UA77657C2 - Non-steroidal inflammation inhibitors - Google Patents
Non-steroidal inflammation inhibitors Download PDFInfo
- Publication number
- UA77657C2 UA77657C2 UA2003021765A UA2003021765A UA77657C2 UA 77657 C2 UA77657 C2 UA 77657C2 UA 2003021765 A UA2003021765 A UA 2003021765A UA 2003021765 A UA2003021765 A UA 2003021765A UA 77657 C2 UA77657 C2 UA 77657C2
- Authority
- UA
- Ukraine
- Prior art keywords
- methyl
- hydroxy
- benzoxazin
- trifluoromethylvaleroylamino
- fluorophenyl
- Prior art date
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- 206010061218 Inflammation Diseases 0.000 title claims abstract description 17
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- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
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- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Endocrinology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10038639A DE10038639A1 (de) | 2000-07-28 | 2000-07-28 | Nichtsteroidale Entzündungshemmer |
| PCT/EP2001/008501 WO2002010143A1 (de) | 2000-07-28 | 2001-07-23 | Nichtsteroidale entzündungshemmer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA77657C2 true UA77657C2 (en) | 2007-01-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2003021765A UA77657C2 (en) | 2000-07-28 | 2001-07-23 | Non-steroidal inflammation inhibitors |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US6777409B2 (et) |
| EP (1) | EP1309571A1 (et) |
| JP (1) | JP2004505068A (et) |
| KR (1) | KR20030019626A (et) |
| CN (2) | CN1915231A (et) |
| AU (2) | AU8200901A (et) |
| BG (1) | BG107488A (et) |
| BR (1) | BR0112786A (et) |
| CA (1) | CA2417444A1 (et) |
| CZ (1) | CZ2003216A3 (et) |
| DE (1) | DE10038639A1 (et) |
| EA (1) | EA005926B1 (et) |
| EE (1) | EE200300043A (et) |
| HR (1) | HRP20030148A2 (et) |
| HU (1) | HUP0301344A3 (et) |
| IL (1) | IL154143A0 (et) |
| MX (1) | MXPA02012933A (et) |
| NO (1) | NO20030406L (et) |
| NZ (1) | NZ523822A (et) |
| PE (1) | PE20020230A1 (et) |
| PL (1) | PL366336A1 (et) |
| SK (1) | SK812003A3 (et) |
| TW (1) | TWI282336B (et) |
| UA (1) | UA77657C2 (et) |
| WO (1) | WO2002010143A1 (et) |
| YU (1) | YU5503A (et) |
| ZA (1) | ZA200301639B (et) |
Families Citing this family (138)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DE10346940B3 (de) * | 2003-10-06 | 2005-06-16 | Schering Ag | Substituierte Pentanole, ihre Verwendung zur Herstellung von Arzneimitteln speziell Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate |
| US7238707B2 (en) | 2000-07-28 | 2007-07-03 | Schering Ag | Substituted pentanols, a process for their production and their use as anti-inflammatory agents |
| AU2003202216A1 (en) | 2002-01-14 | 2003-07-30 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations containing them and uses thereof |
| PL372490A1 (en) * | 2002-03-11 | 2005-07-25 | Schering Aktiengesellschaft | 5-{2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino}-phtalide and related compounds with progesterone receptor modulating activity for use in fertility control and hormone replacement therapy |
| EP1344776A1 (en) * | 2002-03-11 | 2003-09-17 | Schering Aktiengesellschaft | 5- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -phtalide and 6- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -4-methyl-2,3-benzoxazin-1-one derivatives with progesterone receptor modulating activity for use in fertility control, hormone replacement therapy and the treatment of gynecological disorders |
| CA2478156C (en) * | 2002-03-26 | 2011-02-15 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| WO2003082787A1 (en) | 2002-03-26 | 2003-10-09 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| US6897224B2 (en) * | 2002-04-02 | 2005-05-24 | Schering Ag | Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors |
| DE10215316C1 (de) * | 2002-04-02 | 2003-12-18 | Schering Ag | Chinolin- und Isochinolin-Derivate, ein pharmazeutisches Mittel und ihre Verwendung als Entzündungshemmer |
| US7186864B2 (en) | 2002-05-29 | 2007-03-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| US7074806B2 (en) | 2002-06-06 | 2006-07-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| JP2006504678A (ja) | 2002-08-21 | 2006-02-09 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | グルココルチコイドミメチックス、その製造方法、その医薬組成物、及び使用 |
| WO2004019935A1 (en) * | 2002-08-29 | 2004-03-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | -3 (sulfonamidoethyl) -indole derivaties for use as glucocorticoid mimetics in the treatment of inflammatory, allergic and proliferative diseases |
| CA2512257A1 (en) | 2003-01-03 | 2004-07-29 | Boehringer Ingelheim Pharmaceuticals, Inc. | 1-propanol and 1-propylamine derivatives and their use as glucocorticoid ligands |
| WO2004071389A2 (en) * | 2003-02-15 | 2004-08-26 | Glaxo Group Limited | Non-steroidal infalmmation inhibitors |
| US20040224992A1 (en) * | 2003-02-27 | 2004-11-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| AR044519A1 (es) | 2003-05-02 | 2005-09-14 | Novartis Ag | Derivados de piridin-tiazol amina y de pirimidin-tiazol amina |
| US20050090559A1 (en) * | 2003-07-01 | 2005-04-28 | Markus Berger | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents |
| EA200600148A1 (ru) * | 2003-07-01 | 2006-08-25 | Шеринг Акциенгезельшафт | Гетероциклически замещённые производные пентанола, способ их получения и их применение в качестве ингибиторов воспаления |
| UY28526A1 (es) | 2003-09-24 | 2005-04-29 | Boehringer Ingelheim Pharma | Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos |
| PT1670458E (pt) | 2003-10-08 | 2007-03-30 | Schering Ag | Derivados de tetra-hidronaftaleno, processo para a sua preparação e utilização como inibidor de inflamação |
| US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| DE10347385A1 (de) * | 2003-10-08 | 2005-05-12 | Schering Ag | Umgelagerte Pentanole, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| US7638515B2 (en) | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| DE102004017662B3 (de) * | 2004-04-05 | 2005-12-08 | Schering Ag | Mehrfach substituierte Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| US7507843B2 (en) | 2003-10-16 | 2009-03-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols |
| GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
| US7795272B2 (en) | 2004-03-13 | 2010-09-14 | Boehringer Ingelheim Pharmaceutical, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof |
| US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| WO2006000398A1 (en) * | 2004-06-28 | 2006-01-05 | Glaxo Group Limited | 2,3-benzoxazin derivatives as non-steroidal glucocorticoid receptor modulators |
| WO2006000401A1 (en) * | 2004-06-28 | 2006-01-05 | Glaxo Group Limited | Substituted oxazines as glucocorticoid receptor modulators |
| GB0418045D0 (en) | 2004-08-12 | 2004-09-15 | Glaxo Group Ltd | Compounds |
| DE102004044680B3 (de) * | 2004-09-09 | 2006-06-08 | Schering Ag | Alkyliden-Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate |
| US20060084652A1 (en) * | 2004-09-09 | 2006-04-20 | Stefan Baeurle | Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
| GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
| GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
| DE102004063227A1 (de) * | 2004-12-22 | 2006-07-06 | Schering Ag | Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| US20060167025A1 (en) * | 2004-12-22 | 2006-07-27 | Markus Berger | Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs |
| CA2592514A1 (en) * | 2004-12-27 | 2006-07-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| JP2006213674A (ja) * | 2005-02-07 | 2006-08-17 | Ube Ind Ltd | ４−ホルミルテトラヒドロピラン化合物の製法 |
| US20060229305A1 (en) * | 2005-03-22 | 2006-10-12 | Markus Berger | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| DE102005014089A1 (de) * | 2005-03-22 | 2006-09-28 | Schering Ag | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| JP2006265173A (ja) * | 2005-03-24 | 2006-10-05 | Sumitomo Chemical Co Ltd | グルココルチコイド受容体リガンド結合ドメインとリガンドとの複合体を含む結晶 |
| DE102005017286B3 (de) * | 2005-04-14 | 2006-12-28 | Schering Ag | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6245804B1 (en) | 1997-05-30 | 2001-06-12 | Schering Aktiengesellschaft | Nonsteroidal gestagens |
| DE19723722A1 (de) * | 1997-05-30 | 1998-12-10 | Schering Ag | Nichtsteroidale Gestagene |
| DE19856475A1 (de) * | 1998-11-27 | 2000-05-31 | Schering Ag | Nichtsteroidale Entzündungshemmer |
| JP3464405B2 (ja) * | 1999-02-18 | 2003-11-10 | 阪神化成工業株式会社 | 多層薄肉容器 |
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