SK282995B6 - Zlúčenina na inhibíciu metaloproteázy a prostriedok s jej obsahom - Google Patents

Zlúčenina na inhibíciu metaloproteázy a prostriedok s jej obsahom Download PDF

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Publication number
SK282995B6
SK282995B6 SK984-98A SK98498A SK282995B6 SK 282995 B6 SK282995 B6 SK 282995B6 SK 98498 A SK98498 A SK 98498A SK 282995 B6 SK282995 B6 SK 282995B6
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Slovakia
Prior art keywords
optionally substituted
compound
methyl
reaction
hydrate
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SK984-98A
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English (en)
Slovak (sk)
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SK98498A3 (en
Inventor
Fumihiko Watanabe
Hiroshige Tsuzuki
Mitsuaki Ohtani
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Shionogi And Co., Ltd.
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Application filed by Shionogi And Co., Ltd. filed Critical Shionogi And Co., Ltd.
Publication of SK98498A3 publication Critical patent/SK98498A3/sk
Publication of SK282995B6 publication Critical patent/SK282995B6/sk

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/42—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
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    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
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EP0950656A1 (en) 1999-10-20
AU1319597A (en) 1997-08-20
TW200403216A (en) 2004-03-01
RU2198656C2 (ru) 2003-02-20
CN100413859C (zh) 2008-08-27
KR19990081866A (ko) 1999-11-15
NO983376L (no) 1998-09-14
TR199801419T2 (xx) 1998-10-21
CZ298814B6 (cs) 2008-02-13
NO312665B1 (no) 2002-06-17
CZ225298A3 (cs) 1998-12-16
TW200407287A (en) 2004-05-16
DE69737605D1 (de) 2007-05-24
US6207698B1 (en) 2001-03-27
ATE359264T1 (de) 2007-05-15
TW575547B (en) 2004-02-11
US20030139379A1 (en) 2003-07-24
US6441021B1 (en) 2002-08-27
EP1486207A2 (en) 2004-12-15
SK98498A3 (en) 1999-04-13
HU226006B1 (en) 2008-02-28
CN1214041A (zh) 1999-04-14
BR9707010A (pt) 1999-07-20
US6235768B1 (en) 2001-05-22
NO983376D0 (no) 1998-07-22
US6881727B2 (en) 2005-04-19
WO1997027174A1 (en) 1997-07-31
NZ325939A (en) 2000-06-23
TWI244475B (en) 2005-12-01
EP1486207A3 (en) 2011-01-05
KR100338861B1 (ko) 2003-02-20
HUP9903687A2 (hu) 2000-03-28
TWI244474B (en) 2005-12-01
AU715764B2 (en) 2000-02-10
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IL125378A0 (en) 1999-03-12
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KR100338857B1 (ko) 2002-05-30
PL205341B1 (pl) 2010-04-30
PL198905B1 (pl) 2008-07-31
JP3628335B2 (ja) 2005-03-09
EP0950656B1 (en) 2007-04-11
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BR9707010B1 (pt) 2009-05-05
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