PT92952A - Processo para a preparacao de acidos 3-fenil-5,6-di-hidrobenz { c }acridina-7- carboxilicos, de compostos relacionados e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de acidos 3-fenil-5,6-di-hidrobenz { c }acridina-7- carboxilicos, de compostos relacionados e de composicoes farmaceuticas que os contem

Info

Publication number: PT92952A
Authority: PT; Portugal
Prior art keywords: dihydrobenz; acridine; preparation; pharmaceutical compositions; phenyl
Prior art date: 1989-01-25

Application number

PT92952A

Other languages

English (en)

Other versions

PT92952B (pt

Inventor

Carl Henry Behrens

Original Assignee

Du Pont Merck Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-25

Filing date

1990-01-24

Publication date

1990-07-31

1990-01-24 Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma

1990-07-31 Publication of PT92952A publication Critical patent/PT92952A/pt

1995-12-29 Publication of PT92952B publication Critical patent/PT92952B/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/02—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PT92952A 1989-01-25 1990-01-24 Processo para a preparacao de acidos 3-fenil-5,6-di-hidrobenz { c }acridina-7- carboxilicos, de compostos relacionados e de composicoes farmaceuticas que os contem PT92952B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/301,379 US4918077A (en)	1989-01-25	1989-01-25	3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents

Publications (2)

Publication Number	Publication Date
PT92952A true PT92952A (pt)	1990-07-31
PT92952B PT92952B (pt)	1995-12-29

Family

ID=23163099

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT92952A PT92952B (pt)	1989-01-25	1990-01-24	Processo para a preparacao de acidos 3-fenil-5,6-di-hidrobenz { c }acridina-7- carboxilicos, de compostos relacionados e de composicoes farmaceuticas que os contem

Country Status (21)

Country	Link
US (2)	US4918077A (pt)
EP (1)	EP0380038B1 (pt)
JP (1)	JPH0662572B2 (pt)
KR (1)	KR910006985B1 (pt)
AT (1)	ATE124399T1 (pt)
AU (1)	AU623481B2 (pt)
CA (1)	CA2007529A1 (pt)
DE (1)	DE69020368T2 (pt)
DK (1)	DK0380038T3 (pt)
ES (1)	ES2075074T3 (pt)
FI (1)	FI95374C (pt)
GR (1)	GR3016979T3 (pt)
HU (1)	HU205743B (pt)
IE (1)	IE68761B1 (pt)
IL (1)	IL93161A0 (pt)
MY (1)	MY104829A (pt)
NO (1)	NO176961C (pt)
NZ (1)	NZ232207A (pt)
PT (1)	PT92952B (pt)
RU (1)	RU1779247C (pt)
ZA (1)	ZA90545B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5135934A (en) *	1990-07-06	1992-08-04	Du Pont Merck Pharmaceutical Company	3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
EP0601191B1 (en) *	1992-04-24	1998-07-22	Kyowa Hakko Kogyo Kabushiki Kaisha	Novel tetracyclic compound
US5807549A (en) *	1993-05-21	1998-09-15	Research Corporation Technologies, Inc.	Lymphocyte chemoattractant factor and uses thereof
US5428040A (en) *	1993-08-31	1995-06-27	The Du Pont Merck Pharmaceutical Company	Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
DE69430752T2 (de) *	1993-09-28	2002-10-17	Kyowa Hakko Kogyo Co., Ltd.	Tetracyclische verbindungen
GB9400585D0 (en) *	1994-01-13	1994-03-09	Guest John D	Improvements in or relating to tube couplings
JP3141148B2 (ja) *	1995-08-08	2001-03-05	大鵬薬品工業株式会社	縮合インダン誘導体及びその塩
AU2896097A (en) *	1996-05-10	1997-12-05	Novartis Ag	Use of brequinar and derivatives in chronic rejection of allografts and xenotransplantation
US7847125B2 (en) *	2007-11-16	2010-12-07	Chemtura Corporation	Acridan derivatives as antioxidants
CN102351870B (zh) *	2011-08-25	2014-03-12	中山大学	一种苯并吖啶衍生物的制备方法及其作为抗癌药物的用途
WO2015077535A2 (en)	2013-11-22	2015-05-28	Genzyme Corporation	Novel methods for treating neurodegenerative diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE502610A (pt) *	1950-04-18
US4680299A (en) *	1984-04-30	1987-07-14	E.I. Du Pont De Nemours And Company	2-phenyl-4-quinolinecarboxylic acids and pharmaceutical compositions thereof
DE3483704D1 (de) *	1983-07-22	1991-01-17	Du Pont	Phenylchinolinsaeure und derivate als antitumormittel.
US4847381A (en) *	1987-08-31	1989-07-11	American Cyanamid Company	2-Phenyl-4-quinoline carboxylic acids

1989
- 1989-01-25 US US07/301,379 patent/US4918077A/en not_active Expired - Lifetime
1990
- 1990-01-10 CA CA002007529A patent/CA2007529A1/en not_active Abandoned
- 1990-01-23 ES ES90101253T patent/ES2075074T3/es not_active Expired - Lifetime
- 1990-01-23 EP EP90101253A patent/EP0380038B1/en not_active Expired - Lifetime
- 1990-01-23 DE DE69020368T patent/DE69020368T2/de not_active Expired - Fee Related
- 1990-01-23 AT AT90101253T patent/ATE124399T1/de not_active IP Right Cessation
- 1990-01-23 DK DK90101253.4T patent/DK0380038T3/da active
- 1990-01-23 NZ NZ232207A patent/NZ232207A/xx unknown
- 1990-01-24 HU HU90255A patent/HU205743B/hu not_active IP Right Cessation
- 1990-01-24 IE IE26790A patent/IE68761B1/en not_active IP Right Cessation
- 1990-01-24 IL IL93161A patent/IL93161A0/xx not_active IP Right Cessation
- 1990-01-24 JP JP2012772A patent/JPH0662572B2/ja not_active Expired - Lifetime
- 1990-01-24 NO NO900342A patent/NO176961C/no unknown
- 1990-01-24 PT PT92952A patent/PT92952B/pt not_active IP Right Cessation
- 1990-01-24 RU SU904742891A patent/RU1779247C/ru active
- 1990-01-24 FI FI900365A patent/FI95374C/fi not_active IP Right Cessation
- 1990-01-24 KR KR1019900000801A patent/KR910006985B1/ko not_active Expired
- 1990-01-25 ZA ZA90545A patent/ZA90545B/xx unknown
- 1990-01-25 AU AU48745/90A patent/AU623481B2/en not_active Ceased
- 1990-01-25 MY MYPI90000135A patent/MY104829A/en unknown
- 1990-02-01 US US07/473,507 patent/US5002954A/en not_active Expired - Fee Related
1995
- 1995-08-02 GR GR950402095T patent/GR3016979T3/el unknown

Also Published As

Publication number	Publication date
US5002954A (en)	1991-03-26
JPH02233661A (ja)	1990-09-17
EP0380038B1 (en)	1995-06-28
PT92952B (pt)	1995-12-29
GR3016979T3 (en)	1995-11-30
ZA90545B (en)	1991-09-25
NO176961C (no)	1995-06-28
NO900342L (no)	1990-07-26
AU623481B2 (en)	1992-05-14
NO900342D0 (no)	1990-01-24
DE69020368D1 (de)	1995-08-03
FI95374C (fi)	1996-01-25
RU1779247C (ru)	1992-11-30
IE900267L (en)	1990-07-25
MY104829A (en)	1994-06-30
NZ232207A (en)	1991-08-27
NO176961B (no)	1995-03-20
KR900011735A (ko)	1990-08-02
JPH0662572B2 (ja)	1994-08-17
US4918077A (en)	1990-04-17
CA2007529A1 (en)	1990-07-25
IE68761B1 (en)	1996-07-10
EP0380038A3 (en)	1991-11-13
KR910006985B1 (ko)	1991-09-14
AU4874590A (en)	1990-08-02
DE69020368T2 (de)	1995-11-09
IL93161A0 (en)	1990-11-05
FI900365A0 (fi)	1990-01-24
DK0380038T3 (da)	1995-08-28
ES2075074T3 (es)	1995-10-01
ATE124399T1 (de)	1995-07-15
EP0380038A2 (en)	1990-08-01
HUT53880A (en)	1990-12-28
FI95374B (fi)	1995-10-13
HU205743B (en)	1992-06-29
HU900255D0 (en)	1990-03-28

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Legal Events

Date

Code

Title

Description

1995-12-29

FG3A

Patent granted, date of granting

Effective date: 19950929

2000-07-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000331