ATE362985T1 - Apo-2 ligand - Google Patents
Apo-2 ligandInfo
- Publication number
- ATE362985T1 ATE362985T1 AT97903760T AT97903760T ATE362985T1 AT E362985 T1 ATE362985 T1 AT E362985T1 AT 97903760 T AT97903760 T AT 97903760T AT 97903760 T AT97903760 T AT 97903760T AT E362985 T1 ATE362985 T1 AT E362985T1
- Authority
- AT
- Austria
- Prior art keywords
- ligand
- apo
- cytokine
- antibodies
- induce
- Prior art date
Links
- 102000046283 TNF-Related Apoptosis-Inducing Ligand Human genes 0.000 title abstract 7
- 108700012411 TNFSF10 Proteins 0.000 title abstract 7
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
- Y10S930/144—Tumor necrosis factor
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/584,031 US6030945A (en) | 1996-01-09 | 1996-01-09 | Apo-2 ligand |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE362985T1 true ATE362985T1 (de) | 2007-06-15 |
Family
ID=24335618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97903760T ATE362985T1 (de) | 1996-01-09 | 1997-01-08 | Apo-2 ligand |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6030945A (de) |
| EP (3) | EP1734122A3 (de) |
| JP (4) | JP2001510321A (de) |
| AT (1) | ATE362985T1 (de) |
| AU (1) | AU729279B2 (de) |
| CA (2) | CA2241572C (de) |
| DE (1) | DE69737747T2 (de) |
| DK (1) | DK0873407T3 (de) |
| ES (1) | ES2287948T3 (de) |
| IL (3) | IL125168A0 (de) |
| PT (1) | PT873407E (de) |
| WO (1) | WO1997025428A1 (de) |
Families Citing this family (81)
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| US6998116B1 (en) | 1996-01-09 | 2006-02-14 | Genentech, Inc. | Apo-2 ligand |
| US20040048340A1 (en) * | 1996-03-14 | 2004-03-11 | Human Genome Sciences, Inc. | Apoptosis inducing molecule I |
| US6777217B1 (en) | 1996-03-26 | 2004-08-17 | President And Fellows Of Harvard College | Histone deacetylases, and uses related thereto |
| WO1997046686A2 (en) * | 1996-06-07 | 1997-12-11 | Amgen Inc. | Tumor necrosis factor-related polypeptide |
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| IL133122A0 (en) * | 1997-06-18 | 2001-03-19 | Genentech Inc | Apo-2dcr polypeptides |
| US6346388B1 (en) | 1997-08-13 | 2002-02-12 | Smithkline Beecham Corporation | Method of identifying agonist and antagonists for tumor necrosis related receptors TR1 and TR2 |
| JP4303883B2 (ja) | 1997-09-18 | 2009-07-29 | ジェネンテック・インコーポレーテッド | DcR3ポリペプチドというTNFR相同体 |
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| JP2002508962A (ja) * | 1998-01-15 | 2002-03-26 | ジェネンテク・インコーポレイテッド | Apo−2リガンド |
| AU2338299A (en) | 1998-01-26 | 1999-08-09 | Genentech Inc. | Antibodies to death receptor 4 (dr4) and uses thereof |
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| EP1941905A1 (de) | 1998-03-27 | 2008-07-09 | Genentech, Inc. | APO-2 Liganden-Anti-HER-2-Antikörper-Synergismus |
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| CA2365913C (en) | 1999-04-12 | 2015-03-03 | Genentech, Inc. | Tumor necrosis factor receptor homologs and nucleic acids encoding the same |
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| ATE330972T1 (de) * | 1999-06-09 | 2006-07-15 | Genentech Inc | Apo-2l rezeptor-agonist und cpt-11 synergie- effekt |
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-
1996
- 1996-01-09 US US08/584,031 patent/US6030945A/en not_active Expired - Lifetime
-
1997
- 1997-01-08 AT AT97903760T patent/ATE362985T1/de active
- 1997-01-08 JP JP52536997A patent/JP2001510321A/ja not_active Withdrawn
- 1997-01-08 AU AU18248/97A patent/AU729279B2/en not_active Expired
- 1997-01-08 IL IL12516897A patent/IL125168A0/xx unknown
- 1997-01-08 CA CA002241572A patent/CA2241572C/en not_active Expired - Lifetime
- 1997-01-08 EP EP06013720A patent/EP1734122A3/de not_active Withdrawn
- 1997-01-08 DK DK97903760T patent/DK0873407T3/da active
- 1997-01-08 CA CA002666263A patent/CA2666263A1/en not_active Abandoned
- 1997-01-08 ES ES97903760T patent/ES2287948T3/es not_active Expired - Lifetime
- 1997-01-08 WO PCT/US1997/000272 patent/WO1997025428A1/en not_active Ceased
- 1997-01-08 EP EP07022045A patent/EP1889915A1/de not_active Withdrawn
- 1997-01-08 EP EP97903760A patent/EP0873407B1/de not_active Expired - Lifetime
- 1997-01-08 PT PT97903760T patent/PT873407E/pt unknown
- 1997-01-08 DE DE69737747T patent/DE69737747T2/de not_active Expired - Lifetime
-
1998
- 1998-06-30 IL IL125168A patent/IL125168A/en not_active IP Right Cessation
-
2004
- 2004-11-11 JP JP2004328142A patent/JP2005237370A/ja active Pending
-
2006
- 2006-12-20 JP JP2006343397A patent/JP2007169280A/ja not_active Withdrawn
-
2008
- 2008-07-01 JP JP2008172349A patent/JP2008308502A/ja active Pending
- 2008-08-28 IL IL193752A patent/IL193752A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2241572A1 (en) | 1997-07-17 |
| EP1889915A1 (de) | 2008-02-20 |
| US6030945A (en) | 2000-02-29 |
| IL125168A0 (en) | 1999-01-26 |
| JP2008308502A (ja) | 2008-12-25 |
| EP1734122A2 (de) | 2006-12-20 |
| JP2005237370A (ja) | 2005-09-08 |
| AU729279B2 (en) | 2001-02-01 |
| EP1734122A3 (de) | 2007-07-11 |
| WO1997025428A1 (en) | 1997-07-17 |
| ES2287948T3 (es) | 2007-12-16 |
| DK0873407T3 (da) | 2007-09-24 |
| DE69737747T2 (de) | 2008-02-14 |
| DE69737747D1 (de) | 2007-07-05 |
| PT873407E (pt) | 2007-09-04 |
| CA2666263A1 (en) | 1997-07-17 |
| AU1824897A (en) | 1997-08-01 |
| HK1018961A1 (en) | 2000-01-14 |
| IL125168A (en) | 2011-04-28 |
| CA2241572C (en) | 2009-08-11 |
| EP0873407A1 (de) | 1998-10-28 |
| JP2001510321A (ja) | 2001-07-31 |
| IL193752A0 (en) | 2011-08-01 |
| EP0873407B1 (de) | 2007-05-23 |
| JP2007169280A (ja) | 2007-07-05 |
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