PT1073647E - Derivados de 12,13-ciclopropano-epotilona - Google Patents

Derivados de 12,13-ciclopropano-epotilona Download PDF

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Publication number
PT1073647E
PT1073647E PT99915273T PT99915273T PT1073647E PT 1073647 E PT1073647 E PT 1073647E PT 99915273 T PT99915273 T PT 99915273T PT 99915273 T PT99915273 T PT 99915273T PT 1073647 E PT1073647 E PT 1073647E
Authority
PT
Portugal
Prior art keywords
epothilone derivatives
cyclopropane
cyclopropane epothilone
derivatives
epothilone
Prior art date
Application number
PT99915273T
Other languages
English (en)
Inventor
Gregory D Vite
Gerhard Hofle
Soong-Hoon Kim Kim
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PT1073647E publication Critical patent/PT1073647E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT99915273T 1998-04-21 1999-04-05 Derivados de 12,13-ciclopropano-epotilona PT1073647E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8256498P 1998-04-21 1998-04-21

Publications (1)

Publication Number Publication Date
PT1073647E true PT1073647E (pt) 2009-07-17

Family

ID=22171978

Family Applications (3)

Application Number Title Priority Date Filing Date
PT50152362T PT1589017E (pt) 1998-04-21 1999-04-05 Derivados de epotilona modificados na posição 12,13
PT99915273T PT1073647E (pt) 1998-04-21 1999-04-05 Derivados de 12,13-ciclopropano-epotilona
PT99916383T PT1073648E (pt) 1998-04-21 1999-04-05 Derivados de epotilona modificados em 12, 13

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT50152362T PT1589017E (pt) 1998-04-21 1999-04-05 Derivados de epotilona modificados na posição 12,13

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT99916383T PT1073648E (pt) 1998-04-21 1999-04-05 Derivados de epotilona modificados em 12, 13

Country Status (17)

Country Link
US (2) US6399638B1 (pt)
EP (3) EP1073647B1 (pt)
JP (2) JP2002512238A (pt)
CN (1) CN1142923C (pt)
AR (2) AR015007A1 (pt)
AT (2) ATE340177T1 (pt)
AU (2) AU748526B2 (pt)
BR (1) BR9909795A (pt)
CA (2) CA2329181C (pt)
CY (2) CY1105836T1 (pt)
DE (2) DE69933287T2 (pt)
DK (3) DK1589017T3 (pt)
ES (3) ES2400049T3 (pt)
PE (1) PE20000460A1 (pt)
PT (3) PT1589017E (pt)
TR (1) TR200003036T2 (pt)
WO (2) WO1999054319A1 (pt)

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Also Published As

Publication number Publication date
DK1589017T3 (da) 2013-03-18
DE69933287D1 (de) 2006-11-02
ATE435861T1 (de) 2009-07-15
AR015774A1 (es) 2001-05-16
US6399638B1 (en) 2002-06-04
ES2327803T3 (es) 2009-11-03
DE69933287T2 (de) 2007-05-03
PE20000460A1 (es) 2000-06-09
EP1073648B1 (en) 2006-09-20
CA2329181A1 (en) 1999-10-28
CY1105836T1 (el) 2011-02-02
EP1073647A1 (en) 2001-02-07
CA2329181C (en) 2011-02-22
PT1073648E (pt) 2006-12-29
JP4476483B2 (ja) 2010-06-09
PT1589017E (pt) 2013-03-04
CN1298398A (zh) 2001-06-06
DK1073647T3 (da) 2009-11-09
ATE340177T1 (de) 2006-10-15
US6380395B1 (en) 2002-04-30
AU757733B2 (en) 2003-03-06
EP1073647B1 (en) 2009-07-08
EP1073648A1 (en) 2001-02-07
TR200003036T2 (tr) 2001-01-22
AR015007A1 (es) 2001-04-11
EP1073648A4 (en) 2003-01-02
CN1142923C (zh) 2004-03-24
JP2002512239A (ja) 2002-04-23
DK1073648T3 (da) 2007-01-08
AU748526B2 (en) 2002-06-06
ES2273484T3 (es) 2007-05-01
CY1109593T1 (el) 2014-08-13
JP2002512238A (ja) 2002-04-23
AU3471699A (en) 1999-11-08
EP1073647A4 (en) 2003-01-02
EP1589017A2 (en) 2005-10-26
BR9909795A (pt) 2000-12-26
AU3382799A (en) 1999-11-08
WO1999054318A1 (en) 1999-10-28
EP1589017B1 (en) 2012-12-05
WO1999054319A1 (en) 1999-10-28
DE69941083D1 (en) 2009-08-20
CA2323609A1 (en) 1999-10-28
ES2400049T3 (es) 2013-04-05
EP1589017A3 (en) 2009-04-22

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