NO983529L - Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler - Google Patents
Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midlerInfo
- Publication number
- NO983529L NO983529L NO983529A NO983529A NO983529L NO 983529 L NO983529 L NO 983529L NO 983529 A NO983529 A NO 983529A NO 983529 A NO983529 A NO 983529A NO 983529 L NO983529 L NO 983529L
- Authority
- NO
- Norway
- Prior art keywords
- hydrogen
- approx
- dihydrobenzofuran
- inflammatory agents
- compounds useful
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- HBEDSQVIWPRPAY-UHFFFAOYSA-N 2,3-dihydrobenzofuran Chemical compound C1=CC=C2OCCC2=C1 HBEDSQVIWPRPAY-UHFFFAOYSA-N 0.000 title 2
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004429 atom Chemical group 0.000 abstract 3
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/595,087 US5821250A (en) | 1996-02-01 | 1996-02-01 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| PCT/US1997/001313 WO1997028146A1 (en) | 1996-02-01 | 1997-01-30 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO983529D0 NO983529D0 (no) | 1998-07-31 |
| NO983529L true NO983529L (no) | 1998-09-28 |
Family
ID=24381679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO983529A NO983529L (no) | 1996-02-01 | 1998-07-31 | Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US5821250A (de) |
| EP (1) | EP0883616B1 (de) |
| JP (1) | JP3202245B2 (de) |
| KR (1) | KR100322401B1 (de) |
| CN (1) | CN1109679C (de) |
| AT (1) | ATE274506T1 (de) |
| AU (1) | AU730264B2 (de) |
| BR (1) | BR9707333A (de) |
| CA (1) | CA2244411A1 (de) |
| DE (1) | DE69730415T2 (de) |
| DK (1) | DK0883616T3 (de) |
| ES (1) | ES2229332T3 (de) |
| MX (1) | MX9806248A (de) |
| NO (1) | NO983529L (de) |
| WO (1) | WO1997028146A1 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7048906B2 (en) * | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| DE19548708A1 (de) * | 1995-12-23 | 1997-06-26 | Merck Patent Gmbh | Cyclische Sulfone |
| WO1999031090A1 (en) * | 1997-12-15 | 1999-06-24 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Dihydrobenzofurans |
| US6667299B1 (en) * | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
| AU2002322720B2 (en) | 2001-07-25 | 2008-11-13 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| US7235249B2 (en) | 2002-03-28 | 2007-06-26 | The Procter & Gamble Company | Methods for regulating the condition of mammalian keratinous tissue via topical application of vitamin B6 compositions |
| US7098189B2 (en) * | 2002-12-16 | 2006-08-29 | Kimberly-Clark Worldwide, Inc. | Wound and skin care compositions |
| US20050003024A1 (en) * | 2003-03-04 | 2005-01-06 | The Procter & Gamble Company | Regulation of mammalian hair growth |
| US20050255059A1 (en) * | 2004-05-10 | 2005-11-17 | Oblong John E | Personal care compositions and methods regulating mammalian hair growth |
| US20050255060A1 (en) * | 2004-05-10 | 2005-11-17 | Oblong John E | Personal care compositions and methods regulating mammalian hair growth |
| US7485666B2 (en) * | 2004-06-17 | 2009-02-03 | Kimberly-Clark Worldwide, Inc. | Vaginal health products |
| US20060269508A1 (en) * | 2005-03-29 | 2006-11-30 | Trejo Amy V | Means for regulating the cosmetic appearance and/or health of human keratinous tissue |
| US9616011B2 (en) | 2005-04-27 | 2017-04-11 | The Procter & Gamble Company | Personal care compositions |
| US20070020220A1 (en) | 2005-04-27 | 2007-01-25 | Procter & Gamble | Personal care compositions |
| US20080095732A1 (en) * | 2005-04-27 | 2008-04-24 | Rosemarie Osborne | Personal care compositions |
| CA2789262C (en) | 2005-04-28 | 2016-10-04 | Proteus Digital Health, Inc. | Pharma-informatics system |
| US20060263321A1 (en) * | 2005-05-17 | 2006-11-23 | The Procter & Gamble Company | Regulation of mammalian keratinous tissue using personal care compositions comprising diethylhexyl syringylidene malonate |
| US20070020221A1 (en) * | 2005-05-17 | 2007-01-25 | Bissett Donald L | Regulation of mammalian keratinous tissue using personal care compositions comprising cetyl pyridinium chloride |
| US20070185038A1 (en) * | 2005-09-30 | 2007-08-09 | The Procter & Gamble Company | Regulation of mammalian keratinous tissue using skin care actives |
| ES2661728T3 (es) | 2005-10-03 | 2018-04-03 | Pinksky, Mark A. | Composiciones y métodos para el cuidado mejorado de la piel |
| US20070134173A1 (en) * | 2005-12-09 | 2007-06-14 | The Procter & Gamble Company | Personal care compositions |
| US20070196296A1 (en) * | 2005-12-13 | 2007-08-23 | Rosemarie Osborne | Personal care compositions |
| EP1971322A2 (de) * | 2005-12-13 | 2008-09-24 | The Procter & Gamble Company | Körperpflegezusammensetzungen mit ppar-gamma-antagonisten |
| US20070203240A1 (en) * | 2006-02-27 | 2007-08-30 | The Procter & Gamble Company | Personal care compositions and methods for regulating mammalian hair growth |
| US20080027575A1 (en) * | 2006-04-21 | 2008-01-31 | Jones Stevan D | Modeling systems for health and beauty consumer goods |
| EP2063905B1 (de) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen |
| CN100475189C (zh) | 2006-10-17 | 2009-04-08 | 王海龙 | 一种化妆品组合物及其制备方法和应用 |
| CN104710365A (zh) | 2008-04-28 | 2015-06-17 | 旭化成制药株式会社 | 苯丙酸衍生物及其用途 |
| US9676696B2 (en) * | 2009-01-29 | 2017-06-13 | The Procter & Gamble Company | Regulation of mammalian keratinous tissue using skin and/or hair care actives |
| TR201908314T4 (tr) | 2009-02-20 | 2019-06-21 | 2 Bbb Medicines B V | Glutatyon bazlı ilaç dağıtım sistemi. |
| KR101909711B1 (ko) | 2009-05-06 | 2018-12-19 | 라보라토리 스킨 케어, 인크. | 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| US8986677B2 (en) | 2012-07-30 | 2015-03-24 | Pop Test Cortisol Llc | Therapeutic compositions and methods |
| US9241891B2 (en) | 2012-10-30 | 2016-01-26 | The Procter & Gamble Company | Personal care compositions comprising self-assembling peptides |
| CN106715463B (zh) | 2013-12-10 | 2020-10-16 | 苏塞克斯研究实验室 | 糖化肽组合物及其用途 |
| US11040037B2 (en) | 2016-10-04 | 2021-06-22 | Pop Test Oncology Llc | Therapeutic agents and methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6019305B2 (ja) * | 1976-07-02 | 1985-05-15 | ウェルファイド株式会社 | ジヒドロベンゾフラン誘導体 |
| IT1093805B (it) * | 1978-01-31 | 1985-07-26 | Erba Carlo Spa | Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione |
| US4533734A (en) * | 1983-11-10 | 1985-08-06 | Eli Lilly And Company | Inotropic agents |
| US4849428A (en) * | 1987-11-23 | 1989-07-18 | The Procter & Gamble Company | Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds, compositions and use |
| JP2808460B2 (ja) * | 1989-11-16 | 1998-10-08 | 大正製薬株式会社 | イミダゾール誘導体 |
| JPH03215485A (ja) * | 1990-01-11 | 1991-09-20 | Taisho Pharmaceut Co Ltd | ベンゾチエニルイミダゾール誘導体 |
| JPH10506615A (ja) * | 1994-07-27 | 1998-06-30 | ザ、プロクター、エンド、ギャンブル、カンパニー | 抗炎症剤として有用なジヒドロベンゾフラン及び関連化合物 |
| US5684002A (en) * | 1994-09-07 | 1997-11-04 | The Procter & Gamble Company | Dihydorbenzofuran and related compounds useful as anti-inflammatory agents |
-
1996
- 1996-02-01 US US08/595,087 patent/US5821250A/en not_active Expired - Fee Related
-
1997
- 1997-01-30 DE DE1997630415 patent/DE69730415T2/de not_active Expired - Fee Related
- 1997-01-30 CN CN97192019A patent/CN1109679C/zh not_active Expired - Fee Related
- 1997-01-30 BR BR9707333A patent/BR9707333A/pt not_active Application Discontinuation
- 1997-01-30 CA CA002244411A patent/CA2244411A1/en not_active Abandoned
- 1997-01-30 JP JP52776197A patent/JP3202245B2/ja not_active Expired - Fee Related
- 1997-01-30 WO PCT/US1997/001313 patent/WO1997028146A1/en not_active Ceased
- 1997-01-30 KR KR1019980705949A patent/KR100322401B1/ko not_active Expired - Fee Related
- 1997-01-30 AT AT97904018T patent/ATE274506T1/de not_active IP Right Cessation
- 1997-01-30 AU AU18432/97A patent/AU730264B2/en not_active Ceased
- 1997-01-30 DK DK97904018T patent/DK0883616T3/da active
- 1997-01-30 EP EP97904018A patent/EP0883616B1/de not_active Expired - Lifetime
- 1997-01-30 ES ES97904018T patent/ES2229332T3/es not_active Expired - Lifetime
-
1998
- 1998-04-09 US US09/058,405 patent/US5972957A/en not_active Expired - Lifetime
- 1998-04-09 US US09/057,686 patent/US5981547A/en not_active Expired - Lifetime
- 1998-07-31 NO NO983529A patent/NO983529L/no not_active Application Discontinuation
- 1998-08-03 MX MX9806248A patent/MX9806248A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69730415D1 (de) | 2004-09-30 |
| CN1210531A (zh) | 1999-03-10 |
| DE69730415T2 (de) | 2005-01-13 |
| JPH11503469A (ja) | 1999-03-26 |
| US5821250A (en) | 1998-10-13 |
| CN1109679C (zh) | 2003-05-28 |
| KR19990082221A (ko) | 1999-11-25 |
| AU730264B2 (en) | 2001-03-01 |
| ES2229332T3 (es) | 2005-04-16 |
| JP3202245B2 (ja) | 2001-08-27 |
| BR9707333A (pt) | 1999-07-20 |
| AU1843297A (en) | 1997-08-22 |
| NO983529D0 (no) | 1998-07-31 |
| DK0883616T3 (da) | 2004-11-01 |
| WO1997028146A1 (en) | 1997-08-07 |
| MX9806248A (es) | 1998-11-30 |
| ATE274506T1 (de) | 2004-09-15 |
| CA2244411A1 (en) | 1997-08-07 |
| KR100322401B1 (ko) | 2002-05-09 |
| EP0883616B1 (de) | 2004-08-25 |
| US5981547A (en) | 1999-11-09 |
| EP0883616A1 (de) | 1998-12-16 |
| US5972957A (en) | 1999-10-26 |
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