ATE373466T1 - Lipidträgerzusammensetzungen und verfahren zur verbesserten wirkstoffzurückhaltung - Google Patents

Lipidträgerzusammensetzungen und verfahren zur verbesserten wirkstoffzurückhaltung

Info

Publication number
ATE373466T1
ATE373466T1 AT02774211T AT02774211T ATE373466T1 AT E373466 T1 ATE373466 T1 AT E373466T1 AT 02774211 T AT02774211 T AT 02774211T AT 02774211 T AT02774211 T AT 02774211T AT E373466 T1 ATE373466 T1 AT E373466T1
Authority
AT
Austria
Prior art keywords
methods
lipid carrier
carrier compositions
improved active
active retention
Prior art date
Application number
AT02774211T
Other languages
English (en)
Inventor
Murray Webb
Paul Tardi
Original Assignee
Celator Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celator Pharmaceuticals Inc filed Critical Celator Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE373466T1 publication Critical patent/ATE373466T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT02774211T 2001-11-13 2002-11-13 Lipidträgerzusammensetzungen und verfahren zur verbesserten wirkstoffzurückhaltung ATE373466T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33124901P 2001-11-13 2001-11-13

Publications (1)

Publication Number Publication Date
ATE373466T1 true ATE373466T1 (de) 2007-10-15

Family

ID=23293193

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02774211T ATE373466T1 (de) 2001-11-13 2002-11-13 Lipidträgerzusammensetzungen und verfahren zur verbesserten wirkstoffzurückhaltung

Country Status (7)

Country Link
US (1) US20050118249A1 (de)
EP (1) EP1448165B1 (de)
AT (1) ATE373466T1 (de)
AU (1) AU2002340670A1 (de)
DE (1) DE60222580T2 (de)
ES (1) ES2290333T3 (de)
WO (1) WO2003041682A2 (de)

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US20060222694A1 (en) * 2003-06-27 2006-10-05 Oh Choon K Stabilized topotecan liposomal composition and methods
WO2005094790A1 (es) * 2004-04-02 2005-10-13 Italfarmaco, S.A. Formulaciones liposomales
CN1960729B (zh) 2004-06-01 2012-04-11 泰尔茂株式会社 伊立替康制剂
US20090148506A1 (en) * 2005-12-22 2009-06-11 Awa Dicko Liposomal formulations comprising secondary and tertiary amines and methods for preparing thereof
WO2009059449A1 (en) * 2007-11-05 2009-05-14 Celsion Corporation Novel thermosensitive liposomes containing therapeutic agents
EP2123258A1 (de) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomen zur Arzneimittelverabreichung
EP2415464B1 (de) * 2009-03-30 2017-05-10 Eisai R&D Management Co., Ltd. Verfahren zur herstellung einer liposomenzusammensetzung
HRP20161157T1 (hr) 2009-03-30 2016-11-18 Eisai R&D Management Co., Ltd. Liposomski pripravak
DK177532B1 (en) * 2009-09-17 2013-09-08 Bio Bedst Aps Medical use of sPLA2 hydrolysable liposomes
KR20140092226A (ko) 2010-12-14 2014-07-23 테크니칼 유니버시티 오브 덴마크 나노입자 조성물에서 방사성 핵종의 포집
KR102284689B1 (ko) 2011-10-21 2021-08-02 셀라토 파마슈티칼즈, 인코포레이티드 동결건조된 리포좀
WO2014047116A1 (en) * 2012-09-18 2014-03-27 Comfort Care For Animals Llc Encapsulating liposomes
US10039716B2 (en) 2013-03-13 2018-08-07 Mallinckrodt Llc Liposomal cisplatin compositions for cancer therapy
US9993427B2 (en) * 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
MX381655B (es) * 2015-05-04 2025-03-13 Versantis AG Metodo para preparar vesiculas con gradiente de ph de transmembrana.
WO2017188350A1 (ja) 2016-04-28 2017-11-02 エーザイ・アール・アンド・ディー・マネジメント株式会社 腫瘍の成長を抑制する方法
US11083705B2 (en) 2019-07-26 2021-08-10 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
US12036204B2 (en) 2019-07-26 2024-07-16 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor

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Also Published As

Publication number Publication date
AU2002340670A1 (en) 2003-05-26
EP1448165B1 (de) 2007-09-19
WO2003041682A3 (en) 2003-09-18
WO2003041682A2 (en) 2003-05-22
DE60222580D1 (de) 2007-10-31
EP1448165A2 (de) 2004-08-25
ES2290333T3 (es) 2008-02-16
DE60222580T2 (de) 2008-06-12
US20050118249A1 (en) 2005-06-02

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