ATE251627T1 - Verfahren und kristallformen von 2- methylthienobenzodiazepinen - Google Patents

Verfahren und kristallformen von 2- methylthienobenzodiazepinen

Info

Publication number
ATE251627T1
ATE251627T1 AT00203573T AT00203573T ATE251627T1 AT E251627 T1 ATE251627 T1 AT E251627T1 AT 00203573 T AT00203573 T AT 00203573T AT 00203573 T AT00203573 T AT 00203573T AT E251627 T1 ATE251627 T1 AT E251627T1
Authority
AT
Austria
Prior art keywords
methylthienobezodiazepines
crystal forms
crystal
forms
Prior art date
Application number
AT00203573T
Other languages
English (en)
Inventor
Charles Arthur Bunnell
Barry Arnold Hendriksen
Samuel Dean Larsen
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23621056&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE251627(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE251627T1 publication Critical patent/ATE251627T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
AT00203573T 1995-03-24 1996-03-22 Verfahren und kristallformen von 2- methylthienobenzodiazepinen ATE251627T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40956695A 1995-03-24 1995-03-24

Publications (1)

Publication Number Publication Date
ATE251627T1 true ATE251627T1 (de) 2003-10-15

Family

ID=23621056

Family Applications (4)

Application Number Title Priority Date Filing Date
AT0902196A AT406771B (de) 1995-03-24 1996-03-22 Neue kristalline form von 2-methyl-4-(4-methyl- 1-piperazinyl)-1oh-thieno (2,3-b) (1,5)-benzodiazepin, verfahren zu deren herstellung, pharmazeutische mittel und deren verwendung
AT00203573T ATE251627T1 (de) 1995-03-24 1996-03-22 Verfahren und kristallformen von 2- methylthienobenzodiazepinen
AT96302000T ATE204280T1 (de) 1995-03-24 1996-03-22 Kristallformen eines thieno(2,3-b)(1, 5)benzodiazepinderivates und verfahren zu deren herstellung
AT03077455T ATE331719T1 (de) 1995-03-24 1996-03-22 Verwendung von kristallformen von 2- methylthienobenzodiazepinen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0902196A AT406771B (de) 1995-03-24 1996-03-22 Neue kristalline form von 2-methyl-4-(4-methyl- 1-piperazinyl)-1oh-thieno (2,3-b) (1,5)-benzodiazepin, verfahren zu deren herstellung, pharmazeutische mittel und deren verwendung

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT96302000T ATE204280T1 (de) 1995-03-24 1996-03-22 Kristallformen eines thieno(2,3-b)(1, 5)benzodiazepinderivates und verfahren zu deren herstellung
AT03077455T ATE331719T1 (de) 1995-03-24 1996-03-22 Verwendung von kristallformen von 2- methylthienobenzodiazepinen

Country Status (48)

Country Link
US (1) US5736541A (de)
EP (3) EP1095941B1 (de)
JP (1) JPH11502535A (de)
KR (1) KR100399688B1 (de)
CN (1) CN1065536C (de)
AP (1) AP828A (de)
AR (2) AR010448A1 (de)
AT (4) AT406771B (de)
AU (1) AU706471B2 (de)
BG (1) BG62619B1 (de)
BR (1) BR9607790A (de)
CA (1) CA2214005C (de)
CH (1) CH690579A5 (de)
CO (1) CO4650278A1 (de)
CZ (1) CZ292688B6 (de)
DE (4) DE69636313T2 (de)
DK (4) DK1095941T3 (de)
EA (1) EA000149B1 (de)
EE (1) EE03489B1 (de)
EG (1) EG23659A (de)
ES (3) ES2159346T3 (de)
FI (1) FI973750A0 (de)
GB (1) GB2313835B (de)
HU (1) HU224989B1 (de)
IL (1) IL117610A (de)
IS (1) IS1896B (de)
LT (1) LT4349B (de)
LU (1) LU90096B1 (de)
LV (1) LV12018B (de)
MY (1) MY114701A (de)
NO (1) NO314663B1 (de)
NZ (1) NZ306110A (de)
OA (1) OA10510A (de)
PA (1) PA8353701A1 (de)
PE (1) PE44897A1 (de)
PL (1) PL183723B1 (de)
PT (3) PT1445259E (de)
RO (1) RO118872B1 (de)
SE (1) SE9703205L (de)
SI (4) SI0733635T1 (de)
SK (1) SK284143B6 (de)
SV (1) SV1996000031A (de)
TR (1) TR199701017T1 (de)
TW (2) TW513432B (de)
UA (1) UA44765C2 (de)
WO (1) WO1996030375A1 (de)
YU (1) YU49478B (de)
ZA (2) ZA962342B (de)

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Also Published As

Publication number Publication date
DK1445259T3 (da) 2006-10-16
YU17796A (sh) 1999-03-04
SI1445259T1 (sl) 2006-10-31
JPH11502535A (ja) 1999-03-02
YU49478B (sh) 2006-05-25
EP1095941B1 (de) 2003-10-08
BR9607790A (pt) 1998-07-07
KR19980703188A (ko) 1998-10-15
DE69614426D1 (de) 2001-09-20
DE69614426T2 (de) 2002-05-23
RO118872B1 (ro) 2003-12-30
EP0733635B1 (de) 2001-08-16
AP828A (en) 2000-04-28
EA000149B1 (ru) 1998-10-29
PL322501A1 (en) 1998-02-02
PA8353701A1 (es) 1998-09-18
PT1445259E (pt) 2006-10-31
AU5427996A (en) 1996-10-16
EP0733635A1 (de) 1996-09-25
LT4349B (lt) 1998-05-25
IS4564A (is) 1997-09-22
EA199700262A1 (ru) 1998-02-26
TW513432B (en) 2002-12-11
DK0733635T3 (da) 2001-10-08
CN1065536C (zh) 2001-05-09
SI9620040B (sl) 2002-02-28
HU224989B1 (en) 2006-05-29
EP1445259B1 (de) 2006-06-28
FI973750A7 (fi) 1997-09-22
NO974365D0 (no) 1997-09-22
WO1996030375A1 (en) 1996-10-03
PT1095941E (pt) 2004-02-27
HUP9802824A2 (hu) 1999-06-28
CZ300097A3 (en) 1997-12-17
DK108997A (da) 1997-11-12
TR199701017T1 (xx) 1998-01-21
SI9620040A (sl) 1998-06-30
MX9707183A (es) 1997-11-29
FI973750L (fi) 1997-09-22
NO314663B1 (no) 2003-04-28
HUP9802824A3 (en) 2000-01-28
EE03489B1 (et) 2001-08-15
ES2159346T3 (es) 2001-10-01
SE9703205D0 (sv) 1997-09-05
EE9700232A (et) 1998-04-15
NZ306110A (en) 1998-09-24
SV1996000031A (es) 1998-03-27
DE69630324D1 (de) 2003-11-13
ES2266719T3 (es) 2007-03-01
BG101900A (en) 1999-03-31
CZ292688B6 (cs) 2003-11-12
BG62619B1 (bg) 2000-03-31
PT733635E (pt) 2001-12-28
ZA962342B (en) 1997-09-22
SI1095941T1 (en) 2003-12-31
IS1896B (is) 2003-10-20
PL183723B1 (pl) 2002-07-31
IL117610A0 (en) 1996-07-23
GB2313835B (en) 1998-09-16
SK121897A3 (en) 1998-03-04
SK284143B6 (sk) 2004-10-05
DE69636313D1 (de) 2006-08-10
DE19681286T1 (de) 1998-04-02
ATA902196A (de) 2000-01-15
FI973750A0 (fi) 1997-09-22
KR100399688B1 (ko) 2004-02-18
SI0733635T1 (en) 2002-06-30
PE44897A1 (es) 1997-10-22
LU90096B1 (fr) 1997-07-22
EP1445259A1 (de) 2004-08-11
ES2208220T3 (es) 2004-06-16
DK1095941T3 (da) 2004-02-16
NO974365L (no) 1997-09-22
SE9703205L (sv) 1997-09-05
CA2214005A1 (en) 1996-10-03
HK1013988A1 (en) 1999-09-17
EG23659A (en) 2007-03-26
TW442488B (en) 2001-06-23
CN1179160A (zh) 1998-04-15
ATE204280T1 (de) 2001-09-15
AP9701065A0 (en) 1997-10-31
AR010448A1 (es) 2000-06-28
US5736541A (en) 1998-04-07
AR002719A1 (es) 1998-04-29
CH690579A5 (de) 2000-10-31
ATE331719T1 (de) 2006-07-15
OA10510A (en) 2002-04-24
CO4650278A1 (es) 1998-09-03
MY114701A (en) 2002-12-31
AU706471B2 (en) 1999-06-17
ZA962344B (en) 1997-09-22
GB2313835A (en) 1997-12-10
CA2214005C (en) 2001-07-03
LV12018A (lv) 1998-04-20
AT406771B (de) 2000-08-25
DE69636313T2 (de) 2007-05-31
IL117610A (en) 2001-08-26
EP1095941A1 (de) 2001-05-02
GB9719819D0 (en) 1997-11-19
UA44765C2 (uk) 2002-03-15
DE69630324T2 (de) 2004-07-29
LT97148A (lt) 1998-01-26
LV12018B (en) 1998-09-20

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