ZA899795B - Compound with gastric acid inhibitory effect and process for its preparation - Google Patents

Compound with gastric acid inhibitory effect and process for its preparation

Info

Publication number
ZA899795B
ZA899795B ZA899795A ZA899795A ZA899795B ZA 899795 B ZA899795 B ZA 899795B ZA 899795 A ZA899795 A ZA 899795A ZA 899795 A ZA899795 A ZA 899795A ZA 899795 B ZA899795 B ZA 899795B
Authority
ZA
South Africa
Prior art keywords
compound
preparation
inhibitory effect
gastric acid
acid inhibitory
Prior art date
Application number
ZA899795A
Other languages
English (en)
Inventor
Arne Elof Brandstroem
Elof Brandstroem Arne
Per Lennart Lindberg
Lennart Lindberg Per
Gunnel Elisabeth Sunden
Elisabeth Sunden Gunnel
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of ZA899795B publication Critical patent/ZA899795B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA899795A 1988-12-22 1989-12-20 Compound with gastric acid inhibitory effect and process for its preparation ZA899795B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE19888804629A SE8804629D0 (sv) 1988-12-22 1988-12-22 New therapeutically active compounds

Publications (1)

Publication Number Publication Date
ZA899795B true ZA899795B (en) 1990-08-29

Family

ID=20374310

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA899794A ZA899794B (en) 1988-12-22 1989-12-20 New therapeutically active compound and a process for its preparation
ZA899795A ZA899795B (en) 1988-12-22 1989-12-20 Compound with gastric acid inhibitory effect and process for its preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA899794A ZA899794B (en) 1988-12-22 1989-12-20 New therapeutically active compound and a process for its preparation

Country Status (32)

Country Link
US (2) US5008278A (fr)
EP (1) EP0449940B1 (fr)
JP (1) JP2793906B2 (fr)
KR (1) KR910700249A (fr)
CN (1) CN1028231C (fr)
AR (1) AR248136A1 (fr)
AT (1) ATE127799T1 (fr)
AU (1) AU634741B2 (fr)
BG (1) BG60102B2 (fr)
CA (1) CA2005986C (fr)
DD (2) DD296078A5 (fr)
DE (1) DE68924273T2 (fr)
DK (1) DK170800B1 (fr)
EG (1) EG19303A (fr)
FI (2) FI913035A0 (fr)
GR (1) GR1002252B (fr)
HR (1) HRP920831A2 (fr)
HU (2) HU205926B (fr)
IE (1) IE894048L (fr)
IL (1) IL92798A0 (fr)
LT (2) LT3980B (fr)
LV (1) LV10187B (fr)
NZ (1) NZ231872A (fr)
PH (1) PH27400A (fr)
PL (1) PL161150B1 (fr)
PT (1) PT92648B (fr)
RO (1) RO110494B1 (fr)
RU (2) RU2073676C1 (fr)
SE (1) SE8804629D0 (fr)
WO (1) WO1990006925A1 (fr)
YU (1) YU46806B (fr)
ZA (2) ZA899794B (fr)

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TNSN95063A1 (fr) * 1994-05-27 1996-02-06 Astra Ab Nouveaux benzimidazoles substitues
EE03305B1 (et) * 1994-07-08 2000-12-15 Astra Aktiebolag Paljuosaline tableteeritud annusvorm I
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
DE19758573C2 (de) * 1997-11-26 2001-03-01 Implex Hear Tech Ag Fixationselement für ein implantierbares Mikrofon
CA2298823C (fr) * 1998-04-20 2011-06-07 Eisai Co., Ltd. Composition stabilisee comprenant un compose de type benzimidazole
SE9900274D0 (sv) * 1999-01-28 1999-01-28 Astra Ab New compound
TWI243672B (en) 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
RU2232159C2 (ru) * 1999-07-29 2004-07-10 Регентский Совет Университета Калифорнии Производные бензимидазола и фармацевтические композиции, содержащие пролекарство ингибитора протонного насоса
MXPA02003762A (es) 1999-10-20 2002-09-30 Eisai Co Ltd Metodos para estabilizar compuestos basados en benzimidazol.
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
US20040006111A1 (en) * 2002-01-25 2004-01-08 Kenneth Widder Transmucosal delivery of proton pump inhibitors
CA2480358A1 (fr) * 2002-03-26 2003-10-09 Dr. Reddy's Laboratories Limited Formes cristallines de rabeprazole sodique
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
US20040248942A1 (en) * 2003-02-20 2004-12-09 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
WO2005007117A2 (fr) * 2003-07-18 2005-01-27 Santarus, Inc. Formulation pharmaceutique et procede de traitement de troubles gastro-intestinaux lies a l'acidite
CA2531564C (fr) * 2003-07-18 2016-01-19 Santarus, Inc. Formulations pharmaceutiques utilisees pour inhiber une secretion acide et procede de fabrication associe
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
KR20060092255A (ko) 2003-09-26 2006-08-22 알자 코포레이션 고도의 약물적재를 제공하는 약물코팅제 및 그의 제조방법
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
RU2325960C2 (ru) * 2005-09-22 2008-06-10 Белорусский Национальный Технический Университет Способ получения товарной продукции на литейно-прокатном комплексе металлургического мини-завода
PL2046334T3 (pl) 2006-07-25 2015-02-27 Vecta Ltd Kompozycje i sposoby hamowania wydzielania kwasów żołądkowych z wykorzystaniem pochodnych małych kwasów dikarboksylowych w połączeniu z PPI
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
BRPI0918492A2 (pt) 2008-09-09 2015-12-01 Astrazeneca Ab uso de naproxen, ou sal farmaceuticamente aceitável do mesmo, e esomeprazol, ou sal farmaceuticamente aceitável do mesmo
EP2445499A4 (fr) 2009-06-25 2013-02-27 Astrazeneca Ab Procede pour le traitement d'un patient a risque de developer un ulcere associe a nsaid
WO2011080500A2 (fr) 2009-12-29 2011-07-07 Orexo Ab Nouvelle forme pharmaceutique destinée au traitement de troubles liés à l'acide gastrique
WO2011080501A2 (fr) 2009-12-29 2011-07-07 Orexo Ab Nouvelle forme pharmaceutique destinée au traitement de troubles liés à l'acide gastrique
WO2011080502A2 (fr) 2009-12-29 2011-07-07 Orexo Ab Nouvelle forme pharmaceutique destinée au traitement de troubles liés à l'acide gastrique
EP2601947A1 (fr) 2011-12-05 2013-06-12 Abo Bakr Mohammed Ali Al-Mehdar Combinaison à dose fixe pour le traitement de maladies associées à Hélicobacter pylori
UA115139C2 (uk) 2011-12-28 2017-09-25 Поузен Інк. Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту

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SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (fr) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
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SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
JPS6261978A (ja) * 1985-09-12 1987-03-18 Otsuka Pharmaceut Co Ltd ５−フルオロ−１ｈ−ベンズイミダゾ−ル誘導体
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JPS62201884A (ja) * 1986-02-28 1987-09-05 Tokyo Tanabe Co Ltd ベンズイミダゾール誘導体及びその製造法
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JPH0676323B2 (ja) * 1987-08-28 1994-09-28 東京田辺製薬株式会社 抗潰瘍剤

Also Published As

Publication number Publication date
DK122291A (da) 1991-06-24
ZA899794B (en) 1990-08-29
AU4817590A (en) 1990-07-10
DD296078A5 (de) 1991-11-21
AR248136A1 (es) 1995-06-30
LT3914B (en) 1996-04-25
ATE127799T1 (de) 1995-09-15
EG19303A (en) 1994-11-30
EP0449940B1 (fr) 1995-09-13
IL92798A0 (en) 1990-09-17
FI954768A0 (fi) 1995-10-06
WO1990006925A1 (fr) 1990-06-28
US5039808A (en) 1991-08-13
PL161150B1 (en) 1993-05-31
AU634741B2 (en) 1993-03-04
FI913035A7 (fi) 1991-06-20
CN1043713A (zh) 1990-07-11
GR1002252B (en) 1996-04-23
HU205926B (en) 1992-07-28
DK122291D0 (da) 1991-06-21
BG60102B2 (bg) 1993-10-29
FI954768A7 (fi) 1995-10-06
US5008278A (en) 1991-04-16
JPH04502461A (ja) 1992-05-07
JP2793906B2 (ja) 1998-09-03
RU2042673C1 (ru) 1995-08-27
DE68924273D1 (de) 1995-10-19
PH27400A (en) 1993-06-21
YU46806B (sh) 1994-06-10
DE68924273T2 (de) 1996-02-15
LTIP1721A (en) 1995-07-25
RO110494B1 (ro) 1996-01-30
CN1028231C (zh) 1995-04-19
FI954768L (fi) 1995-10-06
DK170800B1 (da) 1996-01-22
HU205927B (en) 1992-07-28
YU242689A (en) 1991-04-30
GR890100838A (el) 1991-03-15
LV10187B (en) 1995-04-20
CA2005986C (fr) 1999-08-03
IE894048L (en) 1990-06-22
HRP920831A2 (en) 1995-12-31
DD296079A5 (de) 1991-11-21
NZ231872A (en) 1992-03-26
HU901084D0 (en) 1991-09-30
KR910700249A (ko) 1991-03-14
HUT57202A (en) 1991-11-28
SE8804629D0 (sv) 1988-12-22
PT92648B (pt) 1995-09-12
LV10187A (lv) 1994-10-20
PT92648A (pt) 1990-06-29
EP0449940A1 (fr) 1991-10-09
LTIP1726A (en) 1995-07-25
RU2073676C1 (ru) 1997-02-20
FI913035A0 (fi) 1991-06-20
LT3980B (en) 1996-06-25
CA2005986A1 (fr) 1990-06-22

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