|
ES2629683T3
(es)
|
1999-11-30 |
2017-08-14 |
Mayo Foundation For Medical Education And Research |
B7-H1, una nueva molécula inmunorreguladora
|
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
US7432351B1
(en)
|
2002-10-04 |
2008-10-07 |
Mayo Foundation For Medical Education And Research |
B7-H1 variants
|
|
SI3428191T1
(sl)
|
2004-10-06 |
2025-03-31 |
Mayo Foundation For Medical Education And Research |
B7-H1 in PD-1 v zdravljenju karcinoma ledvičnih celic
|
|
CN103059138B
(zh)
*
|
2005-05-09 |
2015-10-28 |
小野药品工业株式会社 |
程序性死亡-1(pd-1)的人单克隆抗体及使用抗pd-1抗体来治疗癌症的方法
|
|
JP5603012B2
(ja)
|
2005-12-02 |
2014-10-08 |
トヘ モウント シナイ スクール オフ メディシネ オフ ニューヨーク ウニベルシトイ |
非天然表面タンパク質を提示するキメラウイルス及びその使用
|
|
PL2347775T3
(pl)
|
2005-12-13 |
2020-11-16 |
President And Fellows Of Harvard College |
Rusztowania do przeszczepiania komórek
|
|
EP2514762B1
(en)
|
2007-07-13 |
2015-04-08 |
The Johns Hopkins University |
B7-DC variants
|
|
BRPI0917891A2
(pt)
*
|
2008-08-25 |
2015-11-24 |
Amplimmune Inc |
antagonistas de pd-1 e métodos de utilização dos mesmos
|
|
PL2350129T3
(pl)
|
2008-08-25 |
2015-12-31 |
Amplimmune Inc |
Kompozycje antagonistów PD-1 i sposoby stosowania
|
|
NZ717213A
(en)
|
2008-12-09 |
2017-10-27 |
Genentech Inc |
Anti-pd-l1 antibodies and their use to enhance t-cell function
|
|
JP2013512251A
(ja)
*
|
2009-11-24 |
2013-04-11 |
アンプリミューン、インコーポレーテッド |
Pd−l1/pd−l2の同時阻害
|
|
EP2542590B2
(en)
*
|
2010-03-05 |
2020-04-01 |
The Johns Hopkins University |
Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
|
|
US8906374B2
(en)
|
2010-04-20 |
2014-12-09 |
Cedars-Sinai Medical Center |
Combination therapy with CD4 lymphocyte depletion and mTOR inhibitors
|
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
|
US9783578B2
(en)
|
2010-06-25 |
2017-10-10 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
|
WO2012018538A2
(en)
*
|
2010-07-26 |
2012-02-09 |
Schering Corporation |
Bioassays for determining pd-1 modulation
|
|
CA2813751C
(en)
|
2010-10-06 |
2019-11-12 |
President And Fellows Of Harvard College |
Injectable, pore-forming hydrogels for materials-based cell therapies
|
|
CN103261217B
(zh)
*
|
2010-11-11 |
2017-04-26 |
港大科桥有限公司 |
可溶性 pd‑1变体、融合构建体及其用途
|
|
EP2701699B1
(en)
|
2011-04-28 |
2019-10-16 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
US9675561B2
(en)
|
2011-04-28 |
2017-06-13 |
President And Fellows Of Harvard College |
Injectable cryogel vaccine devices and methods of use thereof
|
|
CN102298053B
(zh)
*
|
2011-05-20 |
2014-01-29 |
中山大学肿瘤防治中心 |
原发性肝细胞肝癌术后复发风险评估的组合抗体试剂盒
|
|
EP2717895A1
(en)
*
|
2011-06-08 |
2014-04-16 |
Aurigene Discovery Technologies Limited |
Therapeutic compounds for immunomodulation
|
|
WO2012177788A1
(en)
*
|
2011-06-20 |
2012-12-27 |
La Jolla Institute For Allergy And Immunology |
Modulators of 4-1bb and immune responses
|
|
WO2013003555A1
(en)
|
2011-06-28 |
2013-01-03 |
Whitehead Institute For Biomedical Research |
Using sortases to install click chemistry handles for protein ligation
|
|
WO2013019906A1
(en)
|
2011-08-01 |
2013-02-07 |
Genentech, Inc. |
Methods of treating cancer using pd-1 axis binding antagonists and mek inhibitors
|
|
GB201120527D0
(en)
*
|
2011-11-29 |
2012-01-11 |
Ucl Business Plc |
Method
|
|
CN104427992B
(zh)
*
|
2012-01-25 |
2017-12-19 |
德那翠丝有限公司 |
生物标志物及使用溶瘤病毒和免疫调节剂的组合疗法
|
|
JP6378170B2
(ja)
|
2012-04-12 |
2018-08-22 |
イェール ユニバーシティーYale University |
異なる医薬品の制御送達のためのビヒクル
|
|
PL2838515T3
(pl)
|
2012-04-16 |
2020-06-29 |
President And Fellows Of Harvard College |
Kompozycje mezoporowatego krzemu do modulowania odpowiedzi odpornościowych
|
|
DK3473707T3
(da)
|
2012-05-25 |
2025-03-17 |
Cellectis |
Fremgangsmåder til engineering af allogen og immunsuppressiv resistent t-celle til immunoterapi
|
|
KR102129636B1
(ko)
*
|
2012-05-31 |
2020-07-03 |
제넨테크, 인크. |
Pd-l1 축 결합 길항제 및 vegf 길항제를 사용하여 암을 치료하는 방법
|
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
|
WO2014018979A1
(en)
|
2012-07-27 |
2014-01-30 |
The Broad Institute, Inc. |
Inhibitors of histone deacetylase
|
|
WO2014047350A1
(en)
*
|
2012-09-20 |
2014-03-27 |
Morningside Technology Ventures Ltd. |
Oncolytic virus encoding pd-1 binding agents and uses of the same
|
|
US9597357B2
(en)
|
2012-10-10 |
2017-03-21 |
Sangamo Biosciences, Inc. |
T cell modifying compounds and uses thereof
|
|
US9657082B2
(en)
|
2013-01-31 |
2017-05-23 |
Thomas Jefferson University |
PD-L1 and PD-L2-based fusion proteins and uses thereof
|
|
US20150377891A1
(en)
*
|
2013-02-07 |
2015-12-31 |
(Institute National De La Santé Et De La Rechere Médicale) |
Methods for Predicting the Survival Time of Patients Suffering from Diffuse Large B-Cell Lymphomas
|
|
AU2014218976B2
(en)
|
2013-02-20 |
2018-11-15 |
Novartis Ag |
Treatment of cancer using humanized anti-EGFRvIII chimeric antigen receptor
|
|
WO2014130635A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
|
|
EP3292873B1
(en)
|
2013-02-22 |
2019-05-01 |
CureVac AG |
Combination of vaccination and inhibition of the pd-1 pathway
|
|
DK2958588T3
(da)
|
2013-02-22 |
2017-11-20 |
Curevac Ag |
Kombination af vaccination og hæmning af PD-1-reaktionsvejen
|
|
US20160017011A1
(en)
*
|
2013-02-26 |
2016-01-21 |
Rongfu Wang |
Phf20 and jmjd3 compositions and methods of use in cancer immunotherapy
|
|
US9302005B2
(en)
|
2013-03-14 |
2016-04-05 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
|
MD4655C1
(ro)
|
2013-03-14 |
2020-06-30 |
Icahn School Of Medicine At Mount Sinai |
Virusurile bolii de Newcastle şi utilizarea acestora
|
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
|
MX2015014249A
(es)
|
2013-04-09 |
2016-06-02 |
Lixte Biotechnology Inc |
Formulaciones de oxabicicloheptanos y oxabicicloheptenos.
|
|
CN105339389B
(zh)
|
2013-05-02 |
2021-04-27 |
安奈普泰斯生物有限公司 |
针对程序性死亡-1(pd-1)的抗体
|
|
HK1222662A1
(zh)
|
2013-05-10 |
2017-07-07 |
Whitehead Institute For Biomedical Research |
体外生产具有可分选蛋白的无核红细胞
|
|
US10260038B2
(en)
|
2013-05-10 |
2019-04-16 |
Whitehead Institute For Biomedical Research |
Protein modification of living cells using sortase
|
|
US11077144B2
(en)
|
2013-05-13 |
2021-08-03 |
Cellectis |
CD19 specific chimeric antigen receptor and uses thereof
|
|
US11311575B2
(en)
|
2013-05-13 |
2022-04-26 |
Cellectis |
Methods for engineering highly active T cell for immunotherapy
|
|
WO2014194293A1
(en)
|
2013-05-30 |
2014-12-04 |
Amplimmune, Inc. |
Improved methods for the selection of patients for pd-1 or b7-h4 targeted therapies, and combination therapies thereof
|
|
WO2014205199A2
(en)
*
|
2013-06-22 |
2014-12-24 |
Nitor Therapeutics |
Compositions and methods for potentiating immune response, enhancing immunotherapy, and increasing vaccine potency
|
|
DK3030262T3
(da)
|
2013-08-08 |
2019-12-02 |
Cytune Pharma |
Kombineret farmaceutisk sammensætning
|
|
ES2902589T3
(es)
|
2013-08-08 |
2022-03-29 |
Cytune Pharma |
Modulocinas basadas en el dominio sushi de IL-15 e IL-15R-alfa
|
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
|
PT3508502T
(pt)
|
2013-09-20 |
2023-06-22 |
Bristol Myers Squibb Co |
Combinação de anticorpos anti-lag-3 e anticorpos anti-pd-1 para tratar tumores
|
|
US10570204B2
(en)
|
2013-09-26 |
2020-02-25 |
The Medical College Of Wisconsin, Inc. |
Methods for treating hematologic cancers
|
|
EP3052131B1
(en)
|
2013-10-01 |
2018-12-05 |
Mayo Foundation for Medical Education and Research |
Methods for treating cancer in patients with elevated levels of bim
|
|
US9884026B2
(en)
|
2013-11-01 |
2018-02-06 |
Yale University |
Modular particles for immunotherapy
|
|
WO2015066413A1
(en)
|
2013-11-01 |
2015-05-07 |
Novartis Ag |
Oxazolidinone hydroxamic acid compounds for the treatment of bacterial infections
|
|
EA201690987A1
(ru)
|
2013-11-13 |
2016-10-31 |
Новартис Аг |
Низкодозовые иммуностимулирующие ингибиторы mtor и их применения
|
|
US10556024B2
(en)
|
2013-11-13 |
2020-02-11 |
Whitehead Institute For Biomedical Research |
18F labeling of proteins using sortases
|
|
PE20160953A1
(es)
|
2013-12-12 |
2016-09-26 |
Shanghai hengrui pharmaceutical co ltd |
Anticuerpo pd-1, fragmento de union al antigeno de este y uso medico de este
|
|
WO2015095423A2
(en)
*
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
|
ES2918501T3
(es)
|
2013-12-19 |
2022-07-18 |
Novartis Ag |
Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
|
|
US20170044268A1
(en)
*
|
2013-12-23 |
2017-02-16 |
OncoMed Pharmaceuticals |
Immunotherapy with Binding Agents
|
|
WO2015103645A2
(en)
*
|
2014-01-06 |
2015-07-09 |
Expression Pathology, Inc. |
Srm assay for pd-l1
|
|
WO2015103602A1
(en)
*
|
2014-01-06 |
2015-07-09 |
The Trustees Of The University Of Pennsylvania |
Pd1 and pdl1 antibodies and vaccine combinations and use of same for immunotherapy
|
|
JO3517B1
(ar)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
|
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
|
US9683048B2
(en)
|
2014-01-24 |
2017-06-20 |
Novartis Ag |
Antibody molecules to PD-1 and uses thereof
|
|
ME03489B
(me)
|
2014-01-31 |
2020-01-20 |
Novartis Ag |
Molekuli antitijela na tim-3 i njihove upotrebe
|
|
US11213583B2
(en)
*
|
2014-02-05 |
2022-01-04 |
Cedars-Sinai Medical Center |
Methods and compositions for treating cancer and infectious diseases
|
|
EP3110443A4
(en)
|
2014-02-27 |
2017-11-15 |
Viralytics Limited |
Combination method for treatment of cancer
|
|
JP2017507155A
(ja)
*
|
2014-03-05 |
2017-03-16 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
抗pd−1抗体と他の抗癌剤の組合せを使用する腎癌の処置
|
|
US9394365B1
(en)
|
2014-03-12 |
2016-07-19 |
Yeda Research And Development Co., Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease
|
|
NZ725006A
(en)
|
2014-03-12 |
2019-11-29 |
Yeda Res & Dev |
Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
|
|
ES2754239T3
(es)
|
2014-03-12 |
2020-04-16 |
Curevac Ag |
Combinación de vacunación y agonistas de OX40
|
|
US10618963B2
(en)
|
2014-03-12 |
2020-04-14 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
US10519237B2
(en)
|
2014-03-12 |
2019-12-31 |
Yeda Research And Development Co. Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
|
|
JP6576962B2
(ja)
|
2014-03-14 |
2019-09-18 |
ノバルティス アーゲー |
Lag−3に対する抗体分子およびその使用
|
|
WO2015142675A2
(en)
|
2014-03-15 |
2015-09-24 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
|
PL3122745T3
(pl)
|
2014-03-24 |
2019-08-30 |
Novartis Ag |
Monobaktamowe związki organiczne do leczenia zakażeń bakteryjnych
|
|
KR20160146747A
(ko)
|
2014-03-31 |
2016-12-21 |
제넨테크, 인크. |
항혈관신생제 및 ox40 결합 효능제를 포함하는 조합 요법
|
|
PL3129470T3
(pl)
|
2014-04-07 |
2021-11-29 |
Novartis Ag |
Leczenie nowotworu złośliwego z zastosowaniem chimerycznego receptora antygenowego anty-CD19
|
|
JP7348708B2
(ja)
|
2014-04-30 |
2023-09-21 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
組み合わせワクチン装置および癌細胞を殺滅する方法
|
|
EP3142697A1
(en)
|
2014-05-15 |
2017-03-22 |
Bristol-Myers Squibb Company |
Treatment of lung cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent
|
|
US10302653B2
(en)
|
2014-05-22 |
2019-05-28 |
Mayo Foundation For Medical Education And Research |
Distinguishing antagonistic and agonistic anti B7-H1 antibodies
|
|
MA47849A
(fr)
|
2014-05-28 |
2020-01-29 |
Agenus Inc |
Anticorps anti-gitr et leurs procédés d'utilisation
|
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
AR101210A1
(es)
|
2014-07-15 |
2016-11-30 |
Genentech Inc |
Métodos de tratamiento de cáncer usando antagonistas de unión al eje pd-1 e inhibidores de mek
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
CN107109419B
(zh)
|
2014-07-21 |
2020-12-22 |
诺华股份有限公司 |
使用cd33嵌合抗原受体治疗癌症
|
|
WO2016014148A1
(en)
|
2014-07-23 |
2016-01-28 |
Mayo Foundation For Medical Education And Research |
Targeting dna-pkcs and b7-h1 to treat cancer
|
|
US20170209492A1
(en)
|
2014-07-31 |
2017-07-27 |
Novartis Ag |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
JP2017523213A
(ja)
|
2014-08-06 |
2017-08-17 |
ノバルティス アーゲー |
抗菌薬としてのキノロン誘導体
|
|
AU2015300006B2
(en)
*
|
2014-08-07 |
2018-08-30 |
Haruki Okamura |
Therapeutic agent for cancer which comprises combination of IL-18 and molecule-targeting antibody
|
|
PL3177640T3
(pl)
*
|
2014-08-08 |
2020-11-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Charakteryzujące się wysokim powinowactwem środki terapeutyczne naśladujące PD-11 i sposoby ich wykorzystania
|
|
CA2958200A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using a gfr alpha-4 chimeric antigen receptor
|
|
LT3183268T
(lt)
|
2014-08-19 |
2020-06-10 |
Novartis Ag |
Anti-cd123 chimerinis antigeno receptorius (car), skirtas naudoti vėžio gydymui
|
|
EP3191126B1
(en)
|
2014-09-13 |
2020-05-13 |
Novartis AG |
Combination therapies of alk inhibitors
|
|
EP4368205A1
(en)
*
|
2014-09-16 |
2024-05-15 |
Innate Pharma |
Neutralization of inhibitory pathways in lymphocytes
|
|
CA2961636A1
(en)
|
2014-09-17 |
2016-03-24 |
Boris ENGELS |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
US9616114B1
(en)
|
2014-09-18 |
2017-04-11 |
David Gordon Bermudes |
Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
|
|
US10053683B2
(en)
|
2014-10-03 |
2018-08-21 |
Whitehead Institute For Biomedical Research |
Intercellular labeling of ligand-receptor interactions
|
|
KR20170066546A
(ko)
|
2014-10-03 |
2017-06-14 |
노파르티스 아게 |
조합 요법
|
|
JP6815992B2
(ja)
|
2014-10-08 |
2021-01-20 |
ノバルティス アーゲー |
キメラ抗原受容体療法に対する治療応答性を予測するバイオマーカーおよびその使用
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
EP3206711B1
(en)
|
2014-10-14 |
2023-05-31 |
Novartis AG |
Antibody molecules to pd-l1 and uses thereof
|
|
SG11201703326SA
(en)
*
|
2014-10-24 |
2017-05-30 |
Aladar Szalay |
Combination immunotherapy approach for treatment of cancer
|
|
HRP20210440T1
(hr)
|
2014-10-29 |
2021-04-30 |
Five Prime Therapeutics, Inc. |
Kombinirana terapija za rak
|
|
EP4046656A1
(en)
*
|
2014-11-06 |
2022-08-24 |
HiberCell, Inc. |
Beta-glucan methods and compositions that affect the tumor microenvironment
|
|
KR20220054710A
(ko)
|
2014-11-13 |
2022-05-03 |
더 존스 홉킨스 유니버시티 |
관문 차단 및 미소부수체 불안정성
|
|
AU2015347015B2
(en)
|
2014-11-14 |
2019-02-14 |
Novartis Ag |
Antibody drug conjugates
|
|
MX2017007321A
(es)
*
|
2014-12-02 |
2017-08-25 |
Celgene Corp |
Terapias de combinacion.
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
WO2016094273A1
(en)
|
2014-12-08 |
2016-06-16 |
Dana-Farber Cancer Institute, Inc. |
Methods for upregulating immune responses using combinations of anti-rgmb and anti-pd-1 agents
|
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
|
RU2726996C1
(ru)
*
|
2014-12-16 |
2020-07-17 |
Бристол-Маерс Сквибб Компани |
Применение ингибиторов иммунных контрольных точек при новообразованиях центральной нервной системы
|
|
SMT201900631T1
(it)
|
2014-12-16 |
2020-01-14 |
Novartis Ag |
Composti di acido isossazol idrossammico come inibitori di lpxc”
|
|
WO2016100882A1
(en)
|
2014-12-19 |
2016-06-23 |
Novartis Ag |
Combination therapies
|
|
CN105983097B
(zh)
*
|
2015-01-28 |
2021-06-08 |
华中科技大学同济医学院附属协和医院 |
一种抗肿瘤制剂及其制备方法
|
|
HK1247861A1
(zh)
*
|
2015-01-30 |
2018-10-05 |
President And Fellows Of Harvard College |
用於癌症治疗的肿瘤周围和肿瘤内部材料
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
IL292578A
(en)
*
|
2015-02-13 |
2022-06-01 |
Sorrento Therapeutics Inc |
Antibody therapeutics that bind ctla4
|
|
BR112017018234A2
(pt)
*
|
2015-02-26 |
2018-04-17 |
Merck Patent Gmbh |
inibidores de pd-1 / pd-l1 para o tratamento de câncer
|
|
EP3268035A4
(en)
|
2015-03-10 |
2018-10-31 |
Aduro Biotech, Inc. |
Compositions and methods for activating "stimulator of interferon gene" -dependent signalling
|
|
ES2768784T3
(es)
|
2015-03-23 |
2020-06-23 |
Bayer Pharma AG |
Anticuerpos anti-CEACAM6 y usos de los mismos
|
|
ES2876974T3
(es)
|
2015-04-07 |
2021-11-15 |
Novartis Ag |
Combinación de terapia con receptor de antígeno quimérico y derivados de amino pirimidina
|
|
WO2016164705A1
(en)
|
2015-04-10 |
2016-10-13 |
Omar Abdel-Rahman Ali |
Immune cell trapping devices and methods for making and using the same
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
US11896614B2
(en)
|
2015-04-17 |
2024-02-13 |
Novartis Ag |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
EA201792273A1
(ru)
|
2015-04-17 |
2018-04-30 |
Бристол-Маерс Сквибб Компани |
Композиции, содержащие комбинацию анти-pd-1 антитела и другого антитела
|
|
HUE054616T2
(hu)
|
2015-04-17 |
2021-09-28 |
Alpine Immune Sciences Inc |
Immunmodulátor fehérjék hangolható affinitásokkal
|
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
KR20170140316A
(ko)
|
2015-04-28 |
2017-12-20 |
브리스톨-마이어스 스큅 컴퍼니 |
항-pd-1 항체를 사용한 pd-l1-양성 흑색종의 치료
|
|
KR20240149980A
(ko)
|
2015-04-28 |
2024-10-15 |
브리스톨-마이어스 스큅 컴퍼니 |
항-pd-1 항체 및 항-ctla-4 항체를 사용한 pd-l1-음성 흑색종의 치료
|
|
US10676723B2
(en)
|
2015-05-11 |
2020-06-09 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
|
KR20190080992A
(ko)
|
2015-05-21 |
2019-07-08 |
하푼 테라퓨틱스, 인크. |
삼중특이성 결합 단백질 및 사용 방법
|
|
US20180155429A1
(en)
|
2015-05-28 |
2018-06-07 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
|
KR20230028478A
(ko)
|
2015-05-29 |
2023-02-28 |
아게누스 인코포레이티드 |
항-ctla-4 항체 및 이의 사용 방법
|
|
US11078278B2
(en)
|
2015-05-29 |
2021-08-03 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
|
TWI870335B
(zh)
|
2015-06-12 |
2025-01-21 |
美商宏觀基因股份有限公司 |
變異的嵌合4d5抗體及其與抗pd-1抗體聯合用於治療癌症的應用
|
|
US20190194315A1
(en)
|
2015-06-17 |
2019-06-27 |
Novartis Ag |
Antibody drug conjugates
|
|
EA201890285A1
(ru)
*
|
2015-07-13 |
2018-08-31 |
Сайтомкс Терапьютикс, Инк. |
Антитела против pd-1, активируемые антитела против pd-1 и способы их применения
|
|
PT3322731T
(pt)
|
2015-07-14 |
2021-02-25 |
Bristol Myers Squibb Co |
Método de tratamento de cancro utilizando inibidor de ponto de verificação (checkpoint) imunitário; anticorpo que se liga ao recetor de morte programada-1 (pd-1) ou ligando de morte programada 1 (pd-l1)
|
|
AU2016293674B2
(en)
|
2015-07-16 |
2019-11-21 |
Bioxcel Therapeutics, Inc. |
A novel approach for treatment of cancer using immunomodulation
|
|
EP3322431A2
(en)
|
2015-07-16 |
2018-05-23 |
Biokine Therapeutics Ltd. |
Compositions and methods for treating cancer
|
|
SG10201912978PA
(en)
|
2015-07-21 |
2020-02-27 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
|
WO2017019896A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
BR112018000212A2
(pt)
|
2015-07-29 |
2018-09-04 |
Novartis Ag |
uso combinado de anticorpos anti pd-1 e anti m-csf no tratamento de câncer
|
|
WO2017019897A1
(en)
|
2015-07-29 |
2017-02-02 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
EP3317301B1
(en)
|
2015-07-29 |
2021-04-07 |
Novartis AG |
Combination therapies comprising antibody molecules to lag-3
|
|
BR112018001640A2
(pt)
|
2015-07-29 |
2018-09-18 |
Novartis Ag |
combinação de antagonista da pd-1 com um inibidor de egfr
|
|
MA58293B1
(fr)
|
2015-07-30 |
2024-11-29 |
Macrogenics, Inc. |
Molécules de liaison pd-1 et leurs procédés d'utilisation
|
|
HK1254976A1
(zh)
|
2015-07-31 |
2019-08-02 |
University Of Florida Research Foundation, Inc. |
造血干细胞和抗癌免疫检查点抑制剂的组合疗法
|
|
RU2018107991A
(ru)
|
2015-08-07 |
2019-09-09 |
ПИЕРИС ФАРМАСЬЮТИКАЛС ГмбХ |
Новый слитый полипептид, специфичный в отношении lag-3 и pd-1
|
|
KR102114562B1
(ko)
|
2015-08-11 |
2020-05-26 |
노파르티스 아게 |
암의 치료에 사용하기 위한 5-브로모-2,6-디-(1h-피라졸-1-일)피리미딘-4-아민
|
|
EA201800148A1
(ru)
|
2015-08-11 |
2019-01-31 |
Калиди Биотерапьютикс, Инк. |
Оспенная вакцина для лечения рака
|
|
JP6905163B2
(ja)
|
2015-09-03 |
2021-07-21 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
サイトカイン放出症候群を予測するバイオマーカー
|
|
MX390633B
(es)
|
2015-09-14 |
2025-03-04 |
Infinity Pharmaceuticals Inc |
Formas solidas de derivados de isoquinolinona, proceso de fabricacion, composiciones que las contienen y metodos de uso de las mismas.
|
|
ES2941968T3
(es)
|
2015-10-01 |
2023-05-29 |
The Whitehead Institute For Biomedical Res |
Marcaje de anticuerpos
|
|
RS62450B1
(sr)
|
2015-10-02 |
2021-11-30 |
Hoffmann La Roche |
Anti-pd1 antitela i postupci primene
|
|
MY192202A
(en)
|
2015-10-02 |
2022-08-06 |
Hoffmann La Roche |
Bispecific antibodies specific for pd1 and tim3
|
|
GEAP202114756A
(en)
|
2015-10-08 |
2021-07-26 |
Macrogenics Inc |
Combination therapy for the treatment of cancer
|
|
US11207393B2
(en)
|
2015-10-16 |
2021-12-28 |
President And Fellows Of Harvard College |
Regulatory T cell PD-1 modulation for regulating T cell effector immune responses
|
|
ES2994611T3
(en)
|
2015-10-19 |
2025-01-27 |
Cg Oncology Inc |
Methods of treating solid or lymphatic tumors by combination therapy
|
|
EP3368092B9
(en)
|
2015-10-29 |
2020-07-29 |
Novartis AG |
Antibody conjugates comprising toll-like receptor agonist
|
|
US10875923B2
(en)
|
2015-10-30 |
2020-12-29 |
Mayo Foundation For Medical Education And Research |
Antibodies to B7-H1
|
|
CR20180306A
(es)
|
2015-11-02 |
2018-10-16 |
Five Prime Therapeutics Inc |
Polipéptidos del dominio extracelular de cd80 y su uso en el tratamiento del cáncer
|
|
US11702477B2
(en)
|
2015-11-06 |
2023-07-18 |
Orionis Biosciences BV |
Bi-functional chimeric proteins and uses thereof
|
|
PT3377534T
(pt)
|
2015-11-18 |
2025-07-10 |
Bristol Myers Squibb Co |
Tratamento do cancro do pulmão utilizando uma combinação de um anticorpo anti-pd-1 e de um anticorpo anti-ctla-4
|
|
JP7349787B2
(ja)
|
2015-11-23 |
2023-09-25 |
ファイヴ プライム セラピューティクス インク |
癌治療におけるfgfr2阻害剤単独または免疫刺激剤との組み合わせ
|
|
WO2017096179A1
(en)
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
US10590169B2
(en)
*
|
2015-12-09 |
2020-03-17 |
Virogin Biotech Canada Ltd |
Compositions and methods for inhibiting CD279 interactions
|
|
CN108367069B
(zh)
|
2015-12-14 |
2022-08-23 |
宏观基因有限公司 |
对于pd-1和ctla-4具有免疫反应性的双特异性分子及其使用方法
|
|
EP4424322A3
(en)
|
2015-12-17 |
2025-04-16 |
Novartis AG |
Antibody molecules to pd-1 and uses thereof
|
|
US10392442B2
(en)
|
2015-12-17 |
2019-08-27 |
Bristol-Myers Squibb Company |
Use of anti-PD-1 antibody in combination with anti-CD27 antibody in cancer treatment
|
|
US20170198040A1
(en)
|
2015-12-18 |
2017-07-13 |
Novartis Ag |
ANTIBODIES TARGETING CD32b AND METHODS OF USE THEREOF
|
|
PT3393504T
(pt)
|
2015-12-22 |
2025-12-30 |
Novartis Ag |
Recetor de antigénio quimérico (car) de mesotelina e anticorpo contra o inibidor de pd-l1 para utilização combinada em terapia anticancerígena
|
|
LT3394103T
(lt)
|
2015-12-22 |
2023-09-11 |
Regeneron Pharmaceuticals, Inc. |
Antikūnų prieš pd-1 ir bispecifinių antikūnų prieš cd20/cd3 derinys, skirtas vėžiui gydyti
|
|
EP4039699A1
(en)
|
2015-12-23 |
2022-08-10 |
ModernaTX, Inc. |
Methods of using ox40 ligand encoding polynucleotides
|
|
EP3403091B1
(en)
|
2016-01-11 |
2021-12-22 |
Technion Research & Development Foundation Limited |
Methods of determining prognosis of sepsis and treating same
|
|
HK1257518A1
(zh)
|
2016-01-11 |
2019-10-25 |
Novartis Ag |
针对人白介素-2的免疫刺激性人源化单克隆抗体及其融合蛋白
|
|
CN108883180B
(zh)
|
2016-02-05 |
2023-07-07 |
奥里尼斯生物科学私人有限公司 |
Clec9a结合剂及其用途
|
|
CN109072197A
(zh)
|
2016-02-06 |
2018-12-21 |
哈佛学院校长同事会 |
重塑造血巢以重建免疫
|
|
US9845325B2
(en)
|
2016-02-19 |
2017-12-19 |
Novartis Ag |
Tetracyclic pyridone compounds as antivirals
|
|
CN114395624A
(zh)
|
2016-02-29 |
2022-04-26 |
基因泰克公司 |
用于癌症的治疗和诊断方法
|
|
AU2017225869A1
(en)
|
2016-02-29 |
2018-09-06 |
Foundation Medicine, Inc. |
Methods of treating cancer
|
|
JP2019513347A
(ja)
|
2016-03-04 |
2019-05-30 |
ノバルティス アーゲー |
複数のキメラ抗原受容体(car)分子を発現する細胞およびその使用
|
|
WO2017155981A1
(en)
|
2016-03-07 |
2017-09-14 |
Massachusetts Institute Of Technology |
Protein-chaperoned t-cell vaccines
|
|
CN108778301A
(zh)
|
2016-03-10 |
2018-11-09 |
永恒生物科技股份有限公司 |
通过联合疗法来治疗实体瘤或淋巴瘤的方法
|
|
JP2019512271A
(ja)
|
2016-03-21 |
2019-05-16 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
T細胞疲弊状態特異的遺伝子発現調節因子およびその使用
|
|
FI3433257T3
(fi)
|
2016-03-24 |
2024-01-08 |
Novartis Ag |
Alkynyylinukleosidianalogeja ihmisen rinoviruksen estäjinä
|
|
US11209441B2
(en)
|
2016-04-05 |
2021-12-28 |
Bristol-Myers Squibb Company |
Cytokine profiling analysis
|
|
CA3056374A1
(en)
|
2016-04-13 |
2017-10-19 |
Orimabs Ltd. |
Anti-psma antibodies and use thereof
|
|
IL262359B
(en)
|
2016-04-13 |
2022-09-01 |
Vivia Biotech Sl |
In vitro bite-activated T cells
|
|
MA43552A
(fr)
|
2016-04-15 |
2018-11-07 |
Alpine Immune Sciences Inc |
Protéines immunomodulatrices à variants de cd80 et leurs utilisations
|
|
EP3243832A1
(en)
|
2016-05-13 |
2017-11-15 |
F. Hoffmann-La Roche AG |
Antigen binding molecules comprising a tnf family ligand trimer and pd1 binding moiety
|
|
CA3023883A1
(en)
|
2016-05-13 |
2017-11-16 |
Orionis Biosciences Nv |
Targeted mutant interferon-beta and uses thereof
|
|
TWI755395B
(zh)
|
2016-05-13 |
2022-02-21 |
美商再生元醫藥公司 |
抗-pd-1抗體與輻射治療癌症之組合
|
|
EP3455245A2
(en)
|
2016-05-13 |
2019-03-20 |
Orionis Biosciences NV |
Therapeutic targeting of non-cellular structures
|
|
RS63912B1
(sr)
|
2016-05-18 |
2023-02-28 |
Modernatx Inc |
Polinukleotidi koji kodiraju interleukin-12 (il12) i njihove upotrebe
|
|
WO2017201352A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Mrna combination therapy for the treatment of cancer
|
|
EP3458474B1
(en)
|
2016-05-18 |
2022-07-06 |
ModernaTX, Inc. |
Combinations of mrnas encoding immune modulating polypeptides and uses thereof
|
|
EP3493844A4
(en)
|
2016-05-20 |
2021-03-24 |
Harpoon Therapeutics Inc. |
SINGLE DOMAIN SERUM ALBUMIN BINDING PROTEIN
|
|
BR112018073673A2
(pt)
|
2016-05-20 |
2019-02-26 |
Eli Lilly And Company |
terapia de combinação com inibidores de notch e de pd-1 ou pd-l1
|
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
|
TWI781934B
(zh)
|
2016-05-27 |
2022-11-01 |
美商艾吉納斯公司 |
抗-tim-3抗體及其使用方法
|
|
NZ748650A
(en)
|
2016-06-02 |
2025-11-28 |
Bristol Myers Squibb Co |
Use of an anti-pd-1 antibody in combination with an anti-cd30 antibody in lymphoma treatment
|
|
LT3463457T
(lt)
|
2016-06-02 |
2023-09-11 |
Bristol-Myers Squibb Company |
Pd-1 blokada su nivolumabu gydant atsparią hodžkino limfomą
|
|
US20190292260A1
(en)
|
2016-06-03 |
2019-09-26 |
Bristol-Myers Squibb Company |
Anti-pd-1 antibody for use in a method of treatment of recurrent small cell lung cancer
|
|
KR20190015408A
(ko)
|
2016-06-03 |
2019-02-13 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법에 사용하기 위한 항-pd-1 항체
|
|
WO2017210637A1
(en)
|
2016-06-03 |
2017-12-07 |
Bristol-Myers Squibb Company |
Use of anti-pd-1 antibody in the treatment of patients with colorectal cancer
|
|
CN109311828A
(zh)
|
2016-06-14 |
2019-02-05 |
诺华股份有限公司 |
作为抗菌剂的(r)-4-(5-(环丙基乙炔基)异噁唑-3-基)-n-羟基-2-甲基-2-(甲基磺酰基)丁酰胺的结晶形式
|
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
|
SG10201912456RA
(en)
|
2016-06-24 |
2020-02-27 |
Infinity Pharmaceuticals Inc |
Combination therapies
|
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
|
MA45738A
(fr)
|
2016-07-13 |
2019-05-22 |
Harvard College |
Échafaudages mimétiques de cellules présentant l'antigène et procédés pour les préparer et les utiliser
|
|
KR102565885B1
(ko)
|
2016-07-20 |
2023-08-09 |
유니버시티 오브 유타 리서치 파운데이션 |
Cd229 car t 세포 및 이의 사용 방법
|
|
CA3032054A1
(en)
*
|
2016-07-28 |
2018-02-01 |
Novartis Ag |
Combination therapies of chimeric antigen receptors and pd-1 inhibitors
|
|
CN109562282A
(zh)
|
2016-07-29 |
2019-04-02 |
伊莱利利公司 |
用于治疗癌症的使用merestinib和抗-pd-l1或抗-pd-1抑制剂的组合疗法
|
|
EP3490548A4
(en)
|
2016-08-01 |
2020-04-15 |
Molecular Templates, Inc. |
ADMINISTRATION OF HYPOXY-ACTIVATED PRODRUGS IN COMBINATION WITH IMMUNO MODULATORS FOR TREATING CANCER
|
|
IL264557B2
(en)
|
2016-08-02 |
2024-01-01 |
Harvard College |
Biological agents for regulating immune responses
|
|
KR20190044070A
(ko)
|
2016-08-03 |
2019-04-29 |
넥스트큐어 인코포레이티드 |
Lair 신호 변환을 조정하기 위한 조성물 및 방법
|
|
JP2019528689A
(ja)
*
|
2016-08-11 |
2019-10-17 |
ザ カウンシル オブ ザ クイーンズランド インスティテュート オブ メディカル リサーチ |
免疫調節化合物
|
|
US11382953B2
(en)
*
|
2016-08-26 |
2022-07-12 |
Tetsuji Okuno |
Microvascular blood flow decreasing agent and use thereof
|
|
EP3509604B1
(en)
|
2016-09-07 |
2026-02-18 |
Trustees of Tufts College |
Combination therapies using immuno-dash inhibitors and pge2 antagonists
|
|
MX2019002728A
(es)
|
2016-09-09 |
2019-08-16 |
Tg Therapeutics Inc |
Combinacion de un anticuerpo anti-cd20, inhibidor de quinasa pi3-delta, y anticuerpo anti-pd-1 o anti-pd-l1 para el tratamiento hematologico de los canceres.
|
|
WO2018047109A1
(en)
|
2016-09-09 |
2018-03-15 |
Novartis Ag |
Polycyclic pyridone compounds as antivirals
|
|
US20190218294A1
(en)
|
2016-09-09 |
2019-07-18 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-mesothelin antibody in cancer treatment
|
|
HRP20201993T1
(hr)
*
|
2016-09-14 |
2021-02-05 |
Abbvie Biotherapeutics Inc. |
Protutijela protiv pd-1
|
|
US11077178B2
(en)
|
2016-09-21 |
2021-08-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptor (CAR) that targets chemokine receptor CCR4 and its use
|
|
WO2018057735A1
(en)
|
2016-09-21 |
2018-03-29 |
Nextcure, Inc. |
Antibodies for siglec-15 and methods of use thereof
|
|
EP4360714A3
(en)
|
2016-09-21 |
2024-07-24 |
Nextcure, Inc. |
Antibodies for siglec-15 and methods of use thereof
|
|
WO2018057955A1
(en)
|
2016-09-23 |
2018-03-29 |
Elstar Therapeutics, Inc. |
Multispecific antibody molecules comprising lambda and kappa light chains
|
|
JOP20190061A1
(ar)
|
2016-09-28 |
2019-03-26 |
Novartis Ag |
مثبطات بيتا-لاكتاماز
|
|
CN117866991A
(zh)
|
2016-10-07 |
2024-04-12 |
诺华股份有限公司 |
用于治疗癌症的嵌合抗原受体
|
|
MA46529A
(fr)
|
2016-10-11 |
2019-08-21 |
Agenus Inc |
Anticorps anti-lag-3 et leurs procédés d'utilisation
|
|
WO2018071576A1
(en)
|
2016-10-14 |
2018-04-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Treatment of tumors by inhibition of cd300f
|
|
WO2018073753A1
(en)
|
2016-10-18 |
2018-04-26 |
Novartis Ag |
Fused tetracyclic pyridone compounds as antivirals
|
|
ES2917000T3
(es)
|
2016-10-24 |
2022-07-06 |
Orionis Biosciences BV |
Interferón-gamma mutante diana y usos del mismo
|
|
WO2018077629A1
(en)
*
|
2016-10-27 |
2018-05-03 |
Herlev Hospital |
New pdl2 compounds
|
|
CA3041684C
(en)
|
2016-11-01 |
2023-09-26 |
Anaptysbio, Inc. |
Antibodies directed against programmed death- 1 (pd-1)
|
|
HUE057559T2
(hu)
|
2016-11-02 |
2022-06-28 |
Jounce Therapeutics Inc |
PD-1 elleni antitestek és alkalmazásaik
|
|
KR102687833B1
(ko)
|
2016-11-02 |
2024-07-24 |
브리스톨-마이어스 스큅 컴퍼니 |
다발성 골수종 치료를 위한 bcma 및 cd3에 대응하는 이중 특이적 항체 및 면역학적 약물의 복합용도
|
|
TW201825119A
(zh)
|
2016-11-30 |
2018-07-16 |
日商協和醱酵麒麟有限公司 |
使用抗ccr4抗體及抗pd-1抗體治療癌症之方法
|
|
CN110248678A
(zh)
|
2016-12-03 |
2019-09-17 |
朱诺治疗学股份有限公司 |
调节car-t细胞的方法
|
|
JP6992068B2
(ja)
|
2016-12-07 |
2022-02-03 |
アジェナス インコーポレイテッド |
抗ctla-4抗体およびそれらの使用方法
|
|
US11180535B1
(en)
|
2016-12-07 |
2021-11-23 |
David Gordon Bermudes |
Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
|
|
PE20190921A1
(es)
|
2016-12-07 |
2019-06-26 |
Agenus Inc |
Anticuerpos y metodos de su utilizacion
|
|
AU2017370731B2
(en)
|
2016-12-08 |
2022-06-02 |
Lixte Biotechnology, Inc. |
Oxabicycloheptanes for modulation of immune response
|
|
CN110382545A
(zh)
|
2017-01-09 |
2019-10-25 |
泰萨罗公司 |
用抗pd-1抗体治疗癌症的方法
|
|
EP3565560B1
(en)
|
2017-01-09 |
2024-05-29 |
OnkosXcel Therapeutics, LLC |
Predictive and diagnostic methods for prostate cancer
|
|
JP2020503883A
(ja)
|
2017-01-13 |
2020-02-06 |
アジェナス インコーポレイテッド |
Ny−eso−1に結合するt細胞受容体およびその使用方法
|
|
WO2018134279A1
(en)
|
2017-01-18 |
2018-07-26 |
Pieris Pharmaceuticals Gmbh |
Novel fusion polypeptides specific for lag-3 and pd-1
|
|
US20200237874A1
(en)
|
2017-01-20 |
2020-07-30 |
Novartis Ag |
Combination therapy for the treatment of cancer
|
|
TW202506185A
(zh)
|
2017-01-20 |
2025-02-16 |
法商賽諾菲公司 |
抗TGF-β抗體及其用途
|
|
AR110755A1
(es)
|
2017-01-20 |
2019-05-02 |
Genzyme Corp |
Anticuerpos dirigidos a hueso
|
|
JOP20190187A1
(ar)
|
2017-02-03 |
2019-08-01 |
Novartis Ag |
مترافقات عقار جسم مضاد لـ ccr7
|
|
US10906985B2
(en)
|
2017-02-06 |
2021-02-02 |
Orionis Biosciences, Inc. |
Targeted engineered interferon and uses thereof
|
|
MX2019009255A
(es)
|
2017-02-06 |
2019-11-05 |
Orionis Biosciences Nv |
Proteínas quiméricas dirigidas y sus usos.
|
|
WO2018151820A1
(en)
|
2017-02-16 |
2018-08-23 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
|
IL308805B2
(en)
|
2017-02-21 |
2025-12-01 |
Regeneron Pharma |
Anti-PD-1 antibodies for the treatment of lung cancer
|
|
AU2018224094B2
(en)
|
2017-02-24 |
2025-04-17 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof
|
|
CN110337305A
(zh)
|
2017-02-28 |
2019-10-15 |
赛诺菲 |
治疗性rna
|
|
US11179413B2
(en)
|
2017-03-06 |
2021-11-23 |
Novartis Ag |
Methods of treatment of cancer with reduced UBB expression
|
|
EP3596469A1
(en)
|
2017-03-12 |
2020-01-22 |
Yeda Research and Development Co., Ltd. |
Methods of diagnosing and prognosing cancer
|
|
WO2018167780A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of prognosing and treating cancer
|
|
IL268781B2
(en)
|
2017-03-16 |
2025-09-01 |
Alpine Immune Sciences Inc |
Cd80 variant immunomodulatory proteins and uses thereof
|
|
EP3601353A1
(en)
|
2017-03-31 |
2020-02-05 |
Five Prime Therapeutics, Inc. |
Combination therapy for cancer using anti-gitr antibodies
|
|
KR102461885B1
(ko)
|
2017-04-03 |
2022-11-03 |
에프. 호프만-라 로슈 아게 |
항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체
|
|
WO2018185618A1
(en)
|
2017-04-03 |
2018-10-11 |
Novartis Ag |
Anti-cdh6 antibody drug conjugates and anti-gitr antibody combinations and methods of treatment
|
|
US11285207B2
(en)
|
2017-04-05 |
2022-03-29 |
Hoffmann-La Roche Inc. |
Bispecific antibodies specifically binding to PD1 and LAG3
|
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
TW202500588A
(zh)
|
2017-04-13 |
2025-01-01 |
美商艾吉納斯公司 |
抗cd137抗體及其使用方法
|
|
CN110709422B
(zh)
|
2017-04-19 |
2023-12-26 |
马伦戈治疗公司 |
多特异性分子及其用途
|
|
WO2018193104A1
(en)
|
2017-04-20 |
2018-10-25 |
Adc Therapeutics Sa |
Combination therapy with an anti-cd25 antibody-drug conjugate
|
|
MX2019012464A
(es)
|
2017-04-20 |
2019-12-11 |
Adc Therapeutics Sa |
Terapia combinada con un conjugado de anticuerpo y farmaco anti-axl.
|
|
AR111419A1
(es)
|
2017-04-27 |
2019-07-10 |
Novartis Ag |
Compuestos fusionados de indazol piridona como antivirales
|
|
US20200179511A1
(en)
|
2017-04-28 |
2020-06-11 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
ES2899616T3
(es)
|
2017-04-28 |
2022-03-14 |
Five Prime Therapeutics Inc |
Polipéptidos del dominio extracelular del CD80 para su uso en aumentar los linfocitos T de memoria central
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
EP3615566B1
(en)
|
2017-04-28 |
2023-12-20 |
Marengo Therapeutics, Inc. |
Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
MA50957A
(fr)
|
2017-05-01 |
2020-10-14 |
Agenus Inc |
Anticorps anti-tigit et leurs méthodes d'utilisation
|
|
UY37718A
(es)
|
2017-05-05 |
2018-11-30 |
Novartis Ag |
2-quinolinonas triciclicas como agentes antibacteriales
|
|
CN121159691A
(zh)
|
2017-05-12 |
2025-12-19 |
哈普恩治疗公司 |
间皮素结合蛋白质
|
|
JOP20190256A1
(ar)
|
2017-05-12 |
2019-10-28 |
Icahn School Med Mount Sinai |
فيروسات داء نيوكاسل واستخداماتها
|
|
US11685787B2
(en)
|
2017-05-16 |
2023-06-27 |
Bristol-Myers Squibb Company |
Treatment of cancer with anti-GITR agonist antibodies
|
|
JP7285220B2
(ja)
|
2017-05-18 |
2023-06-01 |
モデルナティエックス インコーポレイテッド |
連結したインターロイキン-12(il12)ポリペプチドをコードするポリヌクレオチドを含む脂質ナノ粒子
|
|
CN111107868A
(zh)
|
2017-05-24 |
2020-05-05 |
诺华股份有限公司 |
抗体细胞因子移植蛋白及使用方法
|
|
JP7791642B2
(ja)
|
2017-05-24 |
2025-12-24 |
ノバルティス アーゲー |
抗体-サイトカイングラフト化タンパク質及び癌の治療における使用方法
|
|
WO2018215937A1
(en)
|
2017-05-24 |
2018-11-29 |
Novartis Ag |
Interleukin-7 antibody cytokine engrafted proteins and methods of use in the treatment of cancer
|
|
PL3631454T3
(pl)
|
2017-05-30 |
2024-01-29 |
Bristol-Myers Squibb Company |
Leczenie guzów lag-3 pozytywnych
|
|
CN110691795A
(zh)
|
2017-05-30 |
2020-01-14 |
百时美施贵宝公司 |
包含抗-lag3抗体、pd-1途径抑制剂和免疫治疗剂组合的组合物
|
|
MX2019012076A
(es)
|
2017-05-30 |
2019-12-09 |
Bristol Myers Squibb Co |
Composiciones que comprenden un anticuerpo anti gen-3 de activacion del linfocito (lag-3) o un anticuerpo anti-lag-3 y un anticuerpo anti muerte celular programada 1 (pd-1) o anti ligando 1 de muerte celular programada (pd-l1).
|
|
US20210246227A1
(en)
|
2017-05-31 |
2021-08-12 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
|
WO2018222685A1
(en)
|
2017-05-31 |
2018-12-06 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that immunospecifically bind to btn1a1
|
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
|
CN111344303A
(zh)
|
2017-06-01 |
2020-06-26 |
Xencor股份有限公司 |
结合cd123和cd3的双特异性抗体
|
|
EP3630126A4
(en)
*
|
2017-06-02 |
2021-03-17 |
The Penn State Research Foundation |
CERAMIDE NANOLIPOSOMES, COMPOSITIONS AND METHODS OF USE FOR IMMUNOTHERAPY
|
|
JP2020522489A
(ja)
|
2017-06-02 |
2020-07-30 |
ジュノー セラピューティクス インコーポレイテッド |
養子細胞療法を用いる処置のための製造物品および方法
|
|
WO2018226671A1
(en)
|
2017-06-06 |
2018-12-13 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that bind to btn1a1 or btn1a1-ligands
|
|
BR112019026564A2
(pt)
|
2017-06-14 |
2020-06-30 |
Adc Therapeutics Sa |
regimes de dosagem para a administração de um adc anti-cd19
|
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
EP3641812A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
|
MX2019015155A
(es)
|
2017-06-29 |
2020-08-03 |
Juno Therapeutics Inc |
Modelo de raton para valorar toxicidades asociadas con inmunoterapias.
|
|
WO2019023525A1
(en)
*
|
2017-07-28 |
2019-01-31 |
Dana-Farber Cancer Institute, Inc. |
ENHANCED IMMUNOTHERAPY OF CANCER USING TARGETED TRANSCRIPTION MODULATORS
|
|
US11899017B2
(en)
|
2017-07-28 |
2024-02-13 |
Bristol-Myers Squibb Company |
Predictive peripheral blood biomarker for checkpoint inhibitors
|
|
WO2019036438A1
(en)
*
|
2017-08-14 |
2019-02-21 |
Phosphorex, Inc. |
ADENOSINE RECEPTOR ANTAGONIST MICROPARTICLE FORMULATIONS FOR THE TREATMENT OF CANCER
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
IL272697B2
(en)
|
2017-08-18 |
2023-12-01 |
Adastra Pharmaceuticals Inc |
A polymorphic form of TG02
|
|
EA202090634A1
(ru)
|
2017-08-28 |
2020-06-17 |
Бристол-Маерс Сквибб Компани |
Антагонисты tim-3 для лечения и диагностики онкологических заболеваний
|
|
KR20200052327A
(ko)
|
2017-09-04 |
2020-05-14 |
아게누스 인코포레이티드 |
혼합 계통 백혈병 (mll)-특이적 포스포펩타이드에 결합하는 t 세포 수용체 및 그것의 사용 방법
|
|
CN118909118A
(zh)
|
2017-09-07 |
2024-11-08 |
奥古斯塔大学研究所公司 |
程序性细胞死亡蛋白1抗体
|
|
PE20201183A1
(es)
|
2017-10-13 |
2020-11-03 |
Harpoon Therapeutics Inc |
Proteinas trispecificas y metodos de uso
|
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
|
CN109662966A
(zh)
*
|
2017-10-16 |
2019-04-23 |
北京莱科金基因科技有限责任公司 |
伊曲茶碱在制备用于肿瘤治疗的药物中的用途
|
|
EP3697434A1
(en)
|
2017-10-18 |
2020-08-26 |
Vivia Biotech, S.L. |
Bite-activated car-t cells
|
|
SG11202003501XA
(en)
|
2017-11-01 |
2020-05-28 |
Juno Therapeutics Inc |
Antibodies and chimeric antigen receptors specific for b-cell maturation antigen
|
|
MX2020004572A
(es)
|
2017-11-01 |
2020-10-07 |
Juno Therapeutics Inc |
Receptores de antigenos quimericos especificos para el antigeno de maduracion de celulas b y polinucleotidos que codifican los mismos.
|
|
WO2019089858A2
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
EP3710053A1
(en)
|
2017-11-16 |
2020-09-23 |
Novartis AG |
Combination therapies
|
|
AU2018367524B2
(en)
|
2017-11-17 |
2022-09-15 |
Merck Sharp & Dohme Llc |
Antibodies specific for immunoglobulin-like transcript 3 (ILT3) and uses thereof
|
|
WO2019097479A1
(en)
|
2017-11-17 |
2019-05-23 |
Novartis Ag |
Novel dihydroisoxazole compounds and their use for the treatment of hepatitis b
|
|
CA3083949A1
(en)
|
2017-11-30 |
2020-06-06 |
Novartis Ag |
Bcma-targeting chimeric antigen receptor, and uses thereof
|
|
JP7348899B2
(ja)
|
2017-12-08 |
2023-09-21 |
マレンゴ・セラピューティクス,インコーポレーテッド |
多重特異性分子及びその使用
|
|
US11946094B2
(en)
|
2017-12-10 |
2024-04-02 |
Augusta University Research Institute, Inc. |
Combination therapies and methods of use thereof
|
|
KR20200110745A
(ko)
|
2017-12-15 |
2020-09-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
항 - cct5 결합 분자 및 이의 사용 방법
|
|
CN111433210A
(zh)
|
2017-12-20 |
2020-07-17 |
诺华股份有限公司 |
作为抗病毒药的稠合三环吡唑并-二氢吡嗪基-吡啶酮化合物
|
|
US11324774B2
(en)
|
2018-01-05 |
2022-05-10 |
Augusta University Research Institute, Inc. |
Compositions of oral alkaline salts and metabolic acid inducers and uses thereof
|
|
US12247060B2
(en)
|
2018-01-09 |
2025-03-11 |
Marengo Therapeutics, Inc. |
Calreticulin binding constructs and engineered T cells for the treatment of diseases
|
|
JP2021510733A
(ja)
|
2018-01-12 |
2021-04-30 |
ケーディーエーシー セラピューティクス,インコーポレーテッドKdac Therapeutics, Inc. |
がんの処置のための選択的ヒストンデアセチラーゼ3(hdac3)インヒビターと免疫治療剤との組み合わせ
|
|
JP2021510697A
(ja)
|
2018-01-12 |
2021-04-30 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
がん処置のための坑il−8抗体及び坑pd−1抗体を用いる組合せ治療
|
|
CA3096287A1
(en)
|
2018-01-22 |
2019-07-25 |
Pascal Biosciences Inc. |
Cannabinoids and derivatives for promoting immunogenicity of tumor and infected cells
|
|
CN112566934B
(zh)
|
2018-01-23 |
2024-09-17 |
奈斯科尔公司 |
B7-h4抗体及其使用方法
|
|
WO2019148089A1
(en)
|
2018-01-26 |
2019-08-01 |
Orionis Biosciences Inc. |
Xcr1 binding agents and uses thereof
|
|
WO2019149716A1
(en)
|
2018-01-31 |
2019-08-08 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies comprising an antigen-binding site binding to lag3
|
|
KR20200128014A
(ko)
|
2018-01-31 |
2020-11-11 |
셀진 코포레이션 |
입양 세포 요법 및 체크포인트 억제제를 이용한 병용 요법
|
|
WO2019157124A1
(en)
|
2018-02-08 |
2019-08-15 |
Bristol-Myers Squibb Company |
Combination of a tetanus toxoid, anti-ox40 antibody and/or anti-pd-1 antibody to treat tumors
|
|
CN111801331A
(zh)
|
2018-02-28 |
2020-10-20 |
诺华股份有限公司 |
吲哚-2-羰基化合物及其用于治疗乙型肝炎的用途
|
|
US20210002373A1
(en)
|
2018-03-01 |
2021-01-07 |
Nextcure, Inc. |
KLRG1 Binding Compositions and Methods of Use Thereof
|
|
IL277095B2
(en)
|
2018-03-07 |
2025-10-01 |
Pfizer |
Preparations containing anti-PD-1 antibody
|
|
EP3765085A1
(en)
|
2018-03-12 |
2021-01-20 |
Université de Paris |
Use of caloric restriction mimetics for potentiating chemo-immunotherapy for the treatment of cancers
|
|
US20210009711A1
(en)
|
2018-03-14 |
2021-01-14 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
|
BR122022000386B1
(pt)
|
2018-03-14 |
2022-09-27 |
Surface Oncology, Inc |
Anticorpos que se ligam a cd39, composição farmacêutica e kit dos mesmos
|
|
WO2019178362A1
(en)
|
2018-03-14 |
2019-09-19 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
US20210361734A1
(en)
*
|
2018-03-19 |
2021-11-25 |
9 Meters Biopharma, Inc. |
Compositions and methods for potentiating immune checkpoint inhibitor therapy
|
|
WO2019195658A1
(en)
|
2018-04-05 |
2019-10-10 |
Dana-Farber Cancer Institute, Inc. |
Sting levels as a biomarker for cancer immunotherapy
|
|
KR20200142542A
(ko)
|
2018-04-12 |
2020-12-22 |
브리스톨-마이어스 스큅 컴퍼니 |
Cd73 길항제 항체 및 pd-1/pd-l1 축 길항제 항체에 의한 항암 조합 요법
|
|
EP3782618A4
(en)
|
2018-04-16 |
2022-01-26 |
OnQuality Pharmaceuticals China Ltd. |
METHODS OF PREVENTING OR TREATMENT OF SIDE EFFECTS OF CANCER THERAPY
|
|
SG11202010011RA
(en)
|
2018-04-17 |
2020-11-27 |
Celldex Therapeutics Inc |
Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs
|
|
WO2019204665A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
JP7516254B2
(ja)
|
2018-04-18 |
2024-07-16 |
ゼンコア インコーポレイテッド |
Il-15/il-15raヘテロ二量体fc融合タンパク質およびその使用
|
|
US11065317B2
(en)
|
2018-04-26 |
2021-07-20 |
Agenus Inc. |
Heat shock protein-binding peptide compositions and methods of use thereof
|
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
|
US20210396739A1
(en)
|
2018-05-01 |
2021-12-23 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
KR20210016562A
(ko)
|
2018-05-23 |
2021-02-16 |
에이디씨 테라퓨틱스 에스에이 |
분자 애쥬번트
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
US11932681B2
(en)
|
2018-05-31 |
2024-03-19 |
Novartis Ag |
Hepatitis B antibodies
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
UY38251A
(es)
|
2018-06-01 |
2019-12-31 |
Novartis Ag |
Moléculas de unión contra bcma y usos de las mismas
|
|
EP3801617A1
(en)
|
2018-06-01 |
2021-04-14 |
Novartis Ag |
Dosing of a bispecific antibody that bind cd123 and cd3
|
|
US20210221908A1
(en)
|
2018-06-03 |
2021-07-22 |
Lamkap Bio Beta Ltd. |
Bispecific antibodies against ceacam5 and cd47
|
|
US11505782B2
(en)
|
2018-06-04 |
2022-11-22 |
Calidi Biotherapeutics, Inc. |
Cell-based vehicles for potentiation of viral therapy
|
|
JP7438988B2
(ja)
|
2018-06-13 |
2024-02-27 |
ノバルティス アーゲー |
Bcmaキメラ抗原受容体及びその使用
|
|
IL319456A
(en)
|
2018-06-20 |
2025-05-01 |
Incyte Holdings Corp |
ANTI-PD-1 ANTIBODIES AND THEIR USES
|
|
TW202504917A
(zh)
|
2018-06-21 |
2025-02-01 |
美商再生元醫藥公司 |
用雙特異性抗CD3xMUC16抗體及抗PD-1抗體治療癌症之方法
|
|
JP7554742B2
(ja)
|
2018-07-03 |
2024-09-20 |
マレンゴ・セラピューティクス,インコーポレーテッド |
抗tcr抗体分子およびその使用
|
|
ES2963694T3
(es)
|
2018-07-10 |
2024-04-01 |
Novartis Ag |
Derivados de 3-(5-hidroxi-1-oxoisoindolin-2-il)piperidin-2,6-diona y su uso en el tratamiento de enfermedades dependientes de la proteína con dedos de cinc 2 de la familia ikaros (ikzf2)
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
WO2020014583A1
(en)
|
2018-07-13 |
2020-01-16 |
Bristol-Myers Squibb Company |
Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a mehtod of treating a cancer or a solid tumor
|
|
WO2020021061A1
(en)
|
2018-07-26 |
2020-01-30 |
Pieris Pharmaceuticals Gmbh |
Humanized anti-pd-1 antibodies and uses thereof
|
|
JP2021532143A
(ja)
|
2018-07-26 |
2021-11-25 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
癌の処置のためのlag−3併用療法
|
|
WO2020037215A1
(en)
|
2018-08-17 |
2020-02-20 |
Icahn School Of Medicine At Mount Sinai |
Recombinant newcastle disease viruses and uses thereof for the prevention of rsv disease or human metapneumovirus disease
|
|
CA3106881A1
(en)
|
2018-08-27 |
2020-03-05 |
Pieris Pharmaceuticals Gmbh |
Combination therapies comprising cd137/her2 bispecific agents and pd-1 axis inhibitors and uses thereof
|
|
CN109053895B
(zh)
*
|
2018-08-30 |
2020-06-09 |
中山康方生物医药有限公司 |
抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
|
|
US20210340279A1
(en)
|
2018-08-31 |
2021-11-04 |
Yale University |
Compositions and methods of using cell-penetrating antibodies in combination with immune checkpoint modulators
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
US11359024B2
(en)
|
2018-09-07 |
2022-06-14 |
Pfizer Inc. |
Anti-AVB8 antibodies and compositions and uses thereof
|
|
WO2020053742A2
(en)
|
2018-09-10 |
2020-03-19 |
Novartis Ag |
Anti-hla-hbv peptide antibodies
|
|
EP3849554B1
(en)
|
2018-09-11 |
2025-01-29 |
Curis, Inc. |
Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety
|
|
CN121426803A
(zh)
|
2018-09-12 |
2026-01-30 |
诺华股份有限公司 |
抗病毒吡啶并吡嗪二酮化合物
|
|
CA3112578A1
(en)
|
2018-09-19 |
2020-03-26 |
Alpine Immune Sciences, Inc. |
Methods and uses of variant cd80 fusion proteins and related constructs
|
|
JP7618950B2
(ja)
|
2018-09-19 |
2025-01-22 |
インサーム (インスティテュート ナショナル デ ラ サンテ エ デ ラ ルシェルシェ メディカル) |
免疫チェックポイント治療に抵抗性のある癌の治療のための方法および医薬組成物
|
|
WO2020061129A1
(en)
|
2018-09-19 |
2020-03-26 |
President And Fellows Of Harvard College |
Compositions and methods for labeling and modulation of cells in vitro and in vivo
|
|
WO2020061482A1
(en)
|
2018-09-21 |
2020-03-26 |
Harpoon Therapeutics, Inc. |
Egfr binding proteins and methods of use
|
|
MX2021003554A
(es)
|
2018-09-25 |
2021-05-27 |
Harpoon Therapeutics Inc |
Proteinas de union a dll3 y metodos de uso.
|
|
WO2020069372A1
(en)
|
2018-09-27 |
2020-04-02 |
Elstar Therapeutics, Inc. |
Csf1r/ccr2 multispecific antibodies
|
|
EP3856779A1
(en)
|
2018-09-28 |
2021-08-04 |
Novartis AG |
Cd22 chimeric antigen receptor (car) therapies
|
|
US20210347851A1
(en)
|
2018-09-28 |
2021-11-11 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
|
WO2020065453A1
(en)
|
2018-09-29 |
2020-04-02 |
Novartis Ag |
Process of manufacture of a compound for inhibiting the activity of shp2
|
|
WO2020070053A1
(en)
|
2018-10-01 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
JP7612571B2
(ja)
|
2018-10-03 |
2025-01-14 |
ゼンコア インコーポレイテッド |
Il-12ヘテロ二量体fc-融合タンパク質
|
|
EP3864047A2
(en)
|
2018-10-12 |
2021-08-18 |
Xencor, Inc. |
Pd-1 targeted il-15/il-15ralpha fc fusion proteins and uses in combination therapies thereof
|
|
IL282317B2
(en)
|
2018-10-17 |
2024-04-01 |
Biolinerx Ltd |
Treatment of metastatic pancreatic adenocarcinoma
|
|
EP3873532A1
(en)
|
2018-10-31 |
2021-09-08 |
Novartis AG |
Dc-sign antibody drug conjugates
|
|
WO2020092839A1
(en)
|
2018-10-31 |
2020-05-07 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
|
US12257286B2
(en)
|
2018-10-31 |
2025-03-25 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
|
MA54079A
(fr)
|
2018-11-01 |
2021-09-08 |
Juno Therapeutics Inc |
Récepteurs antigéniques chimériques spécifiques du gprc5d (élément d du groupe 5 de classe c des récepteurs couplés à la protéine g)
|
|
AU2019372331A1
(en)
|
2018-11-01 |
2021-05-27 |
Juno Therapeutics, Inc. |
Methods for treatment using chimeric antigen receptors specific for B-cell maturation antigen
|
|
CA3118892A1
(en)
|
2018-11-08 |
2020-05-14 |
Orionis Biosciences, Inc. |
Modulation of dendritic cell lineages
|
|
US20220001026A1
(en)
|
2018-11-08 |
2022-01-06 |
Modernatx, Inc. |
Use of mrna encoding ox40l to treat cancer in human patients
|
|
PL3880186T3
(pl)
|
2018-11-14 |
2024-07-22 |
Regeneron Pharmaceuticals, Inc. |
Doogniskowe podawanie inhibitorów pd-1 do leczenia raka skóry
|
|
CN112996814B
(zh)
|
2018-11-14 |
2025-01-03 |
拜耳公司 |
用于治疗癌症的抗ceacam6和抗pd-1或抗pd-l1抗体的药物组合
|
|
KR20210104713A
(ko)
|
2018-11-16 |
2021-08-25 |
주노 쎄러퓨티크스 인코퍼레이티드 |
B 세포 악성 종양 치료를 위한 조작된 t 세포 투약 방법
|
|
WO2020102728A1
(en)
|
2018-11-16 |
2020-05-22 |
Neoimmunetech, Inc. |
Method of treating a tumor with a combination of il-7 protein and an immune checkpoint inhibitor
|
|
EP3886842A1
(en)
|
2018-11-26 |
2021-10-06 |
Debiopharm International SA |
Combination treatment of hiv infections
|
|
ES2971964T3
(es)
|
2018-11-28 |
2024-06-10 |
Inst Nat Sante Rech Med |
Métodos y kit para someter a ensayo el potencial lítico de células efectoras inmunitarias
|
|
FI3886875T3
(fi)
|
2018-11-30 |
2024-07-23 |
Juno Therapeutics Inc |
Adoptiivista soluterapiaa käyttäviä hoitomenetelmiä
|
|
SG11202105689XA
(en)
|
2018-12-03 |
2021-06-29 |
Agensys Inc |
Pharmaceutical compositions comprising anti-191p4d12 antibody drug conjugates and methods of use thereof
|
|
US20220018835A1
(en)
|
2018-12-07 |
2022-01-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
US20220047556A1
(en)
|
2018-12-17 |
2022-02-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sulconazole as a furin inhibitor
|
|
CN113164778B
(zh)
|
2018-12-19 |
2024-07-26 |
拜耳公司 |
抗ceacam6和tim3抗体的药物组合
|
|
AU2019402189B2
(en)
|
2018-12-20 |
2023-04-13 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
CN113438961A
(zh)
|
2018-12-20 |
2021-09-24 |
Xencor股份有限公司 |
含有IL-15/IL-15Rα和NKG2D抗原结合结构域的靶向异二聚体Fc融合蛋白
|
|
IL282838B2
(en)
|
2018-12-21 |
2025-05-01 |
Valerio Therapeutics |
Conjugated nucleic acid molecules and their uses
|
|
CN113195541B
(zh)
|
2018-12-21 |
2024-08-30 |
诺华股份有限公司 |
针对pmel17的抗体及其缀合物
|
|
AU2020208909B2
(en)
|
2019-01-15 |
2025-02-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Mutated interleukin-34 (IL-34) polypeptides and uses thereof in therapy
|
|
JP7636330B2
(ja)
|
2019-01-17 |
2025-02-26 |
ジョージア テック リサーチ コーポレイション |
酸化コレステロールを含有する薬物送達システム
|
|
AU2020208637A1
(en)
|
2019-01-18 |
2021-09-09 |
Dracen Pharmaceuticals, Inc. |
Combinaton therapy with a don prodrug and an immune checkpoint inhibitor
|
|
TWI850316B
(zh)
|
2019-01-21 |
2024-08-01 |
法商賽諾菲公司 |
用於晚期實性瘤癌症之治療性rna及抗pd1抗體
|
|
AU2020215576A1
(en)
|
2019-01-29 |
2021-07-08 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ROR1)
|
|
JP7488826B2
(ja)
|
2019-02-15 |
2024-05-22 |
ノバルティス アーゲー |
置換3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用
|
|
AU2020222345B2
(en)
|
2019-02-15 |
2022-11-17 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US20220107320A1
(en)
|
2019-02-15 |
2022-04-07 |
Incelldx, Inc. |
Assaying Bladder-Associated Samples, Identifying and Treating Bladder-Associated Neoplasia, and Kits for Use Therein
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
AU2020226893B2
(en)
|
2019-02-21 |
2025-02-27 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to T cell related cancer cells and uses thereof
|
|
GB2597851B
(en)
|
2019-02-21 |
2024-05-29 |
Marengo Therapeutics Inc |
Antibody molecules that bind to NKP30 and uses thereof
|
|
WO2020172553A1
(en)
|
2019-02-22 |
2020-08-27 |
Novartis Ag |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
MX2021010228A
(es)
|
2019-02-28 |
2021-10-26 |
Regeneron Pharma |
Administracion de inhibidores de pd-1 para el tratamiento de cancer de piel.
|
|
WO2020180727A1
(en)
|
2019-03-06 |
2020-09-10 |
Regeneron Pharmaceuticals, Inc. |
Il-4/il-13 pathway inhibitors for enhanced efficacy in treating cancer
|
|
US20230083015A1
(en)
|
2019-03-26 |
2023-03-16 |
The Regents Of The University Of Michigan |
Small molecule degraders of stat3
|
|
WO2020205467A1
(en)
|
2019-03-29 |
2020-10-08 |
The Regents Of The University Of Michigan |
Stat3 protein degraders
|
|
BR112021019819A2
(pt)
*
|
2019-04-02 |
2021-12-07 |
Univ Texas |
Combinações de inibidores de transcrição e inibidores dos pontos de controle imunológicos para o tratamento da doença
|
|
WO2020201362A2
(en)
|
2019-04-02 |
2020-10-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of predicting and preventing cancer in patients having premalignant lesions
|
|
WO2020208060A1
(en)
|
2019-04-09 |
2020-10-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
|
US20220220480A1
(en)
|
2019-04-17 |
2022-07-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
|
EP3725370A1
(en)
|
2019-04-19 |
2020-10-21 |
ImmunoBrain Checkpoint, Inc. |
Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease
|
|
WO2020232019A1
(en)
|
2019-05-13 |
2020-11-19 |
Regeneron Pharmaceuticals, Inc. |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating cancer
|
|
AU2020278465A1
(en)
|
2019-05-20 |
2021-12-09 |
Dana-Farber Cancer Institute, Inc. |
Boronic ester prodrugs and uses thereof
|
|
EP3976090A1
(en)
|
2019-05-24 |
2022-04-06 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
|
WO2020252336A1
(en)
|
2019-06-12 |
2020-12-17 |
Vanderbilt University |
Dibenzylamines as amino acid transport inhibitors
|
|
US20220304984A1
(en)
|
2019-06-12 |
2022-09-29 |
Vanderbilt University |
Amino acid transport inhibitors and the uses thereof
|
|
CN114206379A
(zh)
|
2019-06-18 |
2022-03-18 |
爱尔兰詹森科学公司 |
乙型肝炎病毒(hbv)疫苗和抗pd-1抗体的组合
|
|
EP3986454A1
(en)
|
2019-06-18 |
2022-04-27 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and anti-pd-1 or anti-pd-l1 antibody
|
|
AU2020302928A1
(en)
|
2019-06-27 |
2022-02-03 |
Medstar Health, Inc. |
HDAC6-activated macrophages, compositions, and uses thereof
|
|
JP7738909B2
(ja)
|
2019-07-16 |
2025-09-16 |
ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン |
Eed阻害剤としてのイミダゾピリミジンおよびその使用
|
|
PH12022550243A1
(en)
*
|
2019-08-02 |
2023-04-24 |
Akeso Pharmaceuticals Inc |
Anti-ctla4-anti-pd-1 bispecific antibody and uses thereof
|
|
JP2022542437A
(ja)
|
2019-08-02 |
2022-10-03 |
ランティオペプ ベスローテン ヴェンノーツハップ |
癌の処置に用いるアンジオテンシン2型(at2)受容体アゴニスト
|
|
CN119409834A
(zh)
|
2019-08-12 |
2025-02-11 |
北京恩瑞尼生物科技股份有限公司 |
用于通过cd39表达细胞的adcc靶向促进和增强t细胞介导的免疫反应的方法和组合物
|
|
GB201912107D0
(en)
|
2019-08-22 |
2019-10-09 |
Amazentis Sa |
Combination
|
|
WO2021041532A1
(en)
|
2019-08-26 |
2021-03-04 |
Dana-Farber Cancer Institute, Inc. |
Use of heparin to promote type 1 interferon signaling
|
|
CA3151824A1
(en)
|
2019-08-27 |
2021-03-04 |
The Regents Of The University Of Michigan |
Cereblon e3 ligase inhibitors
|
|
CR20220076A
(es)
|
2019-08-30 |
2022-06-24 |
Agenus Inc |
Anticuerpos anti-cd96 y sus métodos de uso
|
|
EP4031178A1
(en)
|
2019-09-16 |
2022-07-27 |
Surface Oncology, Inc. |
Anti-cd39 antibody compositions and methods
|
|
JP2022548665A
(ja)
|
2019-09-18 |
2022-11-21 |
ノバルティス アーゲー |
Nkg2d融合タンパク質及びその使用
|
|
WO2021053559A1
(en)
|
2019-09-18 |
2021-03-25 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
US12441807B2
(en)
|
2019-09-18 |
2025-10-14 |
Lamkap Bio Alpha AG |
Bispecific antibodies against CEACAM5 and CD3
|
|
TW202124446A
(zh)
|
2019-09-18 |
2021-07-01 |
瑞士商諾華公司 |
與entpd2抗體之組合療法
|
|
EP4031241A1
(en)
|
2019-09-19 |
2022-07-27 |
The Regents Of The University Of Michigan |
Spirocyclic androgen receptor protein degraders
|
|
WO2021061837A1
(en)
|
2019-09-23 |
2021-04-01 |
President And Fellows Of Harvard College |
Biomaterial-based antigen free vaccine and the use thereof
|
|
MX2022003357A
(es)
|
2019-09-25 |
2022-05-03 |
Seagen Inc |
Combinación de anticuerpo anti-cd30 conjugado con un farmaco, anti-pd-1 y quimioterapia para el tratamiento de cánceres hematopoyéticos.
|
|
CN115087671A
(zh)
|
2019-09-25 |
2022-09-20 |
表面肿瘤学公司 |
抗il-27抗体及其用途
|
|
US11667613B2
(en)
|
2019-09-26 |
2023-06-06 |
Novartis Ag |
Antiviral pyrazolopyridinone compounds
|
|
CA3151322A1
(en)
|
2019-10-01 |
2021-04-08 |
Silverback Therapeutics, Inc. |
Combination therapy with immune stimulatory conjugates
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
WO2021067863A2
(en)
|
2019-10-03 |
2021-04-08 |
Xencor, Inc. |
Targeted il-12 heterodimeric fc-fusion proteins
|
|
WO2021064184A1
(en)
|
2019-10-04 |
2021-04-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
WO2021097256A1
(en)
|
2019-11-14 |
2021-05-20 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
|
BR112022009521A2
(pt)
*
|
2019-11-20 |
2022-08-16 |
Gi Cell Inc |
Composição de meio para cultura de células t e método para cultura de células t usando a mesma
|
|
JP7805928B2
(ja)
|
2019-11-26 |
2026-01-26 |
ノバルティス アーゲー |
Cd19及びcd22キメラ抗原受容体及びその使用
|
|
WO2021108025A1
(en)
|
2019-11-26 |
2021-06-03 |
Massachusetts Institute Of Technology |
Cell-based cancer vaccines and cancer therapies
|
|
GB201917254D0
(en)
|
2019-11-27 |
2020-01-08 |
Adc Therapeutics Sa |
Combination therapy
|
|
EP3831849A1
(en)
|
2019-12-02 |
2021-06-09 |
LamKap Bio beta AG |
Bispecific antibodies against ceacam5 and cd47
|
|
WO2021113777A2
(en)
|
2019-12-04 |
2021-06-10 |
Orna Therapeutics, Inc. |
Circular rna compositions and methods
|
|
US11897950B2
(en)
|
2019-12-06 |
2024-02-13 |
Augusta University Research Institute, Inc. |
Osteopontin monoclonal antibodies
|
|
AU2020399976A1
(en)
|
2019-12-09 |
2022-06-30 |
Merck Sharp & Dohme B.V. |
Combination therapy with LIV1-ADC and PD-1 antagonist
|
|
CN115052662A
(zh)
|
2019-12-20 |
2022-09-13 |
诺华股份有限公司 |
抗TGFβ抗体和检查点抑制剂用于治疗增殖性疾病的用途
|
|
GB2609554B
(en)
|
2020-01-03 |
2025-08-20 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
|
CN111110655B
(zh)
*
|
2020-01-20 |
2020-12-25 |
山东大学 |
一种纳米复合物及其制备方法和应用
|
|
TW202136318A
(zh)
|
2020-01-28 |
2021-10-01 |
美商建南德克公司 |
用於治療癌症的 IL15/IL15R α 異二聚體 Fc 融合蛋白質
|
|
US20230086099A1
(en)
|
2020-01-30 |
2023-03-23 |
Ona Therapeutics, S.L. |
Combination therapy for treatment of cancer and cancer metastasis
|
|
WO2021171264A1
(en)
|
2020-02-28 |
2021-09-02 |
Novartis Ag |
Dosing of a bispecific antibody that binds cd123 and cd3
|
|
MX2022011050A
(es)
|
2020-03-06 |
2022-12-15 |
Ona Therapeutics S L |
Anticuerpos anti-cd36 y su uso para tratar cancer.
|
|
MX2022011677A
(es)
|
2020-03-20 |
2023-01-11 |
Orna Therapeutics Inc |
Composiciones y métodos de arn circular.
|
|
US12522623B2
(en)
|
2020-03-26 |
2026-01-13 |
Regents Of The University Of Michigan |
Small molecule STAT protein degraders
|
|
AU2021251265A1
(en)
|
2020-04-10 |
2022-11-03 |
Juno Therapeutics, Inc. |
Methods and uses related to cell therapy engineered with a chimeric antigen receptor targeting B-cell maturation antigen
|
|
US20230181756A1
(en)
|
2020-04-30 |
2023-06-15 |
Novartis Ag |
Ccr7 antibody drug conjugates for treating cancer
|
|
MY209480A
(en)
|
2020-05-01 |
2025-07-11 |
Ngm Biopharmaceuticals Inc |
Ilt-binding agents and methods of use thereof
|
|
JP7776145B2
(ja)
|
2020-05-13 |
2025-11-26 |
マサチューセッツ インスティテュート オブ テクノロジー |
ポリマーマイクロデバイスの組成物およびがん免疫療法におけるその使用
|
|
TWI899236B
(zh)
|
2020-05-26 |
2025-10-01 |
美商再生元醫藥公司 |
通過投予pd-1抑制劑治療子宮頸癌的方法
|
|
US20230212231A1
(en)
|
2020-05-26 |
2023-07-06 |
Institut National De La Santé Et De La Recherche Médicale (Inserm) |
Severe acute respiratory syndrome coronavirus 2 (sars-cov-2) polypeptides and uses thereof for vaccine purposes
|
|
WO2021243207A1
(en)
|
2020-05-28 |
2021-12-02 |
Modernatx, Inc. |
Use of mrnas encoding ox40l, il-23 and il-36gamma for treating cancer
|
|
US11767353B2
(en)
|
2020-06-05 |
2023-09-26 |
Theraly Fibrosis, Inc. |
Trail compositions with reduced immunogenicity
|
|
CA3185455A1
(en)
|
2020-06-11 |
2021-12-16 |
Novartis Ag |
Zbtb32 inhibitors and uses thereof
|
|
TW202214857A
(zh)
|
2020-06-19 |
2022-04-16 |
法商昂席歐公司 |
新型結合核酸分子及其用途
|
|
MX2022015852A
(es)
|
2020-06-23 |
2023-01-24 |
Novartis Ag |
Regimen de dosificacion que comprende derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona.
|
|
WO2021260675A1
(en)
|
2020-06-24 |
2021-12-30 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
|
WO2022011204A1
(en)
|
2020-07-10 |
2022-01-13 |
The Regents Of The University Of Michigan |
Small molecule androgen receptor protein degraders
|
|
US20230233690A1
(en)
|
2020-07-10 |
2023-07-27 |
The Regents Of The University Of Michigan |
Androgen receptor protein degraders
|
|
JP7819176B2
(ja)
|
2020-08-03 |
2026-02-24 |
ノバルティス アーゲー |
ヘテロアリール置換3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用
|
|
GB2616354A
(en)
|
2020-08-26 |
2023-09-06 |
Marengo Therapeutics Inc |
Methods of detecting TRBC1 or TRBC2
|
|
MA71214A
(fr)
|
2020-08-26 |
2025-04-30 |
Regeneron Pharmaceuticals, Inc. |
Méthodes de traitement du cancer par administration d'un inhibiteur de pd-1
|
|
WO2022049526A1
(en)
|
2020-09-02 |
2022-03-10 |
Pharmabcine Inc. |
Combination therapy of a pd-1 antagonist and an antagonist for vegfr-2 for treating patients with cancer
|
|
KR20230061499A
(ko)
|
2020-09-03 |
2023-05-08 |
리제너론 파마슈티칼스 인코포레이티드 |
Pd-1 저해제 투여에 의한 암 통증 치료 방법
|
|
KR20230060527A
(ko)
*
|
2020-09-08 |
2023-05-04 |
주식회사 유틸렉스 |
Pd-1 폴리펩티드 변이체
|
|
MX2023003414A
(es)
|
2020-09-24 |
2023-04-14 |
Merck Sharp & Dohme Llc |
Formulaciones estables de anticuerpos programados del receptor de muerte 1 (pd-1) y variantes de hialuronidasa y fragmentos de las mismas y metodos de uso de las mismas.
|
|
EP4221842A4
(en)
|
2020-10-02 |
2024-11-20 |
Dracen Pharmaceuticals, Inc. |
LYOPHILIZED COMPOSITION CONTAINING (S)-ISOPROPYL 2-((S)-2-ACETAMIDO-3-(1H-INDOL-3-YL)PROPANAMIDO)-6-DIAZO-5-OXOHEXANOATE FOR SUBCUTANEOUS ADMINISTRATION AND ITS USE
|
|
EP4222171A1
(en)
|
2020-10-02 |
2023-08-09 |
Regeneron Pharmaceuticals, Inc. |
Combination of antibodies for treating cancer with reduced cytokine release syndrome
|
|
IL301907A
(en)
|
2020-10-23 |
2023-06-01 |
Bristol Myers Squibb Co |
LAG-3 antagonist therapy for lung cancer
|
|
JP2023548529A
(ja)
|
2020-11-06 |
2023-11-17 |
ノバルティス アーゲー |
Cd19結合分子及びその使用
|
|
MX2023005570A
(es)
|
2020-11-12 |
2023-05-29 |
Inst Nat Sante Rech Med |
Anticuerpos conjugados o fusionados al dominio de union del receptor de la proteina de la espicula de sars-cov-2 y usos de los mismos con fines de vacunacion.
|
|
WO2022101463A1
(en)
|
2020-11-16 |
2022-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of the last c-terminal residues m31/41 of zikv m ectodomain for triggering apoptotic cell death
|
|
US20220168293A1
(en)
|
2020-12-02 |
2022-06-02 |
Pfizer Inc. |
Time to resolution of axitinib-related adverse events
|
|
WO2022125497A1
(en)
|
2020-12-08 |
2022-06-16 |
Infinity Pharmaceuticals, Inc. |
Eganelisib for use in the treatment of pd-l1 negative cancer
|
|
KR20220082558A
(ko)
|
2020-12-10 |
2022-06-17 |
재단법인 의약바이오컨버젼스연구단 |
면역 증진 활성이 있는 신규 crs 단편 펩타이드 및 이의 용도
|
|
PL4055055T3
(pl)
|
2020-12-18 |
2024-04-15 |
Lamkap Bio Beta Ag |
Przeciwciała dwuswoiste przeciwko ceacam5 i cd47
|
|
WO2022162569A1
(en)
|
2021-01-29 |
2022-08-04 |
Novartis Ag |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
US20240423972A1
(en)
|
2021-02-01 |
2024-12-26 |
Yale University |
Chemotherapeutic bioadhesive particles with immunostimulatory molecules for cancer treatment
|
|
EP4292596A4
(en)
|
2021-02-10 |
2025-03-19 |
Curon Biopharmaceutical (Shanghai) Co., Limited |
METHODS AND COMBINATIONS FOR THE TREATMENT OF TUMORS
|
|
GB202102396D0
(en)
|
2021-02-19 |
2021-04-07 |
Adc Therapeutics Sa |
Molecular adjuvant
|
|
US20240166647A1
(en)
|
2021-03-03 |
2024-05-23 |
The Regents Of The University Of Michigan |
Cereblon Ligands
|
|
US20240190874A1
(en)
|
2021-03-03 |
2024-06-13 |
The Regents Of The University Of Michigan |
Small molecule degraders of androgen receptor
|
|
US20240092942A1
(en)
|
2021-03-05 |
2024-03-21 |
Leadartis, S.L. |
Trimeric polypeptides and uses thereof in the treatment of cancer
|
|
WO2022204672A1
(en)
|
2021-03-23 |
2022-09-29 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer in immunosuppressed or immunocompromised patients by administering a pd-1 inhibitor
|
|
BR112023019847A2
(pt)
|
2021-03-29 |
2023-11-07 |
Juno Therapeutics Inc |
Métodos para dosagem e tratamento com uma combinação de uma terapia com inibidor de ponto de verificação e uma terapia com célula t car
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
AU2022255506A1
(en)
|
2021-04-08 |
2023-11-09 |
Marengo Therapeutics, Inc. |
Multifunctional molecules binding to tcr and uses thereof
|
|
US20240228659A1
(en)
|
2021-04-14 |
2024-07-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve nk cells cytotoxicity
|
|
JP2024517409A
(ja)
|
2021-04-16 |
2024-04-22 |
ノバルティス アーゲー |
抗体薬物結合体及びその作成方法
|
|
JP2024515220A
(ja)
|
2021-04-26 |
2024-04-05 |
セラニーズ・イーブイエイ・パフォーマンス・ポリマーズ・エルエルシー |
高分子薬剤化合物の持続放出用の埋め込み型デバイス
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
AU2022277263A1
(en)
|
2021-05-21 |
2023-12-14 |
Tianjin Lipogen Technology Co., Ltd |
Pharmaceutical combination and use thereof
|
|
AU2022281461A1
(en)
|
2021-05-25 |
2024-01-04 |
Edelweiss Immune Inc |
C-x-c motif chemokine receptor 6 (cxcr6) binding molecules, and methods of using the same
|
|
BR112023024775A2
(pt)
|
2021-05-26 |
2024-02-15 |
Ct Inmunologia Molecular |
Uso de uma composição terapêutica, e, método de estratificação de pacientes
|
|
TW202307210A
(zh)
|
2021-06-01 |
2023-02-16 |
瑞士商諾華公司 |
Cd19和cd22嵌合抗原受體及其用途
|
|
EP4346904A1
(en)
|
2021-06-03 |
2024-04-10 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and cetuximab
|
|
WO2023280790A1
(en)
|
2021-07-05 |
2023-01-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
IL310201A
(en)
|
2021-07-19 |
2024-03-01 |
Regeneron Pharma |
Combination of inhibitor-control inhibitor and oncolytic virus for cancer treatment
|
|
JP2024529502A
(ja)
|
2021-07-30 |
2024-08-06 |
オーエヌエー セラピューティクス エセ.エレ. |
抗cd36抗体及び癌を治療するためのそれらの使用
|
|
JP2024528217A
(ja)
|
2021-08-03 |
2024-07-26 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性抗体および使用方法
|
|
WO2023015198A1
(en)
|
2021-08-04 |
2023-02-09 |
Genentech, Inc. |
Il15/il15r alpha heterodimeric fc-fusion proteins for the expansion of nk cells in the treatment of solid tumours
|
|
EP4396229A1
(en)
|
2021-09-02 |
2024-07-10 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Anti-cecam6 antibodies with reduced side-effects
|
|
AU2022341239A1
(en)
|
2021-09-08 |
2024-03-21 |
Redona Therapeutics, Inc. |
Papd5 and/or papd7 inhibiting 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivatives
|
|
TW202327595A
(zh)
|
2021-10-05 |
2023-07-16 |
美商輝瑞大藥廠 |
用於治療癌症之氮雜內醯胺化合物的組合
|
|
KR20240099331A
(ko)
|
2021-10-28 |
2024-06-28 |
라이엘 이뮤노파마, 인크. |
면역 세포를 배양하기 위한 방법
|
|
WO2023079428A1
(en)
|
2021-11-03 |
2023-05-11 |
Pfizer Inc. |
Combination therapies using tlr7/8 agonist
|
|
EP4433504A1
(en)
|
2021-11-17 |
2024-09-25 |
Institut National de la Santé et de la Recherche Médicale |
Universal sarbecovirus vaccines
|
|
IL313439A
(en)
|
2021-12-16 |
2024-08-01 |
Valerio Therapeutics |
New conjugated nucleic acid molecules and their uses
|
|
EP4452327A1
(en)
|
2021-12-20 |
2024-10-30 |
Synthorx, Inc. |
Head and neck cancer combination therapy comprising an il-2 conjugate and pembrolizumab
|
|
US20250099542A1
(en)
|
2021-12-30 |
2025-03-27 |
Neoimmunetech, Inc. |
Method of treating a tumor with a combination of il-7 protein and vegf antagonist
|
|
EP4460520A1
(en)
|
2022-01-07 |
2024-11-13 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating recurrent ovarian cancer with bispecific anti-muc16 x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
|
|
CN114432441B
(zh)
*
|
2022-01-11 |
2023-04-25 |
中国人民解放军陆军军医大学第一附属医院 |
一种pd-1修饰的金复合硒化铜纳米粒子及其在介导光热靶向治疗癌症方面的应用
|
|
CA3243281A1
(en)
|
2022-01-28 |
2023-08-03 |
Georgiamune Inc. |
ANTIBODIES DIRECTED AGAINST PROGRAMMED CELL DEATH PROTEIN 1 PD-1 AGONISTS
|
|
WO2023142996A1
(zh)
|
2022-01-28 |
2023-08-03 |
上海岸阔医药科技有限公司 |
预防或治疗与抗肿瘤剂相关的疾病或病症的方法
|
|
WO2023154799A1
(en)
|
2022-02-14 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Combination immunotherapy for treating cancer
|
|
EP4479388A1
(en)
|
2022-02-14 |
2024-12-25 |
Gilead Sciences, Inc. |
Antiviral naphthyridinone compounds
|
|
US20250152643A1
(en)
|
2022-02-17 |
2025-05-15 |
Regeneron Pharmaceuticals, Inc. |
Combinations of checkpoint inhibitors and oncolytic virus for treating cancer
|
|
KR20240150493A
(ko)
|
2022-02-21 |
2024-10-15 |
온퀄리티 파마슈티컬스 차이나 리미티드 |
화합물 및 그 용도
|
|
EP4482947A1
(en)
|
2022-02-24 |
2025-01-01 |
Amazentis SA |
Uses of urolithins
|
|
AU2023236126A1
(en)
|
2022-03-17 |
2024-09-19 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating recurrent epithelioid sarcoma with bispecific anti-muc16 x anti-cd3 antibodies alone or in combination with anti-pd-1 antibodies
|
|
WO2023192478A1
(en)
|
2022-04-01 |
2023-10-05 |
Bristol-Myers Squibb Company |
Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer
|
|
WO2023196988A1
(en)
|
2022-04-07 |
2023-10-12 |
Modernatx, Inc. |
Methods of use of mrnas encoding il-12
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
CA3253070A1
(en)
|
2022-05-16 |
2023-11-23 |
Regeneron Pharmaceuticals, Inc. |
TREATMENT METHODS FOR METASTATIC CASTRATION-RESISTANT PROSTATE CANCER WITH BISPECIFIC ANTI-CD3 AND ANTI-PSMA ANTIBODIES ALONE OR IN COMBINATION WITH ANTI-PD-1 ANTIBODIES
|
|
WO2023230554A1
(en)
|
2022-05-25 |
2023-11-30 |
Pfizer Inc. |
Combination of a braf inhibitor, an egfr inhibitor, and a pd-1 antagonist for the treatment of braf v600e-mutant, msi-h/dmmr colorectal cancer
|
|
JP2025523406A
(ja)
|
2022-06-09 |
2025-07-23 |
ザイメディ カンパニー リミテッド |
免疫増強活性を有する新規crs断片ペプチド及びその使用
|
|
US20250230256A1
(en)
|
2022-06-16 |
2025-07-17 |
Lamkap Bio Beta Ltd |
Combination therapy of bispecific antibodies against ceacam5 and cd47 and bispecific antibodies against ceacam5 and cd3
|
|
EP4543923A1
(en)
|
2022-06-22 |
2025-04-30 |
Juno Therapeutics, Inc. |
Treatment methods for second line therapy of cd19-targeted car t cells
|
|
CA3261612A1
(en)
|
2022-07-11 |
2024-01-18 |
Autonomous Therapeutics, Inc. |
Encrypted RNA and its methods of use
|
|
JP2025530983A
(ja)
|
2022-08-02 |
2025-09-19 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
二重特異性抗psma×抗cd28抗体を抗pd-1抗体と組み合わせて、転移性去勢抵抗性前立腺癌を治療する方法
|
|
KR20250047766A
(ko)
|
2022-08-05 |
2025-04-04 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Gprc5d 및 bcma에 특이적인 키메라 항원 수용체
|
|
JP2025527578A
(ja)
|
2022-08-18 |
2025-08-22 |
パルマトリックス オペレーティング カンパニー,インコーポレイテッド |
吸入用血管新生阻害剤を用いてがんを治療する方法
|
|
WO2024040264A1
(en)
|
2022-08-19 |
2024-02-22 |
Massachusetts Institute Of Technology |
Compositions and methods for targeting dendritic cell lectins
|
|
EP4583860A1
(en)
|
2022-09-06 |
2025-07-16 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
|
KR20250099774A
(ko)
|
2022-10-03 |
2025-07-02 |
리제너론 파아마슈티컬스, 인크. |
이중특이적 egfr x cd28 항체를 단독으로 또는 항-pd-1 항체와 조합하여 사용하여 암을 치료하는 방법
|
|
EP4602078A2
(en)
|
2022-10-11 |
2025-08-20 |
Yale University |
Compositions and methods of using cell-penetrating antibodies
|
|
JP2026504619A
(ja)
|
2022-11-07 |
2026-02-06 |
ネオイミューンテック, インコーポレイテッド |
非メチル化mgmtプロモーターを含む腫瘍を治療する方法
|
|
CN120569191A
(zh)
|
2022-11-23 |
2025-08-29 |
乔治亚大学研究基金公司 |
用于增加免疫应答的组合物及其使用方法
|
|
WO2024129778A2
(en)
|
2022-12-13 |
2024-06-20 |
Juno Therapeutics, Inc. |
Chimeric antigen receptors specific for baff-r and cd19 and methods and uses thereof
|
|
JP2026505276A
(ja)
|
2023-01-31 |
2026-02-13 |
ユニバーシティ オブ ロチェスター |
Staphylococcus aureus感染症を治療するための免疫チェックポイント遮断療法
|
|
AU2024234840A1
(en)
|
2023-03-13 |
2025-09-04 |
Regeneron Pharmaceuticals, Inc. |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating melanoma
|
|
WO2024215787A1
(en)
|
2023-04-11 |
2024-10-17 |
Ngm Biopharmaceuticals, Inc. |
Methods of treating osteosarcoma using lair1 binding agents and pd-1 antagonists
|
|
WO2024216028A1
(en)
|
2023-04-12 |
2024-10-17 |
Agenus Inc. |
Methods of treating cancer using an anti-ctla4 antibody and an enpp1 inhibitor
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
EP4701650A2
(en)
|
2023-04-26 |
2026-03-04 |
Isabella Pharma B.V. |
Methods of treating cancer by administering immunogenic compositions and a pd-1 inhibitor
|
|
WO2024261302A1
(en)
|
2023-06-22 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Nlrp3 inhibitors, pak1/2 inhibitors and/or caspase 1 inhibitors for use in the treatment of rac2 monogenic disorders
|
|
WO2025003193A1
(en)
|
2023-06-26 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Sertraline and indatraline for disrupting intracellular cholesterol trafficking and subsequently inducing lysosomal damage and anti-tumor immunity
|
|
WO2025006811A1
(en)
|
2023-06-27 |
2025-01-02 |
Lyell Immunopharma, Inc. |
Methods for culturing immune cells
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025021073A1
(zh)
|
2023-07-21 |
2025-01-30 |
江苏迈威康新药研发有限公司 |
抗Nectin4抗体药物偶联物和抗PD-1抗体的药物组合以及其用途
|
|
WO2025030041A1
(en)
|
2023-08-02 |
2025-02-06 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating metastatic castration-resistant prostate cancer with bispecific anti-psma x anti-cd28 antibodies
|
|
WO2025030044A1
(en)
|
2023-08-02 |
2025-02-06 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating clear cell renal cell carcinoma with bispecific anti-psma x anti-cd28 antibodies
|
|
CN121712524A
(zh)
|
2023-08-18 |
2026-03-20 |
百时美施贵宝公司 |
包含结合bcma和cd3的抗体的组合物以及治疗方法
|
|
WO2025051895A1
(en)
|
2023-09-06 |
2025-03-13 |
Novimmune Sa |
Combination therapy with a cea x cd28 bispecific antibody and blocking anti-pd-1 antibodies for enhanced in vivo anti-tumor activity
|
|
US20250114468A1
(en)
|
2023-10-09 |
2025-04-10 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating cancer with a combination of a pd1 inhibitor and a targeted immunocytokine
|
|
WO2025106736A2
(en)
|
2023-11-15 |
2025-05-22 |
Regeneron Pharmaceuticals, Inc. |
Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating lung cancer
|
|
TW202539732A
(zh)
|
2023-11-29 |
2025-10-16 |
美商再生元醫藥公司 |
以雙特異性抗muc16×抗cd28抗體與抗pd-1抗體之組合或與雙特異性抗muc16×抗cd3抗體之組合治療復發性卵巢癌及子宮內膜癌之方法
|
|
TW202542187A
(zh)
|
2023-12-12 |
2025-11-01 |
美商再生元醫藥公司 |
以雙特異性抗muc16x抗cd3抗體單獨或與抗pd-1抗體組合治療子宮內膜癌之方法
|
|
WO2025151487A2
(en)
|
2024-01-08 |
2025-07-17 |
Regents Of The University Of Michigan |
Small-molecule inhibitors of adar1
|
|
WO2025151800A1
(en)
|
2024-01-10 |
2025-07-17 |
Autonomous Therapeutics, Inc. |
Programmable, rna editor-controlled nucleic acid dose amplifiers and their methods of use
|
|
WO2025151803A1
(en)
|
2024-01-10 |
2025-07-17 |
Autonomous Therapeutics, Inc. |
Alphaviral encrypted rnas and their methods of use
|
|
WO2025210175A1
(en)
|
2024-04-04 |
2025-10-09 |
Centre National De La Recherche Scientifique |
Mutant csf-1r extracellular domain fusion molecules and therapeutic uses thereof
|
|
WO2025250689A1
(en)
*
|
2024-05-28 |
2025-12-04 |
Georgia State University Research Foundation |
Combination therapy with angiogenesis protein and immune checkpoint inhibitor with/without chemotherapeutics
|
|
WO2026003224A2
(en)
|
2024-06-26 |
2026-01-02 |
Iomx Therapeutics Ag |
Bispecific antigen binding proteins (abp) targeting immune checkpoint molecules and both leukocyte immunoglobulin-like receptor subfamily b1 (lilrb1) and lilrb2; combinations and uses thereof
|
|
WO2026006604A1
(en)
|
2024-06-26 |
2026-01-02 |
Lyell Immunopharma, Inc. |
Feeder cell replacement
|
|
WO2026012976A1
(en)
|
2024-07-08 |
2026-01-15 |
Institut National de la Santé et de la Recherche Médicale |
Use of inhibitor of gasdermind for treatment of rac2 monogenic disorders
|
|
WO2026015612A1
(en)
|
2024-07-10 |
2026-01-15 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating smarcb1-deficient cancers
|
|
WO2026037841A1
(en)
|
2024-08-12 |
2026-02-19 |
ONA Therapeutics S.L. |
Anti-fgfr4 molecules and uses thereof
|
|
WO2026050572A2
(en)
|
2024-08-29 |
2026-03-05 |
Marengo Therapeutics, Inc. |
Multifunctional molecules binding to tcr and uses thereof
|
|
WO2026052851A2
(en)
|
2024-09-09 |
2026-03-12 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitor of ciliogenesis for use in a method of preventing therapeutic resistance in cancer
|
|
WO2026059920A1
(en)
|
2024-09-10 |
2026-03-19 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating multiple myeloma with bcma inhibitors in combination with pd1/pd-l1 inhibitors
|