YU91802A - Derivati 3-azabiciklo(3.1.0.)heksana koji imaju afinitet prema receptoru opijata - Google Patents

Derivati 3-azabiciklo(3.1.0.)heksana koji imaju afinitet prema receptoru opijata

Info

Publication number: YU91802A
Authority: YU; Yugoslavia
Prior art keywords: azabicyclo; opiate; pharmaceutically; opioid receptor; useful
Prior art date: 2000-06-23

Application number

YU91802A

Other languages

English (en)

Serbo-Croatian (sh)

Inventor

Bernard Joseph Banks

Douglas James Critcher

Ashley Edward Fenwick

David Morris Gethin

Graham Lunn

Original Assignee

Pfizer Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-23

Filing date

2001-06-07

Publication date

2006-05-25

2001-06-07 Application filed by Pfizer Inc. filed Critical Pfizer Inc.

2006-05-25 Publication of YU91802A publication Critical patent/YU91802A/sh

Links

108090000137 Opioid Receptors Proteins 0.000 title abstract 3
102000003840 Opioid Receptors Human genes 0.000 title abstract 3
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical class CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 title 1
208000007848 Alcoholism Diseases 0.000 abstract 1
206010003645 Atopy Diseases 0.000 abstract 1
206010010774 Constipation Diseases 0.000 abstract 1
206010012434 Dermatitis allergic Diseases 0.000 abstract 1
208000030814 Eating disease Diseases 0.000 abstract 1
208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
206010019196 Head injury Diseases 0.000 abstract 1
206010028813 Nausea Diseases 0.000 abstract 1
208000012488 Opiate Overdose Diseases 0.000 abstract 1
101100244562 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) oprD gene Proteins 0.000 abstract 1
201000001880 Sexual dysfunction Diseases 0.000 abstract 1
206010047700 Vomiting Diseases 0.000 abstract 1
201000008937 atopic dermatitis Diseases 0.000 abstract 1
208000010668 atopic eczema Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
108700023159 delta Opioid Receptors Proteins 0.000 abstract 1
102000048124 delta Opioid Receptors Human genes 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
235000014632 disordered eating Nutrition 0.000 abstract 1
208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
102000048260 kappa Opioid Receptors Human genes 0.000 abstract 1
102000051367 mu Opioid Receptors Human genes 0.000 abstract 1
230000008693 nausea Effects 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1
230000001823 pruritic effect Effects 0.000 abstract 1
231100000872 sexual dysfunction Toxicity 0.000 abstract 1
230000035939 shock Effects 0.000 abstract 1
208000017520 skin disease Diseases 0.000 abstract 1
230000000391 smoking effect Effects 0.000 abstract 1
230000008673 vomiting Effects 0.000 abstract 1
108020001588 κ-opioid receptors Proteins 0.000 abstract 1
108020001612 μ-opioid receptors Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Nutrition Science (AREA)
Gynecology & Obstetrics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)

YU91802A 2000-06-23 2001-06-07 Derivati 3-azabiciklo(3.1.0.)heksana koji imaju afinitet prema receptoru opijata YU91802A (sh)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0015562.2A GB0015562D0 (en)	2000-06-23	2000-06-23	Heterocycles

Publications (1)

Publication Number	Publication Date
YU91802A true YU91802A (sh)	2006-05-25

Family

ID=9894368

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU91802A YU91802A (sh)	2000-06-23	2001-06-07	Derivati 3-azabiciklo(3.1.0.)heksana koji imaju afinitet prema receptoru opijata

Country Status (34)

Country	Link
EP (1)	EP1292574A1 (pl)
JP (1)	JP2004512263A (pl)
KR (1)	KR20040002386A (pl)
CN (1)	CN1639121A (pl)
AP (1)	AP2002002698A0 (pl)
AR (1)	AR028969A1 (pl)
AU (1)	AU781837B2 (pl)
BG (1)	BG107329A (pl)
BR (1)	BR0111867A (pl)
CA (1)	CA2412188A1 (pl)
CZ (1)	CZ20023967A3 (pl)
DO (1)	DOP2001000187A (pl)
DZ (1)	DZ3368A1 (pl)
EA (1)	EA005117B1 (pl)
GB (1)	GB0015562D0 (pl)
HR (1)	HRP20020998A2 (pl)
HU (1)	HUP0301228A3 (pl)
IL (1)	IL153427A0 (pl)
IS (1)	IS6637A (pl)
MA (1)	MA26915A1 (pl)
MX (1)	MXPA02012878A (pl)
NO (1)	NO20026168L (pl)
NZ (1)	NZ523141A (pl)
OA (1)	OA12293A (pl)
PA (1)	PA8519401A1 (pl)
PE (1)	PE20020253A1 (pl)
PL (1)	PL365956A1 (pl)
SK (1)	SK17172002A3 (pl)
TN (1)	TNSN01094A1 (pl)
UA (1)	UA73176C2 (pl)
UY (1)	UY26787A1 (pl)
WO (1)	WO2001098267A1 (pl)
YU (1)	YU91802A (pl)
ZA (1)	ZA200210278B (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE60226161T2 (de) *	2001-10-22	2009-07-02	Pfizer Products Inc., Groton	3-azabicyclo[3.1.0]hexan derivative als antagonisten der opioid rezeptoren
CN100411618C (zh) *	2002-05-17	2008-08-20	迪欧加药品公司	有效的选择性阿片受体调制剂化合物的用途
DE10259245A1 (de)	2002-12-17	2004-07-01	Merck Patent Gmbh	Derivate des Asimadolins mit kovalent gebundenen Säuren
ATE451364T1 (de)	2004-02-23	2009-12-15	Glaxo Group Ltd	Als modulatoren des dopamin-d3-rezeptors geeignete azabicycloä3.1.0ühexanderivate
GB0507680D0 (en) *	2005-04-15	2005-05-25	Glaxo Group Ltd	Compounds
ATE484502T1 (de) *	2005-06-14	2010-10-15	Glaxo Group Ltd	Neue verbindungen
WO2007113258A1 (en) *	2006-04-03	2007-10-11	Glaxo Group Limited	Azabicyclo [3. 1. o] hexane derivatives as modulators of dopamine d3 receptors
EP2636407A3 (en)	2007-03-30	2013-11-06	Tioga Pharmaceuticals, Inc.	Kappa-opiate agonists for the treatment of diarrhea-predominant and alternating irritable bowel syndrome
TWI423801B (zh) *	2007-08-27	2014-01-21	Theravance Inc	作為μ類鴉片受體拮抗劑之８－氮雜雙環〔３．２．１〕辛基－２－羥基苯甲醯胺化合物
ES2645725T3 (es)	2010-06-11	2017-12-07	Rhodes Technologies	Procesos catalizados por metales de transición para la preparación de compuestos de N-alilo y uso de los mismos
BR112013007566A2 (pt)	2010-09-28	2016-08-02	Panacea Biotec Ltd	novos compostos bicíclicos
CA2927527C (en) *	2013-11-20	2021-06-01	Sanwa Kagaku Kenkyusho Co., Ltd.	Novel 3-azabicyclo[3.1.0]hexane derivative and use thereof as u-opioid receptor antagonist
HK1246778A1 (zh)	2015-05-20	2018-09-14	株式会社三和化学研究所	一种新型的3-氮杂双环[3.1.0]己烷衍生物的盐的晶体以及其医药应用
JP7185633B2 (ja)	2017-02-17	2022-12-07	トレベナ・インコーポレイテッド	７員アザ複素環を含有するデルタ－オピオイド受容体調節化合物、その使用方法及び製造方法
BR112019016827A2 (pt)	2017-02-17	2020-04-07	Trevena Inc	compostos moduladores de receptor delta-opioide contendo aza-heterocíclico com 5 membros, métodos de uso e produção dos mesmos
EP3590511A4 (en)	2017-03-02	2020-09-02	Sanwa Kagaku Kenkyusho Co., Ltd	THERAPEUTIC AGENT FOR DISORDERS RELATED TO THE CONSUMPTION OF ALCOHOL
CN108250088B (zh) *	2018-01-04	2020-10-30	四川之江高新材料股份有限公司	N，n，n′-三甲基-n′-羟乙基双氨基乙基醚的制备方法
CN115825305B (zh) *	2022-10-21	2024-09-20	昆明理工大学	一种分子印迹固相微萃取纤维及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3065230A (en) *	1959-03-16	1962-11-20	Burroughs Wellcome Co	Azabicyclohexanes and method of preparing them
ATE110057T1 (de) *	1987-04-16	1994-09-15	Lilly Co Eli	Piperidine als opioid-antagoniste.
US5159081A (en) *	1991-03-29	1992-10-27	Eli Lilly And Company	Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists
DE4341403A1 (de) *	1993-12-04	1995-06-08	Basf Ag	N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
PE20001420A1 (es) *	1998-12-23	2000-12-18	Pfizer	Moduladores de ccr5
TWI244481B (en) *	1998-12-23	2005-12-01	Pfizer	3-azabicyclo[3.1.0]hexane derivatives useful in therapy

2000
- 2000-06-23 GB GBGB0015562.2A patent/GB0015562D0/en not_active Ceased
2001
- 2001-06-06 DO DO2001000187A patent/DOP2001000187A/es unknown
- 2001-06-07 WO PCT/IB2001/001035 patent/WO2001098267A1/en not_active Ceased
- 2001-06-07 YU YU91802A patent/YU91802A/sh unknown
- 2001-06-07 JP JP2002504223A patent/JP2004512263A/ja not_active Withdrawn
- 2001-06-07 AU AU62591/01A patent/AU781837B2/en not_active Ceased
- 2001-06-07 DZ DZ013368A patent/DZ3368A1/xx active
- 2001-06-07 HU HU0301228A patent/HUP0301228A3/hu unknown
- 2001-06-07 EA EA200201269A patent/EA005117B1/ru not_active IP Right Cessation
- 2001-06-07 BR BR0111867-6A patent/BR0111867A/pt not_active IP Right Cessation
- 2001-06-07 IL IL15342701A patent/IL153427A0/xx unknown
- 2001-06-07 SK SK1717-2002A patent/SK17172002A3/sk unknown
- 2001-06-07 AP APAP/P/2002/002698A patent/AP2002002698A0/en unknown
- 2001-06-07 MX MXPA02012878A patent/MXPA02012878A/es unknown
- 2001-06-07 PL PL01365956A patent/PL365956A1/pl not_active Application Discontinuation
- 2001-06-07 CA CA002412188A patent/CA2412188A1/en not_active Abandoned
- 2001-06-07 NZ NZ523141A patent/NZ523141A/en unknown
- 2001-06-07 OA OA1200200386A patent/OA12293A/en unknown
- 2001-06-07 CN CNA018116086A patent/CN1639121A/zh active Pending
- 2001-06-07 EP EP01936728A patent/EP1292574A1/en not_active Withdrawn
- 2001-06-07 KR KR1020027017503A patent/KR20040002386A/ko not_active Ceased
- 2001-06-07 HR HR20020998A patent/HRP20020998A2/hr not_active Application Discontinuation
- 2001-06-07 CZ CZ20023967A patent/CZ20023967A3/cs unknown
- 2001-06-12 PA PA20018519401A patent/PA8519401A1/es unknown
- 2001-06-21 PE PE2001000604A patent/PE20020253A1/es not_active Application Discontinuation
- 2001-06-21 UY UY26787A patent/UY26787A1/es not_active Application Discontinuation
- 2001-06-21 AR ARP010102957A patent/AR028969A1/es unknown
- 2001-06-22 TN TNTNSN01094A patent/TNSN01094A1/fr unknown
- 2001-07-06 UA UA20021210406A patent/UA73176C2/uk unknown
2002
- 2002-11-28 IS IS6637A patent/IS6637A/is unknown
- 2002-11-28 BG BG107329A patent/BG107329A/xx unknown
- 2002-12-16 MA MA26955A patent/MA26915A1/fr unknown
- 2002-12-19 ZA ZA200210278A patent/ZA200210278B/xx unknown
- 2002-12-20 NO NO20026168A patent/NO20026168L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EA200201269A1 (ru)	2003-06-26
SK17172002A3 (sk)	2004-09-08
MXPA02012878A (es)	2003-05-14
WO2001098267A1 (en)	2001-12-27
HUP0301228A3 (en)	2005-08-29
WO2001098267A8 (en)	2003-02-27
CZ20023967A3 (cs)	2004-02-18
IL153427A0 (en)	2003-07-06
AP2002002698A0 (en)	2002-12-31
HUP0301228A2 (hu)	2003-08-28
BR0111867A (pt)	2003-07-01
UA73176C2 (en)	2005-06-15
JP2004512263A (ja)	2004-04-22
AU781837B2 (en)	2005-06-16
UY26787A1 (es)	2002-01-31
ZA200210278B (en)	2003-12-19
AR028969A1 (es)	2003-05-28
IS6637A (is)	2002-11-28
AU6259101A (en)	2002-01-02
DOP2001000187A (es)	2002-03-30
GB0015562D0 (en)	2000-08-16
NO20026168D0 (no)	2002-12-20
TNSN01094A1 (fr)	2005-11-10
HRP20020998A2 (en)	2004-02-29
MA26915A1 (fr)	2004-12-20
BG107329A (en)	2003-07-31
EP1292574A1 (en)	2003-03-19
CA2412188A1 (en)	2001-12-27
PE20020253A1 (es)	2002-04-08
EA005117B1 (ru)	2004-10-28
PA8519401A1 (es)	2002-12-30
NZ523141A (en)	2005-06-24
NO20026168L (no)	2003-02-18
KR20040002386A (ko)	2004-01-07
DZ3368A1 (fr)	2001-12-27
OA12293A (en)	2004-03-18
CN1639121A (zh)	2005-07-13
PL365956A1 (pl)	2005-01-24

Publication	Publication Date	Title
BG107329A (en)	2003-07-31	3-azabicyclo(3.1.0) hexane derivatives having opioid receptor affinity
TW200503713A (en)	2005-02-01	Novel compounds
MY138478A (en)	2009-06-30	Benzazepine derivatives for the treatment of neurological disorders
TW200505921A (en)	2005-02-16	Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group
UA84930C2 (ru)	2008-12-10	Пиррольные соединения как ингибиторы протеинкиназ erk, их синтез и соответствующие промежуточные соединения
GEP20043366B (en)	2004-04-13	Benzothiophene Derivative Compounds Process of Preparation and Use Thereof
TW200624432A (en)	2006-07-16	Imidazo [1,2-a] pyridine compounds, compositions, uses and methods related thereto
WO2006116218A8 (en)	2007-02-22	Crystal forms of {[(2r)-7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-benzofuran-2-yl]methyl}amine hydrochloride
MA29623B1 (fr)	2008-07-01	Derives de pyrazolo [3, 4-d] azepine comme antagonistes d'histamine h3
DE602004024188D1 (de)	2009-12-31	Des opioid-rezeptors
MXPA05011018A (es)	2005-12-12	Compuestos de 4-fenil piperidna y sus usos como moduladores de receptores opioides.
EP1725536B8 (en)	2009-04-22	Imidazoline derivatives having cb1-antagonistic activity
WO2005075450A3 (en)	2006-03-30	Spiro-benzodioxoles and their use as cb1 antagonists
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