ATE427953T1 - Fondaparinux- natrium zusammenstellung von hoher reinheit - Google Patents

Fondaparinux- natrium zusammenstellung von hoher reinheit

Info

Publication number: ATE427953T1
Authority: AT; Austria
Prior art keywords: fondaparinux; high purity; sodium composition; sodium; composition
Prior art date: 2003-02-27

Application number

AT04710418T

Other languages

English (en)

Inventor

Jean-Francois Branellec

Christian Morello

Pierre Potier

Patrick Trouilleux

Petrus Marcus F M Bastiaansen

Henricus Claassen

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-02-27

Filing date

2004-02-12

Publication date

2009-04-15

2004-02-12 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2009-04-15 Application granted granted Critical

2009-04-15 Publication of ATE427953T1 publication Critical patent/ATE427953T1/de

Links

XEKSTYNIJLDDAZ-JASSWCPGSA-F fondaparinux sodium Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].O[C@@H]1[C@@H](NS([O-])(=O)=O)[C@@H](OC)O[C@H](COS([O-])(=O)=O)[C@H]1O[C@H]1[C@H](OS([O-])(=O)=O)[C@@H](O)[C@H](O[C@@H]2[C@@H]([C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O[C@@H]4[C@@H]([C@@H](O)[C@H](O)[C@@H](COS([O-])(=O)=O)O4)NS([O-])(=O)=O)[C@H](O3)C(O)=O)O)[C@@H](COS([O-])(=O)=O)O2)NS([O-])(=O)=O)[C@H](C(O)=O)O1 XEKSTYNIJLDDAZ-JASSWCPGSA-F 0.000 title 1
229960003661 fondaparinux sodium Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT04710418T 2003-02-27 2004-02-12 Fondaparinux- natrium zusammenstellung von hoher reinheit ATE427953T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US37526803A	2003-02-27	2003-02-27

Publications (1)

Publication Number	Publication Date
ATE427953T1 true ATE427953T1 (de)	2009-04-15

Family

ID=32961215

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04710418T ATE427953T1 (de)	2003-02-27	2004-02-12	Fondaparinux- natrium zusammenstellung von hoher reinheit

Country Status (13)

Country	Link
US (1)	US20050020536A1 (de)
EP (1)	EP1625135B1 (de)
JP (1)	JP4594298B2 (de)
AR (1)	AR044200A1 (de)
AT (1)	ATE427953T1 (de)
CY (1)	CY1109168T1 (de)
DE (1)	DE602004020459D1 (de)
DK (1)	DK1625135T3 (de)
ES (1)	ES2322464T3 (de)
PT (1)	PT1625135E (de)
SI (1)	SI1625135T1 (de)
TW (1)	TWI335224B (de)
WO (1)	WO2004078105A2 (de)

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US20040171819A1 (en)	2002-10-10	2004-09-02	Aventis Pharma S.A.	Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
AU2006244563B2 (en) *	2005-05-05	2011-07-21	Nyse Group, Inc.	Anti-internalization order modifier
US7635773B2 (en)	2008-04-28	2009-12-22	Cydex Pharmaceuticals, Inc.	Sulfoalkyl ether cyclodextrin compositions
WO2010132616A1 (en) *	2009-05-12	2010-11-18	Rsa Protective Technologies, Llc	Surface mount vehicle anti-ram security systems
CA2777099C (en) *	2009-07-31	2018-03-27	Reliable Biopharmaceutical Corporation	Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
US8420790B2 (en)	2009-10-30	2013-04-16	Reliable Biopharmaceutical Corporation	Efficient and scalable process for the manufacture of Fondaparinux sodium
US20130005954A1 (en) *	2011-06-28	2013-01-03	Apicore, Llc	Process for preparing heparinoids and intermediates useful in the synthesis thereof
CN102659859B (zh) *	2012-04-11	2014-12-10	苏州纳微科技有限公司	单分散聚甲基丙烯酸酯离子交换层析介质在磺达肝癸钠柱层析纯化中的应用
CN103570774B (zh) *	2012-08-07	2017-08-25	博瑞生物医药（苏州）股份有限公司	一种戊糖化合物的纯化方法
KR102112119B1 (ko)	2012-10-22	2020-05-19	사이덱스 파마슈티칼스, 인크.	알킬화된 시클로덱스트린 조성물 및 이의 제조 및 사용 방법
CN103864862B (zh) *	2012-12-14	2017-10-17	博瑞生物医药（苏州）股份有限公司	一种戊糖化合物的纯化方法
US9346844B2 (en)	2013-07-25	2016-05-24	Scinopharm Taiwan, Ltd.	Process for the production of fondaparinux sodium
EP3024840B1 (de) *	2013-07-25	2019-10-02	ScinoPharm Taiwan, Ltd.	Verfahren zur herstellung von fondaparinux-natrium
US10072039B2 (en)	2013-07-25	2018-09-11	Scinopharm Taiwan, Ltd.	Process for the production of Fondaparinux sodium
CN103992364B (zh) *	2014-03-25	2016-08-10	南京天翔医药科技有限公司	一种磺达肝癸钠的分离提取方法
CN103965269B (zh) *	2014-04-16	2018-05-04	杭州华东医药集团新药研究院有限公司	低水分高纯度的磺达肝癸钠及其制备方法
US9873712B2 (en) *	2014-10-03	2018-01-23	Amphastar Pharmaceuticals, Inc.	Method of purifying idraparinux sodium
US10688249B2 (en) *	2015-06-11	2020-06-23	Virchow Biotech Pvt. Ltd.	Multiple dose pharmaceutical compositions containing heparin and/or heparin-like compounds and devices and methods for delivering the same
CN104910217B (zh) *	2015-06-19	2018-04-17	天津红日药业股份有限公司	用于磺达肝癸钠质量控制的参比化合物
CN105037452B (zh) *	2015-06-19	2018-10-09	天津红日药业股份有限公司	一种快速制备高纯度磺达肝癸钠的精制方法
CN107501359B (zh) *	2017-08-24	2020-07-31	深圳市海滨制药有限公司	一种磺达肝癸钠杂质化合物及其制备方法与应用
CN114478663B (zh) *	2020-11-12	2023-12-01	杭州中美华东制药有限公司	一种磺达肝癸钠杂质的制备方法
CN114591379A (zh) *	2021-12-30	2022-06-07	淮北师范大学	一种磺达肝癸钠甲酰化杂质的制备方法

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US4242501A (en) *	1979-08-08	1980-12-30	American Cyanamid Company	Purification of pneumococcal capsular polysaccharides
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DE3118588C2 (de) *	1981-05-11	1983-07-07	Luitpold-Werk, Chemisch-Pharmazeutische Fabrik, 8000 München	Verfahren zur Herstellung eines injizierbaren hochreinen Chondroitinpolysulfates, hiernach erhältliches Produkt und pharmazeutische Zusammensetzung
JPS5899497A (ja) *	1981-11-27	1983-06-13	Snow Brand Milk Prod Co Ltd	新規なオリゴ糖、その製造法及びビフイドバクテリウム菌の増殖促進剤
JPS60102196A (ja) *	1983-11-07	1985-06-06	Daicel Chem Ind Ltd	粗グリコシドの精製処理方法
US4686102A (en) *	1984-04-12	1987-08-11	American Cyanamid Company	Multivalent pneumococcal vaccine and preparation thereof
JPS61118336A (ja) *	1984-11-13	1986-06-05	Yonezawa Kagaku Kogyo Kk	ペンタクロルフエノ−ル及びその誘導体の精製法
JPH0673442B2 (ja) *	1986-03-13	1994-09-21	明治製菓株式会社	食品の老化防止方法
SE453394B (sv) *	1986-07-07	1988-02-01	Pharmacia Ab	Forfarande for framstellning av sulfaterade polysackarider genom anvendning av ett reducerande medel for sulfateringsreaktionen
JPS6398395A (ja) *	1986-10-16	1988-04-28	Katakura Chitsukarin Kk	キトサンオリゴ糖の製造法
US5756721A (en) *	1991-01-16	1998-05-26	National Starch And Chemical Investment Holding Corporation	Purification of polysaccharides
US5569756A (en) *	1995-03-21	1996-10-29	American Maize-Products Company	Purification of chemically modified cyclodextrins
DE19543052A1 (de) *	1995-11-06	1997-05-07	Schering Ag	Verfahren zur Herstellung und Reinigung von Fludarabin-Phosphat und die Verwendung von sauren Ionenaustauschern im Verfahren
EP1235783B1 (de) *	1999-08-30	2004-09-29	Mossi & Ghisolfi International S.A.	Verfahren zur trennung des dikaliumsalzes der naphthalenedicarbonsäure mittels betten von aktivierter kohle

2004
- 2004-02-12 JP JP2006505669A patent/JP4594298B2/ja not_active Expired - Fee Related
- 2004-02-12 DE DE602004020459T patent/DE602004020459D1/de not_active Expired - Lifetime
- 2004-02-12 PT PT04710418T patent/PT1625135E/pt unknown
- 2004-02-12 WO PCT/FR2004/000314 patent/WO2004078105A2/fr not_active Ceased
- 2004-02-12 SI SI200431107T patent/SI1625135T1/sl unknown
- 2004-02-12 DK DK04710418T patent/DK1625135T3/da active
- 2004-02-12 EP EP04710418A patent/EP1625135B1/de not_active Expired - Lifetime
- 2004-02-12 AT AT04710418T patent/ATE427953T1/de active
- 2004-02-12 ES ES04710418T patent/ES2322464T3/es not_active Expired - Lifetime
- 2004-02-19 AR ARP040100513A patent/AR044200A1/es not_active Application Discontinuation
- 2004-02-19 TW TW093104096A patent/TWI335224B/zh not_active IP Right Cessation
- 2004-06-30 US US10/881,250 patent/US20050020536A1/en not_active Abandoned
2009
- 2009-06-18 CY CY20091100645T patent/CY1109168T1/el unknown

Also Published As

Publication number	Publication date
WO2004078105A2 (fr)	2004-09-16
AR044200A1 (es)	2005-09-07
DK1625135T3 (da)	2009-06-22
EP1625135A2 (de)	2006-02-15
JP4594298B2 (ja)	2010-12-08
ES2322464T3 (es)	2009-06-22
DE602004020459D1 (de)	2009-05-20
JP2006519246A (ja)	2006-08-24
CY1109168T1 (el)	2014-07-02
TW200501965A (en)	2005-01-16
PT1625135E (pt)	2009-07-10
TWI335224B (en)	2011-01-01
US20050020536A1 (en)	2005-01-27
EP1625135B1 (de)	2009-04-08
WO2004078105A3 (fr)	2004-10-28
SI1625135T1 (sl)	2009-08-31
HK1087719A1 (zh)	2006-10-20

Legal Events

Date

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Title

Description

2009-10-15

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Publication	Publication Date	Title
ATE427953T1 (de)	2009-04-15	Fondaparinux- natrium zusammenstellung von hoher reinheit
CY2015015I1 (el)	2020-05-29	Παραγωγη τιακουμυκινης
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SE0301569D0 (sv)	2003-05-27	Novel compounds
DE60334165D1 (de)	2010-10-21	Härtbare Zusammensetzung
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DK1522539T3 (da)	2007-05-07	Krystallinsk komposition indeholdende excitalopram
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