NO20076467L - Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteiner - Google Patents
Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteinerInfo
- Publication number
- NO20076467L NO20076467L NO20076467A NO20076467A NO20076467L NO 20076467 L NO20076467 L NO 20076467L NO 20076467 A NO20076467 A NO 20076467A NO 20076467 A NO20076467 A NO 20076467A NO 20076467 L NO20076467 L NO 20076467L
- Authority
- NO
- Norway
- Prior art keywords
- hiv
- derivative
- tat
- proteins
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Oppfinnelsen tilveiebringer (a) et HIV-Tat-protein eller derivat derav koblet til enten (i) en fusjonspartner eller (ii) et HTV Nef-protein eller derivat derav; eller (b) et HTV Nef-protein eller derivat derav koblet til enten (i) en fusjonspartner eller (ii) et HIV-Tat-protein eller derivat derav; eller (c) et HTV-Nef-protein eller derivat derav koblet til et HIV-Tat-protein eller derivat derav og en fusjonspartner. Oppfinnelsen tilveiebringer videre en nukleinsyre som koder for et slikt protein og en vertscelle, slik som Pichia Pastoris, transformert med den før nevnte nukleinsyren.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9720585.0A GB9720585D0 (en) | 1997-09-26 | 1997-09-26 | Vaccine |
| PCT/EP1998/006040 WO1999016884A1 (en) | 1997-09-26 | 1998-09-17 | Fusion proteins comprising hiv-1 tat and/or nef proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076467L true NO20076467L (no) | 2000-05-18 |
Family
ID=10819735
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20001508A NO328824B1 (no) | 1997-09-26 | 2000-03-23 | Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert. |
| NO20076467A NO20076467L (no) | 1997-09-26 | 2007-12-14 | Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteiner |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20001508A NO328824B1 (no) | 1997-09-26 | 2000-03-23 | Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert. |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1015596B2 (no) |
| JP (2) | JP2001518300A (no) |
| KR (1) | KR100554487B1 (no) |
| CN (1) | CN1188519C (no) |
| AR (2) | AR017147A1 (no) |
| AT (1) | ATE338128T1 (no) |
| AU (1) | AU746564B2 (no) |
| BR (1) | BR9812547A (no) |
| CA (1) | CA2305013C (no) |
| CO (1) | CO4810339A1 (no) |
| CZ (1) | CZ302878B6 (no) |
| DE (1) | DE69835756T3 (no) |
| DK (1) | DK1015596T4 (no) |
| ES (1) | ES2272012T5 (no) |
| GB (1) | GB9720585D0 (no) |
| HU (1) | HUP0004896A3 (no) |
| IL (1) | IL135102A0 (no) |
| NO (2) | NO328824B1 (no) |
| NZ (1) | NZ503482A (no) |
| PL (1) | PL195243B1 (no) |
| PT (1) | PT1015596E (no) |
| SA (1) | SA98190877B1 (no) |
| SI (1) | SI1015596T2 (no) |
| TR (1) | TR200000864T2 (no) |
| TW (1) | TW499436B (no) |
| WO (1) | WO1999016884A1 (no) |
| ZA (1) | ZA988789B (no) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| GB9720585D0 (en) * | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
| GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| EP1156825A2 (en) * | 1999-02-25 | 2001-11-28 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Immunogens comprising a peptide and a carrier derived from h.influenzae protein d |
| EP1175436B1 (en) * | 1999-04-12 | 2006-10-11 | Heart Biosystems GmbH | Transiently immortalized cells for use in gene therapy |
| AU5821000A (en) * | 1999-06-29 | 2001-01-31 | Smithkline Beecham Biologicals (Sa) | Vaccine |
| GB0000891D0 (en) | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| BR0107972A (pt) * | 2000-01-31 | 2002-11-05 | Smithkline Beecham Biologicals | Uso de uma proteìna ou polinucleotìdeo tat do hiv, nef do hiv, ou tat do hiv ligado(a) a uma proteìna ou polinucleotìdeo nef do hiv (nef-tat), e de uma proteìna ou polinucleotìdeo gp120 do hiv, método para imunizar um ser humano contra o hiv, e, composição de vacina para o uso humano |
| US6472176B2 (en) | 2000-12-14 | 2002-10-29 | Genvec, Inc. | Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof |
| GB0110431D0 (en) * | 2001-04-27 | 2001-06-20 | Glaxosmithkline Biolog Sa | Novel compounds |
| EP1279404A1 (en) * | 2001-07-26 | 2003-01-29 | Istituto Superiore di Sanità | Use of HIV-1 tat, fragments or derivatives thereof, to target or to activate antigen-presenting cells, to deliver cargo molecules for vaccination or to treat other diseases |
| GB0118367D0 (en) * | 2001-07-27 | 2001-09-19 | Glaxosmithkline Biolog Sa | Novel use |
| AU2002365366B2 (en) | 2001-11-21 | 2007-05-10 | The Trustees Of The University Of Pennsylvania | Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use |
| EP1944043A1 (en) | 2001-11-21 | 2008-07-16 | The Trustees of the University of Pennsylvania | Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use |
| KR100466382B1 (ko) * | 2002-01-08 | 2005-01-14 | 주식회사 엘지생명과학 | 인간 면역 결핍 바이러스-1, -2 타입의 단백질이 융합된 재조합 콤보 단백질, 이의 생산방법, 이를 포함하는 벡터, 형질전환된 대장균 및 진단키트 |
| GB0206359D0 (en) | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| GB0206360D0 (en) | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| UA82998C2 (ru) | 2002-05-16 | 2008-06-10 | Бавариан Нордик А/С | Экспрессия генов в модифицированном вирусе коровьей оспы ankara с использованием коровьего поксвирусного промотора аті |
| GB0225788D0 (en) | 2002-11-05 | 2002-12-11 | Glaxo Group Ltd | Vaccine |
| US7927580B2 (en) | 2004-03-16 | 2011-04-19 | Nanirx, Inc. | Tat-based immunomodulatory compositions and methods of their discovery and use |
| TW200613554A (en) | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
| GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
| GB0507003D0 (en) * | 2005-04-06 | 2005-05-11 | Molmed Spa | Therapeutic |
| IL296832A (en) * | 2005-10-18 | 2022-11-01 | Nat Jewish Health | Process of preparing red blood cells using conditionally immortalized long-term hematopoietic stem cells and erythropoietin |
| CN101883858B (zh) | 2007-11-28 | 2015-07-22 | 宾夕法尼亚大学托管会 | 猿猴亚家族E腺病毒SAdV-39、-25.2、-26、-30、-37和-38及其应用 |
| CN102131920B (zh) | 2007-11-28 | 2013-11-06 | 宾夕法尼亚大学托管会 | 猿猴亚家族C腺病毒SAdV-40、-31和-34及其应用 |
| JP5661476B2 (ja) | 2008-03-04 | 2015-01-28 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | サルアデノウイルスSAdV−36、−42.1、−42.2および−44ならびにそれらの用途 |
| SG10201803982TA (en) | 2008-05-16 | 2018-07-30 | Taiga Biotechnologies Inc | Antibodies and processes for preparing the same |
| SG193145A1 (en) | 2008-07-21 | 2013-09-30 | Taiga Biotechnologies Inc | Differentiated anucleated cells and method for preparing the same |
| DK3339321T3 (da) | 2008-08-28 | 2021-06-21 | Taiga Biotechnologies Inc | Modulatorer af myc, fremgangsmåder til anvendelse af samme og fremgangsmåder til at identificere stoffer der modulerer myc |
| WO2010051367A1 (en) | 2008-10-31 | 2010-05-06 | The Trustees Of The University Of Pennsylvania | Simian adenoviruses sadv-43, -45,-48,-49, and -50 and uses thereof |
| EP2411043B1 (en) | 2009-03-23 | 2013-07-31 | PIN Pharma, Inc. | Treatment of cancer with immunostimulatory hiv tat derivative polypeptides |
| CA2762203A1 (en) | 2009-05-29 | 2010-12-02 | Soumitra Roy | Simian adenovirus 41 and uses thereof |
| AU2011332025B2 (en) | 2010-11-23 | 2015-06-25 | The Trustees Of The University Of Pennsylvania | Subfamily E simian adenoviruses A1321, A1325, A1295, A1309 and A1322 and uses thereof |
| US9110059B2 (en) * | 2011-03-15 | 2015-08-18 | Industry-Academic Cooperation Foundation, Yonsei University | Bio-pin |
| SG11201407343XA (en) | 2012-05-18 | 2014-12-30 | Univ Pennsylvania | Subfamily e simian adenoviruses a1302, a1320, a1331 and a1337 and uses thereof |
| WO2014012090A1 (en) | 2012-07-13 | 2014-01-16 | The Broad Institute, Inc. | Molecular sleds comprising a positively-charged amino acid sequence and a molecular cargo and uses thereof |
| US9789135B2 (en) | 2012-07-20 | 2017-10-17 | Taiga Biotechnologies, Inc. | Enhanced reconstitution and autoreconstitution of the hematopoietic compartment |
| US9365825B2 (en) | 2013-03-11 | 2016-06-14 | Taiga Biotechnologies, Inc. | Expansion of adult stem cells in vitro |
| US10272115B2 (en) | 2013-03-11 | 2019-04-30 | Taiga Biotechnologies, Inc. | Production and use of red blood cells |
| CN105705164A (zh) | 2013-10-04 | 2016-06-22 | 品诺制药公司 | 用于癌症治疗的免疫刺激性hiv tat衍生多肽 |
| ES2833230T3 (es) | 2014-05-13 | 2021-06-14 | Univ Pennsylvania | Composiciones que comprenden AVV que expresan construcciones y usos de doble anticuerpo del mismo |
| US11207421B2 (en) | 2015-04-16 | 2021-12-28 | The Research Foundation For The State University Of New York | Nanostructures comprising cobalt porphyrin-phospholipid conjugates and polyhistidine-tags |
| EP3283056B3 (en) * | 2015-04-16 | 2022-04-06 | The Research Foundation For The State University Of New York University at Buffalo | Nanostructures comprising cobalt porphyrin-phospholipid conjugates and polyhistidine-tags |
| EP3548425B1 (en) | 2016-12-02 | 2023-03-29 | Taiga Biotechnologies, Inc. | Nanoparticle formulations |
| US10149898B2 (en) | 2017-08-03 | 2018-12-11 | Taiga Biotechnologies, Inc. | Methods and compositions for the treatment of melanoma |
| CN113874033A (zh) | 2019-04-08 | 2021-12-31 | 泰加生物工艺学公司 | 用于冷冻保存免疫细胞的组合物和方法 |
| EP3969041A4 (en) | 2019-05-14 | 2023-05-10 | Taiga Biotechnologies, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF T-CELL DEPLETION |
| AU2022264509A1 (en) | 2021-04-27 | 2023-12-14 | Generation Bio Co. | Non-viral dna vectors expressing therapeutic antibodies and uses thereof |
| CN119072330A (zh) | 2022-03-14 | 2024-12-03 | 世代生物公司 | 异源初免加强疫苗组合物和使用方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9003010D0 (en) * | 1990-02-09 | 1990-04-04 | Glaxo Group Ltd | Gene expression in yeast cells |
| JPH07502646A (ja) * | 1991-10-21 | 1995-03-23 | メディミューン,インコーポレーテッド | リポタンパク質の分泌シグナルをコード化するdnaを含む細菌発現ベクター |
| ES2123062T3 (es) * | 1992-08-21 | 1999-01-01 | Biogen Inc | Polipeptidos de transporte derivados de la proteina tat. |
| HU219767B (hu) * | 1993-01-26 | 2001-07-30 | Leslie R. Coney | Készítmények és eljárások genetikai anyag sejtbe történő beviteléhez |
| ATE196255T1 (de) * | 1995-03-08 | 2000-09-15 | Neovacs | Von einem retroviralen regulationsprotein abstammende, detoxifierte immunogene, dagegen gerichtete antikörper, verfahren zur deren herstellung und diese immunogene oder antikörper enthaltende, pharmazeutische zusammensetzungen. |
| GB9720585D0 (en) * | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
-
1997
- 1997-09-26 GB GBGB9720585.0A patent/GB9720585D0/en not_active Ceased
-
1998
- 1998-09-17 PT PT98952625T patent/PT1015596E/pt unknown
- 1998-09-17 ES ES98952625T patent/ES2272012T5/es not_active Expired - Lifetime
- 1998-09-17 AT AT98952625T patent/ATE338128T1/de active
- 1998-09-17 NZ NZ503482A patent/NZ503482A/en not_active IP Right Cessation
- 1998-09-17 SI SI9830860T patent/SI1015596T2/sl unknown
- 1998-09-17 CN CNB988114321A patent/CN1188519C/zh not_active Expired - Fee Related
- 1998-09-17 HU HU0004896A patent/HUP0004896A3/hu unknown
- 1998-09-17 PL PL98339432A patent/PL195243B1/pl not_active IP Right Cessation
- 1998-09-17 DK DK98952625.6T patent/DK1015596T4/da active
- 1998-09-17 EP EP98952625A patent/EP1015596B2/en not_active Expired - Lifetime
- 1998-09-17 AU AU10255/99A patent/AU746564B2/en not_active Ceased
- 1998-09-17 KR KR1020007003180A patent/KR100554487B1/ko not_active Expired - Fee Related
- 1998-09-17 DE DE69835756T patent/DE69835756T3/de not_active Expired - Lifetime
- 1998-09-17 JP JP2000513953A patent/JP2001518300A/ja not_active Withdrawn
- 1998-09-17 CA CA002305013A patent/CA2305013C/en not_active Expired - Fee Related
- 1998-09-17 CZ CZ20001091A patent/CZ302878B6/cs not_active IP Right Cessation
- 1998-09-17 BR BR9812547-8A patent/BR9812547A/pt not_active IP Right Cessation
- 1998-09-17 TR TR2000/00864T patent/TR200000864T2/xx unknown
- 1998-09-17 WO PCT/EP1998/006040 patent/WO1999016884A1/en not_active Ceased
- 1998-09-17 IL IL13510298A patent/IL135102A0/xx not_active IP Right Cessation
- 1998-09-24 AR ARP980104779A patent/AR017147A1/es active IP Right Grant
- 1998-09-25 CO CO98056054A patent/CO4810339A1/es unknown
- 1998-09-25 ZA ZA9808789A patent/ZA988789B/xx unknown
- 1998-10-22 TW TW087117493A patent/TW499436B/zh not_active IP Right Cessation
- 1998-12-15 SA SA98190877A patent/SA98190877B1/ar unknown
-
2000
- 2000-03-23 NO NO20001508A patent/NO328824B1/no not_active IP Right Cessation
-
2007
- 2007-12-14 NO NO20076467A patent/NO20076467L/no unknown
-
2009
- 2009-06-30 JP JP2009155916A patent/JP2009213492A/ja active Pending
-
2011
- 2011-02-28 AR ARP110100606A patent/AR080331A2/es not_active Application Discontinuation
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