ATE250425T1 - Analoga des parathyroid-hormons - Google Patents

Analoga des parathyroid-hormons

Info

Publication number: ATE250425T1
Authority: AT; Austria
Prior art keywords: amino acid; parathyroid hormone; analogues; acid residue; alpha
Prior art date: 1995-07-13

Application number

AT96924355T

Other languages

English (en)

Inventor

Zheng Xin Dong

Original Assignee

Sod Conseils Rech Applic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-13

Filing date

1996-07-03

Publication date

2003-10-15

1996-07-03 Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic

2003-10-15 Application granted granted Critical

2003-10-15 Publication of ATE250425T1 publication Critical patent/ATE250425T1/de

Links

102000003982 Parathyroid hormone Human genes 0.000 title abstract 2
108090000445 Parathyroid hormone Proteins 0.000 title abstract 2
239000000199 parathyroid hormone Substances 0.000 title abstract 2
229960001319 parathyroid hormone Drugs 0.000 title abstract 2
125000000539 amino acid group Chemical group 0.000 abstract 5
FUOOLUPWFVMBKG-UHFFFAOYSA-N 2-Aminoisobutyric acid Chemical compound CC(C)(N)C(O)=O FUOOLUPWFVMBKG-UHFFFAOYSA-N 0.000 abstract 2
PECYZEOJVXMISF-UHFFFAOYSA-N 3-aminoalanine Chemical compound [NH3+]CC(N)C([O-])=O PECYZEOJVXMISF-UHFFFAOYSA-N 0.000 abstract 2
BVAUMRCGVHUWOZ-ZETCQYMHSA-N (2s)-2-(cyclohexylazaniumyl)propanoate Chemical compound OC(=O)[C@H](C)NC1CCCCC1 BVAUMRCGVHUWOZ-ZETCQYMHSA-N 0.000 abstract 1
QUOGESRFPZDMMT-UHFFFAOYSA-N L-Homoarginine Natural products OC(=O)C(N)CCCCNC(N)=N QUOGESRFPZDMMT-UHFFFAOYSA-N 0.000 abstract 1
QUOGESRFPZDMMT-YFKPBYRVSA-N L-homoarginine Chemical compound OC(=O)[C@@H](N)CCCCNC(N)=N QUOGESRFPZDMMT-YFKPBYRVSA-N 0.000 abstract 1
LRQKBLKVPFOOQJ-YFKPBYRVSA-N L-norleucine Chemical compound CCCC[C@H]([NH3+])C([O-])=O LRQKBLKVPFOOQJ-YFKPBYRVSA-N 0.000 abstract 1
239000012634 fragment Substances 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Physical Education & Sports Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Orthopedic Medicine & Surgery (AREA)
Obesity (AREA)
Hematology (AREA)
Analytical Chemistry (AREA)
Immunology (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT96924355T 1995-07-13 1996-07-03 Analoga des parathyroid-hormons ATE250425T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US110595P	1995-07-13	1995-07-13
US330595P	1995-09-06	1995-09-06
US08/626,186 US5723577A (en)	1995-07-13	1996-03-29	Analogs of parathyroid hormone
PCT/US1996/011292 WO1997002834A1 (en)	1995-07-13	1996-07-03	Analogs of parathyroid hormone

Publications (1)

Publication Number	Publication Date
ATE250425T1 true ATE250425T1 (de)	2003-10-15

Family

ID=27356825

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT96924355T ATE250425T1 (de)	1995-07-13	1996-07-03	Analoga des parathyroid-hormons
AT03077383T ATE442159T1 (de)	1995-07-13	1996-07-03	Parathyroidhormon analoge

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT03077383T ATE442159T1 (de)	1995-07-13	1996-07-03	Parathyroidhormon analoge

Country Status (19)

Country	Link
US (1)	US5723577A (de)
EP (2)	EP1405861B1 (de)
JP (3)	JPH11509201A (de)
KR (5)	KR100563600B1 (de)
CN (3)	CN100412091C (de)
AT (2)	ATE250425T1 (de)
AU (1)	AU707094B2 (de)
DE (2)	DE69630133T2 (de)
DK (2)	DK0847278T3 (de)
ES (2)	ES2207680T3 (de)
HU (1)	HU226935B1 (de)
IL (1)	IL122837A (de)
MX (1)	MX9800418A (de)
NZ (1)	NZ312899A (de)
PL (1)	PL186710B1 (de)
PT (2)	PT847278E (de)
SK (1)	SK3198A3 (de)
TW (1)	TW482766B (de)
WO (1)	WO1997002834A1 (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6110892A (en) *	1994-06-20	2000-08-29	National Research Council Of Canada	Parathyroid hormone analogues for the treatment of osteoporosis
US5955425A (en) *	1996-08-02	1999-09-21	National Research Council Of Canada	Parathyroid hormone analogues for the treatment of osteoporosis
US6544949B1 (en) *	1995-07-13	2003-04-08	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Analogs of parathyroid hormone
US7410948B2 (en) *	1995-07-13	2008-08-12	Societe De Conseils De Recherches Et D'applications Scientifiques, Sas	Analogs of parathyroid hormone
US5955574A (en) *	1995-07-13	1999-09-21	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.	Analogs of parathyroid hormone
US5969095A (en) *	1995-07-13	1999-10-19	Biomeasure, Inc.	Analogs of parathyroid hormone
AP9901686A0 (en) *	1997-05-14	1999-12-31	Rhone Poulenc Rorer Pharma	Peptide parathyroid hormone analogs.
CN1210059C (zh)	1997-09-09	2005-07-13	弗·哈夫曼-拉罗切有限公司	使用PTHrP类似物的骨折愈合
US7531621B1 (en) *	1998-05-05	2009-05-12	Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S.	PTH2 receptor selective compounds
PL345583A1 (en) *	1998-07-20	2001-12-17	Sod Conseils Rech Applic	Peptide analogues of pacap
EP1123401A1 (de) *	1998-10-22	2001-08-16	The General Hospital Corporation	Bioaktive peptide und peptid-derivate von parathyroidhormon (pth) und parathyroidhormon verwandte peptide (pthrp)
US7169567B1 (en)	1998-12-31	2007-01-30	The General Hospital Corporation	Screening assay utilizing the PTH receptor
US6689566B1 (en) *	1999-01-14	2004-02-10	Scantibodies Laboratory, Inc.	Methods, kits, and antibodies for detecting parathyroid hormone
US7820393B2 (en) *	1999-01-14	2010-10-26	Scantibodies Laboratory, Inc.	Methods, kits and antibodies for detecting parathyroid hormone
WO2004028444A2 (en) *	1999-06-02	2004-04-08	Scantibodies Laboratory, Inc.	Parathyroid hormone antagonists and uses thereof
US20080108086A1 (en) *	1999-06-02	2008-05-08	Cantor Thomas L	Parathyroid hormone antagonists and uses thereof
WO2001023521A2 (en) *	1999-09-29	2001-04-05	The General Hospital Corporation	Polypeptide derivatives of parathyroid hormone (pth)
US7022815B1 (en)	1999-09-29	2006-04-04	The General Hospital Corporation	Polypeptide derivatives of parathyroid hormone (PTH)
ATE412670T1 (de)	1999-09-29	2008-11-15	Gen Hospital Corp	Parathyroid hormon (pth) polypeptidderivate
US20050124537A1 (en) *	2000-04-27	2005-06-09	Amgen Inc.	Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US6756480B2 (en)	2000-04-27	2004-06-29	Amgen Inc.	Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
PL211976B1 (pl)	2001-06-01	2012-07-31	Novartis Ag	Kompozycja farmaceutyczna do podawania doustnego oraz zastosowanie kompozycji
KR100491737B1 (ko) *	2001-07-20	2005-05-27	주식회사 한국아이템개발	공기 정화 기능의 모기 퇴치기
AU2002339843B2 (en)	2001-07-23	2007-12-06	The General Hospital Corporation	Conformationally constrained parathyroid hormone (PTH) analogs
US20040067526A1 (en) *	2002-10-03	2004-04-08	Cantor Thomas L.	Methods for diagnosing and guiding treatment of bone turnover disease
AU2003220380A1 (en) *	2003-03-19	2004-11-19	Bristol-Myers Squibb Company	CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH Alpha-HELIX STABILIZERS
KR100540659B1 (ko) *	2003-07-02	2006-01-10	삼성전자주식회사	이미지 확대 인쇄 방법과 장치 및 컴퓨터 프로그램을저장하는 컴퓨터로 읽을 수 있는 기록 매체
JP4871128B2 (ja)	2003-07-17	2012-02-08	ザジェネラルホスピタルコーポレイション	高次構造的に制約された副甲状腺ホルモン（ｐｔｈ）アナログ
MXPA06001428A (es) *	2003-08-06	2006-05-15	Rhodia	Metodo para promover el crecimiento del hueso.
US7465703B1 (en)	2003-10-01	2008-12-16	Scantibodies Laboratory, Inc.	Methods and kits useful for guiding osteoporosis related therapy
US7541140B2 (en) *	2004-06-03	2009-06-02	Scantibodies Laboratory, Inc.	Assessing risk for kidney stones using parathyroid hormone agonist and antagonist
AU2006315132A1 (en) *	2005-11-10	2007-05-24	Board Of Control Of Michigan Technological University	Black bear parathyroid hormone and methods of using black bear parathyroid hormone
WO2008019062A2 (en) *	2006-08-04	2008-02-14	The General Hospital Corporation	Polypeptide derivatives of parathyroid hormone (pth)
DK2957278T3 (en) *	2006-10-03	2017-07-31	Radius Health Inc	STABLE COMPOSITION COMPREHENSIVE PTHRP AND APPLICATIONS THEREOF
US7803770B2 (en)	2006-10-03	2010-09-28	Radius Health, Inc.	Method of treating osteoporosis comprising administration of PTHrP analog
USRE49444E1 (en)	2006-10-03	2023-03-07	Radius Health, Inc.	Method of treating osteoporosis comprising administration of PTHrP analog
CA2672907C (en)	2006-10-13	2013-08-06	Eli Lilly And Company	Pegylated pth as pth receptor modulators and uses thereof
EP1961765A1 (de) *	2006-12-08	2008-08-27	Zealand Pharma A/S	Verkürzte PTH-Peptide mit zyklischer Konformation
MX346714B (es) *	2007-08-01	2017-03-24	The General Hospital Corp *	Metodos de analisis y seleccion usando receptores acoplados a proteina g y composiciones relacionadas.
US8563513B2 (en)	2009-03-27	2013-10-22	Van Andel Research Institute	Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
JP2013512688A (ja)	2009-12-07	2013-04-18	ミシガンテクノロジカルユニバーシティ	クロクマの副甲状腺ホルモン及びクロクマの副甲状腺ホルモンを使用する方法
LT2568806T (lt)	2010-05-12	2016-09-26	Radius Health, Inc.	Terapiniai režimai
CN103002906B (zh)	2010-05-13	2017-12-29	总医院有限公司	甲状旁腺激素类似物及其应用
ES2550319T3 (es)	2010-09-28	2015-11-06	Radius Health, Inc	Moduladores selectivos del receptor de andrógenos
WO2012111852A1 (ja) *	2011-02-17	2012-08-23	帝人ファーマ株式会社	椎体骨折治療剤及びその評価方法
RS64115B1 (sr)	2014-03-28	2023-04-28	Univ Duke	Lečenje kancera dojke upotrebom selektivnih modulatora receptora estrogena
IL310069B2 (en)	2015-04-29	2025-08-01	Radius Pharmaceuticals Inc	Rad1901 for use in the treatment of cancer
EP4066827A1 (de)	2016-06-22	2022-10-05	Ellipses Pharma Ltd	Verfahren zur behandlung von ar+-brustkrebs
CN117417263A (zh)	2017-01-05	2024-01-19	雷迪厄斯制药公司	Rad1901-2hcl的多晶型形式
US10996208B2 (en)	2017-04-28	2021-05-04	Radius Health, Inc.	Abaloparatide formulations and methods of testing, storing, modifying, and using same
EP3765488A1 (de)	2018-03-12	2021-01-20	Fresenius Kabi iPSUM S.r.l.	Verfahren zur herstellung von pthrp-analog
KR102792490B1 (ko)	2018-07-04	2025-04-04	래디어스 파마슈티컬스, 인코포레이티드	Rad1901-2hcl의 다형 형태
JP7667083B2 (ja)	2019-02-12	2025-04-22	ラジウスファーマシューティカルズ，インコーポレイテッド	方法および化合物
WO2023223296A1 (en) *	2022-05-20	2023-11-23	Radius Health, Inc.	Process of making abaloparatide

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2550204B1 (fr) *	1983-08-05	1987-11-13	Toyo Jozo Kk	Derives peptidiques de (nle8,nle1b, tyr34)-h-pth
EP0293158A3 (de) *	1987-05-26	1990-05-09	Merck & Co. Inc.	Parathyroide Hormon-Antagonisten
EP0411096A1 (de) *	1989-02-23	1991-02-06	Gesellschaft für Biotechnologische Forschung mbH (GBF)	Pth-varianten kodierende dna-sequenzen, pth-varianten, expressionsvektor, bakterieller wirt, verwendung und therapeutische zusammensetzung
CA2040264A1 (en) *	1990-04-12	1991-10-13	Tatsuhiko Kanmera	Parathyroid hormone antagonists
WO1993006846A1 (en) *	1991-10-10	1993-04-15	Pang Peter K T	Parathyroid hormone analogues and use in osteoporosis treatment
US5434246A (en) *	1992-03-19	1995-07-18	Takeda Chemical Industries, Ltd.	Parathyroid hormone derivatives
CA2098639A1 (en) *	1992-06-19	1993-12-20	K. Anne Kronis	Bone stimulating, non-vasoactive parathyroid hormone variants
US5589452A (en) *	1992-07-14	1996-12-31	Syntex (U.S.A.) Inc.	Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
AU672790B2 (en) *	1992-07-15	1996-10-17	Novartis Ag	Variants of parathyroid hormone and its fragments
CN1070500C (zh) *	1993-07-13	2001-09-05	森德克斯(美国)股份有限公司	甲状旁腺激素类似物和甲状旁腺激素相关肽：合成和治疗骨质疏松症的用途

1996
- 1996-03-29 US US08/626,186 patent/US5723577A/en not_active Expired - Lifetime
- 1996-07-03 DE DE69630133T patent/DE69630133T2/de not_active Expired - Lifetime
- 1996-07-03 KR KR1020047006338A patent/KR100563600B1/ko not_active Expired - Fee Related
- 1996-07-03 DE DE69638025T patent/DE69638025D1/de not_active Expired - Lifetime
- 1996-07-03 DK DK96924355T patent/DK0847278T3/da active
- 1996-07-03 JP JP9505897A patent/JPH11509201A/ja active Pending
- 1996-07-03 EP EP03077383A patent/EP1405861B1/de not_active Expired - Lifetime
- 1996-07-03 AU AU64834/96A patent/AU707094B2/en not_active Expired
- 1996-07-03 SK SK31-98A patent/SK3198A3/sk unknown
- 1996-07-03 HU HU9901718A patent/HU226935B1/hu unknown
- 1996-07-03 KR KR1020047006340A patent/KR100563602B1/ko not_active Expired - Fee Related
- 1996-07-03 ES ES96924355T patent/ES2207680T3/es not_active Expired - Lifetime
- 1996-07-03 PT PT96924355T patent/PT847278E/pt unknown
- 1996-07-03 PL PL96325905A patent/PL186710B1/pl unknown
- 1996-07-03 AT AT96924355T patent/ATE250425T1/de active
- 1996-07-03 KR KR1020047006339A patent/KR100563601B1/ko not_active Expired - Fee Related
- 1996-07-03 NZ NZ312899A patent/NZ312899A/en not_active IP Right Cessation
- 1996-07-03 KR KR1020047006341A patent/KR100563112B1/ko not_active Expired - Lifetime
- 1996-07-03 CN CNB2004100054277A patent/CN100412091C/zh not_active Expired - Fee Related
- 1996-07-03 CN CNB961969261A patent/CN1247260C/zh not_active Expired - Fee Related
- 1996-07-03 CN CN201010150544A patent/CN101851288A/zh active Pending
- 1996-07-03 DK DK03077383T patent/DK1405861T3/da active
- 1996-07-03 AT AT03077383T patent/ATE442159T1/de active
- 1996-07-03 ES ES03077383T patent/ES2329233T3/es not_active Expired - Lifetime
- 1996-07-03 WO PCT/US1996/011292 patent/WO1997002834A1/en not_active Ceased
- 1996-07-03 EP EP96924355A patent/EP0847278B1/de not_active Expired - Lifetime
- 1996-07-03 PT PT03077383T patent/PT1405861E/pt unknown
- 1996-07-03 IL IL12283796A patent/IL122837A/en not_active IP Right Cessation
- 1996-07-03 KR KR10-1998-0700249A patent/KR100500853B1/ko not_active Expired - Fee Related
- 1996-07-11 TW TW085108390A patent/TW482766B/zh not_active IP Right Cessation
1998
- 1998-01-13 MX MX9800418A patent/MX9800418A/es active IP Right Grant
2003
- 2003-01-16 JP JP2003008027A patent/JP4008825B2/ja not_active Expired - Fee Related
2007
- 2007-07-02 JP JP2007174291A patent/JP2007302682A/ja active Pending

Also Published As

Publication number	Publication date
US5723577A (en)	1998-03-03
EP0847278A1 (de)	1998-06-17
KR20040053216A (ko)	2004-06-23
KR19990028947A (ko)	1999-04-15
ES2207680T3 (es)	2004-06-01
JP2007302682A (ja)	2007-11-22
KR100563112B1 (ko)	2006-03-27
JPH11509201A (ja)	1999-08-17
CN1199340A (zh)	1998-11-18
MX9800418A (es)	1998-09-30
HUP9901718A3 (en)	2000-10-30
KR20040053215A (ko)	2004-06-23
DK0847278T3 (da)	2003-12-22
IL122837A (en)	2002-11-10
EP1405861B1 (de)	2009-09-09
DE69638025D1 (de)	2009-10-22
CN1521189A (zh)	2004-08-18
EP1405861A3 (de)	2004-07-21
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DE69630133T2 (de)	2004-06-09
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