PL400683A1 - Sekwencja DNA oraz sposób otrzymywania rekombinowanego alergenu pylku traw PHL P4 - Google Patents

Sekwencja DNA oraz sposób otrzymywania rekombinowanego alergenu pylku traw PHL P4

Info

Publication number
PL400683A1
PL400683A1 PL400683A PL40068303A PL400683A1 PL 400683 A1 PL400683 A1 PL 400683A1 PL 400683 A PL400683 A PL 400683A PL 40068303 A PL40068303 A PL 40068303A PL 400683 A1 PL400683 A1 PL 400683A1
Authority
PL
Poland
Prior art keywords
dna
encoding
phl
poaceae
polypeptide
Prior art date
Application number
PL400683A
Other languages
English (en)
Other versions
PL219272B1 (pl
Inventor
Helmut Fiebig
Andreas Nandy
Roland Suck
Oliver Cromwell
Arnd Petersen
Wolf-Meinhard Becker
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29797135&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL400683(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL400683A1 publication Critical patent/PL400683A1/pl
Publication of PL219272B1 publication Critical patent/PL219272B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL400683A 2002-06-25 2003-06-11 Sekwencja DNA oraz sposób otrzymywania rekombinowanego alergenu pyłku traw Phl p4 PL219272B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02013953 2002-06-25

Publications (2)

Publication Number Publication Date
PL400683A1 true PL400683A1 (pl) 2013-02-04
PL219272B1 PL219272B1 (pl) 2015-04-30

Family

ID=29797135

Family Applications (2)

Application Number Title Priority Date Filing Date
PL372423A PL215097B1 (pl) 2002-06-25 2003-06-11 Czasteczka DNA, zawierajacy ja rekombinowany wektor ekspresyjny DNA, organizm zywiciela transformowany taka czasteczka lub wektorem oraz polipeptyd kodowany przez sekwencje takiej czasteczki DNA o wlasciwosciach glównego alergenu pylku Phl p 4 z Phleum pratense
PL400683A PL219272B1 (pl) 2002-06-25 2003-06-11 Sekwencja DNA oraz sposób otrzymywania rekombinowanego alergenu pyłku traw Phl p4

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL372423A PL215097B1 (pl) 2002-06-25 2003-06-11 Czasteczka DNA, zawierajacy ja rekombinowany wektor ekspresyjny DNA, organizm zywiciela transformowany taka czasteczka lub wektorem oraz polipeptyd kodowany przez sekwencje takiej czasteczki DNA o wlasciwosciach glównego alergenu pylku Phl p 4 z Phleum pratense

Country Status (13)

Country Link
US (3) US8128935B2 (pl)
EP (2) EP2392591B1 (pl)
JP (1) JP2006510346A (pl)
CN (1) CN100391970C (pl)
AT (1) ATE550349T1 (pl)
AU (1) AU2003279352B2 (pl)
BR (1) BR0312068A (pl)
CA (1) CA2491038C (pl)
ES (2) ES2384045T3 (pl)
PL (2) PL215097B1 (pl)
PT (2) PT1515988E (pl)
RU (1) RU2327739C2 (pl)
WO (1) WO2004000881A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10359352A1 (de) 2003-12-16 2005-07-21 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung des Graspollen-Allergens Lol p 4
DE10359351A1 (de) 2003-12-16 2005-07-21 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden
AU2013204574B2 (en) * 2003-12-16 2015-02-26 Merck Patent Gmbh DNA-sequence and recombinant production of group 4 major allergens from cereals
AU2011202726B2 (en) * 2003-12-16 2012-04-26 Merck Patent Gmbh DNA-sequence and recombinant production of group 4 major allergens from cereals
EP2523684A1 (de) * 2010-01-14 2012-11-21 Merck Patent GmbH Varianten der gruppe 6-allergene der süssgräser mit reduzierter allergenität durch mutagenese von prolinresten
BR112014019504A2 (pt) * 2012-02-07 2017-06-27 La Jolla Inst Allergy & Immunology alérgenos da erva-dos-prados e métodos e usos para modulação de resposta imune

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030135888A1 (en) * 2001-09-26 2003-07-17 Tong Zhu Genes that are modulated by posttranscriptional gene silencing

Also Published As

Publication number Publication date
EP1515988A1 (de) 2005-03-23
US20060177470A1 (en) 2006-08-10
JP2006510346A (ja) 2006-03-30
CA2491038A1 (en) 2003-12-31
ES2670573T3 (es) 2018-05-31
CA2491038C (en) 2017-04-25
AU2003279352A1 (en) 2004-01-06
AU2003279352B2 (en) 2009-09-10
RU2005101744A (ru) 2005-06-27
EP1515988B1 (de) 2012-03-21
PL215097B1 (pl) 2013-10-31
US20120288526A1 (en) 2012-11-15
US9556241B2 (en) 2017-01-31
EP2392591B1 (de) 2018-02-21
PT2392591T (pt) 2018-05-23
PL219272B1 (pl) 2015-04-30
CN100391970C (zh) 2008-06-04
WO2004000881A1 (de) 2003-12-31
EP2392591A1 (de) 2011-12-07
CN1665835A (zh) 2005-09-07
US20150079120A1 (en) 2015-03-19
US8128935B2 (en) 2012-03-06
RU2327739C2 (ru) 2008-06-27
WO2004000881A9 (de) 2004-02-26
US9120866B2 (en) 2015-09-01
PT1515988E (pt) 2012-06-25
ES2384045T3 (es) 2012-06-28
PL372423A1 (pl) 2005-07-25
ATE550349T1 (de) 2012-04-15
BR0312068A (pt) 2005-03-29

Similar Documents

Publication Publication Date Title
US9346860B2 (en) Expression system
AU2007271350B2 (en) Small Streptococcus pyogenes antigens and their use
CN100460014C (zh) 基于尿素酶b亚单位活性片段的幽门螺杆菌疫苗及其制备方法
US20100310472A1 (en) Dna sequence, and recombinant preparation of the grass pollen allergen lol p 4
Ohashi et al. Cloning and sequencing of the gene (tsg56) encoding a type-specific antigen from Rickettsia tsutsugamushi
SE0000514D0 (sv) A 52 kDa protein from coagulase negative staphylococci and fragments
KR20070029708A (ko) 스타필로코커스 아우레우스의 변형 피브로넥틴-결합 단백질
BR0312068A (pt) Sequência de dna e preparação de alérgeno de pólen de gramìneas phl p 4 por métodos recombinantes
CN110746496B (zh) 一种鲍曼不动杆菌的pal重组蛋白及其编码基因和它们的应用
TW200716166A (en) Lawsonia intracellularis immunological proteins
CA2370393A1 (en) Dna sequence, and recombinant production of a gramineae allergen
US8263090B2 (en) Variants of group 1 allergens from Poaceae having reduced allergenicity and maintained T-cell reactivity
DE502004012294D1 (de) Dna-sequenz und rekombinante herstellung von gruppe-4 majorallergenen aus getreiden
ATE513848T1 (de) Phl p 5a-derivate mit reduzierter allergenität und erhaltener t-zellreaktivität
HK1004569A1 (en) Novel vaccine
JP6039648B2 (ja) 併用ワクチン
AU2013203639A1 (en) Small streptococcus pyogenes antiens and their use