ZA959215B - Substituted tetracyclic azepine derivatives - Google Patents

Substituted tetracyclic azepine derivatives

Info

Publication number: ZA959215B
Authority: ZA; South Africa
Prior art keywords: substituted tetracyclic; azepine derivatives; tetracyclic azepine; derivatives; substituted
Prior art date: 1994-11-02

Application number

ZA959215A

Other languages

English (en)

Inventor

Victor Karel Sipido

Francisco Javi Fernandez-Gadea

Jose Ignacio Andres-Gil

Theo Frans Meert

Pilar Gil-Lopetegui

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-02

Filing date

1995-10-31

Publication date

1997-04-30

1995-10-31 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1997-04-30 Publication of ZA959215B publication Critical patent/ZA959215B/xx

Links

150000001538 azepines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Anesthesiology (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA959215A 1994-11-02 1995-10-31 Substituted tetracyclic azepine derivatives ZA959215B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP94203178		1994-11-02

Publications (1)

Publication Number	Publication Date
ZA959215B true ZA959215B (en)	1997-04-30

Family

ID=8217337

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA959215A ZA959215B (en)	1994-11-02	1995-10-31	Substituted tetracyclic azepine derivatives

Country Status (30)

Country	Link
US (1)	US5552399A (de)
EP (1)	EP0789701B1 (de)
JP (1)	JP3818541B2 (de)
KR (1)	KR100392060B1 (de)
CN (1)	CN1085667C (de)
AR (1)	AR002238A1 (de)
AT (1)	ATE199087T1 (de)
AU (1)	AU704285B2 (de)
BR (1)	BR9509552A (de)
CA (1)	CA2203661A1 (de)
CZ (1)	CZ286945B6 (de)
DE (1)	DE69520070T2 (de)
DK (1)	DK0789701T3 (de)
ES (1)	ES2155898T3 (de)
FI (1)	FI113050B (de)
GR (1)	GR3035680T3 (de)
HR (1)	HRP950537A2 (de)
HU (1)	HUT77408A (de)
IL (1)	IL115819A (de)
MY (1)	MY113325A (de)
NO (1)	NO308035B1 (de)
NZ (1)	NZ295656A (de)
PL (1)	PL183686B1 (de)
PT (1)	PT789701E (de)
RU (1)	RU2163240C2 (de)
SI (1)	SI0789701T1 (de)
TR (1)	TR199501356A2 (de)
TW (1)	TW349950B (de)
WO (1)	WO1996014320A1 (de)
ZA (1)	ZA959215B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0892804B1 (de) *	1996-04-12	2002-08-28	Janssen Pharmaceutica N.V.	Isoxazolidine derivate
UA52778C2 (uk)	1997-10-10	2003-01-15	Янссен Фармацевтика Н.В.	Галогенозаміщені тетрациклічні похідні тетрагідрофурану, спосіб їх отримання та композиція на їх основі
HRP20020305A8 (en)	2002-04-10	2009-03-31	GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o.	2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
HRP20030885A2 (en) *	2003-11-03	2005-08-31	Pliva-Istra�iva�ki institut d.o.o.	USE OF 2-THIA-DIBENZO[e,h]AZULENES FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYYTEM DISEASES AND DISORDERS
HRP20030953A2 (en) *	2003-11-21	2005-10-31	Pliva-Istra�iva�ki institut d.o.o.	PREPARATION OF 1-AZA-2-OXA-DIBENZO[e,h]AZULENES AND THEIR USE FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS
US20110086086A1 (en) *	2005-07-26	2011-04-14	Pfizer Inc	Transdermal system for varenicline
EP3651751A4 (de)	2017-07-13	2021-03-31	Tonix Pharmaceuticals Holding Corp.	Cyclobenzaprin-analoga und amitryptilen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT338799B (de) *	1974-03-02	1977-09-12	Boehringer Sohn Ingelheim	Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze
NL7414038A (nl) *	1974-10-28	1976-05-03	Akzo Nv	Nieuwe tetracyclische pyrrolidino derivaten.
DE2647114A1 (de) *	1975-10-21	1977-05-05	Hans Fickler	Vorrichtung zur erzeugung einer laengsbewegung
JPS5572177A (en) *	1978-11-27	1980-05-30	Shionogi & Co Ltd	4,1-benzoxazepine or 4,1-benzothiazepine
CA2026925A1 (en) *	1989-10-05	1991-04-06	Hiroshi Fukumi	Tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
US5512563A (en) *	1993-07-29	1996-04-30	American Cyanamid Company	Tricyclic benzazepine vasopressin antagonists

1995
- 1995-05-31 US US08/457,968 patent/US5552399A/en not_active Expired - Fee Related
- 1995-10-20 TW TW084111063A patent/TW349950B/zh active
- 1995-10-25 NZ NZ295656A patent/NZ295656A/xx unknown
- 1995-10-25 AT AT95937006T patent/ATE199087T1/de not_active IP Right Cessation
- 1995-10-25 KR KR1019970702800A patent/KR100392060B1/ko not_active Expired - Fee Related
- 1995-10-25 AU AU39249/95A patent/AU704285B2/en not_active Ceased
- 1995-10-25 EP EP95937006A patent/EP0789701B1/de not_active Expired - Lifetime
- 1995-10-25 SI SI9530482T patent/SI0789701T1/xx unknown
- 1995-10-25 PT PT95937006T patent/PT789701E/pt unknown
- 1995-10-25 RU RU97108691/04A patent/RU2163240C2/ru not_active IP Right Cessation
- 1995-10-25 PL PL95319939A patent/PL183686B1/pl not_active IP Right Cessation
- 1995-10-25 WO PCT/EP1995/004196 patent/WO1996014320A1/en not_active Ceased
- 1995-10-25 BR BR9509552A patent/BR9509552A/pt not_active IP Right Cessation
- 1995-10-25 DE DE69520070T patent/DE69520070T2/de not_active Expired - Fee Related
- 1995-10-25 ES ES95937006T patent/ES2155898T3/es not_active Expired - Lifetime
- 1995-10-25 JP JP51500996A patent/JP3818541B2/ja not_active Expired - Fee Related
- 1995-10-25 DK DK95937006T patent/DK0789701T3/da active
- 1995-10-25 CA CA002203661A patent/CA2203661A1/en not_active Abandoned
- 1995-10-25 CN CN95195969A patent/CN1085667C/zh not_active Expired - Fee Related
- 1995-10-25 HU HU9702298A patent/HUT77408A/hu unknown
- 1995-10-25 CZ CZ19971323A patent/CZ286945B6/cs not_active IP Right Cessation
- 1995-10-31 IL IL11581995A patent/IL115819A/en not_active IP Right Cessation
- 1995-10-31 HR HR08/457,968A patent/HRP950537A2/hr not_active Application Discontinuation
- 1995-10-31 ZA ZA959215A patent/ZA959215B/xx unknown
- 1995-11-01 AR ARP950100010A patent/AR002238A1/es unknown
- 1995-11-02 MY MYPI95003312A patent/MY113325A/en unknown
- 1995-11-02 TR TR95/01356A patent/TR199501356A2/xx unknown
1997
- 1997-04-30 NO NO972017A patent/NO308035B1/no unknown
- 1997-04-30 FI FI971854A patent/FI113050B/fi not_active IP Right Cessation
2001
- 2001-03-30 GR GR20010400530T patent/GR3035680T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL115819A0 (en)	1996-01-19
HRP950537A2 (en)	1997-08-31
NO972017D0 (no)	1997-04-30
RU2163240C2 (ru)	2001-02-20
CN1162313A (zh)	1997-10-15
NO972017L (no)	1997-04-30
EP0789701A1 (de)	1997-08-20
ATE199087T1 (de)	2001-02-15
MY113325A (en)	2002-01-31
PT789701E (pt)	2001-07-31
CZ286945B6 (en)	2000-08-16
HUT77408A (hu)	1998-04-28
IL115819A (en)	1998-10-30
PL319939A1 (en)	1997-09-01
TR199501356A2 (tr)	1996-06-21
AR002238A1 (es)	1998-03-11
MX9703255A (es)	1997-07-31
NO308035B1 (no)	2000-07-10
CZ132397A3 (cs)	1998-01-14
JPH10508308A (ja)	1998-08-18
BR9509552A (pt)	1997-09-16
SI0789701T1 (en)	2001-08-31
GR3035680T3 (en)	2001-06-29
PL183686B1 (pl)	2002-06-28
ES2155898T3 (es)	2001-06-01
KR100392060B1 (ko)	2003-11-28
AU3924995A (en)	1996-05-31
JP3818541B2 (ja)	2006-09-06
WO1996014320A1 (en)	1996-05-17
NZ295656A (en)	1998-10-28
CA2203661A1 (en)	1996-05-17
FI971854A0 (fi)	1997-04-30
EP0789701B1 (de)	2001-02-07
AU704285B2 (en)	1999-04-15
CN1085667C (zh)	2002-05-29
US5552399A (en)	1996-09-03
DE69520070D1 (de)	2001-03-15
TW349950B (en)	1999-01-11
DE69520070T2 (de)	2001-09-13
FI113050B (fi)	2004-02-27
DK0789701T3 (da)	2001-06-18
FI971854A7 (fi)	1997-04-30

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HUP9900790A3 (en)	2001-11-28	Imidazoquinazoline derivatives
EP0519307A3 (en)	1993-04-21	Tetracyclic imidazodiazepines
GB9511077D0 (en)	1995-07-26	17B-Substituted-6-azasteroid derivatives
GB9015879D0 (en)	1990-09-05	Benzodiazepine derivatives
ZA9510027B (en)	1996-06-03	Pyrrole derivatives
PL332896A1 (en)	1999-10-25	Substituted tricyclic compounds
ZA984560B (en)	1998-11-30	Ergoline derivatives
EP0692482A3 (de)	1996-02-28	1-Pyridyltetrazolinon-Derivate
HU9300488D0 (en)	1993-05-28	Tricyclic benzodiazepine derivatives
ZA965318B (en)	1997-01-24	Camptothecin beta-hydrolactone compounds
ZA939291B (en)	1995-06-09	Diazepine derivatives
HU9501693D0 (en)	1995-08-28	Benzazepinone derivatives
ZA959215B (en)	1997-04-30	Substituted tetracyclic azepine derivatives
GB9511365D0 (en)	1995-08-02	Pyridazino-indole derivatives
LTIP657A (en)	1994-05-15	Benzodiazepine derivatives
ZA902148B (en)	1990-12-28	Benzazepine derivatives
GB9317692D0 (en)	1993-10-13	Benzodiazepine derivatives
GB9320113D0 (en)	1993-11-17	Tricyclic derivatives
HU9500007D0 (en)	1995-03-28	Tricyclic cepheme derivatives
AU1541195A (en)	1995-08-21	Antitumour tetracyclic compounds
PL318145A1 (en)	1997-05-12	Tetracyclic triterpenes
GB2287463B (en)	1997-12-03	Bis-anthracycline derivatives
GB2291425B (en)	1998-07-01	7-Diazo-beta-lactam derivatives
GB9525365D0 (en)	1996-02-14	Benzazepine derivatives