ZA875346B - 6-thioxanthines - Google Patents

6-thioxanthines

Info

Publication number
ZA875346B
ZA875346B ZA875346A ZA875346A ZA875346B ZA 875346 B ZA875346 B ZA 875346B ZA 875346 A ZA875346 A ZA 875346A ZA 875346 A ZA875346 A ZA 875346A ZA 875346 B ZA875346 B ZA 875346B
Authority
ZA
South Africa
Prior art keywords
group
alkyl
thioxanthines
cycloalkylalkyl
cycloalkyl group
Prior art date
Application number
ZA875346A
Other languages
English (en)
Inventor
Hofer Peter
Original Assignee
Euroceltique S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euroceltique S.A. filed Critical Euroceltique S.A.
Publication of ZA875346B publication Critical patent/ZA875346B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/22—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA875346A 1986-08-02 1987-07-21 6-thioxanthines ZA875346B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868618931A GB8618931D0 (en) 1986-08-02 1986-08-02 6-thioxanthines

Publications (1)

Publication Number Publication Date
ZA875346B true ZA875346B (en) 1988-01-27

Family

ID=10602146

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA875346A ZA875346B (en) 1986-08-02 1987-07-21 6-thioxanthines

Country Status (13)

Country Link
US (2) US4925847A (de)
EP (1) EP0256692B1 (de)
JP (1) JP2590120B2 (de)
AT (1) ATE80632T1 (de)
AU (1) AU601456B2 (de)
CA (1) CA1276147C (de)
DE (1) DE3781743T2 (de)
DK (1) DK161965C (de)
ES (1) ES2046204T3 (de)
GB (1) GB8618931D0 (de)
GR (1) GR3005997T3 (de)
IE (1) IE60510B1 (de)
ZA (1) ZA875346B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710503A (en) * 1985-02-07 1987-12-01 Euroceltique S.A. 6-thioxanthine derivatives
GB8618931D0 (en) * 1986-08-02 1986-09-10 Euro Celtique Sa 6-thioxanthines
JP2843634B2 (ja) * 1989-03-06 1999-01-06 協和醗酵工業株式会社 キサンチン誘導体
WO1990012797A1 (en) * 1989-04-19 1990-11-01 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Sulfer-containing xanthine derivatives as adenosin antagonists
US5290782A (en) * 1989-09-01 1994-03-01 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
JPH06102662B2 (ja) * 1989-09-01 1994-12-14 協和醗酵工業株式会社 キサンチン誘導体
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
EP0799040B1 (de) * 1994-12-13 2003-08-20 Euroceltique S.A. Dreifachsubstituierte thioxanthine
US6066641A (en) * 1994-12-13 2000-05-23 Euro-Celtique S.A. Aryl thioxanthines
US6268373B1 (en) 1995-06-07 2001-07-31 Euro-Celtique S.A. Trisubstituted thioxanthines
US6166041A (en) 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
AU2603197A (en) 1996-04-10 1997-10-29 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Use of an a1 adenosine receptor agonist to treat cerebral ischaemia
US6075016A (en) 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US6294541B1 (en) 1996-06-06 2001-09-25 Euro-Celtique S.A. Purine derivatives having phosphodiesterase IV inhibition activity
US5744473A (en) * 1996-09-16 1998-04-28 Euro-Celtique, S.A. PDE IV inhibitors: "bis-compounds"
DE19882892T1 (de) 1997-12-12 2001-02-22 Euro Celtique Sa Herstellung von 3-substituierten Adeninen und Imidazopyridinen
US6319928B1 (en) 1998-11-30 2001-11-20 Euro-Celtique, S.A. Purine derivatives having phosphodiesterase IV inhibition activity
AR029347A1 (es) 1999-04-02 2003-06-25 Euro Celtique Sa Compuesto de adenina, compuesto de isognanina y 2,6-ditioxantina como precursor del mismo, uso de dichos compuestos para preparar una composicion farmaceutica y dicha composicion farmaceutica
AU2223501A (en) 1999-12-24 2001-07-09 Kyowa Hakko Kogyo Co. Ltd. Fused purine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR188M (fr) * 1960-01-28 1961-02-20 May & Baker Ltd Nouveaux dérivés de la thioxanthine et les compositions pharmaceutiques qui les contiennent.
US3900474A (en) * 1973-05-14 1975-08-19 Kendall & Co Trifluoroalkyl, fluorobenzyl, pentafluorobenzyl, fluorobenzenesulfonyl, and pentafluorobenzenesulfonyl theophyllines
SE8002910L (sv) * 1980-04-18 1981-10-19 Draco Ab 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar
US4710503A (en) * 1985-02-07 1987-12-01 Euroceltique S.A. 6-thioxanthine derivatives
GB8618931D0 (en) * 1986-08-02 1986-09-10 Euro Celtique Sa 6-thioxanthines

Also Published As

Publication number Publication date
DK367787D0 (da) 1987-07-15
ES2046204T3 (es) 1994-02-01
GB8618931D0 (en) 1986-09-10
DK161965B (da) 1991-09-02
DK367787A (da) 1988-02-03
JPS6341478A (ja) 1988-02-22
DE3781743D1 (en) 1992-10-22
AU7628687A (en) 1988-02-04
IE60510B1 (en) 1994-07-27
JP2590120B2 (ja) 1997-03-12
IE872074L (en) 1988-02-02
AU601456B2 (en) 1990-09-13
GR3005997T3 (de) 1993-06-07
CA1276147C (en) 1990-11-13
US4925847A (en) 1990-05-15
EP0256692A2 (de) 1988-02-24
EP0256692B1 (de) 1992-09-16
DK161965C (da) 1992-02-10
ATE80632T1 (de) 1992-10-15
DE3781743T2 (de) 1993-03-25
EP0256692A3 (en) 1989-08-30
US5010081A (en) 1991-04-23

Similar Documents

Publication Publication Date Title
DE3781743D1 (en) 6-thioxanthine.
ES8704485A1 (es) Un procedimiento para la preparacion de derivados de piperazina 1,4-disustituidos.
PH30811A (en) Polypeptide compound and a process for preparationthereof.
AU1433588A (en) 1-phenyl-3-naphthalenyloxypropanamines
EP0270362A3 (de) Pyridinyl-Pyrimidin-Derivate, Verfahren zu deren Herstellung und diese als wirksamen Stoff enthaltendes fungicides Mittel
PT82368A (en) Substituted n-<(4-piperidinyl)alkyl> bicyclic condensed oxazol- and thiazolamines
TW235963B (de)
PT83104B (en) Novel guanidinomethylbenzoic acid derivatives
GR3005990T3 (de)
ES8706144A1 (es) Un procedimiento para preparar derivados de 1,8-naftiridina
EP0331078A3 (de) Verfahren zur Herstellung von optisch wirksamer 4-Oxo-1-Benzopyran-2-carbonsäure und deren Zwischenprodukte
ZA888799B (en) Derivatives of paraherquamide isolated from a permentation broth active as antiparasitic agents
EP0272596A3 (en) Theophyllinemethyldithiolan and theophyllinemethyldithianyl derivates, a method for their preparation and pharmaceutical compositions in which they are included
GR3007219T3 (de)
SE8601799L (sv) (-)-1beta-etyl-1alfa-hydroximetyl-1,2,3,4,6,7,12,12balfa-iktahydroindolo/2,3-a/-kinolizin, forfarande for dess framstellning och farmaceutiska beredningar innehallande densamma
EP0216323A3 (de) Derivate von Chinoloncarbonsäure und ihre Herstellung
DE3665593D1 (en) Peptide immunostimulants
DE69405999D1 (de) Pharmazeutisch wirksame enantiomere
GR3006223T3 (de)
AU2013888A (en) Uricosuric composition
GB2190587B (en) Prophylactic and curing composition for arteriosclerosis
EP0272849A3 (en) Use of 2-oxo-imidazolidine derivatives in the treatment of kidney diseases
EP0306863A3 (en) New cephem compounds and processes for preparation thereof
HU9401984D0 (en) New cephem compounds
MY101746A (en) 1,5-benzothiazepine derivatives, a process for preparing the same, pharmaceutical compositions as well as the use thereof.