Foundation Transfert de noyau entre des especes differentes
AU8817798A (en) * 1997-08-22 1999-03-16 Biotechnology And Biological Sciences Research Council, The Use of (mariner) transposan in the production of transgenic animals
EP1009818A1 (fr) * 1997-09-02 2000-06-21 Cancer Research Campaign Technology Limited Systeme de replication acellulaire et utilisations
AU1581899A (en) * 1997-10-28 1999-05-17 Biotransplant Incorporated Nuclear transfer for production of transgenic animal embryo
AU739902B2 (en) 1998-01-16 2001-10-25 Agrobiogen Gmbh Efficient nuclear transfer using fetal fibroblasts
US6331659B1 (en) * 1998-01-21 2001-12-18 University Of Hawaii Cumulus cells as nuclear donors
EP1067834A4 (fr) * 1998-03-16 2002-01-23 Garelag Pty Ltd Transfert de noyau de cellules porcines
AUPP294898A0 (en) * 1998-04-15 1998-05-07 Monash University Method of nuclear transfer
GB9808325D0 (en) * 1998-04-20 1998-06-17 Ltr Ciz Di Associazione Italia Source of nuclei for nuclear transfer
GB9809178D0 (en) * 1998-04-29 1998-07-01 Univ Edinburgh Nuclear reprogramming of somatic cells
WO2000022098A1 (fr) * 1998-10-12 2000-04-20 Geron Bio-Med Limited Ovocytes porcins presentant des capacites de developpement ameliorees
US6580017B1 (en) 1998-11-02 2003-06-17 Genzyme Transgenics Corporation Methods of reconstructed goat embryo transfer
AU2003204830B2 (en) * 1998-11-02 2007-08-30 Gtc Biotherapeutics, Inc. Transgenic and cloned mammals
CA2350233A1 (fr) * 1998-11-02 2000-05-11 Trustee Of Tufts College Mammiferes transgeniques et clones
US6781030B1 (en) 1998-11-02 2004-08-24 Trustee Of Tufts College, Ballou Hall Methods for cloning mammals using telophase oocytes
EP1375654A3 (fr) * 1998-11-02 2008-01-16 GTC Biotherapeutics, Inc. Mammifères trangéniques et clonés
EP1130961B1 (fr) 1998-11-19 2009-04-08 Pharming Intellectual Property BV Stabilisation du lait provenant d'animaux transgeniques
US6700037B2 (en) 1998-11-24 2004-03-02 Infigen, Inc. Method of cloning porcine animals
US6258998B1 (en) 1998-11-24 2001-07-10 Infigen, Inc. Method of cloning porcine animals
AU780809B2 (en) * 1999-01-13 2005-04-21 Revivicor Inc Double nuclear transfer method and results thereof
GB9903805D0 (en) * 1999-02-20 1999-04-14 Univ Sheffield Pluripotential cells-1
GB9903804D0 (en) * 1999-02-20 1999-04-14 Univ Sheffield Pluripotential cells-2
EP1179000A4 (fr) 1999-02-26 2005-10-12 Millennium Pharm Inc Proteines secretees et leurs utilisations
DK1159415T3 (da) 1999-03-04 2010-05-03 Revivicor Inc Genetisk modifikation af somatiske celler og anvendelse deraf
US20020012660A1 (en) * 1999-03-04 2002-01-31 Alan Colman Method of preparing a somatic cells for nuclear transfer
BR0010588A (pt) * 1999-04-28 2003-07-22 Univ Montreal Oócitos enucleados de telofase para transferência nuclear
AU4389699A (en) * 1999-06-04 2000-12-28 Istituto Zootecnico E Caseario Per La Sardegna Process for reconstructing a non-human animal embryo by nuclear transfer and preparing the animal therefrom, and embryos and animals obtained thereby
AU5553600A (en) 1999-06-23 2001-01-31 Ppl Therapeutics (Scotland) Ltd Fusion proteins incorporating lysozyme
WO2001000793A1 (fr) * 1999-06-30 2001-01-04 Hwang, Woo-Suk Procede d'obtention d'embryons humains clones au moyen de techniques de transplantation inter-especes de noyaux
JP3652308B2 (ja) * 1999-06-30 2005-05-25 ソウル ナショナル ユニバーシティー インダストリー ファウンデーション クローンウシの生産方法
CA2334954A1 (fr) * 1999-06-30 2001-01-04 Woo-Suk Hwang Procede de production de tigres clones utilisant une technique de transplantation de noyau inter-especes
AU782286B2 (en) * 1999-06-30 2005-07-14 Advanced Cell Technology, Inc. Cytoplasmic transfer to de-differentiate recipient cells
US7291714B1 (en) 1999-06-30 2007-11-06 Millennium Pharmaceuticals, Inc. Glycoprotein VI and uses thereof
IL147972A0 (en) 1999-08-23 2002-09-12 Dana Farber Cancer Inst Inc Ge Pd-1, a receptor for b7-4 and uses therefor
WO2002064799A2 (fr) 1999-09-28 2002-08-22 Transkaryotic Therapies, Inc. Arn messager optimise
EP2275559A3 (fr) 1999-09-28 2011-03-23 Shire Human Genetic Therapies, Inc. ARN messager (ARN-m) optimisé
BR0014448A (pt) * 1999-09-30 2002-09-17 Genzyme Transgenics Corp Métodos de produção de mamìferos clonados e trangênicos
US7074983B2 (en) 1999-11-19 2006-07-11 Kirin Beer Kabushiki Kaisha Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin
US7820878B2 (en) * 1999-11-19 2010-10-26 Kyowa Hakko Kirin Co., Ltd. Production of ungulates, preferably bovines that produce human immunoglobulins
KR100417566B1 (ko) * 1999-11-19 2004-02-05 한국생명공학연구원 체세포 핵치환 복제수정란의 대량생산방법
US7414170B2 (en) 1999-11-19 2008-08-19 Kirin Beer Kabushiki Kaisha Transgenic bovines capable of human antibody production
AU1777301A (en) * 1999-11-19 2001-05-30 Hematech, Llc Production of ungulates, preferably bovines that produce human immunoglobulins
US6635802B1 (en) * 2000-01-10 2003-10-21 The Texas A&M University System Nuclear transfer using cells cultured in serum starvation media containing apoptosis inhibitors
GB0001401D0 (en) * 2000-01-22 2000-03-08 Univ Edinburgh Methods for amplifying genetic material and use thereof
WO2001068831A2 (fr) 2000-03-15 2001-09-20 The University Of Georgia Research Foundation, Inc. Reprogrammation effective de materiel nucleaire chez des mammiferes
US20040033600A1 (en) 2001-03-21 2004-02-19 Palli Subba Reddy Ecdysone receptor-based inducible gene expression system
GB2360522A (en) 2000-03-24 2001-09-26 Geron Corp A strategy for maintaining pregnancy
AU2001261650A1 (en) * 2000-05-15 2001-11-26 Geron Corporation Ovine tissue for xenotransplantation
ES2331407T3 (es) 2000-06-05 2010-01-04 Genetics Institute, Llc Composiciones, kits y procedimientos de identificacion y modulacion de diabetes tipo i.
US7432059B2 (en) 2000-06-28 2008-10-07 Dana-Farber Cancer Institute, Inc. Methods of identifying compounds that upmodulate T cell activation in the presence of a PD-1 mediated signal
AU2001278204A1 (en) * 2000-08-01 2002-02-13 Xy Genetics, Llc Methods of selecting and cloning animals
CN1468250A (zh) 2000-08-03 2004-01-14 ��ķһ����˹��̹ 在转基因动物中产生人源化抗体
US6677500B2 (en) 2000-08-15 2004-01-13 Board Of Trustees Of The University Of Illinois Ungulates expressing exogenous IGF-I in their milk
AU2001291558A1 (en) * 2000-09-06 2002-03-22 Nexia Biotechnologies, Inc. Generation of transgenic animals using nuclear transfer and oocytes at the germinal vesicle stage
FR2814642B1 (fr) 2000-10-03 2005-07-01 Ass Pour Le Dev De La Rech En Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee
US8105825B2 (en) * 2000-10-03 2012-01-31 Intrexon Corporation Multiple inducible gene regulation system
US20040029825A1 (en) * 2001-10-03 2004-02-12 Davies Christopher J Methods of minimizing immunological rejection of a nuclear transfer fetus
BR0115728A (pt) 2000-11-28 2003-09-23 Wyeth Corp Análise da expressão de ácidos nucléicos kiaa e polipeptìdeos úteis no diagnóstico e tratamento de cáncer de próstata
WO2002044418A2 (fr) 2000-11-28 2002-06-06 Wyeth Analyse de l'expression des acides nucleiques fkbp et polypeptides utiles dans le diagnostic et le traitement du cancer de la prostate
MXPA03005624A (es) 2000-12-22 2004-12-03 Vaurox Llc Metodos para clonar mamiferos usando cromatina reprogramada del donador o celulas donadoras.
EP2138583A1 (fr) 2000-12-22 2009-12-30 Institut National De La Recherche Agronomique Expression position-indépendante et tissus-spécifique d' un transgène dans le lait d'animaux transgéniques
US7491534B2 (en) 2000-12-22 2009-02-17 Kirin Holdings Kabushiki Kaisha Methods for altering cell fate to generate T-cells specific for an antigen of interest
US20020142397A1 (en) 2000-12-22 2002-10-03 Philippe Collas Methods for altering cell fate
EP1860199B1 (fr) 2001-01-12 2014-03-05 Exelixis, Inc. Modulation de signal de récépteur d'insuline
MXPA03006751A (es) 2001-01-30 2005-04-08 Amy K Rebholtz Metodos para el manejo de recipientes para embriones.
AU2002250020A1 (en) * 2001-02-02 2002-08-19 Erik Forsberg Method of cloning transgenic mammalian animals using pseudonuclei
ES2392508T3 (es) * 2001-02-20 2012-12-11 Intrexon Corporation Receptores X retinoides quiméricos y su uso en un sistema inducible de expresión génica basado en receptores de ecdisona novedoso
JP2004524843A (ja) 2001-02-23 2004-08-19 イーラン ファーマスーティカルズ、インコーポレイテッド Ｂａｃｅ−１のトランスジェニックノックアウト
JP2002262716A (ja) * 2001-03-07 2002-09-17 National Agricultural Research Organization 株化細胞を用いて家畜個体を作出する方法
US20020132346A1 (en) * 2001-03-08 2002-09-19 Jose Cibelli Use of RNA interference for the creation of lineage specific ES and other undifferentiated cells and production of differentiated cells in vitro by co-culture
AUPR363701A0 (en) 2001-03-09 2001-04-05 Garelag Pty Ltd Method for the production of nuclear transfer embryos
US8981061B2 (en) 2001-03-20 2015-03-17 Novo Nordisk A/S Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
US7126039B2 (en) * 2001-03-21 2006-10-24 Geron Corporation Animal tissue with carbohydrate antigens compatible for human transplantation
EP1370132A2 (fr) * 2001-03-21 2003-12-17 Geron Corporation Utilisation de la transcriptase inverse de la telomerase dans la creation d'animaux knockout homozygotes
EP2388590A1 (fr) 2001-04-02 2011-11-23 Dana Farber Cancer Institute PD-1, récepteur pour B7-4 et utilisations associées
US20030027330A1 (en) * 2001-04-02 2003-02-06 Robert Lanza Method for facilitating the production of differentiated cell types and tissues from embryonic and adult pluripotent and multipotent cells
WO2002083855A2 (fr) 2001-04-16 2002-10-24 Wyeth Holdings Corporation Nouveaux cadres de lecture ouverts de streptococcus pneumoniae codant pour des antigenes polypeptidiques, et leurs utilisations
WO2002092791A1 (fr) * 2001-05-14 2002-11-21 Stell Tissus ou organes utilises dans la xenotransplantation
US20030153044A1 (en) * 2001-05-14 2003-08-14 Monika Liljedahl Tissues or organs for use in xenotransplantation
AU2002326353A1 (en) * 2001-07-09 2003-01-29 Alexion Pharmaceuticals Inc. Cloned non-human mammals from contact inhibited donor cells
EP1900815B1 (fr) 2001-07-12 2016-09-07 University of Massachusetts Production in vivo de petits ARN interférents qui modèrent le silençage génique
EP1412371B1 (fr) 2001-07-12 2016-02-24 University of Massachusetts Production in vivo of small interfering rnas that mediate gene silencing
AU2002326483A1 (en) * 2001-07-31 2003-02-17 Simon Eric Aspland Genetically modified cows having reduced susceptibility to mad cow disease
US20030211603A1 (en) * 2001-08-14 2003-11-13 Earp David J. Reprogramming cells for enhanced differentiation capacity using pluripotent stem cells
US7091006B2 (en) 2001-11-09 2006-08-15 Dana-Farber Cancer Institute, Inc. PGC-1β, a novel PGC-1 homologue and uses therefor
US20030134422A1 (en) * 2002-01-16 2003-07-17 Sayre Chauncey Bigelow Stem cell maturation for all tissue lines
US20050170506A1 (en) * 2002-01-16 2005-08-04 Primegen Biotech Llc Therapeutic reprogramming, hybrid stem cells and maturation
US20050090004A1 (en) * 2003-01-16 2005-04-28 Sayre Chauncey B. Stem cell maturation for all tissue lines
CA2474486C (fr) * 2002-01-23 2013-05-14 The University Of Utah Research Foundation Mutagenese chromosomique ciblee au moyen de nucleases en doigt a zinc
KR100502695B1 (ko) * 2002-02-28 2005-07-25 한국생명공학연구원 형질전환 효율이 향상된 복제수정란의 대량 생산 방법
US20030232410A1 (en) * 2002-03-21 2003-12-18 Monika Liljedahl Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
GB0207299D0 (en) * 2002-03-28 2002-05-08 Franks Christopher R Stem cell therapy
CN1650003A (zh) * 2002-04-01 2005-08-03 Gtc生物治疗学公司 选择用于哺乳动物种中核转移的细胞系的方法
US20030207448A1 (en) * 2002-05-06 2003-11-06 Revera Gregory Henry Methodologies for the creation of pluripotent or multipotent human stem cells without creating or destroying a human embryo
GB0211904D0 (en) * 2002-05-23 2002-07-03 Medical Res Council Nuclear transfer
WO2003104423A2 (fr) * 2002-06-11 2003-12-18 Roy Ogle Cellules souches d'origine meningee
US7612250B2 (en) * 2002-07-29 2009-11-03 Trustees Of Tufts College Nuclear transfer embryo formation method
EP2311978A1 (fr) 2002-08-20 2011-04-20 Millennium Pharmaceuticals, Inc. Compositions, kits et procédés d'identification, évaluation, prévention et thérapie du cancer du col de lutérus
WO2004037977A2 (fr) 2002-09-05 2004-05-06 California Institute Of Thechnology Utilisation de nucleases chimeres pour stimuler le ciblage de genes
AU2003300027A1 (en) 2002-10-10 2004-05-04 Wyeth Compositions, organisms and methodologies employing a novel human kinase
US20040077077A1 (en) * 2002-10-18 2004-04-22 Xiangzhong Yang Novel methods for the production of cloned mammals, mammals cloned according to the methods, and methods of use of same
CA2503491A1 (fr) 2002-10-24 2004-05-06 Wyeth Compositions, organismes et procedes faisant appel a une nouvelle proteine phosphatase humaine
NZ539459A (en) 2002-11-08 2009-02-28 Kirin Pharma Kk Transgenic ungulates having reduced prion protein activity and uses thereof
US7611839B2 (en) 2002-11-21 2009-11-03 Wyeth Methods for diagnosing RCC and other solid tumors
US7297525B2 (en) 2002-11-27 2007-11-20 Wyeth Composition employing a novel human kinase
JP2006508676A (ja) * 2002-12-10 2006-03-16 ジーティーシー バイオセラピューティックス インコーポレイテッド 追加の核移植のための細胞ドナーとして体細胞核移植胚を利用する方法および系
CA2936612C (fr) 2002-12-20 2017-11-21 Celera Corporation Polymorphismes atf6 associes a une infarctus du myocarde, methode de detection et utilisations associees
EP1581812B1 (fr) 2003-01-06 2008-07-16 Wyeth Compositions et procede permettant de diagnostiquer et de traiter les cancers du colon
FR2855183B1 (fr) 2003-05-23 2005-08-12 Agronomique Inst Nat Rech Procede de clonage du rat par transfert nucleaire
DK1633767T3 (en) 2003-06-02 2019-03-25 Univ Massachusetts METHODS AND COMPOSITIONS FOR MANAGING THE EFFECT OF RNA SILENCING
ES2357116T5 (es) 2003-06-02 2021-09-03 Univ Massachusetts Métodos y composiciones para mejorar la eficacia y especificad de FNAi
US8409861B2 (en) * 2003-08-08 2013-04-02 Sangamo Biosciences, Inc. Targeted deletion of cellular DNA sequences
US20120196370A1 (en) 2010-12-03 2012-08-02 Fyodor Urnov Methods and compositions for targeted genomic deletion
US7888121B2 (en) * 2003-08-08 2011-02-15 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
US11311574B2 (en) 2003-08-08 2022-04-26 Sangamo Therapeutics, Inc. Methods and compositions for targeted cleavage and recombination
ATE482979T1 (de) 2003-08-14 2010-10-15 Exelixis Inc Ups als den beta-catenin-pfad modifizierende substanzen und anwendungsverfahren
CN102517381A (zh) 2003-10-07 2012-06-27 千年药品公司 用于鉴定、评价、预防和治疗卵巢癌的核酸分子和蛋白质
US7951532B2 (en) 2003-11-12 2011-05-31 Children's Hospital Medical Center Method of screening a midkine modulating agent
WO2005056837A2 (fr) 2003-11-26 2005-06-23 Applera Corporation Polymorphismes genetiques associes a des troubles cardiovasculaires et a une reponse au medicament, leurs procedes de detection et d'utilisation
US7972854B2 (en) 2004-02-05 2011-07-05 Sangamo Biosciences, Inc. Methods and compositions for targeted cleavage and recombination
EP1749102A4 (fr) 2004-04-22 2009-02-25 Kirin Pharma Kk Animaux transgeniques et leurs utilisations
EP2423326B1 (fr) 2004-05-07 2014-01-08 Celera Corporation Polymorphism génétique associée à des techniques de detection de cirrhose du foie et utilisation de cette polymorphism
JP2006081542A (ja) * 2004-08-18 2006-03-30 Institute Of Physical & Chemical Research クローン哺乳動物の作成方法
JP2008517931A (ja) 2004-10-22 2008-05-29 ダナ−ファーバー キャンサー インスティチュート，インコーポレイテッド 脂質関連疾患および障害を処置するための、ＰＧＣ−１βを調節するための方法および組成物
GB0426146D0 (en) 2004-11-29 2004-12-29 Bioxell Spa Therapeutic peptides and method
CN1274829C (zh) 2004-12-10 2006-09-13 四川大学华西医院 抗eb病毒所致肿瘤多肽及其应用与制备方法
EP1856296A2 (fr) 2005-03-11 2007-11-21 Applera Corporation Polymorphismes genetiques associes a des maladies cardiaques coronariennes, methodes de detection et d'utilisation desdits polymorphismes
US20060286666A1 (en) * 2005-06-17 2006-12-21 Kang Ji Y Methods and apparatuses for culturing stem cell using biomaterial shell
EP1924697A2 (fr) * 2005-06-29 2008-05-28 Cameron Clokie Production de protéines morphogéniques osseuses dans des mammiféres transgéniques
KR100733012B1 (ko) 2005-07-26 2007-06-28 재단법인서울대학교산학협력재단 복제된 개과 동물 및 이의 생산 방법
EP3138403A1 (fr) 2005-08-09 2017-03-08 Revivicor, Inc. Ongulés transgéniques exprimant la ctla4-ig et leurs utilisations
AU2006287315B2 (en) 2005-09-09 2013-02-21 The Johns Hopkins University Manipulation of regulatory T cell and DC function by targeting neuritin gene using antibodies, agonists and antagonists
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
US7799530B2 (en) 2005-09-23 2010-09-21 Celera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
US7695911B2 (en) 2005-10-26 2010-04-13 Celera Corporation Genetic polymorphisms associated with Alzheimer's Disease, methods of detection and uses thereof
US8173860B2 (en) 2006-04-21 2012-05-08 Gtc Biotherapeutics, Inc. Non-human transgenic mammal expressing a human FcRn on its mammary gland cells and expressing a transgenic protein-human Fc-domain fusion
ATE536374T1 (de) 2006-09-01 2011-12-15 Therapeutic Human Polyclonals Inc Erhöhte expression von humanem oder humanisiertem immunglobulin bei nicht-humanen transgenen tieren
WO2008033239A2 (fr) 2006-09-11 2008-03-20 Applera Polymorphismes genetiques lies au psoriasis, methodes de detection et utilisations associees
CA2915679C (fr) 2006-10-20 2017-12-12 Celera Corporation Polymorphismes genetiques associes a la thrombose veineuse, procedes pour les detecter et utilisations
KR101398220B1 (ko) * 2006-10-30 2014-05-22 건국대학교 산학협력단 형질전환 배아 생성방법
US20100205678A1 (en) * 2007-01-05 2010-08-12 Overstrom Eric W Oocyte spindle-associated factors improve somatic cell cloning
KR100829426B1 (ko) 2007-01-17 2008-05-15 재단법인서울대학교산학협력재단 복제개의 생산 방법
US20080222745A1 (en) * 2007-03-07 2008-09-11 Utah State University Colcemid-Treatment of Oocytes to enhance Nuclear Transfer Cloning
KR100868245B1 (ko) 2007-05-29 2008-11-11 강원대학교산학협력단 데메콜친 처리에 의한 효율적인 복제 동물의 생산방법
US8663980B2 (en) 2007-10-26 2014-03-04 Janssen Biotech, Inc. Vectors, host cells, and methods of production and uses
US8039212B2 (en) 2007-11-05 2011-10-18 Celera Corporation Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
EP2232985A4 (fr) 2008-01-04 2011-02-16 Seoul Nat Univ Ind Foundation Procédé de production de canidés transgéniques clonés
US20090221620A1 (en) 2008-02-20 2009-09-03 Celera Corporation Gentic polymorphisms associated with stroke, methods of detection and uses thereof
JP5670755B2 (ja) 2008-03-12 2015-02-18 ザ ロックフェラー ユニバーシティ 翻訳プロファイリング及び分子表現型解析のための方法及び組成物
US8288094B2 (en) 2008-04-09 2012-10-16 Institut Pasteur APOBEC3 mediated DNA editing
WO2009134130A2 (fr) 2008-05-02 2009-11-05 Pharming Intellectual Property Bv Traitement de saignement par un fibrinogène de faible demi-vie
DK2295538T3 (en) * 2008-07-07 2015-12-21 Takara Bio Inc Process for producing a pluripotent stem cell
EP2310525B1 (fr) 2008-07-09 2014-02-26 Celera Corporation Polymorphismes génétiques associés à des maladies cardiovasculaires et procédés de détection et d'utilisation de ceux-ci
US9181315B2 (en) 2009-01-08 2015-11-10 Dana-Farber Cancer Institute, Inc. Compositions and methods for induced brown fat differentiation
EP2421980A2 (fr) 2009-04-23 2012-02-29 Transposagen Biopharmaceuticals, Inc. Rats génétiquement modifiés comme modèles de cancer
EP2267153A1 (fr) 2009-05-26 2010-12-29 Université Claude Bernard Lyon 1 Identification de la mutation du gène unc5c du récepteur de la nétrine-1 dans des cancers solides
US9314005B2 (en) 2009-07-01 2016-04-19 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for severe combined immunodeficiency (SCID)
EP2456876A2 (fr) 2009-07-24 2012-05-30 Transposagen Biopharmaceuticals, Inc. Modèles rats génétiquement modifiös pour les voies de signalisation cytokine-cytokine
EP2460016A2 (fr) 2009-07-30 2012-06-06 Transposagen Biopharmaceuticals, Inc. Modèles de rat génétiquement modifiés pour pharmacocinétique
EP2461672A2 (fr) 2009-08-05 2012-06-13 Transposagen Biopharmaceuticals, Inc. Modèles de rats génétiquement modifiés pour le métabolisme de médicaments
EP2467013A2 (fr) 2009-08-20 2012-06-27 Transposagen Biopharmaceuticals, Inc. Modèles de rat génétiquement modifié pour l'analyse de la douleur
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
EP2526424A2 (fr) 2010-01-22 2012-11-28 Dana-Farber Cancer Institute, Inc. Compositions, kits, et procédés d'identification, d'évaluation, de prévention, et de thérapie de troubles métaboliques
TWI518325B (zh) 2010-02-04 2016-01-21 自治醫科大學 對ａｌｋ抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
CA2794483C (fr) 2010-03-26 2020-07-07 Trustees Of Dartmouth College Vista, une proteine mediatrice regulatrice des lymphocytes t, agents de liaison a vista et utilisation associee
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
US8383793B2 (en) 2010-04-15 2013-02-26 St. Jude Children's Research Hospital Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
US20110269735A1 (en) 2010-04-19 2011-11-03 Celera Corporation Genetic polymorphisms associated with statin response and cardiovascular diseases, methods of detection and uses thereof
WO2012020077A1 (fr) 2010-08-11 2012-02-16 Inserm (Institut Mational De La Santé Et De La Recherche Médicale) Procédés de culture d'un embryon jusqu'au stade de développement blastocyste
US20120108651A1 (en) 2010-11-02 2012-05-03 Leiden University Medical Center (LUMC) Acting on Behalf of Academic Hospital Leiden (AZL) Genetic polymorphisms associated with venous thrombosis and statin response, methods of detection and uses thereof
US8748178B2 (en) 2010-11-23 2014-06-10 The New York Stem Cell Foundation Method for producing pluripotent stem cells
NZ759163A (en) 2011-02-14 2023-03-31 Revivicor Inc Genetically modified pigs for xenotransplantation of vascularized xenografts and derivatives thereof
WO2012129198A1 (fr) 2011-03-23 2012-09-27 Transposagen Biopharmaceuticals, Inc. Modèles de rat génétiquement modifiés pour l'étude de l'obésité et du diabète
CN105112450A (zh) 2011-05-16 2015-12-02 密苏里大学管理者 抗猪生殖与呼吸综合征病毒的动物
US10093705B2 (en) 2011-09-13 2018-10-09 Dana-Farber Cancer Institute, Inc. Compositions and methods for brown fat induction and activity using FNDC5
CN102391989A (zh) * 2011-10-12 2012-03-28 扬州大学 转基因动物重组产物精确分析检验方法
PL2814842T3 (pl) 2012-02-15 2018-12-31 Novo Nordisk A/S Przeciwciała wiążące białko 1 rozpoznające peptydoglikan
US9550830B2 (en) 2012-02-15 2017-01-24 Novo Nordisk A/S Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
CN108103069B (zh) 2012-02-15 2021-08-10 诺和诺德股份有限公司 结合并阻断髓样细胞表达的触发受体-1 (trem-1)的抗体
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
FI3421486T3 (fi) 2012-06-22 2023-12-15 Dartmouth College Uusia vista-ig-rakenteita ja vista-ig:n käyttö autoimmuuni-, allergia- ja tulehdushäiriöiden hoitamiseksi
EP2892558B1 (fr) 2012-09-07 2019-04-10 The Trustees Of Dartmouth College Modulateurs vista de diagnostic et de traitement de cancer
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
KR20160002713A (ko) 2013-02-13 2016-01-08 라보라토이레 프란카이즈 듀 프락티온네먼트 에트 데스 바이오테크놀로지스 고도로 갈락토실화된 항-tnf-알파 항체 및 이의 용도
BR112015019348A2 (pt) 2013-02-13 2017-08-22 Lab Francais Du Fractionnement Métodos para produção de proteína com glicosilação modificada e com sialilação aumentada, para aumentar a atividade de sialil transferase na glândula mamária e para produzir sialil transferase, proteína com glicosilação modificada ou proteína com sialilação aumentada, composição, sialil transferase, mamífero transgênico, e, célula epitelial mamária
EP2993234B1 (fr) 2013-04-30 2018-10-10 Konkuk University Industrial Cooperation Corp. Vecteur ciblant l'acide cmp-acétylneuraminique hydroxylase, animal transgénique transduit par le vecteur pour une xénogreffe, et son procédé de production
CN114163529B (zh) 2013-12-24 2024-12-13 杨森制药公司 抗vista抗体及片段
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
EP3094736A4 (fr) 2014-01-14 2017-10-25 Dana-Farber Cancer Institute, Inc. Compositions et méthodes pour l'identification, l'évaluation, la prévention, et le traitement d'un mélanome à l'aide d'isoformes de pd-l1
JP6997619B2 (ja) 2014-06-11 2022-01-17 キャシー・エイ・グリーン 液性免疫の抑制または増進のための、ｖｉｓｔａアゴニスト及びｖｉｓｔａアンタゴニストの使用
SI3172232T1 (sl) 2014-07-17 2024-05-31 Novo Nordisk A/S Na mesto usmerjena mutageneza protiteles TREM-1 za zmanjšanje viskoznosti
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
JP2018505911A (ja) 2014-12-05 2018-03-01 イミュネクスト，インコーポレーテッド 推定上のｖｉｓｔａ受容体としてのｖｓｉｇ８の同定と、ｖｉｓｔａ／ｖｓｉｇ８調節剤を産生するためのその使用
CN107257624B (zh) 2014-12-09 2021-07-13 瑞泽恩制药公司 具有人源化分化簇274基因的非人动物
CN104823921A (zh) * 2015-05-21 2015-08-12 蒙汉勤 一种用于人体烧伤皮肤移植及医学实验的小型香猪的饲养技术
CN107922497B (zh) 2015-06-24 2022-04-12 詹森药业有限公司 抗vista抗体和片段
FR3038517B1 (fr) 2015-07-06 2020-02-28 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Utilisation de fragments fc modifies en immunotherapie
BR112018002417A2 (pt) 2015-08-06 2018-09-18 Univ Missouri animal não humano ou descendente do mesmo ou uma célula de animal, animal suíno, descendente ou célula, célula, descendente, método de reprodução, população de animais, método para aumentar uma resistência de animal, molécula de ácido nucleico, ácido nucleico e ácido nucleico isolado
CA3002676A1 (fr) 2015-10-29 2017-05-04 Dana-Farber Cancer Institute, Inc. Procedes pour identifier, evaluer, prevenir et traiter des troubles metaboliques au moyen de pm20d1 et d'acides amines n-lipides
WO2017137830A1 (fr) 2016-02-12 2017-08-17 Janssen Pharmaceutica Nv Anticorps anti-vista (b7h5)
AU2017250294B2 (en) 2016-04-15 2022-07-21 Immunext Inc. Anti-human VISTA antibodies and use thereof
MA49651A (fr) 2017-07-19 2021-04-28 Childrens Medical Center Compositions et procédés pour traiter des maladies associées à un défaut d'empreinte
EA202092302A1 (ru) 2018-04-02 2021-02-02 Бристол-Майерс Сквибб Компани Антитела к trem-1 и их применения
WO2019195738A1 (fr) 2018-04-06 2019-10-10 Children's Medical Center Corporation Compositions et procédés de reprogrammation de cellules somatiques et de modulation d'impression
US11160260B2 (en) 2018-04-17 2021-11-02 The Curators Of The University Of Missouri Methods for protecting porcine fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)
WO2020041360A1 (fr) 2018-08-21 2020-02-27 Quidel Corporation Anticorps dbpa et leurs utilisations
WO2021127547A2 (fr) 2019-12-19 2021-06-24 Quidel Corporation Fusion d'anticorps monoclonaux
IL302983A (en) 2020-11-20 2023-07-01 Revivicor Inc Multitransgenic pigs with growth hormone receptor silencing for xenotransplantation
KR20240099180A (ko) 2021-09-20 2024-06-28 레비비코르 인코포레이션 이종이식을 위한 10개의 유전자 변형을 포함하는 다중전이유전자 돼지

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890003947B1 (ko) * 1985-12-11 1989-10-13 가부시기가이샤 시마즈세이사구쇼 세포융합장치
US5057420A (en) * 1987-06-05 1991-10-15 Granada Biosciences, Inc. Bovine nuclear transplantation
GB8714426D0 (en) * 1987-06-19 1987-07-22 Agricultural & Food Res Culture technique
CA2059199A1 (fr) * 1992-01-10 1993-07-11 Steen Willadsen Methode d'obtention d'oeufs de mammiferes, reconstitues et a maturite, par transplantation du noyau
GB2265909B (en) * 1992-04-01 1996-03-20 Inst Of Animal Physiology And Fusion of donor nucleus with recipient cytoplast in the absence of calcium ion
DE69332758D1 (de) * 1992-09-22 2003-04-17 Us Gov Health & Human Serv Taxol zur behandlung von lymphomen und brustkrebs und zur verminderung der multi-drug resistenz gegen taxol
CA2092258A1 (fr) * 1992-12-30 1994-07-01 Steven L. Stice Cellules de donneur synchronisees pour le transfert de noyaux chez les bovins
US5496720A (en) * 1993-02-10 1996-03-05 Susko-Parrish; Joan L. Parthenogenic oocyte activation
US5523226A (en) 1993-05-14 1996-06-04 Biotechnology Research And Development Corp. Transgenic swine compositions and methods
DK0711158T4 (da) * 1993-07-29 2008-11-03 Us Gov Health & Human Serv Metode til behandling af atherosclerose eller restenose ved anvendelse af mikrotubulus-stabiliserende middel
WO1995016770A1 (fr) * 1993-12-17 1995-06-22 Abs Global, Inc. Cellules souches embryonnaires derivees de cellules du stade preblastocyste d'ongule et leur utilisation pour produire des ongules chimeres et transgeniques clones
DE69430014D1 (de) * 1993-12-23 2002-04-04 Infigen Inc EMBRYONALE STAMMZELLEN von Huftieren ALS KERNDONATOREN UND KERNTRANSFERTECHNIKEN ZUR HERSTELLUNG CHIMÄRER UND TRANSGENER TIERE
GB9417831D0 (en) * 1994-09-05 1994-10-26 Biotech & Biolog Scien Res Biological manipulation
GB9517779D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517780D0 (en) * 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
US7307198B2 (en) * 1995-08-31 2007-12-11 Roslin Institute Ungulates produced by nuclear transfer of G1 cells
US6235969B1 (en) 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
US6215041B1 (en) 1997-01-10 2001-04-10 University Of Mmassachusetts Cloning using donor nuclei from a non-quiesecent somatic cells
US5945577A (en) 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
US6011197A (en) 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells
WO1999005266A2 (fr) * 1997-07-26 1999-02-04 Wisconsin Alumni Research Foundation Transfert de noyau entre des especes differentes
US6225243B1 (en) * 1998-08-03 2001-05-01 Bba Nonwovens Simpsonville, Inc. Elastic nonwoven fabric prepared from bi-component filaments
WO2000022098A1 (fr) * 1998-10-12 2000-04-20 Geron Bio-Med Limited Ovocytes porcins presentant des capacites de developpement ameliorees
US20050156424A1 (en) * 2000-02-29 2005-07-21 Thyssenkrupp Presta Ag Steering column and manufacturing method thereof

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