SK281282B6 - 7-(2-aminoetyl)benzotiazolóny, spôsob ich výroby, farmaceutická kompozícia s ich obsahom a medziprodukt spôsobu výroby - Google Patents

7-(2-aminoetyl)benzotiazolóny, spôsob ich výroby, farmaceutická kompozícia s ich obsahom a medziprodukt spôsobu výroby Download PDF

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Publication number
SK281282B6
SK281282B6 SK1433-94A SK143394A SK281282B6 SK 281282 B6 SK281282 B6 SK 281282B6 SK 143394 A SK143394 A SK 143394A SK 281282 B6 SK281282 B6 SK 281282B6
Authority
SK
Slovakia
Prior art keywords
formula
hydroxy
ethyl
benzothiazol
aminoethyl
Prior art date
Application number
SK1433-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK143394A3 (en
Inventor
Roger Victor Bonnert
Roger Charles Brown
David Ranulf Cheshire
Francis Ince
Original Assignee
Astra Pharmaceuticals Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharmaceuticals Limited filed Critical Astra Pharmaceuticals Limited
Publication of SK143394A3 publication Critical patent/SK143394A3/sk
Publication of SK281282B6 publication Critical patent/SK281282B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Cosmetics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Adhesives Or Adhesive Processes (AREA)
SK1433-94A 1992-05-27 1993-05-27 7-(2-aminoetyl)benzotiazolóny, spôsob ich výroby, farmaceutická kompozícia s ich obsahom a medziprodukt spôsobu výroby SK281282B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929211172A GB9211172D0 (en) 1992-05-27 1992-05-27 Compounds
PCT/GB1993/001095 WO1993024473A1 (en) 1992-05-27 1993-05-27 7-(2-aminoethyl)-benzothiazolones

Publications (2)

Publication Number Publication Date
SK143394A3 SK143394A3 (en) 1995-06-07
SK281282B6 true SK281282B6 (sk) 2001-02-12

Family

ID=10716059

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1433-94A SK281282B6 (sk) 1992-05-27 1993-05-27 7-(2-aminoetyl)benzotiazolóny, spôsob ich výroby, farmaceutická kompozícia s ich obsahom a medziprodukt spôsobu výroby

Country Status (31)

Country Link
EP (1) EP0649418B1 (de)
JP (1) JP3094452B2 (de)
KR (1) KR100279132B1 (de)
CN (1) CN1036393C (de)
AT (1) ATE172726T1 (de)
AU (1) AU675649B2 (de)
CA (1) CA2136553C (de)
CZ (1) CZ286905B6 (de)
DE (1) DE69321835T2 (de)
DK (1) DK0649418T3 (de)
DZ (1) DZ1694A1 (de)
ES (1) ES2123652T3 (de)
FI (1) FI945538A0 (de)
GB (1) GB9211172D0 (de)
HU (2) HUT71124A (de)
IL (1) IL105801A (de)
LV (1) LV12443B (de)
MA (1) MA22895A1 (de)
MX (1) MX9303145A (de)
MY (1) MY131193A (de)
NO (1) NO304739B1 (de)
NZ (1) NZ253190A (de)
PH (1) PH31453A (de)
PL (2) PL172807B1 (de)
RU (1) RU2114108C1 (de)
SG (1) SG48068A1 (de)
SK (1) SK281282B6 (de)
TW (1) TW368501B (de)
UA (1) UA27901C2 (de)
WO (1) WO1993024473A1 (de)
ZA (1) ZA933648B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW356468B (en) * 1995-09-15 1999-04-21 Astra Pharma Prod Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
GB9526511D0 (en) * 1995-12-23 1996-02-28 Astra Pharma Prod Pharmaceutically active compounds
SE9900693D0 (sv) * 1999-02-26 1999-02-26 Astra Pharma Prod Novel process
SE9902938D0 (sv) * 1999-08-18 1999-08-18 Astra Pharma Prod Pharmaceutical compositions
SE9902937D0 (sv) * 1999-08-18 1999-08-18 Astra Pharma Prod Pharmaceutical compositions
SE9902935D0 (sv) * 1999-08-18 1999-08-18 Astra Pharma Prod Pharmaceutical compositions
SE9902936D0 (sv) * 1999-08-18 1999-08-18 Astra Pharma Prod Pharmaceutical compositions
DE10063957A1 (de) * 2000-12-20 2002-06-27 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Dopamin-Agonisten
GB0218629D0 (en) * 2002-08-09 2002-09-18 Novartis Ag Organic compounds
PE20050130A1 (es) * 2002-08-09 2005-03-29 Novartis Ag Compuestos organicos
ES2329586T3 (es) 2003-11-21 2009-11-27 Theravance, Inc. Compuestos que tienen actividad agonista del receptor beta2 adrenergico y antagonista del receptor muscarino.
RU2281769C2 (ru) * 2004-07-16 2006-08-20 Федеральное государственное научное учреждение Всероссийский научно-исследовательский ветеринарный институт Средство для лечения дерматомикозов
GB0426164D0 (en) * 2004-11-29 2004-12-29 Novartis Ag Organic compounds
RU2288715C2 (ru) * 2005-01-11 2006-12-10 ГОУ ВПО "Воронежская государственная медицинская академия им. Н.Н. Бурденко Министерства здравоохранения Российской Федерации" Способ лечения бронхиальной астмы
TW200738658A (en) 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
RU2415136C2 (ru) * 2005-08-09 2011-03-27 Астразенека Аб Новые производные бензотиазолона
TW200738659A (en) * 2005-08-29 2007-10-16 Astrazeneca Ab Novel compounds
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
RU2455295C2 (ru) * 2006-12-20 2012-07-10 АстраЗенека AБ 4-ГИДРОКСИ-2-ОКСО-2,3-ДИГИДРО-1,3-БЕНЗОТИАЗОЛ-7-ИЛЬНЫЕ СОЕДИНЕНИЯ ДЛЯ МОДУЛЯЦИИ β2-АДРЕНОРЕЦЕПТОРНОЙ АКТИВНОСТИ
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
GB0704000D0 (en) * 2007-03-01 2007-04-11 Astrazeneca Ab Salts 670
WO2009154557A1 (en) 2008-06-18 2009-12-23 Astrazeneca Ab Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders
CN102977050B (zh) * 2012-11-20 2015-04-22 浙江工业大学 一种2-苯并噻唑二甲缩醛和2-苯并噻唑甲醛的合成方法
CN106748930B (zh) * 2016-12-05 2019-03-15 三门峡奥科化工有限公司 3-巯基-1-丙醇的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554284A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines

Also Published As

Publication number Publication date
DE69321835D1 (de) 1998-12-03
CN1085899A (zh) 1994-04-27
ATE172726T1 (de) 1998-11-15
DZ1694A1 (fr) 2002-02-17
EP0649418B1 (de) 1998-10-28
ES2123652T3 (es) 1999-01-16
JPH08503923A (ja) 1996-04-30
SG48068A1 (en) 1998-04-17
FI945538L (fi) 1994-11-25
MX9303145A (es) 1994-06-30
HUT71124A (en) 1995-11-28
NZ253190A (en) 1995-12-21
IL105801A0 (en) 1993-09-22
MY131193A (en) 2007-07-31
DK0649418T3 (da) 1999-07-12
AU675649B2 (en) 1997-02-13
CZ291694A3 (en) 1995-03-15
ZA933648B (en) 1993-11-25
SK143394A3 (en) 1995-06-07
NO944509D0 (no) 1994-11-24
GB9211172D0 (en) 1992-07-08
CN1036393C (zh) 1997-11-12
DE69321835T2 (de) 1999-05-12
LV12443A (en) 2000-03-20
TW368501B (en) 1999-09-01
HU9403387D0 (en) 1995-02-28
UA27901C2 (uk) 2000-10-16
LV12443B (en) 2000-06-20
CZ286905B6 (en) 2000-08-16
FI945538A7 (fi) 1994-11-25
PL172904B1 (pl) 1997-12-31
WO1993024473A1 (en) 1993-12-09
MA22895A1 (fr) 1993-12-31
KR100279132B1 (ko) 2001-01-15
AU4334393A (en) 1993-12-30
PH31453A (en) 1998-11-03
EP0649418A1 (de) 1995-04-26
NO944509L (no) 1994-11-24
PL172807B1 (pl) 1997-11-28
CA2136553A1 (en) 1993-12-09
HU211947A9 (en) 1996-01-29
RU2114108C1 (ru) 1998-06-27
JP3094452B2 (ja) 2000-10-03
CA2136553C (en) 2000-08-15
RU94046093A (ru) 1996-09-27
IL105801A (en) 1997-01-10
FI945538A0 (fi) 1994-11-25
NO304739B1 (no) 1999-02-08

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