ZA935304B - Antiinflamatory indolinyl n-hydroxyurea and n-hydroxamic acid derivatives - Google Patents

Antiinflamatory indolinyl n-hydroxyurea and n-hydroxamic acid derivatives

Info

Publication number
ZA935304B
ZA935304B ZA935304A ZA935304A ZA935304B ZA 935304 B ZA935304 B ZA 935304B ZA 935304 A ZA935304 A ZA 935304A ZA 935304 A ZA935304 A ZA 935304A ZA 935304 B ZA935304 B ZA 935304B
Authority
ZA
South Africa
Prior art keywords
alkyl
aryl
halosubstituted
alkoxy
independently
Prior art date
Application number
ZA935304A
Other languages
English (en)
Inventor
Kafumi Ikeda
Rodney W Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA935304B publication Critical patent/ZA935304B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA935304A 1992-07-23 1993-07-22 Antiinflamatory indolinyl n-hydroxyurea and n-hydroxamic acid derivatives ZA935304B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4197242A JP2661841B2 (ja) 1992-07-23 1992-07-23 インドリン誘導体

Publications (1)

Publication Number Publication Date
ZA935304B true ZA935304B (en) 1995-01-23

Family

ID=16371216

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA935304A ZA935304B (en) 1992-07-23 1993-07-22 Antiinflamatory indolinyl n-hydroxyurea and n-hydroxamic acid derivatives

Country Status (24)

Country Link
EP (1) EP0651743B1 (de)
JP (1) JP2661841B2 (de)
KR (1) KR950702533A (de)
CN (1) CN1085894A (de)
AT (1) ATE161250T1 (de)
AU (1) AU675654B2 (de)
BR (1) BR9306762A (de)
CA (1) CA2140344C (de)
CZ (1) CZ15995A3 (de)
DE (1) DE69315841T2 (de)
DK (1) DK0651743T3 (de)
ES (1) ES2110101T3 (de)
FI (1) FI104068B (de)
GR (1) GR3025809T3 (de)
HU (1) HUT70182A (de)
IL (1) IL106359A0 (de)
MX (1) MX9304441A (de)
NZ (1) NZ253881A (de)
PL (1) PL307229A1 (de)
SK (1) SK8695A3 (de)
TW (1) TW227556B (de)
WO (1) WO1994002459A1 (de)
YU (1) YU50893A (de)
ZA (1) ZA935304B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992006573A1 (en) * 1990-10-02 1992-04-16 Stat-Tech International Corporation Electric charge discharge and dissipation device
WO1998015530A1 (en) * 1996-10-08 1998-04-16 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
US5952322A (en) * 1996-12-05 1999-09-14 Pfizer Inc. Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors
WO2000003703A1 (en) * 1998-07-17 2000-01-27 Fuji Yakuhin Kogyo Kabushiki Kaisha Novel remedies for allergic diseases
EP1283199A4 (de) * 2000-05-16 2003-12-17 Takeda Chemical Industries Ltd Antagonisten des melanin-konzentrierenden hormons
UA95084C2 (en) * 2005-11-04 2011-07-11 Амира Фармасутикалз, Инк. 5-lipoxygenase-activating protein (flap) inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2059408T3 (es) * 1987-02-10 1994-11-16 Abbott Lab Un proceso para la preparacion de un compuesto.
IL95584A (en) * 1989-09-07 1995-03-15 Abbott Lab Indole-, benzoporene- and benzothiophene compounds including lipoxygenase-inhibiting compounds and pharmaceutical compounds containing them
KR900016822A (ko) * 1990-04-20 1990-11-14 하라 레이노스께 슬라이드 프로젝터
US5132319A (en) * 1991-03-28 1992-07-21 Merck Frosst Canada, Inc. 1-(hydroxylaminoalkyl) indole derivatives as inhibitors of leukotriene biosynthesis

Also Published As

Publication number Publication date
JP2661841B2 (ja) 1997-10-08
AU675654B2 (en) 1997-02-13
SK8695A3 (en) 1995-07-11
ATE161250T1 (de) 1998-01-15
DE69315841T2 (de) 1998-04-09
DE69315841D1 (de) 1998-01-29
EP0651743A1 (de) 1995-05-10
FI933307L (fi) 1994-01-24
BR9306762A (pt) 1998-12-08
AU4529193A (en) 1994-02-14
TW227556B (de) 1994-08-01
PL307229A1 (en) 1995-05-15
EP0651743B1 (de) 1997-12-17
NZ253881A (en) 1996-01-26
FI933307A0 (fi) 1993-07-22
MX9304441A (es) 1994-07-29
CA2140344C (en) 1997-08-26
CN1085894A (zh) 1994-04-27
HUT70182A (en) 1995-09-28
FI104068B1 (fi) 1999-11-15
CA2140344A1 (en) 1994-02-03
GR3025809T3 (en) 1998-03-31
YU50893A (sh) 1996-07-24
DK0651743T3 (da) 1998-02-02
JPH0641068A (ja) 1994-02-15
FI104068B (fi) 1999-11-15
CZ15995A3 (en) 1995-09-13
WO1994002459A1 (en) 1994-02-03
IL106359A0 (en) 1993-11-15
ES2110101T3 (es) 1998-02-01
KR950702533A (ko) 1995-07-29
HU9302126D0 (en) 1993-10-28

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