PL361172A1 - 1,3-Dioksolany o działaniu przeciwkaszlowym - Google Patents

1,3-Dioksolany o działaniu przeciwkaszlowym

Info

Publication number
PL361172A1
PL361172A1 PL36117201A PL36117201A PL361172A1 PL 361172 A1 PL361172 A1 PL 361172A1 PL 36117201 A PL36117201 A PL 36117201A PL 36117201 A PL36117201 A PL 36117201A PL 361172 A1 PL361172 A1 PL 361172A1
Authority
PL
Poland
Prior art keywords
dioxolanes
antitussive activity
preparation
acetals
antitussive
Prior art date
Application number
PL36117201A
Other languages
English (en)
Other versions
PL206307B1 (pl
Inventor
Marcello Allegretti
Maria Candida Cesta
Roberto Curti
Luigi Pellegrini
Gabriella Melillo
Original Assignee
Dompe S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe S.P.A. filed Critical Dompe S.P.A.
Publication of PL361172A1 publication Critical patent/PL361172A1/pl
Publication of PL206307B1 publication Critical patent/PL206307B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glass Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
PL361172A 2000-07-28 2001-07-18 2,2-podstawione 1,3-dioksolany, sposób ich wytwarzania, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie PL206307B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI001734A IT1318650B1 (it) 2000-07-28 2000-07-28 1,3-diossolani ad attivita' antitosse.

Publications (2)

Publication Number Publication Date
PL361172A1 true PL361172A1 (pl) 2004-09-20
PL206307B1 PL206307B1 (pl) 2010-07-30

Family

ID=11445591

Family Applications (1)

Application Number Title Priority Date Filing Date
PL361172A PL206307B1 (pl) 2000-07-28 2001-07-18 2,2-podstawione 1,3-dioksolany, sposób ich wytwarzania, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie

Country Status (26)

Country Link
US (1) US6835734B2 (pl)
EP (1) EP1307441B1 (pl)
JP (1) JP5107497B2 (pl)
KR (1) KR100781403B1 (pl)
CN (1) CN1204135C (pl)
AT (1) ATE266018T1 (pl)
AU (1) AU2001287638A1 (pl)
BR (1) BR0112765A (pl)
CZ (1) CZ301087B6 (pl)
DE (1) DE60103164T2 (pl)
DK (1) DK1307441T3 (pl)
EE (1) EE05178B1 (pl)
ES (1) ES2219562T3 (pl)
HU (1) HUP0301497A3 (pl)
IL (2) IL153515A0 (pl)
IT (1) IT1318650B1 (pl)
MX (1) MXPA02012920A (pl)
PL (1) PL206307B1 (pl)
PT (1) PT1307441E (pl)
RS (1) RS50861B (pl)
RU (1) RU2276149C2 (pl)
SI (1) SI21040A (pl)
SK (1) SK286794B6 (pl)
TR (1) TR200401315T4 (pl)
UA (1) UA73789C2 (pl)
WO (1) WO2002010149A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318651B1 (it) * 2000-07-28 2003-08-27 Dompe Spa Sintesi di (+-)1,3-diossolani e loro risoluzione ottica.
TWI496776B (zh) * 2007-11-15 2015-08-21 Astrazeneca Ab 製備(3aR,4S,6R,6aS)-6-胺基-2,2-二甲基四氫-3aH-環戊并[d][1,3]二氧雜環戊烯-4-醇之純非對映異構性之二苯甲醯-L-酒石酸鹽之方法
EP2070915A1 (en) * 2007-12-03 2009-06-17 A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. New process for the synthesis of moguisteine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049660A (en) * 1971-06-18 1977-09-20 Delalande S.A. N-substituted derivatives of 4 (N-piperazinylmethyl) spiro dibenzocycloheptadi- (or tri-) ene-5, 2-dioxolane (1,3) their method of preparation and their application in therapeutics
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono
NL8801622A (nl) * 1988-06-25 1990-01-16 Stamicarbon Bereiding van enantiomeren van dropropizine.
IT1226570B (it) * 1988-08-01 1991-01-24 Bidachem Spa Procedimento di preparazione della levo- e destro-dropropizina
DE4041482A1 (de) * 1990-12-22 1992-06-25 Boehringer Ingelheim Kg Neue pharmazeutische verwendung carbocyclisch und heterocyclisch annelierter dihydropyridine
IT1254452B (it) * 1992-02-14 1995-09-25 Dompe Farmaceutici Spa N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli
IT1254993B (it) * 1992-06-24 1995-10-11 Procedimento per la preparazione degli enantiomeri della dropropizina
IL111730A (en) * 1993-11-29 1998-12-06 Fujisawa Pharmaceutical Co Piperazine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
IT1318651B1 (it) * 2000-07-28 2003-08-27 Dompe Spa Sintesi di (+-)1,3-diossolani e loro risoluzione ottica.

Also Published As

Publication number Publication date
PT1307441E (pt) 2004-09-30
RS50861B (sr) 2010-08-31
HUP0301497A2 (hu) 2003-09-29
TR200401315T4 (tr) 2004-07-21
UA73789C2 (en) 2005-09-15
US20040038989A1 (en) 2004-02-26
YU3003A (sh) 2006-05-25
HK1058797A1 (en) 2004-06-04
EE200300036A (et) 2004-10-15
SI21040A (sl) 2003-04-30
HUP0301497A3 (en) 2005-08-29
EE05178B1 (et) 2009-06-15
EP1307441A1 (en) 2003-05-07
AU2001287638A1 (en) 2002-02-13
BR0112765A (pt) 2004-01-13
MXPA02012920A (es) 2004-04-20
DK1307441T3 (da) 2004-08-09
JP2004505073A (ja) 2004-02-19
CZ2003268A3 (cs) 2003-06-18
CN1204135C (zh) 2005-06-01
WO2002010149A1 (en) 2002-02-07
IL153515A0 (en) 2003-07-06
IL153515A (en) 2006-12-10
JP5107497B2 (ja) 2012-12-26
US6835734B2 (en) 2004-12-28
RU2276149C2 (ru) 2006-05-10
CZ301087B6 (cs) 2009-11-04
DE60103164T2 (de) 2005-05-04
KR100781403B1 (ko) 2007-12-03
ITMI20001734A0 (it) 2000-07-28
ITMI20001734A1 (it) 2002-01-28
SK892003A3 (en) 2003-09-11
ATE266018T1 (de) 2004-05-15
DE60103164D1 (de) 2004-06-09
EP1307441B1 (en) 2004-05-06
ES2219562T3 (es) 2004-12-01
PL206307B1 (pl) 2010-07-30
CN1444578A (zh) 2003-09-24
SK286794B6 (sk) 2009-05-07
KR20030016425A (ko) 2003-02-26
IT1318650B1 (it) 2003-08-27

Similar Documents

Publication Publication Date Title
DE69015650D1 (de) Herstellung von diamantverbundbeschichteten Schneidwerkzeugen.
TW200514783A (en) Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method
DE69022075D1 (de) Handwerkzeugmaschine zur Herstellung von kreisabschnittförmigen Nuten.
EA200101156A1 (ru) ЛЕКАРСТВЕННЫЕ КОМПОЗИЦИИ НОВОГО ТИПА НА ОСНОВЕ ОБЛАДАЮЩИХ ХОЛИНЕРГИЧЕСКИМ ДЕЙСТВИЕМ СОЕДИНЕНИЙ И β-МИМЕТИКОВ
EA200300459A1 (ru) Новые, применяемые в качестве медикаментов антихолинергические средства, а также способ их получения
ATE288414T1 (de) Herstellung von 2-amino-2(2-(4- alkylphenyl)äthyl)propan-1,3-diolen
ATE202483T1 (de) Immuntolerante prothrombinkomplex-präparation
NL950021I2 (nl) 2-(Difluormethoxy)-1,1,1,2-tretrafluorethaan als anestheticum.
SE9804002D0 (sv) New manufacturing process
CA2256514A1 (en) Veterinary use of a pleuromutilin derivative
EA199901098A1 (ru) Новый способ
IL153515A0 (en) 1,3-dioxolanes with antitussive activity
IT1293777B1 (it) Processo per la preparazione di tetraazamacrocicli
IL153502A0 (en) 2,2-disubstituted 1,3-dioxolanes as antitussive agents
FI916018A7 (fi) 1,3-dioksolaanijohdannaisia kolesterolia alentavina aineina
EA200100864A1 (ru) Способ получения 1,4,7,10-тетраазациклододекана
HU9904315D0 (en) Process for preparing orthoesters
IT9020200A0 (it) Procedimento per la fabbricazione di spazzole, nonche' macchina per la fabbricazione di spazzole per l'esecuzione del procedimento
SE9900693D0 (sv) Novel process
IT1309222B1 (it) Struttura di macchina utensile perfezionata.
ITMI992247A0 (it) Macchina i.s.

Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20120718