ATE192654T1 - Verflüssigte darmsubmukosa und ihre verwendung als injizierbares gewebetransplantat - Google Patents

Verflüssigte darmsubmukosa und ihre verwendung als injizierbares gewebetransplantat

Info

Publication number
ATE192654T1
ATE192654T1 AT94900605T AT94900605T ATE192654T1 AT E192654 T1 ATE192654 T1 AT E192654T1 AT 94900605 T AT94900605 T AT 94900605T AT 94900605 T AT94900605 T AT 94900605T AT E192654 T1 ATE192654 T1 AT E192654T1
Authority
AT
Austria
Prior art keywords
intestinal submucosa
tissue
submucosa
intestinal
liquided
Prior art date
Application number
AT94900605T
Other languages
English (en)
Inventor
Peter M Knapp Jr
Stephen F Badylak
Michael Hiles
Sherry Voytik
Robert J Demeter
Original Assignee
Purdue Research Foundation
Methodist Hospital Indiana
Peter M Knapp Jr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation, Methodist Hospital Indiana, Peter M Knapp Jr filed Critical Purdue Research Foundation
Application granted granted Critical
Publication of ATE192654T1 publication Critical patent/ATE192654T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3629—Intestinal tissue, e.g. small intestinal submucosa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/367—Muscle tissue, e.g. sphincter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT94900605T 1992-11-13 1993-11-10 Verflüssigte darmsubmukosa und ihre verwendung als injizierbares gewebetransplantat ATE192654T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/976,156 US5275826A (en) 1992-11-13 1992-11-13 Fluidized intestinal submucosa and its use as an injectable tissue graft
PCT/US1993/010861 WO1994011008A1 (en) 1992-11-13 1993-11-10 Fluidized intestinal submucosa and its use as an injectable tissue graft

Publications (1)

Publication Number Publication Date
ATE192654T1 true ATE192654T1 (de) 2000-05-15

Family

ID=25523793

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94900605T ATE192654T1 (de) 1992-11-13 1993-11-10 Verflüssigte darmsubmukosa und ihre verwendung als injizierbares gewebetransplantat

Country Status (22)

Country Link
US (2) US5275826A (de)
EP (1) EP0671922B1 (de)
JP (1) JP3534408B2 (de)
AT (1) ATE192654T1 (de)
AU (1) AU677974B2 (de)
BR (1) BR9307419A (de)
CA (1) CA2149324C (de)
CZ (1) CZ124095A3 (de)
DE (1) DE69328625T2 (de)
DK (1) DK0671922T3 (de)
ES (1) ES2148309T3 (de)
FI (1) FI952337A0 (de)
GR (1) GR3034144T3 (de)
HU (1) HU218891B (de)
MX (1) MX9307046A (de)
NO (1) NO951881L (de)
NZ (2) NZ258032A (de)
PL (1) PL174426B1 (de)
PT (1) PT671922E (de)
RU (1) RU2148379C1 (de)
SK (1) SK282122B6 (de)
WO (1) WO1994011008A1 (de)

Families Citing this family (367)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5281422A (en) * 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US6653291B1 (en) 1992-11-13 2003-11-25 Purdue Research Foundation Composition and method for production of transformed cells
US5641518A (en) * 1992-11-13 1997-06-24 Purdue Research Foundation Method of repairing bone tissue
US5962427A (en) 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US5763416A (en) 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US6334872B1 (en) * 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
US5942496A (en) 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6074840A (en) 1994-02-18 2000-06-13 The Regents Of The University Of Michigan Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
US20020193338A1 (en) * 1994-02-18 2002-12-19 Goldstein Steven A. In vivo gene transfer methods for wound healing
US6551618B2 (en) * 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US6475232B1 (en) 1996-12-10 2002-11-05 Purdue Research Foundation Stent with reduced thrombogenicity
WO1995029647A2 (en) * 1994-04-29 1995-11-09 Scimed Life Systems, Inc. Stent with collagen
US6485723B1 (en) 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US5695998A (en) * 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
CA2173508A1 (en) * 1995-03-31 1996-10-01 Tooru Yui Medical device and method for producing the same
US5711969A (en) * 1995-04-07 1998-01-27 Purdue Research Foundation Large area submucosal tissue graft constructs
JPH11508151A (ja) * 1995-04-07 1999-07-21 パーデュー・リサーチ・ファウンデーション 膀胱再建方法及び膀胱再建用組織グラフト
US5554389A (en) * 1995-04-07 1996-09-10 Purdue Research Foundation Urinary bladder submucosa derived tissue graft
US5788625A (en) 1996-04-05 1998-08-04 Depuy Orthopaedics, Inc. Method of making reconstructive SIS structure for cartilaginous elements in situ
US5755791A (en) * 1996-04-05 1998-05-26 Purdue Research Foundation Perforated submucosal tissue graft constructs
JP3816534B2 (ja) * 1996-08-16 2006-08-30 チルドレンズ メディカル センター コーポレーション 細胞を接種された組織再建術用膀胱粘膜下組織
US6171344B1 (en) 1996-08-16 2001-01-09 Children's Medical Center Corporation Bladder submucosa seeded with cells for tissue reconstruction
US20010048949A1 (en) * 1996-08-16 2001-12-06 Children's Medical Center Corporation Isolated bladder submucosa for tissue reconstruction
JP5053470B2 (ja) * 1996-08-23 2012-10-17 クック バイオテク インコーポレイティド グラフト・プロテーゼとその材料及び方法
US8716227B2 (en) * 1996-08-23 2014-05-06 Cook Biotech Incorporated Graft prosthesis, materials and methods
US6666892B2 (en) * 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
EP1430899B1 (de) * 1996-09-16 2010-07-07 Purdue Research Foundation Gewebetransplantat aus der Magensubmukosa zur Reparatur neurologischen Gewebes
CA2263898C (en) * 1996-09-16 2009-12-08 Purdue Research Foundation Composition and method for repairing neurological tissue
JP4676580B2 (ja) * 1996-11-05 2011-04-27 パーデュー・リサーチ・ファウンデーション 心筋移植片構成物
DE69720252T2 (de) * 1996-12-10 2003-12-04 Purdue Research Foundation, West Lafayette Gewebetransplantat aus der magensubmukosa
JP2001505807A (ja) * 1996-12-10 2001-05-08 パーデュー・リサーチ・ファウンデーション 人工血管弁
JP4046358B2 (ja) 1996-12-10 2008-02-13 パーデュー・リサーチ・ファウンデーション 粘膜下組織抽出物
CA2274033C (en) 1996-12-10 2010-05-11 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
US6696270B2 (en) 1996-12-10 2004-02-24 Purdue Research Foundation Gastric submucosal tissue as a novel diagnostic tool
AU5696798A (en) 1996-12-10 1998-07-03 Cook Biotech, Inc. Stent grafts containing purified submucosa
EP1300154B1 (de) * 1996-12-10 2005-09-14 Purdue Research Foundation Gewebetransplantat aus der Magensubmukosa
ES2320603T3 (es) 1997-07-30 2009-05-25 Emory University Sistemas de expresion, vectores, adn, proteinas de mineralizacion osea novedosos.
US7923250B2 (en) 1997-07-30 2011-04-12 Warsaw Orthopedic, Inc. Methods of expressing LIM mineralization protein in non-osseous cells
EP1011699B1 (de) * 1997-09-11 2001-12-05 Purdue Research Foundation Durch galactosidase modifiziertes submucosales gewebe
US6485969B1 (en) 1997-12-23 2002-11-26 Purdue Research Foundation Biomaterial derived from follicle basement membranes
US7070607B2 (en) * 1998-01-27 2006-07-04 The Regents Of The University Of California Bioabsorbable polymeric implants and a method of using the same to create occlusions
AU772827B2 (en) * 1998-02-27 2004-05-06 Purdue Research Foundation, Of Office Of Technology Commercialization Purdue University Shape retaining gel compositions
WO1999043786A2 (en) * 1998-02-27 1999-09-02 Purdue Research Foundation Submucosa gel compositions
US6933326B1 (en) * 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
JP5226914B2 (ja) * 1998-06-19 2013-07-03 ライフセル コーポレイション 粒状無細胞組織マトリックス
AU2002300448B2 (en) * 1998-06-19 2005-07-28 Lifecell Corporation Particulate Acellular Tissue Matrix
WO1999067813A1 (en) 1998-06-25 1999-12-29 The Penn State Research Foundation Electrostatic printing of a metallic toner to produce a polycrystalline semiconductor from an amorphous semiconductor
US6458109B1 (en) * 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
US8882850B2 (en) * 1998-12-01 2014-11-11 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
GB2361187A (en) * 1998-12-01 2001-10-17 Purdue Research Foundation Submucosa modulation of mammalian immune response
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
AU1832700A (en) * 1998-12-01 2000-06-19 Mark W. Bleyer Embolization device
CA2319443C (en) * 1998-12-01 2009-09-29 Cook Biotech, Inc. Collagenous biomaterials formed with submucosal tissue
AU761153B2 (en) * 1998-12-01 2003-05-29 Purdue Research Foundation Method for vocal cord reconstruction
DE60041703D1 (de) * 1999-08-06 2009-04-16 Cook Biotech Inc Rohrförmige transplantatkonstruktion
US6555374B1 (en) * 1999-08-19 2003-04-29 Artecel Sciences, Inc. Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
US6824533B2 (en) 2000-11-29 2004-11-30 Hill-Rom Services, Inc. Wound treatment apparatus
WO2001045765A1 (en) 1999-12-22 2001-06-28 Acell, Inc. Tissue regenerative composition
US6579538B1 (en) 1999-12-22 2003-06-17 Acell, Inc. Tissue regenerative compositions for cardiac applications, method of making, and method of use thereof
US6576265B1 (en) * 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
US20040043006A1 (en) * 2002-08-27 2004-03-04 Badylak Stephen F. Tissue regenerative composition
US6689161B2 (en) 2000-04-28 2004-02-10 Baylor College Of Medicine Decellularized vascular prostheses resistant to thrombus occlusion and immunologic rejection
US20010043943A1 (en) * 2000-05-22 2001-11-22 Coffey Arthur C. Combination SIS and vacuum bandage and method
US6435190B1 (en) * 2000-06-14 2002-08-20 Syde A. Taheri Autogenous cell patch cardio myoplasty and advanced muscle graft implantation system
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US6638312B2 (en) * 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US20040167244A1 (en) * 2000-08-18 2004-08-26 Auge Wayne K. Methods and compositions for fusing bone during endoscopy procedures
US6902564B2 (en) * 2001-08-15 2005-06-07 Roy E. Morgan Methods and devices for electrosurgery
US7819861B2 (en) * 2001-05-26 2010-10-26 Nuortho Surgical, Inc. Methods for electrosurgical electrolysis
US7771422B2 (en) 2002-06-06 2010-08-10 Nuortho Surgical, Inc. Methods and devices for electrosurgery
US7445619B2 (en) * 2000-08-18 2008-11-04 Map Technologies Llc Devices for electrosurgery
US6547794B2 (en) 2000-08-18 2003-04-15 Auge', Ii Wayne K. Method for fusing bone during endoscopy procedures
US6855135B2 (en) * 2000-11-29 2005-02-15 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6685681B2 (en) * 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US20020091444A1 (en) * 2001-01-05 2002-07-11 Jun Yang Vascular tissue composition
US7066932B1 (en) 2001-05-26 2006-06-27 Map Technologies Llc Biologically enhanced irrigants
US20060004408A1 (en) * 2001-06-08 2006-01-05 Morris Edward J Method and apparatus for sealing access
US20070038244A1 (en) * 2001-06-08 2007-02-15 Morris Edward J Method and apparatus for sealing access
US7993365B2 (en) 2001-06-08 2011-08-09 Morris Innovative, Inc. Method and apparatus for sealing access
JP4170897B2 (ja) 2001-06-08 2008-10-22 モリス イノヴェイティヴ リサーチ， インコーポレイテッド 生体刺入口を封印するための方法および装置
AU2002320189B2 (en) * 2001-06-28 2007-04-26 Cook Biotech Incorporated Graft prosthesis devices containing renal capsule collagen
AU2002354913B2 (en) * 2001-07-16 2008-07-17 Depuy Products, Inc. Unitary surgical device and method
AU2002316694B2 (en) * 2001-07-16 2007-09-06 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
JP4294474B2 (ja) * 2001-07-16 2009-07-15 デピュイ・プロダクツ・インコーポレイテッド 半月板再生装置
AU2002354915B8 (en) * 2001-07-16 2008-04-17 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
ATE499908T1 (de) 2001-07-16 2011-03-15 Depuy Products Inc Gerät zur reparatur von knorpelmaterial
JP4197158B2 (ja) 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 天然に発生する生物学的に誘導されている材料による装置
AU2002320517B2 (en) 2001-07-16 2008-03-13 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorable scaffolds
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
JP4197160B2 (ja) * 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 軟骨修復および再生用の支持骨格材料および方法
US7201917B2 (en) * 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
US8591508B2 (en) * 2001-08-15 2013-11-26 Nuortho Surgical, Inc. Electrosurgical plenum
US8235979B2 (en) 2001-08-15 2012-08-07 Nuortho Surgical, Inc. Interfacing media manipulation with non-ablation radiofrequency energy system and method
US8734441B2 (en) * 2001-08-15 2014-05-27 Nuortho Surgical, Inc. Interfacing media manipulation with non-ablation radiofrequency energy system and method
US20030093041A1 (en) * 2001-10-11 2003-05-15 Risk James R. Waste container for negative pressure therapy
JP2005525140A (ja) * 2001-10-26 2005-08-25 クック・バイオテック・インコーポレーテッド 網状構造を付与した医用移植片デバイス
US7318833B2 (en) * 2001-12-19 2008-01-15 Nmt Medical, Inc. PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
EP1467661A4 (de) * 2001-12-19 2008-11-05 Nmt Medical Inc Septumverschlusseinrichtung und zugehörige verfahren
EP1476217B1 (de) * 2001-12-26 2008-03-05 Hill-Rom Services, Inc. Vakuumbindenverpackung
WO2003057307A1 (en) * 2001-12-26 2003-07-17 Hill-Rom Services, Inc. Wound vacuum therapy dressing kit
CA2468912A1 (en) * 2001-12-26 2003-07-17 Hill-Rom Services, Inc. Vented vacuum bandage and method
WO2003059061A1 (en) 2002-01-11 2003-07-24 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
US7220265B2 (en) * 2002-01-14 2007-05-22 Nmt Medical, Inc. Patent foramen ovale (PFO) closure method and device
EP1487353A4 (de) * 2002-03-25 2008-04-16 Nmt Medical Inc Klemmen zum verschluss eines patenten foramen ovale (pfo)
AU2002359824A1 (en) 2002-04-10 2003-10-27 Hill-Rom Services, Inc. Access openings in vacuum bandage
JP2005533535A (ja) * 2002-05-02 2005-11-10 パーデュー・リサーチ・ファウンデーション 血管新生が促進された移植片構成物
EP2103684A1 (de) 2002-05-02 2009-09-23 Purdue Research Foundation Gefäßneubildungserweiterte Transplantationskonstrukte
AU2003253620A1 (en) * 2002-06-03 2003-12-19 Nmt Medical, Inc. Device with biological tissue scaffold for intracardiac defect closure
JP2005528181A (ja) 2002-06-05 2005-09-22 エヌエムティー メディカル インコーポレイテッド 放射状および円周状支持体を備える卵円孔開存（ｐｆｏ）閉塞デバイス
US7160326B2 (en) * 2002-06-27 2007-01-09 Depuy Products, Inc. Method and apparatus for implantation of soft tissue implant
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
US20040034418A1 (en) * 2002-07-23 2004-02-19 Shu-Tung Li Membrane-reinforced implants
US7550004B2 (en) * 2002-08-20 2009-06-23 Cook Biotech Incorporated Endoluminal device with extracellular matrix material and methods
JP2005536275A (ja) 2002-08-21 2005-12-02 ヒル−ロム サービシズ，インコーポレイテッド 創傷閉鎖を防止するための創傷用パッキング
WO2004037333A1 (en) 2002-10-25 2004-05-06 Nmt Medical, Inc. Expandable sheath tubing
WO2004043508A1 (en) * 2002-11-06 2004-05-27 Nmt Medical, Inc. Medical devices utilizing modified shape memory alloy
DE60325880D1 (de) * 2002-11-07 2009-03-05 Nmt Medical Inc Agnetischer kraft
US7627373B2 (en) * 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
US20040158289A1 (en) * 2002-11-30 2004-08-12 Girouard Steven D. Method and apparatus for cell and electrical therapy of living tissue
US20040187877A1 (en) * 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of liver tissue
US20040191226A1 (en) * 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of body wall
WO2004052213A1 (en) * 2002-12-09 2004-06-24 Nmt Medical, Inc. Septal closure devices
US20040175366A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
US20040176855A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
US7658747B2 (en) * 2003-03-12 2010-02-09 Nmt Medical, Inc. Medical device for manipulation of a medical implant
US20050222687A1 (en) * 2004-04-02 2005-10-06 Gordana Vunjak-Novakovic Cartilage implant assembly and method for implantation
US20050064042A1 (en) * 2003-04-29 2005-03-24 Musculoskeletal Transplant Foundation Cartilage implant plug with fibrin glue and method for implantation
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20090291112A1 (en) * 2003-05-16 2009-11-26 Truncale Katherine G Allograft osteochondral plug combined with cartilage particle mixture
US7488348B2 (en) * 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20050025838A1 (en) * 2003-06-25 2005-02-03 Badylak Stephen F. Conditioned compositions for tissue restoration
US9861346B2 (en) 2003-07-14 2018-01-09 W. L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with linearly elongating petals
US8480706B2 (en) * 2003-07-14 2013-07-09 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US7678123B2 (en) * 2003-07-14 2010-03-16 Nmt Medical, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
EP1659992B1 (de) * 2003-07-31 2013-03-27 Cook Medical Technologies LLC Prothesenklappenvorrichtungen und herstellungsverfahren dafür
WO2005018728A2 (en) * 2003-08-19 2005-03-03 Nmt Medical, Inc. Expandable sheath tubing
WO2005020847A2 (en) 2003-08-25 2005-03-10 Cook Biotech Incorporated Graft materials containing bioactive substances, and methods for their manufacture
US8741352B2 (en) * 2003-08-25 2014-06-03 Cook Biotech Incorporated Graft materials containing ECM components, and methods for their manufacture
US20050054099A1 (en) * 2003-09-04 2005-03-10 Cedars Sinai Medical Center Matrix derived from whole organ
GB2423934B (en) * 2003-09-04 2007-11-28 Cook Biotech Inc Extracellular matrix composite materials, and manufacture and use thereof
US7645229B2 (en) * 2003-09-26 2010-01-12 Armstrong David N Instrument and method for endoscopic visualization and treatment of anorectal fistula
US7657312B2 (en) * 2003-11-03 2010-02-02 Cardiac Pacemakers, Inc. Multi-site ventricular pacing therapy with parasympathetic stimulation
US6976679B2 (en) * 2003-11-07 2005-12-20 The Boeing Company Inter-fluid seal assembly and method therefor
US20050273119A1 (en) * 2003-12-09 2005-12-08 Nmt Medical, Inc. Double spiral patent foramen ovale closure clamp
EP2335650B1 (de) 2003-12-11 2012-10-03 Isto Technologies Inc. Teilchenförmiges Knorpelsystem
AU2005206195B2 (en) 2004-01-21 2011-05-26 Cook Medical Technologies Llc Implantable graft to close a fistula
US8262694B2 (en) * 2004-01-30 2012-09-11 W.L. Gore & Associates, Inc. Devices, systems, and methods for closure of cardiac openings
CA2554460A1 (en) * 2004-02-09 2005-08-25 Cook Biotech Incorporated Stent graft devices having collagen coating
US8337545B2 (en) 2004-02-09 2012-12-25 Cook Medical Technologies Llc Woven implantable device
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
JP2007526087A (ja) * 2004-03-03 2007-09-13 エヌエムティー メディカル， インコーポレイティッド 中隔オクルーダー用の送達／回収システム
US7449027B2 (en) * 2004-03-29 2008-11-11 Cook Incorporated Modifying fluid flow in a body vessel lumen to promote intraluminal flow-sensitive processes
US20050234509A1 (en) * 2004-03-30 2005-10-20 Mmt Medical, Inc. Center joints for PFO occluders
AU2005231781A1 (en) * 2004-03-31 2005-10-20 Cook Incorporated ECM-based graft material
DE602005020754D1 (de) * 2004-03-31 2010-06-02 Cook Inc Transplantatmaterial und gefässprothese mit extrazellulärer kollagenmatrix und dessen herstellungsverfahren
US8216299B2 (en) * 2004-04-01 2012-07-10 Cook Medical Technologies Llc Method to retract a body vessel wall with remodelable material
US20050267524A1 (en) * 2004-04-09 2005-12-01 Nmt Medical, Inc. Split ends closure device
US8361110B2 (en) * 2004-04-26 2013-01-29 W.L. Gore & Associates, Inc. Heart-shaped PFO closure device
US7569233B2 (en) * 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US20050249772A1 (en) * 2004-05-04 2005-11-10 Prasanna Malaviya Hybrid biologic-synthetic bioabsorbable scaffolds
US7842053B2 (en) * 2004-05-06 2010-11-30 Nmt Medical, Inc. Double coil occluder
US8308760B2 (en) 2004-05-06 2012-11-13 W.L. Gore & Associates, Inc. Delivery systems and methods for PFO closure device with two anchors
US7704268B2 (en) * 2004-05-07 2010-04-27 Nmt Medical, Inc. Closure device with hinges
CA2563298A1 (en) 2004-05-07 2005-11-24 Nmt Medical, Inc. Catching mechanisms for tubular septal occluder
WO2005115275A1 (en) * 2004-05-20 2005-12-08 Cook Incorporated Endoluminal device with extracellular matrix material and methods
WO2005118019A1 (en) * 2004-05-28 2005-12-15 Cook Incorporated Implantable bioabsorbable valve support frame
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US20050288796A1 (en) * 2004-06-23 2005-12-29 Hani Awad Native soft tissue matrix for therapeutic applications
JP2008505713A (ja) * 2004-07-07 2008-02-28 クック・インコーポレイテッド グラフト、ステントグラフト、および製造方法
CA2575240A1 (en) * 2004-07-30 2006-02-09 Cook Biotech Incorporated Graft with increased resistance to enzymatic degradation
US8257715B1 (en) 2004-08-26 2012-09-04 University Of Notre Dame Tissue vaccines and uses thereof
EP1827247B8 (de) * 2004-09-24 2020-05-06 W.L. Gore & Associates, Inc. Doppeltes sicherungssystem für eine okklusionsvorrichtung zur abgabe/wiedergewinnung einer okklusionsvorrichtung
US20090149893A1 (en) * 2007-12-05 2009-06-11 Semler Eric J Cancellous Bone Implant for Cartilage Repair
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20080220044A1 (en) * 2007-03-06 2008-09-11 Semler Eric J Cancellous construct with support ring for repair of osteochondral defects
US7442206B2 (en) * 2004-10-28 2008-10-28 Cook Incorporated Methods and systems for modifying vascular valves
US7513866B2 (en) * 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US7387604B2 (en) * 2004-11-03 2008-06-17 Cook Incorporated Methods for treating valve-associated regions of vascular vessels
US7905826B2 (en) * 2004-11-03 2011-03-15 Cook Incorporated Methods for modifying vascular vessel walls
US8329202B2 (en) * 2004-11-12 2012-12-11 Depuy Products, Inc. System and method for attaching soft tissue to an implant
US7744621B2 (en) * 2004-12-06 2010-06-29 Cook Incorporated Inflatable occlusion devices, methods, and systems
WO2006062976A2 (en) * 2004-12-07 2006-06-15 Cook Incorporated Methods for modifying vascular vessel walls
US8060219B2 (en) * 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7981065B2 (en) * 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US8874204B2 (en) * 2004-12-20 2014-10-28 Cardiac Pacemakers, Inc. Implantable medical devices comprising isolated extracellular matrix
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
EP1833384B1 (de) * 2004-12-30 2017-08-16 Cook Medical Technologies LLC Invertierende okklusionsvorichtungen und systeme
WO2008098255A2 (en) * 2007-02-09 2008-08-14 Taheri Laduca Llc Apparatus and method for deploying an implantable device within the body
US20070150051A1 (en) * 2005-01-10 2007-06-28 Duke Fiduciary, Llc Vascular implants and methods of fabricating the same
US8128680B2 (en) 2005-01-10 2012-03-06 Taheri Laduca Llc Apparatus and method for deploying an implantable device within the body
US8287583B2 (en) 2005-01-10 2012-10-16 Taheri Laduca Llc Apparatus and method for deploying an implantable device within the body
US20060206139A1 (en) * 2005-01-19 2006-09-14 Tekulve Kurt J Vascular occlusion device
US20060246033A1 (en) * 2005-03-02 2006-11-02 Cook Biotech Incorporated Injectable bulking agent compositions
US9138445B2 (en) * 2005-03-09 2015-09-22 Cook Biotech Incorporated Medical graft materials with adherent extracellular matrix fibrous mass
US7840266B2 (en) * 2005-03-11 2010-11-23 Cardiac Pacemakers, Inc. Integrated lead for applying cardiac resynchronization therapy and neural stimulation therapy
JP5028404B2 (ja) 2005-03-11 2012-09-19 カーディアック ペースメイカーズ， インコーポレイテッド 神経刺激および心臓再同期併用治療
US7587238B2 (en) * 2005-03-11 2009-09-08 Cardiac Pacemakers, Inc. Combined neural stimulation and cardiac resynchronization therapy
EP1868507A1 (de) 2005-03-18 2007-12-26 NMT Medical, Inc. Riegelelement für pfo-okkludierer
WO2006102063A2 (en) * 2005-03-19 2006-09-28 Cook Biotech Incorporated Prosthetic implants including ecm composite material
US8197534B2 (en) * 2005-03-31 2012-06-12 Cook Medical Technologies Llc Valve device with inflatable chamber
US20060229670A1 (en) * 2005-04-01 2006-10-12 Bates Brian L Method and a medical closure system for sealing a puncture
US9956315B2 (en) * 2005-04-29 2018-05-01 Cook Biotech Incorporated Fistula graft with deformable sheet-form material
JP4995811B2 (ja) 2005-04-29 2012-08-08 クック・バイオテック・インコーポレーテッド 瘻治療用容積式移植片並びに関連の方法及びシステム
WO2006121887A2 (en) * 2005-05-05 2006-11-16 Cook Biotech Incorporated Implantable materials and methods for inhibiting tissue adhesion formation
US8518436B2 (en) * 2005-05-16 2013-08-27 Purdue Research Foundation Engineered extracellular matrices
AU2006262178B2 (en) 2005-06-21 2012-07-05 Cook Biotech, Inc. Implantable graft to close a fistula
US20060292227A1 (en) * 2005-06-23 2006-12-28 Mcpherson Timothy B Extracellular matrix material particles and methods of preparation
US20060293760A1 (en) * 2005-06-24 2006-12-28 Dedeyne Patrick G Soft tissue implants with improved interfaces
US7815926B2 (en) * 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
WO2007011644A2 (en) * 2005-07-15 2007-01-25 Cormatrix Cardiovascular, Inc. Compositions for regenerating defective or absent tissue
US9072816B2 (en) * 2006-01-18 2015-07-07 Cormatrix Cardiovascular, Inc. Composition for modulating inflammation of cardiovascular tissue
US8568761B2 (en) * 2005-07-15 2013-10-29 Cormatrix Cardiovascular, Inc. Compositions for regenerating defective or absent myocardium
US20080279939A1 (en) * 2007-05-10 2008-11-13 Firestone Leigh H Extracellular matrix compositions for tissue regeneration
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
WO2007025290A2 (en) 2005-08-26 2007-03-01 Isto Technologies, Inc. Implants and methods for repair, replacement and treatment of joint disease
WO2007028052A2 (en) * 2005-09-01 2007-03-08 Cook Incorporated Attachment of material to an implantable frame by cross-linking
US7797056B2 (en) * 2005-09-06 2010-09-14 Nmt Medical, Inc. Removable intracardiac RF device
US9259267B2 (en) 2005-09-06 2016-02-16 W.L. Gore & Associates, Inc. Devices and methods for treating cardiac tissue
US20070088388A1 (en) * 2005-09-19 2007-04-19 Opolski Steven W Delivery device for implant with dual attachment sites
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US20070082021A1 (en) * 2005-09-30 2007-04-12 Bates Brian L Coated vaso-occlusion device
CA2627285A1 (en) * 2005-10-24 2007-10-25 Nmt Medical, Inc. Radiopaque bioabsorbable occluder
US8778362B2 (en) 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
US8802113B2 (en) * 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US9308252B2 (en) * 2005-10-27 2016-04-12 Cook Biotech, Inc. Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
US8778360B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US20070112360A1 (en) * 2005-11-15 2007-05-17 Patrick De Deyne Bioprosthetic device
AU2006320507B2 (en) * 2005-12-02 2012-11-01 Cook Medical Technologies Llc Devices, systems, and methods for occluding a defect
US20070167981A1 (en) * 2005-12-22 2007-07-19 Nmt Medical, Inc. Catch members for occluder devices
WO2007081530A2 (en) * 2006-01-03 2007-07-19 Med Institute, Inc. Endoluminal medical device for local delivery of cathepsin inhibitors
AU2007208243B2 (en) 2006-01-25 2013-09-19 Children's Medical Center Corporation Methods and procedures for ligament repair
WO2007090150A2 (en) * 2006-01-31 2007-08-09 Cook Biotech Incorporated Fistula grafts and related methods and systems for treating fistulae
US8211168B2 (en) * 2006-02-21 2012-07-03 Cook Biotech Incorporated Graft material, stent graft and method
US20070196380A1 (en) * 2006-02-22 2007-08-23 Leigh H. Firestone Extracellular matrix to treat malignancy in mammals
US8870913B2 (en) 2006-03-31 2014-10-28 W.L. Gore & Associates, Inc. Catch system with locking cap for patent foramen ovale (PFO) occluder
JP2009532125A (ja) * 2006-03-31 2009-09-10 エヌエムティー メディカル， インコーポレイティッド オクルーダ装置用の変形可能なフラップキャッチ機構
US8551135B2 (en) 2006-03-31 2013-10-08 W.L. Gore & Associates, Inc. Screw catch mechanism for PFO occluder and method of use
WO2007136634A1 (en) * 2006-05-16 2007-11-29 Purdue Research Foundation Three dimensional purified collagen matrices
US20070269476A1 (en) * 2006-05-16 2007-11-22 Voytik-Harbin Sherry L Engineered extracellular matrices control stem cell behavior
US8974542B2 (en) * 2006-06-27 2015-03-10 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable elastomeric patch for treating cardiac or cardiovascular conditions
WO2008008266A2 (en) * 2006-07-07 2008-01-17 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Biohybrid elastomeric scaffolds and methods of use thereof
WO2008024920A1 (en) * 2006-08-24 2008-02-28 Wilson-Cook Medical Inc. Devices and methods for occluding a fistula
US20080063627A1 (en) * 2006-09-12 2008-03-13 Surmodics, Inc. Tissue graft materials containing biocompatible agent and methods of making and using same
GB2455041B (en) 2006-09-21 2012-03-07 Purdue Research Foundation Collagen preparation and method of isolation
US20080082083A1 (en) * 2006-09-28 2008-04-03 Forde Sean T Perforated expandable implant recovery sheath
WO2008060361A2 (en) 2006-09-28 2008-05-22 Children's Medical Center Corporation Methods and collagen products for tissue repair
AU2007325460B2 (en) * 2006-10-23 2013-09-05 Cook Biotech Incorporated Processed ECM materials with enhanced component profiles
US8790414B2 (en) 2006-11-10 2014-07-29 Cook Biotech Incorporated Graft for hysterotomy closure
US7871440B2 (en) * 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US20080154233A1 (en) * 2006-12-20 2008-06-26 Zimmer Orthobiologics, Inc. Apparatus for delivering a biocompatible material to a surgical site and method of using same
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
US9526642B2 (en) * 2007-02-09 2016-12-27 Taheri Laduca Llc Vascular implants and methods of fabricating the same
WO2008109407A2 (en) 2007-03-02 2008-09-12 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Extracellular matrix-derived gels and related methods
US8435551B2 (en) * 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
WO2008124603A1 (en) 2007-04-05 2008-10-16 Nmt Medical, Inc. Septal closure device with centering mechanism
WO2008124361A2 (en) * 2007-04-06 2008-10-16 Cook Biotech Incorporated Fistula plugs having increased column strength and fistula plug delivery apparatuses and methods
EP2134297B1 (de) 2007-04-12 2017-03-08 Zimmer, Inc. Vorrichtung zur gewebereparatur
US9138562B2 (en) 2007-04-18 2015-09-22 W.L. Gore & Associates, Inc. Flexible catheter system
US20080279833A1 (en) * 2007-05-10 2008-11-13 Matheny Robert G Laminate sheet articles for tissue regeneration
US9283302B2 (en) 2011-12-16 2016-03-15 Cormatrix Cardiovascular, Inc. Extracellular matrix encasement structures and methods
US20220023503A9 (en) 2007-05-10 2022-01-27 Aziyo Med, Llc Extracellular Matrix Tissue Prostheses
US8535349B2 (en) * 2007-07-02 2013-09-17 Cook Biotech Incorporated Fistula grafts having a deflectable graft body portion
US20090024106A1 (en) * 2007-07-17 2009-01-22 Morris Edward J Method and apparatus for maintaining access
US9113851B2 (en) 2007-08-23 2015-08-25 Cook Biotech Incorporated Fistula plugs and apparatuses and methods for fistula plug delivery
US20090062839A1 (en) * 2007-08-31 2009-03-05 Cook Incorporated Barbed stent vascular occlusion device
US8292907B2 (en) * 2007-08-31 2012-10-23 Cook Medical Technologies Llc Balloon assisted occlusion device
US20090069843A1 (en) * 2007-09-10 2009-03-12 Agnew Charles W Fistula plugs including a hydration resistant component
WO2009036250A1 (en) 2007-09-12 2009-03-19 Cook Incorporated Enhanced remodelable materials for occluding bodily vessels and related methods and systems
US20090082816A1 (en) 2007-09-20 2009-03-26 Graham Matthew R Remodelable orthopaedic spacer and method of using the same
US7846199B2 (en) * 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
CA2708615C (en) * 2007-12-10 2019-12-31 Purdue Research Foundation Collagen-based matrices with stem cells
US20090171406A1 (en) * 2007-12-12 2009-07-02 Cardiac Pacemakers, Inc. Electrically conducting scaffolds for cell-based pacing
US8257434B2 (en) 2007-12-18 2012-09-04 Cormatrix Cardiovascular, Inc. Prosthetic tissue valve
US20090157170A1 (en) * 2007-12-18 2009-06-18 Matheny Robert G Trileaflet Semi-Lunar Prosthetic Tissue Valve
US8679176B2 (en) 2007-12-18 2014-03-25 Cormatrix Cardiovascular, Inc Prosthetic tissue valve
US20090157177A1 (en) * 2007-12-18 2009-06-18 Matheny Robert G Sewing Ring for a Prosthetic Tissue Valve
WO2009086499A2 (en) * 2007-12-28 2009-07-09 Cook Biotech Incorporated Medical composition including an extracellular matrix particulate
US9283266B2 (en) * 2008-02-28 2016-03-15 University Of Notre Dame Metastasis inhibition preparations and methods
WO2009111306A2 (en) * 2008-02-29 2009-09-11 Cook Biotech Incorporated Coated embolization device
CA2717725A1 (en) * 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US20130165967A1 (en) 2008-03-07 2013-06-27 W.L. Gore & Associates, Inc. Heart occlusion devices
GB2471635B (en) * 2008-05-29 2012-09-26 Cook Biotech Inc Devices for treating rectovaginal and other fistulae
US9295757B2 (en) 2008-06-10 2016-03-29 Cook Biotech Incorporated Quilted implantable graft
US8118832B1 (en) 2008-06-16 2012-02-21 Morris Innovative, Inc. Method and apparatus for sealing access
JP5722217B2 (ja) 2008-09-02 2015-05-20 アラーガン・ホールディングス・フランス・ソシエテ・パール・アクシオン・サンプリフィエＡｌｌｅｒｇａｎ Ｈｏｌｄｉｎｇｓ Ｆｒａｎｃｅ Ｓ．Ａ．Ｓ． ヒアルロン酸および／またはその誘導体の糸、その作製方法、ならびにその使用
US8858698B2 (en) 2008-09-05 2014-10-14 Mentor Worldwide Llc Acellular matrix glue
US7927414B2 (en) * 2008-09-05 2011-04-19 Ethicon, Inc. Method of manufacturing acellular matrix glue
AU2009298560B2 (en) 2008-09-30 2014-05-01 The Regents Of The University Of California Compositions and methods for tissue repair with extracellular matrices
WO2010078478A1 (en) 2008-12-31 2010-07-08 Cook Biotech Incorporated Tissue adjuvants and medical products including the same
US8469779B1 (en) 2009-01-02 2013-06-25 Lifecell Corporation Method for debristling animal skin
WO2010083051A2 (en) * 2009-01-15 2010-07-22 ProChon Biotech, Ltd. Cartilage particle tissue mixtures optionally combined with a cancellous construct
WO2010088678A2 (en) 2009-02-02 2010-08-05 Cook Biotech Incorporated Medical bead products
MX2011008735A (es) * 2009-02-18 2012-01-12 Cormatrix Cardiovascular Inc Composiciones y metodos para prevenir la arritmia cardiaca.
EP2403438B1 (de) 2009-03-04 2021-04-21 Peytant Solutions, Inc. Mit amniongewebehaltigem material modizifierte stents und zugehörige verfahren
CA2760889C (en) 2009-05-06 2017-09-19 Hansa Medical Products, Inc. Self-adjusting medical device
US9532827B2 (en) 2009-06-17 2017-01-03 Nuortho Surgical Inc. Connection of a bipolar electrosurgical hand piece to a monopolar output of an electrosurgical generator
US20120029556A1 (en) 2009-06-22 2012-02-02 Masters Steven J Sealing device and delivery system
US8956389B2 (en) 2009-06-22 2015-02-17 W. L. Gore & Associates, Inc. Sealing device and delivery system
US8652500B2 (en) 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
US8298586B2 (en) 2009-07-22 2012-10-30 Acell Inc Variable density tissue graft composition
US8846059B2 (en) 2009-12-08 2014-09-30 University Of Notre Dame Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer
US20110150934A1 (en) * 2009-12-18 2011-06-23 University Of Notre Dame Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer
WO2011150328A1 (en) 2010-05-27 2011-12-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Wet-electrospun biodegradable scaffold and uses therefor
EP3888714B8 (de) 2010-07-31 2025-05-21 Cook Biotech Incorporated Kollagene gewebstasche für ein implantierbares medizinisches gerät und herstellungsverfahren dafür
WO2012024390A2 (en) 2010-08-17 2012-02-23 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biohybrid composite scaffold
DK2608777T3 (en) 2010-08-24 2019-10-28 Univ California Compositions and Methods for Cardiac Therapy
US9408658B2 (en) 2011-02-24 2016-08-09 Nuortho Surgical, Inc. System and method for a physiochemical scalpel to eliminate biologic tissue over-resection and induce tissue healing
WO2012142419A1 (en) 2011-04-14 2012-10-18 Lifecell Corporation Regenerative materials
SG194878A1 (en) 2011-05-27 2013-12-30 Cormatrix Cardiovascular Inc Extracellular matrix material conduits and methods of making and using same
WO2012166549A1 (en) 2011-05-27 2012-12-06 Cormatrix Cardiovascular, Inc. Extracellular matrix material valve conduit and methods of making thereof
EP2717790B1 (de) 2011-06-06 2019-08-21 Muffin Incorporated Gefässverschlussvorrichtungen
US9089523B2 (en) 2011-07-28 2015-07-28 Lifecell Corporation Natural tissue scaffolds as tissue fillers
US9770232B2 (en) 2011-08-12 2017-09-26 W. L. Gore & Associates, Inc. Heart occlusion devices
WO2013036708A2 (en) 2011-09-07 2013-03-14 The Regents Of The University Of California Compositions and methods for tissue repair with extracellular matrices
US20140302480A1 (en) 2011-11-09 2014-10-09 The General Hospital Corporation Composite tissue graft and materials and methods for its production and use
CA2860850C (en) 2011-12-20 2019-05-21 Lifecell Corporation Sheet tissue products
CA2859657C (en) 2011-12-20 2021-03-02 Lifecell Corporation Acellular tissue matrix particles and flowable products comprising them
EP3797801A1 (de) 2012-01-24 2021-03-31 LifeCell Corporation Längliche gewebematrizen
US11484578B2 (en) 2012-02-01 2022-11-01 Children's Medical Center Corporation Biomaterial for articular cartilage maintenance and treatment of arthritis
US10940167B2 (en) 2012-02-10 2021-03-09 Cvdevices, Llc Methods and uses of biological tissues for various stent and other medical applications
US9504458B2 (en) 2012-02-17 2016-11-29 Cook Biotech Incorporated Methods and systems for treating complex fistulae
BR112014026090A8 (pt) 2012-04-24 2019-08-27 Lifecell Corp composição de matriz tecidual apta a fluir
ES2753156T3 (es) 2012-07-13 2020-04-07 Lifecell Corp Procedimientos de tratamiento mejorado de tejido adiposo
AU2013323747B2 (en) 2012-09-26 2017-02-02 Lifecell Corporation Processed adipose tissue
US9579142B1 (en) 2012-12-13 2017-02-28 Nuortho Surgical Inc. Multi-function RF-probe with dual electrode positioning
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
US10828019B2 (en) 2013-01-18 2020-11-10 W.L. Gore & Associates, Inc. Sealing device and delivery system
US12599700B2 (en) 2013-02-01 2026-04-14 The Children's Medical Center Corporation System and methods for connective tissue repair using scaffolds
US9757495B2 (en) 2013-02-01 2017-09-12 Children's Medical Center Corporation Collagen scaffolds
CN104994893B (zh) 2013-02-06 2018-01-05 生命细胞公司 用于组织产物的局部改性的方法
US20140228937A1 (en) 2013-02-11 2014-08-14 Joshua Krieger Expandable Support Frame and Medical Device
US20160045552A1 (en) * 2013-04-08 2016-02-18 Asana Medical, Inc. Method and composition for treating inflammatory bowel disease without colectomy
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
CN106456837B (zh) 2014-03-21 2020-04-10 匹兹堡大学-联邦高等教育体系 最终消毒的来自细胞外基质的水凝胶的制备方法
US9808230B2 (en) 2014-06-06 2017-11-07 W. L. Gore & Associates, Inc. Sealing device and delivery system
EP4548939A3 (de) 2014-08-27 2025-08-06 Purdue Research Foundation Abgabesysteme für therapeutikum auf kollagenbasis
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
US11919941B2 (en) 2015-04-21 2024-03-05 Purdue Research Foundation Cell-collagen-silica composites and methods of making and using the same
AU2015407008B2 (en) 2015-08-21 2020-08-13 Cormatrix Cardiovascular, Inc. Extracellular matrix prostheses for treating damaged biological tissue
WO2017062762A2 (en) 2015-10-07 2017-04-13 Sigmon John C Methods, medical devices and kits for modifying the luminal profile of a body vessel
KR102805970B1 (ko) 2016-03-02 2025-05-09 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 매트릭스가 결합된 나노소낭 및 그의 용도
US11389566B2 (en) 2016-03-14 2022-07-19 Regentys Corporation Method and composition for treating inflammatory bowel disease
CA3025501A1 (en) 2016-06-03 2017-12-07 Lifecell Corporation Methods for localized modification of tissue products
US12377193B2 (en) 2016-07-06 2025-08-05 The Children's Medical Center Corporation Indirect method of articular tissue repair
RU2627844C1 (ru) * 2016-10-24 2017-08-14 Общество С Ограниченной Ответственностью "Ниармедик Плюс" Способ получения суспензионной формы измельченного децеллюляризованного внеклеточного матрикса
WO2018118944A1 (en) 2016-12-22 2018-06-28 Lifecell Corporation Devices and methods for tissue cryomilling
ES3040675T3 (en) 2017-01-31 2025-11-04 Geniphys Inc Methods and compositions for matrix preparation
AU2018226871B2 (en) 2017-03-02 2023-08-10 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ECM) hydrogel and soluble fraction thereof for the treatment of cancer
AU2018226867B2 (en) 2017-03-02 2023-11-02 University Of Pittsburgh - Of The Commonwealth System Of Higher Education ECM hydrogel for treating esophageal inflammation
US11739291B2 (en) 2017-04-25 2023-08-29 Purdue Research Foundation 3-dimensional (3D) tissue-engineered muscle for tissue restoration
EP3697460A1 (de) 2017-10-18 2020-08-26 LifeCell Corporation Fettgewebeprodukte und verfahren zur herstellung
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
EP4309686A3 (de) 2017-10-19 2024-02-07 LifeCell Corporation Fliessfähige azelluläre gewebematrixprodukte und herstellungsverfahren
EP3787642A4 (de) 2018-05-03 2022-09-21 University of Pittsburgh - of the Commonwealth System of Higher Education Il-33-haltige matrix-gebundene vesikel (mbvs) und deren verwendung
JP2021527518A (ja) 2018-06-21 2021-10-14 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 食道粘膜下流体クッションとしての膀胱ｅｃｍヒドロゲルの使用
WO2019246444A1 (en) 2018-06-21 2019-12-26 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ecm) hydrogel as a submucosal fluid cushion
EP3976127B1 (de) 2019-05-30 2025-09-24 LifeCell Corporation Biologisches brustimplantat
CA3168904A1 (en) 2020-01-27 2021-08-05 Geniphys, Inc. Biologic filler for restoring and regenerating tissue
EP4121073B1 (de) 2020-03-16 2024-07-03 Biosearch S.A. Biokomposite mit probiotika, kollagen und bakteriellem extrazellulärem polysaccharid und verwendungen davon
WO2022040206A1 (en) 2020-08-17 2022-02-24 Aziyo Med, Llc Depots and encasement structures for implantable devices
US11826490B1 (en) 2020-12-29 2023-11-28 Acell, Inc. Extracellular matrix sheet devices with improved mechanical properties and method of making

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2090558B (en) * 1981-01-06 1984-08-30 British Gas Corp Method of manufacture of a heat sealable fitting and fitting made by such method
US4502161A (en) * 1981-09-21 1985-03-05 Wall W H Prosthetic meniscus for the repair of joints
JPS624991A (ja) * 1985-06-28 1987-01-10 三菱樹脂株式会社 プラスチツク管の接合方法
JPS63272535A (ja) * 1987-05-01 1988-11-10 Nippon Denso Co Ltd 電磁誘導接着用加熱装置
US4880429A (en) * 1987-07-20 1989-11-14 Stone Kevin R Prosthetic meniscus
US4902508A (en) * 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US4956178A (en) * 1988-07-11 1990-09-11 Purdue Research Foundation Tissue graft composition
JPH0739119B2 (ja) * 1988-07-11 1995-05-01 積水化学工業株式会社 溶着継手の製造方法
US5231169A (en) * 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
US5204382A (en) * 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use

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