PH23620A - Antibiotic a 40926 n-acylaminoglucuronyl aglycons and antibiotic a 40926 aglycon - Google Patents

Antibiotic a 40926 n-acylaminoglucuronyl aglycons and antibiotic a 40926 aglycon

Info

Publication number: PH23620A
Authority: PH; Philippines
Prior art keywords: antibiotic; aglycon; factor; acylaminoglucuronyl; acylaminoglucuronyl aglycon
Prior art date: 1986-04-11

Application number

PH34710A

Other languages

English (en)

Inventor

Enrico Selva

Ernesto Riva

Giovanni Cassani

Francesco Parenti

Original Assignee

Lepetit Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-11

Filing date

1987-01-12

Publication date

1989-09-11

1987-01-12 Application filed by Lepetit Spa filed Critical Lepetit Spa

1989-09-11 Publication of PH23620A publication Critical patent/PH23620A/en

Links

BEVDFPMXVNOQBI-AXNWEOKVSA-N (19R,22R,34S,37R,40R,52S)-64-[(2S,3R,4R,5S,6S)-3-amino-6-carboxy-4,5-dihydroxyoxan-2-yl]oxy-5,32-dichloro-2,26,31,49-tetrahydroxy-22-(methylamino)-21,35,38,54,56,59-hexaoxo-47-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7,13,28-trioxa-20,36,39,53,55,58-hexazaundecacyclo[38.14.2.23,6.214,17.219,34.18,12.123,27.129,33.141,45.010,37.046,51]hexahexaconta-3,5,8,10,12(64),14(63),15,17(62),23(61),24,26,29(60),30,32,41,43,45(57),46(51),47,49,65-henicosaene-52-carboxylic acid Chemical compound CN[C@@H]1c2ccc(O)c(Oc3cc(O)c(Cl)c(c3)[C@@H]3NC(=O)[C@@H](Cc4ccc(Oc5cc6cc(Oc7ccc(cc7Cl)C(O)C7NC(=O)[C@H](NC(=O)[C@@H]6NC3=O)c3cccc(c3)-c3c(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)cc(O)cc3[C@H](NC7=O)C(O)=O)c5O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3N)C(O)=O)cc4)NC1=O)c2 BEVDFPMXVNOQBI-AXNWEOKVSA-N 0.000 title abstract 9
DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 title abstract 7
208000035473 Communicable disease Diseases 0.000 abstract 1
102000003712 Complement factor B Human genes 0.000 abstract 1
108090000056 Complement factor B Proteins 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medicinal Preparation (AREA)

PH34710A 1986-04-11 1987-01-12 Antibiotic a 40926 n-acylaminoglucuronyl aglycons and antibiotic a 40926 aglycon PH23620A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868608809A GB8608809D0 (en)	1986-04-11	1986-04-11	Antibiotic

Publications (1)

Publication Number	Publication Date
PH23620A true PH23620A (en)	1989-09-11

Family

ID=10596024

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH34710A PH23620A (en)	1986-04-11	1987-01-12	Antibiotic a 40926 n-acylaminoglucuronyl aglycons and antibiotic a 40926 aglycon

Country Status (22)

Country	Link
US (1)	US4868171A (de)
EP (1)	EP0240609B1 (de)
JP (1)	JPH0759593B2 (de)
KR (2)	KR950010461B1 (de)
CN (1)	CN1033043C (de)
AT (1)	ATE70069T1 (de)
AU (1)	AU601706B2 (de)
DE (1)	DE3682767D1 (de)
DK (1)	DK167770B1 (de)
ES (1)	ES2040207T3 (de)
FI (1)	FI86307C (de)
GB (1)	GB8608809D0 (de)
GR (1)	GR3003443T3 (de)
HU (1)	HU196229B (de)
IE (1)	IE59523B1 (de)
IL (1)	IL81106A (de)
MY (1)	MY101178A (de)
NO (1)	NO172121C (de)
NZ (1)	NZ218789A (de)
PH (1)	PH23620A (de)
PT (1)	PT84029B (de)
ZA (1)	ZA869713B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK363587A (da) *	1986-07-30	1988-01-31	Smithkline Beckman Corp	Antibiotika og fremstilling heraf under anvendelseaf actinomadura parvosata
GB8621912D0 (en) *	1986-09-11	1986-10-15	Lepetit Spa	Increasing ratio of components of anti-biotic complex
ATE135369T1 (de) *	1988-12-27	1996-03-15	Lepetit Spa	Chemisches verfahren zur herstellung des antibiotikums l 17392 (deglukoteicoplanin) und dessen salze
WO1992010516A1 (en) *	1990-12-05	1992-06-25	Gruppo Lepetit S.P.A.	38-decarboxy-38-hydroxymethyl derivatives of teicoplanin antibiotics, and a process for preparing them
US5606036A (en) *	1991-03-27	1997-02-25	Gruppo Lepetit Spa	Antibiotic A 40926 ester derivatives
DE69215665T2 (de)	1991-03-27	1997-06-12	Gruppo Lepetit S.P.A., Lainate	Esterderivate von antibiotikum-a 40926
US5750509A (en) *	1991-07-29	1998-05-12	Gruppo Lepetit S.P.A.	Amide derivatives of antibiotic A 40926
EP0596929B1 (de) *	1991-07-29	1995-07-26	GRUPPO LEPETIT S.p.A.	Amidderivate vom Antibiotikum A 40926
PT836619E (pt) *	1995-07-05	2004-11-30	Aventis Bulk S P A	Purificacao de antibioticos dalba-heptidicos por focagem isoelectrica
EP0912604B1 (de)	1996-04-23	2001-11-14	Biosearch Italia S.p.A.	Chemisches Verfahren zur Herstellung von Amidderivaten von A 40926 Antibiotikum
US20060074014A1 (en)	2002-11-18	2006-04-06	Vicuron Pharmaceuticals Inc.	Dalbavancin compositions for treatment of bacterial infections
US7119061B2 (en) *	2002-11-18	2006-10-10	Vicuron Pharmaceuticals, Inc.	Dalbavancin compositions for treatment of bacterial infections
MXPA05005338A (es) *	2002-11-18	2005-12-14	Vicuron Pharm Inc	Metodos para administrar dalbavancin para el tratamiento de infecciones bacterianas.
CN101851277B (zh) *	2009-03-12	2012-10-03	成都雅途生物技术有限公司	一种道古霉素关键中间体a40926 bo组分的纯化制备方法
CN102417919B (zh) *	2011-09-02	2017-05-24	山东鲁抗医药股份有限公司	一种发酵法生产高纯度替考拉宁的方法
CN110105435B (zh) *	2019-05-08	2023-12-08	宜昌东阳光生化制药有限公司	一种生产a40926的发酵培养基和发酵方法
CN112625925B (zh) *	2021-01-08	2022-04-19	浙江大学	一种达巴万星前体a40926b0高产菌株及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RO86375A (ro) *	1982-03-24	1985-03-15	Eli Lilly And Co,Us	Procedeu pentru prepararea antibioticului a 41030
GB8307847D0 (en) *	1983-03-22	1983-04-27	Lepetit Spa	Antibiotics l 17054 and l 17046
US4521335A (en) *	1983-07-13	1985-06-04	Smithkline Beckman Corporation	Aglycone and pseudo-aglycones of the AAD 216 antibiotics
AU579120B2 (en) *	1983-12-16	1988-11-17	Gruppo Lepetit S.P.A.	Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
GB8425685D0 (en) *	1984-10-11	1984-11-14	Lepetit Spa	Antibiotic a 40926 complex

1986
- 1986-04-11 GB GB868608809A patent/GB8608809D0/en active Pending
- 1986-12-15 DE DE8686117452T patent/DE3682767D1/de not_active Expired - Lifetime
- 1986-12-15 ES ES198686117452T patent/ES2040207T3/es not_active Expired - Lifetime
- 1986-12-15 AT AT86117452T patent/ATE70069T1/de not_active IP Right Cessation
- 1986-12-15 EP EP86117452A patent/EP0240609B1/de not_active Expired - Lifetime
- 1986-12-19 DK DK617286A patent/DK167770B1/da not_active IP Right Cessation
- 1986-12-23 US US06/945,639 patent/US4868171A/en not_active Expired - Fee Related
- 1986-12-23 IE IE338286A patent/IE59523B1/en not_active IP Right Cessation
- 1986-12-23 NZ NZ218789A patent/NZ218789A/xx unknown
- 1986-12-23 AU AU66883/86A patent/AU601706B2/en not_active Ceased
- 1986-12-26 IL IL81106A patent/IL81106A/xx not_active IP Right Cessation
- 1986-12-29 NO NO865323A patent/NO172121C/no unknown
- 1986-12-29 ZA ZA869713A patent/ZA869713B/xx unknown
- 1986-12-29 JP JP61315965A patent/JPH0759593B2/ja not_active Expired - Lifetime
- 1986-12-29 KR KR1019860011488A patent/KR950010461B1/ko not_active Expired - Fee Related
- 1986-12-29 PT PT84029A patent/PT84029B/pt not_active IP Right Cessation
- 1986-12-29 HU HU865504A patent/HU196229B/hu not_active IP Right Cessation
- 1986-12-29 FI FI865320A patent/FI86307C/fi not_active IP Right Cessation
- 1986-12-30 CN CN86108977A patent/CN1033043C/zh not_active Expired - Fee Related
1987
- 1987-01-12 PH PH34710A patent/PH23620A/en unknown
- 1987-04-01 MY MYPI87000414A patent/MY101178A/en unknown
- 1987-07-01 KR KR1019870006804A patent/KR960010557B1/ko not_active Expired - Fee Related
1991
- 1991-12-27 GR GR91402185T patent/GR3003443T3/el unknown

Also Published As

Publication number	Publication date
HU196229B (en)	1988-10-28
KR890002231A (ko)	1989-04-08
ES2040207T3 (es)	1993-10-16
US4868171A (en)	1989-09-19
AU601706B2 (en)	1990-09-20
KR950010461B1 (ko)	1995-09-18
NZ218789A (en)	1990-09-26
MY101178A (en)	1991-07-31
GB8608809D0 (en)	1986-05-14
DK617286A (da)	1987-10-12
IL81106A0 (en)	1987-03-31
DK167770B1 (da)	1993-12-13
EP0240609A3 (en)	1988-07-27
GR3003443T3 (en)	1993-02-17
IE59523B1 (en)	1994-03-09
AU6688386A (en)	1987-10-15
NO172121C (no)	1993-06-09
ZA869713B (en)	1987-12-30
ATE70069T1 (de)	1991-12-15
NO172121B (no)	1993-03-01
EP0240609A2 (de)	1987-10-14
FI865320A0 (fi)	1986-12-29
DE3682767D1 (de)	1992-01-16
JPS62242699A (ja)	1987-10-23
JPH0759593B2 (ja)	1995-06-28
CN1033043C (zh)	1996-10-16
HUT43869A (en)	1987-12-28
DK617286D0 (da)	1986-12-19
PT84029B (pt)	1989-01-17
KR960010557B1 (ko)	1996-08-02
IL81106A (en)	1992-07-15
FI86307C (fi)	1992-08-10
NO865323L (no)	1987-10-12
IE863382L (en)	1987-10-11
FI865320L (fi)	1987-10-12
PT84029A (en)	1987-01-01
EP0240609B1 (de)	1991-12-04
CN86108977A (zh)	1988-04-27
KR870010194A (ko)	1987-11-30
FI86307B (fi)	1992-04-30

Publication	Publication Date	Title
EP0240609A3 (en)	1988-07-27	Antibiotic a 40926 n-acylaminoglucuronyl aglycons and antibiotic a 40926 aglycon
IE863381L (en)	1987-06-30	Antibiotics
PT85885A (en)	1987-11-01	Process for preparing novel de-acyl a 40926 antibiotics
GR3015052T3 (en)	1995-05-31	Antibiotic GE 2270 factors A1, A2, A3 and H.
GR3015899T3 (en)	1995-07-31	Antibiotic GE 2270 factors B1, B2, C1, C2, D1, D2,E and T.
AU6725387A (en)	1988-06-16	Drugs for the treatment and cure of all infectious diseases caused by pathogenic virulent micro-organisms
IL91427A0 (en)	1990-04-29	Pharmaceutical combination preparations and their use for the prophylaxis or treatment of bacterial infectious diseases