AR080331A2 - Proteina nef-tat-his o nef-mutada tat-his, metodo para prepararla y metodo para producir una vacuna que comprende dicha proteina - Google Patents

Proteina nef-tat-his o nef-mutada tat-his, metodo para prepararla y metodo para producir una vacuna que comprende dicha proteina

Info

Publication number
AR080331A2
AR080331A2 ARP110100606A ARP110100606A AR080331A2 AR 080331 A2 AR080331 A2 AR 080331A2 AR P110100606 A ARP110100606 A AR P110100606A AR P110100606 A ARP110100606 A AR P110100606A AR 080331 A2 AR080331 A2 AR 080331A2
Authority
AR
Argentina
Prior art keywords
protein
nef
tat
derivative
hiv
Prior art date
Application number
ARP110100606A
Other languages
English (en)
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10819735&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR080331(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Publication of AR080331A2 publication Critical patent/AR080331A2/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16311Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A) una proteína Tat de VIH o un derivado de ella, enlazada o bien (i) a un partícipe en la fusion o (ii) a una proteína Net de VIH o un derivado de ella; o (b) a una proteína Net de VIH o un derivado de ella, enlazada o bien (i) a un partícipe en la fusion o (ii) a una proteína Tat de VIH o un derivado de ella; o (c) a una proteína Nef de VIH o un derivado de ella, enlazada a una proteína Tat de VIH o un derivado de ella, y un participe en la fusion. Además un ácido nucleico que codifica dicha proteína y una célula hospedante, tal como Pichia pastoris, transformada con el ácido nucleico antes mencionado.
ARP110100606A 1997-09-26 2011-02-28 Proteina nef-tat-his o nef-mutada tat-his, metodo para prepararla y metodo para producir una vacuna que comprende dicha proteina AR080331A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9720585.0A GB9720585D0 (en) 1997-09-26 1997-09-26 Vaccine

Publications (1)

Publication Number Publication Date
AR080331A2 true AR080331A2 (es) 2012-03-28

Family

ID=10819735

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP980104779A AR017147A1 (es) 1997-09-26 1998-09-24 Composicion de vacuna de proteina que comprende una proteina nef de vih, dicha proteina, metodo para prepararla y metodo para producir dicha vacuna
ARP110100606A AR080331A2 (es) 1997-09-26 2011-02-28 Proteina nef-tat-his o nef-mutada tat-his, metodo para prepararla y metodo para producir una vacuna que comprende dicha proteina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP980104779A AR017147A1 (es) 1997-09-26 1998-09-24 Composicion de vacuna de proteina que comprende una proteina nef de vih, dicha proteina, metodo para prepararla y metodo para producir dicha vacuna

Country Status (27)

Country Link
EP (1) EP1015596B2 (es)
JP (2) JP2001518300A (es)
KR (1) KR100554487B1 (es)
CN (1) CN1188519C (es)
AR (2) AR017147A1 (es)
AT (1) ATE338128T1 (es)
AU (1) AU746564B2 (es)
BR (1) BR9812547A (es)
CA (1) CA2305013C (es)
CO (1) CO4810339A1 (es)
CZ (1) CZ302878B6 (es)
DE (1) DE69835756T3 (es)
DK (1) DK1015596T4 (es)
ES (1) ES2272012T5 (es)
GB (1) GB9720585D0 (es)
HU (1) HUP0004896A3 (es)
IL (1) IL135102A0 (es)
NO (2) NO328824B1 (es)
NZ (1) NZ503482A (es)
PL (1) PL195243B1 (es)
PT (1) PT1015596E (es)
SA (1) SA98190877B1 (es)
SI (1) SI1015596T2 (es)
TR (1) TR200000864T2 (es)
TW (1) TW499436B (es)
WO (1) WO1999016884A1 (es)
ZA (1) ZA988789B (es)

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WO2001000232A2 (en) * 1999-06-29 2001-01-04 Smithkline Beecham Biologicals S.A. Use of cpg as an adjuvant for hiv vaccine
GB0000891D0 (en) 2000-01-14 2000-03-08 Allergy Therapeutics Ltd Formulation
OA12168A (en) * 2000-01-31 2006-05-08 Smithkline Beecham Biolog Vaccine for the prophylactic or therapeutic immunization against HIV.
US6472176B2 (en) 2000-12-14 2002-10-29 Genvec, Inc. Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof
GB0110431D0 (en) * 2001-04-27 2001-06-20 Glaxosmithkline Biolog Sa Novel compounds
EP1279404A1 (en) * 2001-07-26 2003-01-29 Istituto Superiore di Sanità Use of HIV-1 tat, fragments or derivatives thereof, to target or to activate antigen-presenting cells, to deliver cargo molecules for vaccination or to treat other diseases
GB0118367D0 (en) * 2001-07-27 2001-09-19 Glaxosmithkline Biolog Sa Novel use
HU230364B1 (hu) 2001-11-21 2016-03-29 The Trustees Of The University Of Pennsylvania Simian adenovírus nukleinsav és aminosav-szekvencia, azt tartalmazó vektorok, és eljárások annak alkalmazására
EP1944043A1 (en) 2001-11-21 2008-07-16 The Trustees of the University of Pennsylvania Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
KR100466382B1 (ko) * 2002-01-08 2005-01-14 주식회사 엘지생명과학 인간 면역 결핍 바이러스-1, -2 타입의 단백질이 융합된 재조합 콤보 단백질, 이의 생산방법, 이를 포함하는 벡터, 형질전환된 대장균 및 진단키트
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TW200613554A (en) 2004-06-17 2006-05-01 Wyeth Corp Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV
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GB0507003D0 (en) * 2005-04-06 2005-05-11 Molmed Spa Therapeutic
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WO2009105084A2 (en) 2007-11-28 2009-08-27 The Trustees Of The University Of Pennsylvania Simian subfamily c adenoviruses sadv-40, -31, and-34 and uses thereof
EP2250255A2 (en) 2008-03-04 2010-11-17 The Trustees of the University of Pennsylvania Simian adenoviruses sadv-36,-42.1, -42.2, and -44 and uses thereof
US8986702B2 (en) 2008-05-16 2015-03-24 Taiga Biotechnologies, Inc. Antibodies and processes for preparing the same
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Also Published As

Publication number Publication date
ATE338128T1 (de) 2006-09-15
TR200000864T2 (tr) 2000-08-21
AU746564B2 (en) 2002-05-02
HK1030431A1 (en) 2001-05-04
ZA988789B (en) 2000-03-29
WO1999016884A1 (en) 1999-04-08
PL339432A1 (en) 2000-12-18
KR20010024287A (ko) 2001-03-26
NZ503482A (en) 2001-09-28
NO328824B1 (no) 2010-05-25
AU1025599A (en) 1999-04-23
CO4810339A1 (es) 1999-06-30
SI1015596T1 (sl) 2007-02-28
EP1015596A1 (en) 2000-07-05
CZ20001091A3 (cs) 2000-09-13
CZ302878B6 (cs) 2012-01-04
DE69835756T3 (de) 2010-09-30
JP2001518300A (ja) 2001-10-16
SA98190877B1 (ar) 2006-09-10
CN1188519C (zh) 2005-02-09
NO20001508L (no) 2000-05-18
AR017147A1 (es) 2001-08-22
PL195243B1 (pl) 2007-08-31
NO20001508D0 (no) 2000-03-23
PT1015596E (pt) 2006-12-29
CA2305013C (en) 2008-04-08
DK1015596T4 (da) 2010-07-12
BR9812547A (pt) 2000-07-25
ES2272012T3 (es) 2007-04-16
NO20076467L (no) 2000-05-18
HUP0004896A1 (hu) 2001-04-28
CN1279718A (zh) 2001-01-10
DE69835756T2 (de) 2007-09-13
EP1015596B1 (en) 2006-08-30
KR100554487B1 (ko) 2006-03-03
TW499436B (en) 2002-08-21
HUP0004896A3 (en) 2003-05-28
ES2272012T5 (es) 2010-07-06
GB9720585D0 (en) 1997-11-26
DE69835756D1 (de) 2006-10-12
IL135102A0 (en) 2001-05-20
CA2305013A1 (en) 1999-04-08
JP2009213492A (ja) 2009-09-24
EP1015596B2 (en) 2010-04-14
SI1015596T2 (sl) 2010-07-30
DK1015596T3 (da) 2007-01-02

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