PT97680A - Processo para preparacao de novos compostos sulfonilo e de composicoes farmaceuticas que os contem - Google Patents

Processo para preparacao de novos compostos sulfonilo e de composicoes farmaceuticas que os contem

Info

Publication number
PT97680A
PT97680A PT97680A PT9768091A PT97680A PT 97680 A PT97680 A PT 97680A PT 97680 A PT97680 A PT 97680A PT 9768091 A PT9768091 A PT 9768091A PT 97680 A PT97680 A PT 97680A
Authority
PT
Portugal
Prior art keywords
formula
pct
preparation
new compounds
date nov
Prior art date
Application number
PT97680A
Other languages
English (en)
Other versions
PT97680B (pt
Inventor
Kurt Klemm
Dieter Flockerzi
Hermann Amschler
Volker Figala
Rolf Beume
Dietrich Hafner
Guido Hanauer
Manfried Eltze
Christian Schudt
Ulrich Kilian
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of PT97680A publication Critical patent/PT97680A/pt
Publication of PT97680B publication Critical patent/PT97680B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heat Treatment Of Steel (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
PT97680A 1990-05-16 1991-05-15 Processo para preparacao de novos compostos sulfonilo e de composicoes farmaceuticas que os contem PT97680B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH165890 1990-05-16

Publications (2)

Publication Number Publication Date
PT97680A true PT97680A (pt) 1992-02-28
PT97680B PT97680B (pt) 1998-09-30

Family

ID=4215610

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97680A PT97680B (pt) 1990-05-16 1991-05-15 Processo para preparacao de novos compostos sulfonilo e de composicoes farmaceuticas que os contem

Country Status (23)

Country Link
US (1) US5346904A (pt)
EP (1) EP0528922B1 (pt)
JP (1) JP3238397B2 (pt)
CN (1) CN1027507C (pt)
AT (1) ATE181330T1 (pt)
AU (1) AU651592B2 (pt)
CA (1) CA2082923C (pt)
CS (1) CS144791A3 (pt)
DE (3) DE4191109A1 (pt)
DK (1) DK0528922T3 (pt)
ES (1) ES2134777T3 (pt)
FI (1) FI925005L (pt)
GR (1) GR3031098T3 (pt)
HU (2) HUT62895A (pt)
IE (1) IE911625A1 (pt)
IL (1) IL98133A (pt)
MY (1) MY105344A (pt)
NO (1) NO924414L (pt)
NZ (1) NZ238141A (pt)
PT (1) PT97680B (pt)
WO (1) WO1991017991A1 (pt)
YU (1) YU85691A (pt)
ZA (1) ZA913627B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993009780A1 (de) * 1991-11-15 1993-05-27 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung von sulfonylverbindungen
US5958926A (en) * 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
DK0937074T3 (da) * 1996-11-11 2003-06-23 Altana Pharma Ag Benzonaphthyridiner som bronkiale terapeutiske midler
SI0968211T1 (en) * 1997-03-07 2004-02-29 Altana Pharma Ag Tetrazole derivatives
AU8106598A (en) 1997-06-03 1998-12-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine
DE69828284T2 (de) 1997-06-30 2005-12-08 Nippon Kayaku K.K. Naphthyridinderivate oder salze davon
PL200923B1 (pl) 1999-08-21 2009-02-27 Nycomed Gmbh Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2627848T3 (es) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US8196556B2 (en) * 2009-09-17 2012-06-12 Delphi Technologies, Inc. Apparatus and method for setting mechanical lash in a valve-deactivating hydraulic lash adjuster
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
MX357121B (es) 2011-03-01 2018-06-27 Synergy Pharmaceuticals Inc Star Proceso de preparacion de agonistas c de guanilato ciclasa.
EP2958577A2 (en) 2013-02-25 2015-12-30 Synergy Pharmaceuticals Inc. Guanylate cyclase receptor agonists for use in colonic cleansing
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
CA2920856C (en) 2013-08-09 2026-03-03 Ardelyx, Inc. Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス， インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
US4087530A (en) * 1974-02-05 1978-05-02 Sandoz Ltd. Substituted 6-phenyl-octahydrobenzo [c] [1,6] naphthyridines
FI750205A7 (pt) * 1974-02-05 1975-08-06 Sandoz Ag
EP0247971A3 (en) * 1986-05-29 1990-01-17 Sandoz Ag Novel pharmaceutical compositions comprising and use of cis-6-(4-acetanilido)-8,9-dimethoxy-2-methyl-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridin

Also Published As

Publication number Publication date
NO924414D0 (no) 1992-11-16
DK0528922T3 (da) 1999-11-22
FI925005A7 (fi) 1992-11-05
FI925005A0 (fi) 1992-11-05
IE911625A1 (en) 1991-11-20
FI925005L (fi) 1992-11-05
CA2082923A1 (en) 1991-11-17
JP3238397B2 (ja) 2001-12-10
US5346904A (en) 1994-09-13
CN1056691A (zh) 1991-12-04
AU7870191A (en) 1991-12-10
CS144791A3 (en) 1992-03-18
ES2134777T3 (es) 1999-10-16
DE59109135D1 (de) 1999-07-22
CN1027507C (zh) 1995-01-25
ZA913627B (en) 1992-01-29
HUT62895A (en) 1993-06-28
EP0528922A1 (de) 1993-03-03
GR3031098T3 (en) 1999-12-31
NZ238141A (en) 1993-07-27
HU9203557D0 (en) 1993-03-29
CA2082923C (en) 2001-12-18
IL98133A (en) 1994-11-11
AU651592B2 (en) 1994-07-28
PT97680B (pt) 1998-09-30
ATE181330T1 (de) 1999-07-15
DE4191109D2 (en) 1993-04-01
MY105344A (en) 1994-09-30
DE4191109A1 (pt) 1993-04-01
NO924414L (no) 1992-11-16
IL98133A0 (en) 1992-06-21
EP0528922B1 (de) 1999-06-16
WO1991017991A1 (de) 1991-11-28
YU85691A (sh) 1994-06-24
JPH05507081A (ja) 1993-10-14

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Effective date: 20021217

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