PT954521E - Derivados do 4-¬(tien-3-il)metil|imidazole possuindo actividade agonista para o receptor alfa2-adrenergico - Google Patents

Derivados do 4-¬(tien-3-il)metil|imidazole possuindo actividade agonista para o receptor alfa2-adrenergico

Info

Publication number
PT954521E
PT954521E PT97919907T PT97919907T PT954521E PT 954521 E PT954521 E PT 954521E PT 97919907 T PT97919907 T PT 97919907T PT 97919907 T PT97919907 T PT 97919907T PT 954521 E PT954521 E PT 954521E
Authority
PT
Portugal
Prior art keywords
tien
alpha2
derivatives
adrenergic receptor
agonist activity
Prior art date
Application number
PT97919907T
Other languages
English (en)
Inventor
Chris Royce Rasmussen
Jeffrey B Press
Robert E Boyd
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of PT954521E publication Critical patent/PT954521E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT97919907T 1996-03-28 1997-03-26 Derivados do 4-¬(tien-3-il)metil|imidazole possuindo actividade agonista para o receptor alfa2-adrenergico PT954521E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/625,442 US5750720A (en) 1996-03-28 1996-03-28 4- (thien-3-yl)methyl!-imidazole analgesics

Publications (1)

Publication Number Publication Date
PT954521E true PT954521E (pt) 2003-09-30

Family

ID=24506097

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97919907T PT954521E (pt) 1996-03-28 1997-03-26 Derivados do 4-¬(tien-3-il)metil|imidazole possuindo actividade agonista para o receptor alfa2-adrenergico

Country Status (14)

Country Link
US (1) US5750720A (pt)
EP (1) EP0954521B1 (pt)
JP (1) JP2000507549A (pt)
AT (1) ATE240321T1 (pt)
AU (1) AU721867B2 (pt)
DE (1) DE69722031T2 (pt)
DK (1) DK0954521T3 (pt)
ES (1) ES2198567T3 (pt)
NO (1) NO984481L (pt)
NZ (1) NZ332012A (pt)
PT (1) PT954521E (pt)
TW (1) TW504512B (pt)
WO (1) WO1997035858A1 (pt)
ZA (1) ZA972778B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002254265B2 (en) * 1997-12-04 2008-05-15 Allergan, Inc. Imidiazole derivatives and their use as agonists selective at alpha 2B or 2B/2C adrenergic receptors
JP4783502B2 (ja) * 1997-12-04 2011-09-28 アラーガン、インコーポレイテッド α２Ｂまたは２Ｂ／２Ｃアドレナリン受容体において作動剤様活性を示す置換イミダゾール誘導体
US6841684B2 (en) * 1997-12-04 2005-01-11 Allergan, Inc. Imidiazoles having reduced side effects
US6329369B1 (en) 1997-12-04 2001-12-11 Allergan Sales, Inc. Methods of treating pain and other conditions
US6426356B1 (en) 1998-11-18 2002-07-30 Ortho-Mcneil Pharmaceutical, Inc. Imidazoethyl thiophenes
US6465486B1 (en) 1999-03-12 2002-10-15 Ortho-Mcneil Pharmaceutical, Inc. Pyridyl/quinolinyl imidazoles
TWI283669B (en) * 1999-06-10 2007-07-11 Allergan Inc Compounds and method of treatment having agonist-like activity selective at alpha 2B or 2B/2C adrenergic receptors
US7893191B2 (en) 2007-02-28 2011-02-22 Corning Incorporated Fused thiophenes, methods for making fused thiophenes, and uses thereof
KR101206202B1 (ko) 2004-09-14 2012-11-29 코닝 인코포레이티드 융합 티오펜, 융합 티오펜의 제조방법 및 그 용도
US7838623B2 (en) 2004-09-14 2010-11-23 Corning Incorporated Fused thiophenes, methods for making fused thiophenes, and uses thereof
CA2632565A1 (en) * 2005-12-19 2007-07-05 Syngenta Limited Substituted aromatic heterocyclic compounds as fungicides
ES2402746T3 (es) * 2007-05-14 2013-05-08 Allergan, Inc. Compuestos de (fenil)(imidazolil)metilheteroarilo
KR101652533B1 (ko) 2008-03-31 2016-08-30 코닝 인코포레이티드 융합 티오펜 화합물, 이들을 제조하는 방법 및 이들의 용도
EP2595985A1 (en) * 2010-07-19 2013-05-29 Syngenta Participations AG Isoxazole, isothiazole, furane and thiophene compounds as microbicides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01242571A (ja) * 1988-03-22 1989-09-27 Mitsui Petrochem Ind Ltd イミダゾール誘導体の製造方法
FI894911A0 (fi) * 1989-10-17 1989-10-17 Farmos Oy En terapeutiskt vaerdefull foerening.
JPH06507392A (ja) * 1991-02-26 1994-08-25 エイアールシー　１，インコーポレイテッド 交感神経性の持続性疼痛の治療のための組成物および方法
US5621113A (en) * 1996-03-28 1997-04-15 Ortho Pharmaceutical Corporation 4-[(thien-2-yl)methyl]-imidazole analgesics

Also Published As

Publication number Publication date
DE69722031D1 (en) 2003-06-18
US5750720A (en) 1998-05-12
EP0954521B1 (en) 2003-05-14
AU721867B2 (en) 2000-07-13
WO1997035858A1 (en) 1997-10-02
ES2198567T3 (es) 2004-02-01
DE69722031T2 (de) 2004-01-29
JP2000507549A (ja) 2000-06-20
NO984481L (no) 1998-11-23
NZ332012A (en) 2000-07-28
EP0954521A1 (en) 1999-11-10
ATE240321T1 (de) 2003-05-15
AU2422997A (en) 1997-10-17
ZA972778B (en) 1998-10-01
TW504512B (en) 2002-10-01
DK0954521T3 (da) 2003-09-15
NO984481D0 (no) 1998-09-25

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