PT95016A - Processo para a preparacao de peptidos terapeuticos - Google Patents

Processo para a preparacao de peptidos terapeuticos

Info

Publication number: PT95016A
Authority: PT; Portugal
Prior art keywords: amino acid; acid residue; peptide; active site; preparation
Prior art date: 1989-08-16

Application number

PT95016A

Other languages

English (en)

Other versions

PT95016B (pt

Original Assignee

Univ Tulane

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-16

Filing date

1990-08-16

Publication date

1991-04-18

1990-08-16 Application filed by Univ Tulane filed Critical Univ Tulane

1991-04-18 Publication of PT95016A publication Critical patent/PT95016A/pt

1997-05-28 Publication of PT95016B publication Critical patent/PT95016B/pt

Links

108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
102000004196 processed proteins & peptides Human genes 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
125000000539 amino acid group Chemical group 0.000 abstract 3
QDZOEBFLNHCSSF-PFFBOGFISA-N (2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2R)-2-amino-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide Chemical compound C([C@@H](C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](N)CCCNC(N)=N)C1=CC=CC=C1 QDZOEBFLNHCSSF-PFFBOGFISA-N 0.000 abstract 1
102100024304 Protachykinin-1 Human genes 0.000 abstract 1
101800003906 Substance P Proteins 0.000 abstract 1
150000001576 beta-amino acids Chemical class 0.000 abstract 1
229940088623 biologically active substance Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

PT95016A 1989-08-16 1990-08-16 Processo para a preparacao de peptidos terapeuticos PT95016B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US39472789A	1989-08-16	1989-08-16

Publications (2)

Publication Number	Publication Date
PT95016A true PT95016A (pt)	1991-04-18
PT95016B PT95016B (pt)	1997-05-28

Family

ID=23560172

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT95016A PT95016B (pt)	1989-08-16	1990-08-16	Processo para a preparacao de peptidos terapeuticos

Country Status (15)

Country	Link
EP (1)	EP0438566B1 (pt)
JP (1)	JPH04502922A (pt)
AT (1)	ATE143372T1 (pt)
CA (1)	CA2039175A1 (pt)
CZ (2)	CZ285562B6 (pt)
DD (1)	DD298411A5 (pt)
DE (1)	DE69028692T2 (pt)
DK (1)	DK0438566T3 (pt)
ES (1)	ES2094160T3 (pt)
GR (1)	GR900100613A (pt)
HU (1)	HUT65465A (pt)
IE (1)	IE77033B1 (pt)
PT (1)	PT95016B (pt)
SK (1)	SK402890A3 (pt)
WO (1)	WO1991002745A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5410019A (en) *	1987-09-24	1995-04-25	The Administrators Of The Tulane-Educational Fund	Therapeutic peptides
FR2680174A1 (fr) *	1991-08-05	1993-02-12	Michelot Robert	Nouveaux composes peptidiques, inhibiteurs de l'adsorption du virus hiv sur ses cellules cibles.
EP1082959A1 (en)	1991-09-20	2001-03-14	Glaxo Group Limited	NK1 Antagonists for the treatment of depression
US6156725A (en) *	1996-08-16	2000-12-05	National Institute Of Immunology	Drug for the treatment of cancer
US6492330B1 (en)	1996-08-16	2002-12-10	National Institute Of Immunology	Antiangiogenic drugs
EP0835662B1 (en) *	1996-10-08	2001-11-14	National Institute of Immunology	A drug for the treatment of cancer
CA2225185A1 (en)	1997-08-11	1999-02-11	Peter K. Law	Myoblast transfer therapy for relieving pain and for treating behavioral and perceptive abnormalities
US6316414B1 (en)	2000-07-31	2001-11-13	Dabur Research Foundation	Somatostatin analogs for the treatment of cancer
JP2010516731A (ja)	2007-01-24	2010-05-20	グラクソグループリミテッド	２−メトキシ−５−（５−トリフルオロメチル−テトラゾール−１−イル）−ベンジル］−（２ｓ−フェニル−ピペリジン−３ｓ−イル）−アミンを含む医薬組成物
JP5707101B2 (ja) *	2009-11-11	2015-04-22	国立大学法人山口大学	消化器疾患治療剤
US9446029B2 (en)	2010-07-27	2016-09-20	Colorado State University Research Foundation	Use of NK-1 receptor antagonists in management of visceral pain
WO2023139542A1 (en) *	2022-01-21	2023-07-27	Institut Pasteur De Montevideo	Active immunization for reducing osteoarthritic, neuropathic, and cancer pain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3862114A (en) *	1971-11-22	1975-01-21	Ici Australia Ltd	Analogs of substance p
IT1212508B (it) *	1981-12-22	1989-11-22	Anic Spa	Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori
US4481139A (en) *	1983-04-13	1984-11-06	Board Of Regents, The University Of Texas System	Peptide antagonists of substance P
US4803261A (en) *	1986-06-27	1989-02-07	The Administrators Of The Tulane Educational Fund	Method for synthesizing a peptide containing a non-peptide
NZ229552A (en) *	1988-06-20	1992-06-25	Merrell Dow Pharma	Neurokinin a antagonists

1990
- 1990-08-15 IE IE295890A patent/IE77033B1/en not_active IP Right Cessation
- 1990-08-16 SK SK4028-90A patent/SK402890A3/sk unknown
- 1990-08-16 CA CA002039175A patent/CA2039175A1/en not_active Abandoned
- 1990-08-16 CZ CZ99774A patent/CZ285562B6/cs not_active IP Right Cessation
- 1990-08-16 JP JP2511667A patent/JPH04502922A/ja active Pending
- 1990-08-16 PT PT95016A patent/PT95016B/pt not_active IP Right Cessation
- 1990-08-16 DK DK90912128.7T patent/DK0438566T3/da active
- 1990-08-16 ES ES90912128T patent/ES2094160T3/es not_active Expired - Lifetime
- 1990-08-16 HU HU906872A patent/HUT65465A/hu unknown
- 1990-08-16 DD DD90343501A patent/DD298411A5/de not_active IP Right Cessation
- 1990-08-16 EP EP90912128A patent/EP0438566B1/en not_active Expired - Lifetime
- 1990-08-16 GR GR900100613A patent/GR900100613A/el unknown
- 1990-08-16 DE DE69028692T patent/DE69028692T2/de not_active Expired - Fee Related
- 1990-08-16 AT AT90912128T patent/ATE143372T1/de not_active IP Right Cessation
- 1990-08-16 CZ CS904028A patent/CZ285319B6/cs not_active IP Right Cessation
- 1990-08-16 WO PCT/US1990/004633 patent/WO1991002745A1/en not_active Ceased

Also Published As

Publication number	Publication date
CZ285319B6 (cs)	1999-07-14
IE902958A1 (en)	1991-02-27
DD298411A5 (de)	1992-02-20
SK280796B6 (sk)	2000-07-11
PT95016B (pt)	1997-05-28
CZ285562B6 (cs)	1999-09-15
EP0438566B1 (en)	1996-09-25
HUT65465A (en)	1994-06-28
HU906872D0 (en)	1991-07-29
JPH04502922A (ja)	1992-05-28
ATE143372T1 (de)	1996-10-15
WO1991002745A1 (en)	1991-03-07
DE69028692D1 (de)	1996-10-31
EP0438566A4 (en)	1993-03-31
DK0438566T3 (da)	1996-11-11
EP0438566A1 (en)	1991-07-31
IE77033B1 (en)	1997-11-19
ES2094160T3 (es)	1997-01-16
GR900100613A (el)	1991-12-30
SK402890A3 (en)	2000-07-11
CZ402890A3 (cs)	1999-04-14
DE69028692T2 (de)	1997-02-20
CA2039175A1 (en)	1991-02-17

Legal Events

Date

Code

Title

Description

1991-04-18

BB1A

Laying open of patent application

Effective date: 19901226

1997-05-30

FG3A

Patent granted, date of granting

Effective date: 19970218

2001-12-28

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20010831

Publication	Publication Date	Title
ATE139540T1 (de)	1996-07-15	Heilmittelpeptide
DK66391A (da)	1991-06-14	Terapeutisk virksomme peptider
ES2124685T3 (es)	1999-02-16	Variantes del inhibidor de la tripsina pancreatica bovina, su produccion y uso.
ATE113961T1 (de)	1994-11-15	Therapeutische peptide.
GR900100613A (el)	1991-12-30	Θεραπευτικά πεπτίδια.
ES2062514T5 (es)	1998-06-01	Sistema de procesamiento de levadura que comprende un aminoacido cargado negativamente adyacente al sitio de procesamiento.
DK0464140T3 (da)	1994-09-05	Aktivt adhæsionspeptid
ATE182901T1 (de)	1999-08-15	Für androgen-rezeptor-protein kodierende dna
ES2194017T3 (es)	2003-11-16	Proceso para producir polipeptidos, proteinas o peptidos hidrofobos.
BR8907452A (pt)	1991-04-02	Peptideo e polipeptideo antifilicos,processo e composicao para sua utilizacao
ES2094725T3 (es)	1997-02-01	Peptidos hcg para la aplicacion en procedimientos de purificacion de anticuerpos.
PT95057A (pt)	1991-05-22	Processo para a preparacao de peptidos terapeuticos
ATE129744T1 (de)	1995-11-15	Rekombinantes c-terminal alpha amidatierungsenzym von menschlischem thyroidursprung.
PT93320A (pt)	1991-10-15	Processo para a preparacao de peptideos terapeuticos
ATE46173T1 (de)	1989-09-15	Pharmakologisch aktive peptide.