SU420170A3 - - Google Patents

Info

Publication number: SU420170A3
Authority: SU; USSR - Soviet Union
Prior art keywords: solution; mixture; acetic acid; chloroform; solvent
Prior art date: 1970-08-28

Application number

SU1691523A

Other languages

English (en)

Russian (ru)

Inventor

Герд Крюгер Клаус Рейнхольд Иолл Йохантес Кекк изобретени Хельмут Пнпер

Кэлинг ФРГ Иоахим

Original Assignee

Иностранна фирма

Карл Тотиэ Гмбх

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-08-28

Filing date

1970-09-29

Publication date

1974-03-15

1970-09-29 Application filed by Иностранна фирма, Карл Тотиэ Гмбх filed Critical Иностранна фирма

1974-03-15 Application granted granted Critical

1974-03-15 Publication of SU420170A3 publication Critical patent/SU420170A3/ru

Links

QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 37
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 21
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 16
239000000203 mixture Substances 0.000 description 15
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 10
239000002904 solvent Substances 0.000 description 10
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 7
229910052801 chlorine Inorganic materials 0.000 description 7
239000000460 chlorine Substances 0.000 description 7
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 6
PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 6
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 6
229910052794 bromium Inorganic materials 0.000 description 6
229910052938 sodium sulfate Inorganic materials 0.000 description 6
235000011152 sodium sulphate Nutrition 0.000 description 6
239000002026 chloroform extract Substances 0.000 description 5
239000003208 petroleum Substances 0.000 description 5
238000003756 stirring Methods 0.000 description 5
239000000126 substance Substances 0.000 description 4
MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 3
-1 benzyl snort Chemical compound 0.000 description 3
238000000354 decomposition reaction Methods 0.000 description 3
WVDDGKGOMKODPV-UHFFFAOYSA-N hydroxymethyl benzene Natural products OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 3
238000000034 method Methods 0.000 description 3
239000000047 product Substances 0.000 description 3
150000003839 salts Chemical class 0.000 description 3
239000000741 silica gel Substances 0.000 description 3
229910002027 silica gel Inorganic materials 0.000 description 3
235000011121 sodium hydroxide Nutrition 0.000 description 3
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical group CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 description 2
239000003518 caustics Substances 0.000 description 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 2
RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Natural products C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 description 2
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
241000167854 Bourreria succulenta Species 0.000 description 1
BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 description 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
101000881131 Homo sapiens RNA/RNP complex-1-interacting phosphatase Proteins 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
102100037566 RNA/RNP complex-1-interacting phosphatase Human genes 0.000 description 1
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 1
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 description 1
125000003545 alkoxy group Chemical group 0.000 description 1
125000005119 alkyl cycloalkyl group Chemical group 0.000 description 1
125000000217 alkyl group Chemical group 0.000 description 1
125000004414 alkyl thio group Chemical group 0.000 description 1
PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
235000019445 benzyl alcohol Nutrition 0.000 description 1
125000001246 bromo group Chemical group Br* 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
239000007795 chemical reaction product Substances 0.000 description 1
235000019693 cherries Nutrition 0.000 description 1
238000004587 chromatography analysis Methods 0.000 description 1
125000000753 cycloalkyl group Chemical group 0.000 description 1
125000004985 dialkyl amino alkyl group Chemical group 0.000 description 1
150000002168 ethanoic acid esters Chemical class 0.000 description 1
235000019439 ethyl acetate Nutrition 0.000 description 1
229910052731 fluorine Inorganic materials 0.000 description 1
239000011737 fluorine Substances 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
125000002768 hydroxyalkyl group Chemical group 0.000 description 1
239000000155 melt Substances 0.000 description 1
150000007522 mineralic acids Chemical class 0.000 description 1
125000001624 naphthyl group Chemical group 0.000 description 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
125000002868 norbornyl group Chemical group C12(CCC(CC1)C2)* 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
235000005985 organic acids Nutrition 0.000 description 1
235000006408 oxalic acid Nutrition 0.000 description 1
NIXKBAZVOQAHGC-UHFFFAOYSA-N phenylmethanesulfonic acid Chemical compound OS(=O)(=O)CC1=CC=CC=C1 NIXKBAZVOQAHGC-UHFFFAOYSA-N 0.000 description 1
239000002243 precursor Substances 0.000 description 1
125000004076 pyridyl group Chemical group 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000002002 slurry Substances 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

SU1691523A 1970-08-28 1970-09-29 SU420170A3 (2)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19702042750 DE2042750A1 (de)	1970-08-28	1970-08-28	Neue basisch substituierte ter tiare Butanole

Publications (1)

Publication Number	Publication Date
SU420170A3 true SU420170A3 (2)	1974-03-15

Family

ID=5780991

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SU1691523A SU420170A3 (2)	1970-08-28	1970-09-29
SU1691950A SU421179A3 (2)	1970-08-28	1970-09-29

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SU1691950A SU421179A3 (2)	1970-08-28	1970-09-29

Country Status (9)

Country	Link
KR (2)	KR780000213B1 (2)
AT (3)	AT310723B (2)
BG (2)	BG17747A3 (2)
CS (2)	CS168544B2 (2)
DE (1)	DE2042750A1 (2)
ES (3)	ES385471A1 (2)
PL (1)	PL84543B1 (2)
RO (2)	RO59184A (2)
SU (2)	SU420170A3 (2)

1970
- 1970-08-28 DE DE19702042750 patent/DE2042750A1/de active Pending
- 1970-09-29 SU SU1691523A patent/SU420170A3/ru active
- 1970-09-29 SU SU1691950A patent/SU421179A3/ru active
- 1970-10-02 BG BG017130A patent/BG17747A3/xx unknown
- 1970-10-02 BG BG017131A patent/BG17748A3/xx unknown
- 1970-10-06 CS CS788*[A patent/CS168544B2/cs unknown
- 1970-10-06 CS CS787*[A patent/CS168543B2/cs unknown
- 1970-10-12 PL PL1970174654A patent/PL84543B1/pl unknown
- 1970-10-12 KR KR7001422A patent/KR780000213B1/ko not_active Expired
- 1970-10-13 AT AT312472A patent/AT310723B/de not_active IP Right Cessation
- 1970-10-13 RO RO67024A patent/RO59184A/ro unknown
- 1970-10-13 AT AT312372A patent/AT308073B/de not_active IP Right Cessation
- 1970-10-13 AT AT312572A patent/AT308074B/de active
- 1970-10-13 RO RO67025A patent/RO58297A/ro unknown
- 1970-11-12 ES ES385471A patent/ES385471A1/es not_active Expired
- 1970-11-12 ES ES385473A patent/ES385473A1/es not_active Expired
- 1970-11-12 ES ES385472A patent/ES385472A1/es not_active Expired
1978
- 1978-01-28 KR KR7800224A patent/KR780000230B1/ko not_active Expired

Also Published As

Publication number	Publication date
CS168543B2 (2)	1976-06-29
ES385473A1 (es)	1973-05-01
DE2042750A1 (de)	1972-03-02
AT308073B (de)	1973-06-25
SU421179A3 (2)	1974-03-25
ES385471A1 (es)	1973-05-01
PL84543B1 (2)	1976-04-30
KR780000230B1 (en)	1978-07-01
RO58297A (2)	1975-07-15
CS168544B2 (2)	1976-06-29
AT310723B (de)	1973-10-10
AT308074B (de)	1973-06-25
KR780000213B1 (en)	1978-06-12
BG17748A3 (bg)	1973-12-25
RO59184A (2)	1976-02-15
ES385472A1 (es)	1973-05-01
BG17747A3 (bg)	1973-12-25

Publication	Publication Date	Title
CA1175431A (en)	1984-10-02	Tri-substituted imidazole derivatives, processes for their manufacture, pharmaceutical preparations containing them, and their use
US3541119A (en)	1970-11-17	Method of producing unsaturated sulfones
NO781450L (no)	1978-10-27	Fremgangsmaate for fremstilling av nye n-(1-(3-benzoylpropyl)-4-piperidyl)-sulfonsyreamider
Hilbert et al.	1934	Action of alkali and ammonia on 2, 4-dialkoxypyrimidines
SU420170A3 (2)	1974-03-15
SU419022A3 (2)	1974-03-05
EP1869001B1 (de)	2011-01-12	Substituierte tetrahydroisochinoline als mmp-inhibitoren, verfahren zu ihrer herstellung und ihre verwendung als medikament
SU1194272A3 (ru)	1985-11-23	Способ получени производных индолизина или их солей с органической или неорганической кислотой
SU588917A3 (ru)	1978-01-15	Способ получени 1/2-( -нафтилокси)-этил/-3метилпиразолона-5
US4628083A (en)	1986-12-09	2-hydroxy-5-(arylazo)-benzene alkanoic acids
EP0213295B1 (de)	1991-04-10	Neue Thieno-1,2-thiazolderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
EP0371342B1 (de)	1994-12-14	2-Halogensubstituierte N-Indolylethyl-sulfonsäureamide, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimitteln
DE2352012A1 (de)	1974-05-09	Neue aliphatisch substituierte arylchalkogeno-kohlenwasserstoffderivate und verfahren zu ihrer herstellung
CH450420A (de)	1968-01-31	Verfahren zur Herstellung von a-(3-Indolyl)-niederaliphatischen Säuren
SU489327A3 (ru)	1975-10-25	Способ получени четырех замещенных имидазолинов
SU421186A3 (ru)	1974-03-25	Способ получения производных 17-аза-16-кетостероидов
US3749750A (en)	1973-07-31	Alkyl esters of substituted phenylsulfonyl alkanoic acids
US3014925A (en)	1961-12-26	Unsaturated mevalonic acid
SU484686A3 (ru)	1975-09-15	Способ получени 2-замещенных 5-сульфамоилбензойных кислот
SU596169A3 (ru)	1978-02-28	Способ получени производных 4н-бензо/4,5/-циклогепта/1,2-в/ тиофена или их солей
CH606071A5 (en)	1978-10-13	Fibrinolytic anhydro-furanose ether derivs.
SU1128834A3 (ru)	1984-12-07	Способ получени производных 4-оксо @
SU528871A3 (ru)	1976-09-15	Способ получени производных 2-(1н) -хиназолинона
DE1568250C3 (de)	1974-10-10	Verfahren zur Herstellung von 3-Oxo-7 alpha-methyl-l 7-äthylendioxy-Delta hoch 1,4 androstadien
AT215993B (de)	1961-07-10	Verfahren zur Herstellung von neuen 4-Oxo-2-(halogenalkyl)-2,3-dihydro-[benzo-1,3-oxazinen]