ES2134777T3 - Nuevos compuestos de sulfonilo. - Google Patents

Nuevos compuestos de sulfonilo.

Info

Publication number
ES2134777T3
ES2134777T3 ES91909549T ES91909549T ES2134777T3 ES 2134777 T3 ES2134777 T3 ES 2134777T3 ES 91909549 T ES91909549 T ES 91909549T ES 91909549 T ES91909549 T ES 91909549T ES 2134777 T3 ES2134777 T3 ES 2134777T3
Authority
ES
Spain
Prior art keywords
new
sulphonyl compounds
compounds
new sulphonyl
substitutes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91909549T
Other languages
English (en)
Inventor
Dieter Flockerzi
Kurt Klemm
Hermann Amschler
Volker Figala
Rolf Beume
Dietrich Hafner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Application granted granted Critical
Publication of ES2134777T3 publication Critical patent/ES2134777T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heat Treatment Of Steel (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)

Abstract

COMPUESTOS DE LA FORMULA (I), EN LOS QUE LOS SUSTITUYENTES TIENEN EL SIGNIFICADO DADO EN LA DESCRIPCION, SON BRONCODILATADORES NUEVOS Y EFICACES.
ES91909549T 1990-05-16 1991-05-14 Nuevos compuestos de sulfonilo. Expired - Lifetime ES2134777T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH165890 1990-05-16

Publications (1)

Publication Number Publication Date
ES2134777T3 true ES2134777T3 (es) 1999-10-16

Family

ID=4215610

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91909549T Expired - Lifetime ES2134777T3 (es) 1990-05-16 1991-05-14 Nuevos compuestos de sulfonilo.

Country Status (23)

Country Link
US (1) US5346904A (es)
EP (1) EP0528922B1 (es)
JP (1) JP3238397B2 (es)
CN (1) CN1027507C (es)
AT (1) ATE181330T1 (es)
AU (1) AU651592B2 (es)
CA (1) CA2082923C (es)
CS (1) CS144791A3 (es)
DE (3) DE4191109A1 (es)
DK (1) DK0528922T3 (es)
ES (1) ES2134777T3 (es)
FI (1) FI925005L (es)
GR (1) GR3031098T3 (es)
HU (2) HUT62895A (es)
IE (1) IE911625A1 (es)
IL (1) IL98133A (es)
MY (1) MY105344A (es)
NO (1) NO924414L (es)
NZ (1) NZ238141A (es)
PT (1) PT97680B (es)
WO (1) WO1991017991A1 (es)
YU (1) YU85691A (es)
ZA (1) ZA913627B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993009780A1 (de) * 1991-11-15 1993-05-27 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung von sulfonylverbindungen
US5958926A (en) * 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
DK0937074T3 (da) * 1996-11-11 2003-06-23 Altana Pharma Ag Benzonaphthyridiner som bronkiale terapeutiske midler
SI0968211T1 (en) * 1997-03-07 2004-02-29 Altana Pharma Ag Tetrazole derivatives
AU8106598A (en) 1997-06-03 1998-12-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine
DE69828284T2 (de) 1997-06-30 2005-12-08 Nippon Kayaku K.K. Naphthyridinderivate oder salze davon
PL200923B1 (pl) 1999-08-21 2009-02-27 Nycomed Gmbh Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2627848T3 (es) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US8196556B2 (en) * 2009-09-17 2012-06-12 Delphi Technologies, Inc. Apparatus and method for setting mechanical lash in a valve-deactivating hydraulic lash adjuster
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
MX357121B (es) 2011-03-01 2018-06-27 Synergy Pharmaceuticals Inc Star Proceso de preparacion de agonistas c de guanilato ciclasa.
EP2958577A2 (en) 2013-02-25 2015-12-30 Synergy Pharmaceuticals Inc. Guanylate cyclase receptor agonists for use in colonic cleansing
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
CA2920856C (en) 2013-08-09 2026-03-03 Ardelyx, Inc. Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス， インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
US4087530A (en) * 1974-02-05 1978-05-02 Sandoz Ltd. Substituted 6-phenyl-octahydrobenzo [c] [1,6] naphthyridines
FI750205A7 (es) * 1974-02-05 1975-08-06 Sandoz Ag
EP0247971A3 (en) * 1986-05-29 1990-01-17 Sandoz Ag Novel pharmaceutical compositions comprising and use of cis-6-(4-acetanilido)-8,9-dimethoxy-2-methyl-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridin

Also Published As

Publication number Publication date
NO924414D0 (no) 1992-11-16
DK0528922T3 (da) 1999-11-22
FI925005A7 (fi) 1992-11-05
FI925005A0 (fi) 1992-11-05
IE911625A1 (en) 1991-11-20
FI925005L (fi) 1992-11-05
CA2082923A1 (en) 1991-11-17
JP3238397B2 (ja) 2001-12-10
US5346904A (en) 1994-09-13
CN1056691A (zh) 1991-12-04
AU7870191A (en) 1991-12-10
CS144791A3 (en) 1992-03-18
DE59109135D1 (de) 1999-07-22
CN1027507C (zh) 1995-01-25
ZA913627B (en) 1992-01-29
HUT62895A (en) 1993-06-28
PT97680A (pt) 1992-02-28
EP0528922A1 (de) 1993-03-03
GR3031098T3 (en) 1999-12-31
NZ238141A (en) 1993-07-27
HU9203557D0 (en) 1993-03-29
CA2082923C (en) 2001-12-18
IL98133A (en) 1994-11-11
AU651592B2 (en) 1994-07-28
PT97680B (pt) 1998-09-30
ATE181330T1 (de) 1999-07-15
DE4191109D2 (en) 1993-04-01
MY105344A (en) 1994-09-30
DE4191109A1 (es) 1993-04-01
NO924414L (no) 1992-11-16
IL98133A0 (en) 1992-06-21
EP0528922B1 (de) 1999-06-16
WO1991017991A1 (de) 1991-11-28
YU85691A (sh) 1994-06-24
JPH05507081A (ja) 1993-10-14

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