ATE425152T1 - Aminocarbonylderivate als histone-deacetylase- inhibitoren - Google Patents

Aminocarbonylderivate als histone-deacetylase- inhibitoren

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Publication number
ATE425152T1
ATE425152T1 AT03708214T AT03708214T ATE425152T1 AT E425152 T1 ATE425152 T1 AT E425152T1 AT 03708214 T AT03708214 T AT 03708214T AT 03708214 T AT03708214 T AT 03708214T AT E425152 T1 ATE425152 T1 AT E425152T1
Authority
AT
Austria
Prior art keywords
histone deacetylase
deacetylase inhibitors
aminocarbonyl derivatives
aminocarbonyl
derivatives
Prior art date
Application number
AT03708214T
Other languages
English (en)
Inventor
Emelen Kristof Van
Winter Hans L J De
Alexey Dyatkin
Marc G C Verdonck
Lieven Meerpoel
Heusden Jimmy Arnold Viviane Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE425152T1 publication Critical patent/ATE425152T1/de

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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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ZA200407233B (en) 2005-10-06
CA2476065C (en) 2012-07-24
EP1485353B1 (de) 2011-08-24
UA78033C2 (en) 2007-02-15
JP4644428B2 (ja) 2011-03-02
EA008245B1 (ru) 2007-04-27
CA2475764C (en) 2011-05-31
CA2476065A1 (en) 2003-09-18
BR0307624A (pt) 2005-01-11
DK1485353T3 (da) 2011-11-28
IL164003A0 (en) 2005-12-18
AU2003218736B2 (en) 2009-01-08
UA78032C2 (en) 2007-02-15
DE60326549D1 (en) 2009-04-23
EP1485370B1 (de) 2009-03-04
JP4472353B2 (ja) 2010-06-02
HRP20040799A2 (en) 2005-04-30
IL164007A0 (en) 2005-12-18
ATE424395T1 (de) 2009-03-15
IL164006A (en) 2010-11-30
JP2005525379A (ja) 2005-08-25
HK1078473A1 (en) 2006-03-17
US9150560B2 (en) 2015-10-06
UA77263C2 (en) 2006-11-15
WO2003076421A1 (en) 2003-09-18
EP1485099B1 (de) 2010-07-07
BR0308081A (pt) 2004-12-21
JP2005525381A (ja) 2005-08-25
US20100048588A1 (en) 2010-02-25
CN1642551B (zh) 2011-09-14
CA2476583C (en) 2011-07-05
NO20044194L (no) 2004-10-01
IL164007A (en) 2011-03-31
IL164005A0 (en) 2005-12-18
KR20040090979A (ko) 2004-10-27
US20090170836A1 (en) 2009-07-02
US8455498B2 (en) 2013-06-04
US20050107384A1 (en) 2005-05-19
US20120252790A1 (en) 2012-10-04
EA200401201A1 (ru) 2005-02-24
AU2003218737B2 (en) 2008-04-10

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