RO80864A - Procede d'obtention d'un copolymere en base d'acide lactique et acideglycolique - Google Patents

Procede d'obtention d'un copolymere en base d'acide lactique et acideglycolique

Info

Publication number
RO80864A
RO80864A RO80102132A RO10213280A RO80864A RO 80864 A RO80864 A RO 80864A RO 80102132 A RO80102132 A RO 80102132A RO 10213280 A RO10213280 A RO 10213280A RO 80864 A RO80864 A RO 80864A
Authority
RO
Romania
Prior art keywords
glycolic
acid
copolimer
obtaining
lactic acid
Prior art date
Application number
RO80102132A
Other languages
English (en)
Romanian (ro)
Inventor
Robert S Nevin
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of RO80864A publication Critical patent/RO80864A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C08G63/823—Preparation processes characterised by the catalyst used for the preparation of polylactones or polylactides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Biological Depolymerization Polymers (AREA)
RO80102132A 1979-09-12 1980-09-09 Procede d'obtention d'un copolymere en base d'acide lactique et acideglycolique RO80864A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/075,296 US4273920A (en) 1979-09-12 1979-09-12 Polymerization process and product

Publications (1)

Publication Number Publication Date
RO80864A true RO80864A (fr) 1983-02-01

Family

ID=22124778

Family Applications (1)

Application Number Title Priority Date Filing Date
RO80102132A RO80864A (fr) 1979-09-12 1980-09-09 Procede d'obtention d'un copolymere en base d'acide lactique et acideglycolique

Country Status (31)

Country Link
US (1) US4273920A (fr)
EP (1) EP0026599B1 (fr)
JP (2) JPS5645920A (fr)
AR (1) AR221173A1 (fr)
AT (1) AT380689B (fr)
AU (1) AU539130B2 (fr)
BE (1) BE885182A (fr)
BG (1) BG41132A3 (fr)
CA (1) CA1185048A (fr)
CH (1) CH648048A5 (fr)
CS (1) CS221979B2 (fr)
DD (1) DD153125A5 (fr)
DE (1) DE3068116D1 (fr)
DK (1) DK155093C (fr)
EG (1) EG14381A (fr)
ES (1) ES8106542A1 (fr)
FI (1) FI66412C (fr)
FR (1) FR2464973A1 (fr)
GB (1) GB2058808B (fr)
GR (1) GR69961B (fr)
GT (1) GT198065361A (fr)
HU (1) HU191807B (fr)
IE (1) IE50236B1 (fr)
IL (1) IL61024A (fr)
IT (1) IT1141040B (fr)
NZ (1) NZ194902A (fr)
PH (1) PH15272A (fr)
PL (1) PL129779B1 (fr)
PT (1) PT71794B (fr)
RO (1) RO80864A (fr)
ZA (1) ZA805629B (fr)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
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US4716964A (en) * 1981-08-10 1988-01-05 Exxon Production Research Company Use of degradable ball sealers to seal casing perforations in well treatment fluid diversion
US4523591A (en) * 1982-10-22 1985-06-18 Kaplan Donald S Polymers for injection molding of absorbable surgical devices
FR2537980B1 (fr) * 1982-12-17 1986-12-19 Sandoz Sa Derives d'acides hydroxycarboxyliques oligomeres, leur preparation et leur utilisation
US4470416A (en) * 1983-06-17 1984-09-11 Ethicon, Inc. Copolymers of lactide and/or glycolide with 1,5-dioxepan-2-one
CH656884A5 (de) * 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
US4594407A (en) * 1983-09-20 1986-06-10 Allied Corporation Prosthetic devices derived from krebs-cycle dicarboxylic acids and diols
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
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US4649042A (en) * 1984-05-31 1987-03-10 Eli Lilly And Company Rumen delivery device
JPH0678425B2 (ja) * 1984-07-06 1994-10-05 和光純薬工業株式会社 重合体の新規製造法
CA1256638A (fr) * 1984-07-06 1989-06-27 Motoaki Tanaka Polymere, et sa production
DE3428640A1 (de) * 1984-08-03 1986-02-06 Akzo Gmbh, 5600 Wuppertal Mikroporoese, pulverfoermige polylactide
US4595713A (en) * 1985-01-22 1986-06-17 Hexcel Corporation Medical putty for tissue augmentation
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JP2551756B2 (ja) * 1985-05-07 1996-11-06 武田薬品工業株式会社 ポリオキシカルボン酸エステルおよびその製造法
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JPH0610252B2 (ja) * 1985-08-21 1994-02-09 和光純薬工業株式会社 重合体の製造法
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OA09249A (fr) * 1988-12-19 1992-06-30 Lilly Co Eli Composés de macrolides.
JP2986509B2 (ja) * 1989-05-26 1999-12-06 三井化学株式会社 変性ポリエステル樹脂組成物、その製造方法、およびその用途
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US5302694A (en) * 1990-02-21 1994-04-12 Boehringer Ingelheim Gmbh Process for preparing polyesters based on hydroxycarboxylic acids
DE69129770T2 (de) * 1990-04-13 1998-11-19 Takeda Chemical Industries Ltd Biologisch abbaubare hochmolekulare Polymere, ihre Herstellung und ihre Verwendung
MY108621A (en) * 1990-08-01 1996-10-31 Novartis Ag Polylactide preparation and purification
US6353030B1 (en) * 1990-08-01 2002-03-05 Novartis Ag Relating to organic compounds
US5108422A (en) * 1990-10-22 1992-04-28 United States Surgical Corporation Skin fastener
US5593423A (en) * 1990-10-22 1997-01-14 United States Surgical Corporation Skin fastener
US5320624A (en) * 1991-02-12 1994-06-14 United States Surgical Corporation Blends of glycolide and/or lactide polymers and caprolactone and/or trimethylene carbonate polymers and absorbable surgical devices made therefrom
US6228954B1 (en) 1991-02-12 2001-05-08 United States Surgical Corporation Blends of glycolide and/or lactide polymers and caprolactone and/or trimethylene carbonate polymers and absorabable surgical devices made therefrom
IT1249045B (it) * 1991-02-21 1995-02-11 Himont Inc Processo per la sintesi allo stato solido di polimeri dell'acido lattico e prodotti cosi ottenuti
US5232648A (en) * 1991-07-19 1993-08-03 United States Surgical Corporation Bioabsorbable melt spun fiber based on glycolide-containing copolymer
US5206341A (en) * 1991-11-21 1993-04-27 Southern Research Institute Polymers from hydroxy acids and polycarboxylic acids
ES2139646T3 (es) * 1991-12-19 2000-02-16 Mitsui Chemicals Inc Acido polihidroxido carboxilico y su procedimiento de obtencion.
US5258488A (en) * 1992-01-24 1993-11-02 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US6326458B1 (en) 1992-01-24 2001-12-04 Cargill, Inc. Continuous process for the manufacture of lactide and lactide polymers
US6005067A (en) * 1992-01-24 1999-12-21 Cargill Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5247059A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for the manufacture of a purified lactide from esters of lactic acid
US5247058A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5142023A (en) * 1992-01-24 1992-08-25 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5338822A (en) * 1992-10-02 1994-08-16 Cargill, Incorporated Melt-stable lactide polymer composition and process for manufacture thereof
DE69330046T2 (de) * 1992-10-02 2001-11-15 Cargill, Inc. Schmelzstabiles lactidpolymergewebe und verfahren zu seiner herstellung
NZ256978A (en) * 1992-10-02 1996-05-28 Cargill Inc Paper product coated with a poly(lactide) composition comprising no more than 5 wt % lactide monomer, the poly(lactide) having a number average mw of 10,000 to 200,000
US6005068A (en) 1992-10-02 1999-12-21 Cargill Incorporated Melt-stable amorphous lactide polymer film and process for manufacture thereof
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
TW333456B (en) * 1992-12-07 1998-06-11 Takeda Pharm Ind Co Ltd A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
US5444143A (en) * 1992-12-25 1995-08-22 Mitsui Toatsu Chemicals, Inc. Preparation process of polyhydroxycarboxylic acid
WO1994020518A1 (fr) * 1993-03-12 1994-09-15 Dowelanco Nouveaux composes a83543 et procede de production desdits composes
KR970002523B1 (en) * 1993-04-24 1997-03-05 Korea Inst Sci & Tech Biodegradable polylactic acid having improved properties and method for manufacturing the same
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US5403347A (en) * 1993-05-27 1995-04-04 United States Surgical Corporation Absorbable block copolymers and surgical articles fabricated therefrom
WO1995010577A1 (fr) 1993-10-15 1995-04-20 H.B. Fuller Licensing & Financing Inc. Adhesifs thermofusibles biodegradables/recyclables en compost constitues de polyester d'acide lactique
US5431679A (en) * 1994-03-10 1995-07-11 United States Surgical Corporation Absorbable block copolymers and surgical articles fabricated therefrom
US5543202A (en) * 1994-03-14 1996-08-06 Kimberly-Clark Corporation Process for producing a crimp-bonded fibrous cellulosic laminate
CN1058736C (zh) * 1994-05-27 2000-11-22 北京市星辰现代控制工程研究所 生物降解组合物及其制备方法和应用
US5578662A (en) 1994-07-22 1996-11-26 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US6339130B1 (en) * 1994-07-22 2002-01-15 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US6206908B1 (en) 1994-09-16 2001-03-27 United States Surgical Corporation Absorbable polymer and surgical articles fabricated therefrom
CA2158420C (fr) 1994-09-16 2007-05-01 Mark S. Roby Polymeres absorbables et articles chirurgicaux fabriques a partir de ceux-ci
US5618313A (en) * 1994-10-11 1997-04-08 United States Surgical Corporation Absorbable polymer and surgical articles fabricated therefrom
US5770683A (en) 1994-11-02 1998-06-23 Mitsui Toatsu Chemicals, Inc. Preparation process of polyhydroxycarboxylic acid
US5997568A (en) * 1996-01-19 1999-12-07 United States Surgical Corporation Absorbable polymer blends and surgical articles fabricated therefrom
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
US5756651A (en) * 1996-07-17 1998-05-26 Chronopol, Inc. Impact modified polylactide
US6191236B1 (en) 1996-10-11 2001-02-20 United States Surgical Corporation Bioabsorbable suture and method of its manufacture
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CN1269870C (zh) * 2000-08-07 2006-08-16 和光纯药工业株式会社 乳酸聚合物及其制备方法
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TWI332407B (en) * 2001-06-29 2010-11-01 Takeda Chemical Industries Ltd Controlled release composition and method of producting the same
JP4612239B2 (ja) * 2001-07-18 2011-01-12 三井化学株式会社 生体吸収性ポリヒドロキシカルボン酸の製造方法
US7163545B2 (en) * 2002-07-29 2007-01-16 Mayo Foundation For Medical Education And Research Spinal cord surgical implant
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FR2867698B1 (fr) * 2004-03-16 2007-11-16 Beaufour Ipsen S C R A S Systeme catalttique de (co) oligomerisation du lactide et du glycolide
WO2005105908A1 (fr) * 2004-04-28 2005-11-10 Keio University Procédé de dépolymérisation de polymère ayant un lien d'ester dans la chaine principale et procédé pour produire le polymere ayant le lien d'ester dans la chaine princpale depuis le produit de dépolymérisation
MX2009006653A (es) 2006-12-18 2009-07-02 Takeda Pharmaceutical Composicion de liberacion prolongada y metodo para producirla.
CN101284883B (zh) * 2008-05-14 2011-02-16 西北大学 聚乳酸-壳聚糖接枝共聚物的制备方法
RU2404198C2 (ru) * 2008-11-12 2010-11-20 Федеральное государственное унитарное предприятие "Ордена Трудового Красного Знамени Научно-исследовательский физико-химический институт имени Л.Я. Карпова" Способ получения сополимеров стирола с молочной кислотой
CN103300120B (zh) * 2013-06-25 2015-04-22 南京工业大学 一种绿色家禽家畜脱毛剂及其制备方法
IL272809B2 (en) 2017-08-31 2025-05-01 Evonik Corp Improved resorbable polymer purification process

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US2362511A (en) * 1939-11-21 1944-11-14 Du Pont Modified glycolide resins
US2703316A (en) * 1951-06-05 1955-03-01 Du Pont Polymers of high melting lactide
US2758987A (en) * 1952-06-05 1956-08-14 Du Pont Optically active homopolymers containing but one antipodal species of an alpha-monohydroxy monocarboxylic acid
US3268487A (en) * 1963-12-23 1966-08-23 Shell Oil Co Process for polymerization of lactides
US3535419A (en) * 1965-12-15 1970-10-20 Syntex Corp Veterinary compositions and methods
US3442871A (en) * 1966-05-04 1969-05-06 American Cyanamid Co Process for polymerizing a glycolide
US3458622A (en) * 1967-04-07 1969-07-29 Squibb & Sons Inc Controlled release tablet
US3887699A (en) * 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
BE758156R (fr) * 1970-05-13 1971-04-28 Ethicon Inc Element de suture absorbable et sa
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US3839297A (en) * 1971-11-22 1974-10-01 Ethicon Inc Use of stannous octoate catalyst in the manufacture of l(-)lactide-glycolide copolymer sutures
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Also Published As

Publication number Publication date
AR221173A1 (es) 1980-12-30
GT198065361A (es) 1982-03-04
FI802840A7 (fi) 1981-03-13
PT71794A (en) 1980-10-01
AU6216680A (en) 1981-03-19
NZ194902A (en) 1983-05-31
DK155093C (da) 1989-06-19
HU191807B (en) 1987-04-28
IE801902L (en) 1981-03-12
IE50236B1 (en) 1986-03-05
ES494974A0 (es) 1981-08-16
EP0026599A1 (fr) 1981-04-08
ES8106542A1 (es) 1981-08-16
CS221979B2 (en) 1983-04-29
JPH0198617A (ja) 1989-04-17
DK155093B (da) 1989-02-06
FR2464973A1 (fr) 1981-03-20
DE3068116D1 (en) 1984-07-12
IL61024A0 (en) 1980-11-30
IT8024607A0 (it) 1980-09-11
JPS5645920A (en) 1981-04-25
GB2058808B (en) 1983-11-16
JPH0445525B2 (fr) 1992-07-27
AU539130B2 (en) 1984-09-13
PL129779B1 (en) 1984-06-30
FR2464973B1 (fr) 1983-06-10
IT1141040B (it) 1986-10-01
CH648048A5 (fr) 1985-02-28
EP0026599B1 (fr) 1984-06-06
EG14381A (en) 1983-12-31
GB2058808A (en) 1981-04-15
DK387380A (da) 1981-03-13
DD153125A5 (de) 1981-12-23
FI66412B (fi) 1984-06-29
BE885182A (fr) 1981-03-11
AT380689B (de) 1986-06-25
FI66412C (fi) 1984-10-10
GR69961B (fr) 1982-07-22
ZA805629B (en) 1982-04-28
PL226653A1 (fr) 1981-10-16
JPH0121166B2 (fr) 1989-04-20
IL61024A (en) 1983-02-23
US4273920A (en) 1981-06-16
PT71794B (en) 1981-07-07
ATA455380A (de) 1985-11-15
BG41132A3 (bg) 1987-04-15
CA1185048A (fr) 1985-04-02
PH15272A (en) 1982-11-02

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