ZA841011B - Novel pharmacologically active compounds - Google Patents
Novel pharmacologically active compoundsInfo
- Publication number
- ZA841011B ZA841011B ZA841011A ZA841011A ZA841011B ZA 841011 B ZA841011 B ZA 841011B ZA 841011 A ZA841011 A ZA 841011A ZA 841011 A ZA841011 A ZA 841011A ZA 841011 B ZA841011 B ZA 841011B
- Authority
- ZA
- South Africa
- Prior art keywords
- active compounds
- pharmacologically active
- novel pharmacologically
- novel
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8300736A SE8300736D0 (sv) | 1983-02-11 | 1983-02-11 | Novel pharmacologically active compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA841011B true ZA841011B (en) | 1984-09-26 |
Family
ID=20349994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA841011A ZA841011B (en) | 1983-02-11 | 1984-02-10 | Novel pharmacologically active compounds |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5039806A (fr) |
| JP (1) | JPS59181277A (fr) |
| AT (1) | AT386825B (fr) |
| AU (1) | AU578891B2 (fr) |
| BE (1) | BE898880A (fr) |
| CH (1) | CH666892A5 (fr) |
| CY (1) | CY1555A (fr) |
| DE (1) | DE3404610A1 (fr) |
| DK (1) | DK59184A (fr) |
| FI (1) | FI840547A7 (fr) |
| FR (1) | FR2543551B1 (fr) |
| GB (3) | GB2134523B (fr) |
| IT (1) | IT1177553B (fr) |
| LU (1) | LU85209A1 (fr) |
| NL (1) | NL8400446A (fr) |
| NO (1) | NO840504L (fr) |
| NZ (1) | NZ207102A (fr) |
| SE (3) | SE8300736D0 (fr) |
| ZA (1) | ZA841011B (fr) |
Families Citing this family (111)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| US5077407A (en) * | 1983-07-01 | 1991-12-31 | The Upjohn Company | Substituted 2-[monoannelated (3,4-,4,5-, and 5,6-) pyridylalkylenesulfinyl]benzimidazoles |
| CA1259070A (fr) * | 1983-07-01 | 1989-09-05 | Upjohn Company (The) | Derives de substitution de 2-¬noyaux condenses (3,4- 4,5-, 5,6-)-pyridylalcoylenesulfinyl|- benzimidazoles |
| US4575554A (en) * | 1983-12-05 | 1986-03-11 | The Upjohn Company | Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents |
| ZW4585A1 (en) * | 1984-04-19 | 1985-11-20 | Hoffmann La Roche | Imidazole derivatives |
| EP0174717B1 (fr) | 1984-07-06 | 1992-01-22 | FISONS plc | Benzimidazoles, et leur préparation, formulation et application comme inhibiteur de sécrétion d'acide gastrique |
| SE8404065D0 (sv) * | 1984-08-10 | 1984-08-10 | Haessle Ab | Novel biologically active compounds |
| JPS6150979A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| US4619997A (en) * | 1984-09-06 | 1986-10-28 | The Upjohn Company | Substituted 2-pyridylmethylthio and sulfinyl-benzimidazoles as gastric antisecretory agents |
| KR890000387B1 (ko) * | 1984-09-24 | 1989-03-16 | 디 엎존 캄파니 | 2-(피리딜알켄술 피닐)벤즈 이미드아졸류의 n-치환 유도체의 제조방법 |
| AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
| IL76839A (en) * | 1984-10-31 | 1988-08-31 | Byk Gulden Lomberg Chem Fab | Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
| DE3509333A1 (de) * | 1985-03-15 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Substituierte benzimidazolderivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
| US5869513A (en) * | 1985-05-24 | 1999-02-09 | G. D. Searle & Co. | 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines |
| AU5768886A (en) | 1985-05-24 | 1986-11-27 | G.D. Searle & Co. | 2-((1-h-benzimidazol-2-ylsulfinyl)methyl)benzenamines |
| US4738975A (en) * | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
| DK337086A (da) * | 1985-08-12 | 1987-02-13 | Hoffmann La Roche | Benzimidazolderivater |
| SE8505112D0 (sv) * | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
| US6749864B2 (en) | 1986-02-13 | 2004-06-15 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
| US5433959A (en) * | 1986-02-13 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Stabilized pharmaceutical composition |
| CA1327010C (fr) * | 1986-02-13 | 1994-02-15 | Tadashi Makino | Compositions pharmaceutiques contenant un compose anti-ulcereux de type benzimidazole et sa production |
| EP0234485B1 (fr) * | 1986-02-20 | 1992-04-01 | Hoechst Aktiengesellschaft | Dérivés substitués du thiénoimidazole, procédés pour leur préparation, compositions pharmaceutiques les contenant et leur application comme inhibiteurs de la sécrétion du suc gastrique |
| JPS62201884A (ja) * | 1986-02-28 | 1987-09-05 | Tokyo Tanabe Co Ltd | ベンズイミダゾール誘導体及びその製造法 |
| EP0251294B1 (fr) * | 1986-07-01 | 1990-09-19 | Shionogi Seiyaku Kabushiki Kaisha | Dérivés substitués d'isoquinoline et agents anti-ulcères |
| US4772619A (en) * | 1986-07-17 | 1988-09-20 | G. D. Searle & Co. | [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines |
| US4687775A (en) * | 1986-07-17 | 1987-08-18 | G. D. Searle & Co. | 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles |
| US4721718A (en) * | 1986-08-18 | 1988-01-26 | G. D. Searle & Co. | 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers |
| SE8604566D0 (sv) * | 1986-10-27 | 1986-10-27 | Haessle Ab | Novel compunds |
| EP0786461A1 (fr) * | 1986-11-13 | 1997-07-30 | Eisai Co., Ltd. | Dérivés de pyridine, compositions pharmaceutiques les contenant, leur utilisation pour la préparation de médicaments de valeur thérapeutique ou préventive et procédé pour leur préparation |
| FI90544C (fi) * | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
| NZ234564A (en) * | 1986-11-21 | 1991-04-26 | Haessle Ab | 1-substituted benzimidazoles and pharmaceutical compositions |
| US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
| US4942245A (en) * | 1987-04-20 | 1990-07-17 | Kyorin Pharmaceutical Co., Ltd. | Benzimidazole Derivatives |
| US4839365A (en) * | 1987-05-19 | 1989-06-13 | Shinogi & Co., Ltd. | Thienopyridine derivatives useful in treating gastric ulcers |
| JP2718945B2 (ja) * | 1987-06-17 | 1998-02-25 | エーザイ株式会社 | ピリジン誘導体及びそれを含有する潰瘍治療剤 |
| FI96860C (fi) * | 1987-06-17 | 1996-09-10 | Eisai Co Ltd | Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi |
| US4920230A (en) * | 1987-06-29 | 1990-04-24 | Takeda Chemical Industries, Ltd. | Method of producing nitrogen-containing heteroaromatic compounds having an alkoxy group |
| WO1989000566A1 (fr) * | 1987-07-21 | 1989-01-26 | Yoshitomi Pharmaceutical Industries, Ltd. | Composes de pyridine et leurs utilisations en medecine |
| WO1990003373A1 (fr) * | 1988-09-20 | 1990-04-05 | Hisamitsu Pharmaceutical Co., Inc. | NOUVEAUX DERIVES DE DIBENZ[b,e]OXEPINE |
| AT391693B (de) * | 1988-11-15 | 1990-11-12 | Cl Pharma | Verfahren zur herstellung von 3-5-dimethyl-4methoxypyridinderivaten sowie neues zwischenprodukt hierfuer |
| IE64199B1 (en) * | 1988-12-22 | 1995-07-12 | Haessle Ab | Compound with gastric acid inhibitory effect and process for its preparation |
| US4965269A (en) * | 1989-12-20 | 1990-10-23 | Ab Hassle | Therapeutically active chloro substituted benzimidazoles |
| SE9002043D0 (sv) * | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| SE9002206D0 (sv) | 1990-06-20 | 1990-06-20 | Haessle Ab | New compounds |
| EP0567643A4 (fr) * | 1991-01-16 | 1995-07-19 | Yoshitomi Pharmaceutical | Compose de pyridine utilise comme medicament selectif et nouveau compose de pyridine. |
| ES2037609B1 (es) * | 1991-12-02 | 1994-04-01 | Techquin Etablissment | Procedimiento para la obtencion del 2-(((3-metil-4-(2,2,2-trifluroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol. |
| ES2037608B1 (es) * | 1991-12-02 | 1994-04-01 | Techquin Etablissment | Procedimiento para la obtencion del 2 (((3-metil-4-(2,2,2,-trifluoroetoxi)-2-piridinil)-metil)sulfinil)-1h-benzimidazol". |
| KR950701921A (ko) * | 1992-06-01 | 1995-05-17 | 고야 다다시 | 피리딘 화합물 및 이의 제약학적 용도(pyridine compound and medicinal use thereof) |
| US5504082A (en) * | 1992-06-01 | 1996-04-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridine compound and pharmaceutical compostions |
| PL307026A1 (en) * | 1992-07-08 | 1995-05-02 | Monsanto Co | Method of producing ppaliative effect in respect to swine gastric ulcers |
| RU2126252C1 (ru) * | 1992-07-28 | 1999-02-20 | Астра Актиеболаг | Препарат для инъекций и набор для инъекций, содержащие омепразол и его аналоги |
| TW280770B (fr) | 1993-10-15 | 1996-07-11 | Takeda Pharm Industry Co Ltd | |
| JPH09509143A (ja) | 1993-12-01 | 1997-09-16 | ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換アミノアルキルアミノピリジン |
| KR0142815B1 (ko) * | 1994-12-02 | 1998-07-15 | 정도언 | 신규한 5-피롤릴-6-할로게노-2피리딜메틸설피닐벤즈이미다졸 유도체 |
| KR0179401B1 (ko) * | 1994-02-28 | 1999-03-20 | 송택선 | 신규한 5-피롤릴-2-피리딜메틸설피닐벤즈이미다졸 유도체 |
| WO1995029897A1 (fr) * | 1994-04-29 | 1995-11-09 | G.D. Searle & Co. | Procede d'utilisation d'inhibiteurs de (h+/k+)atpase comme agents antiviraux |
| FI964908L (fi) * | 1994-06-10 | 1996-12-09 | Byk Gulden Lomberg Chem Fab | Helicobacter-bakteerien torjuntaan tarkoitetut tiopyridiinit |
| US6207198B1 (en) * | 1995-09-21 | 2001-03-27 | Schwarz Pharma Ag | Composition containing an acid-labile omeprazole and process for its preparation |
| US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
| US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US7230014B1 (en) | 1997-10-14 | 2007-06-12 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
| DK2263660T3 (en) | 1998-05-18 | 2018-01-02 | Takeda Pharmaceuticals Co | Orally disintegrating tablets. |
| NZ510180A (en) * | 1998-08-10 | 2002-11-26 | Univ California | Prodrugs of the pyridyl-methylsulphonyl-benzimidazole type proton pump inhibitors |
| US6093734A (en) * | 1998-08-10 | 2000-07-25 | Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin | Prodrugs of proton pump inhibitors |
| WO2000027841A1 (fr) * | 1998-11-06 | 2000-05-18 | Dong-A Pharmaceutical Co., Ltd. | Procede de preparation de derives de sulfure |
| US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
| RU2232159C2 (ru) * | 1999-07-29 | 2004-07-10 | Регентский Совет Университета Калифорнии | Производные бензимидазола и фармацевтические композиции, содержащие пролекарство ингибитора протонного насоса |
| US6262085B1 (en) * | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
| DE60023154T2 (de) * | 1999-08-26 | 2006-06-22 | Aaipharma Inc. | Alkoxy-substituierte benzimidazolverbindungen , diese enthaltende arzneimittel und ihre verwendung |
| US6369087B1 (en) * | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| EP1595879A3 (fr) * | 1999-08-26 | 2010-01-27 | aaiPharma Inc. | Composés de benzimidazole substitués par un alkoxy, préparations pharmaceutiques contenant ces derniers, et procédés d'utilisation |
| WO2001062248A1 (fr) | 2000-02-24 | 2001-08-30 | Kopran Research Laboratories Limited | Derives de benzimidazole antiulcereux a acidite stable administrables oralement |
| US6544556B1 (en) * | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
| WO2002026210A2 (fr) * | 2000-09-29 | 2002-04-04 | Geneva Pharmaceuticals Inc. | Formulation d'inhibiteur de la pompe à protons |
| PL368563A1 (en) * | 2001-02-02 | 2005-04-04 | Teva Pharmaceutical Industries Ltd. | Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1h-benzimidazoles |
| DE10135050A1 (de) * | 2001-07-09 | 2003-02-06 | Schering Ag | 1-Ary1-2-N-, S- oder O-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate |
| US6903126B2 (en) * | 2001-07-09 | 2005-06-07 | Schering Ag | 1-Aryl-2-N-, S- or O-substituted benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives |
| EP1437352A4 (fr) * | 2001-09-25 | 2004-12-08 | Takeda Chemical Industries Ltd | Compose de benzymidazole, procede de production et d'utilisation de celui-ci |
| US20040006111A1 (en) * | 2002-01-25 | 2004-01-08 | Kenneth Widder | Transmucosal delivery of proton pump inhibitors |
| US20030228363A1 (en) * | 2002-06-07 | 2003-12-11 | Patel Mahendra R. | Stabilized pharmaceutical compositons containing benzimidazole compounds |
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| IT1013069B (it) * | 1973-03-29 | 1977-03-30 | Du Pont | Processo di preparazione di 2 benzimidazoltiolo |
| US3857769A (en) * | 1973-11-08 | 1974-12-31 | Scm Corp | Photopolymerizable coating compositions and process for making same which contains a thioxanthone and an activated halogenated azine compound as sensitizers |
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| SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| HU178454B (en) * | 1979-07-02 | 1982-05-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing new isoquinoline derivatives containing sulphur |
| GB2048880A (en) * | 1979-05-09 | 1980-12-17 | Rhone Poulenc Ind | Isoquinoline derivatives |
| US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
| CH644116A5 (de) * | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
| IL66340A (en) * | 1981-08-13 | 1986-08-31 | Haessle Ab | Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation |
| US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
| SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| JPS6150979A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
-
1983
- 1983-02-11 SE SE8300736A patent/SE8300736D0/xx unknown
-
1984
- 1984-02-09 DE DE3404610A patent/DE3404610A1/de not_active Withdrawn
- 1984-02-10 CH CH660/84A patent/CH666892A5/de not_active IP Right Cessation
- 1984-02-10 NO NO840504A patent/NO840504L/no unknown
- 1984-02-10 NZ NZ207102A patent/NZ207102A/en unknown
- 1984-02-10 FI FI840547A patent/FI840547A7/fi not_active Application Discontinuation
- 1984-02-10 AT AT0043584A patent/AT386825B/de not_active IP Right Cessation
- 1984-02-10 LU LU85209A patent/LU85209A1/fr unknown
- 1984-02-10 DK DK59184A patent/DK59184A/da not_active Application Discontinuation
- 1984-02-10 GB GB08403540A patent/GB2134523B/en not_active Expired
- 1984-02-10 ZA ZA841011A patent/ZA841011B/xx unknown
- 1984-02-10 JP JP59022067A patent/JPS59181277A/ja active Pending
- 1984-02-10 NL NL8400446A patent/NL8400446A/nl not_active Application Discontinuation
- 1984-02-10 FR FR8402093A patent/FR2543551B1/fr not_active Expired
- 1984-02-10 AU AU24456/84A patent/AU578891B2/en not_active Ceased
- 1984-02-10 BE BE0/212366A patent/BE898880A/fr unknown
- 1984-02-10 IT IT47675/84A patent/IT1177553B/it active
-
1986
- 1986-04-29 GB GB868610503A patent/GB8610503D0/en active Pending
- 1986-05-02 GB GB08610790A patent/GB2174988B/en not_active Expired
-
1987
- 1987-02-10 SE SE8700499A patent/SE8700499D0/xx not_active Application Discontinuation
- 1987-02-10 SE SE8700498A patent/SE8700498D0/xx not_active Application Discontinuation
-
1989
- 1989-09-18 US US07/408,719 patent/US5039806A/en not_active Expired - Fee Related
-
1991
- 1991-03-22 CY CY1555A patent/CY1555A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5039806A (en) | 1991-08-13 |
| SE8300736D0 (sv) | 1983-02-11 |
| IT8447675A0 (it) | 1984-02-10 |
| DE3404610A1 (de) | 1984-08-16 |
| DK59184A (da) | 1984-08-12 |
| FR2543551A1 (fr) | 1984-10-05 |
| DK59184D0 (da) | 1984-02-10 |
| GB8403540D0 (en) | 1984-03-14 |
| JPS59181277A (ja) | 1984-10-15 |
| GB2134523A (en) | 1984-08-15 |
| SE8700499L (sv) | 1987-02-10 |
| NL8400446A (nl) | 1984-09-03 |
| CY1555A (en) | 1991-03-22 |
| SE8700498L (sv) | 1987-02-10 |
| AT386825B (de) | 1988-10-25 |
| NZ207102A (en) | 1987-09-30 |
| ATA43584A (de) | 1988-03-15 |
| NO840504L (no) | 1984-08-13 |
| FI840547L (fi) | 1984-08-12 |
| GB2134523B (en) | 1987-08-12 |
| GB2174988A (en) | 1986-11-19 |
| GB2174988B (en) | 1987-08-26 |
| SE8700499D0 (sv) | 1987-02-10 |
| AU578891B2 (en) | 1988-11-10 |
| LU85209A1 (de) | 1985-09-12 |
| CH666892A5 (de) | 1988-08-31 |
| BE898880A (fr) | 1984-08-10 |
| SE8700498D0 (sv) | 1987-02-10 |
| FI840547A7 (fi) | 1984-08-12 |
| GB8610790D0 (en) | 1986-06-11 |
| IT1177553B (it) | 1987-08-26 |
| FI840547A0 (fi) | 1984-02-10 |
| FR2543551B1 (fr) | 1987-08-21 |
| AU2445684A (en) | 1984-08-16 |
| GB8610503D0 (en) | 1986-06-04 |
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