ATE449763T1 - 1h-indazolverbindungen die jnk hemmen - Google Patents
1h-indazolverbindungen die jnk hemmenInfo
- Publication number
- ATE449763T1 ATE449763T1 AT02724612T AT02724612T ATE449763T1 AT E449763 T1 ATE449763 T1 AT E449763T1 AT 02724612 T AT02724612 T AT 02724612T AT 02724612 T AT02724612 T AT 02724612T AT E449763 T1 ATE449763 T1 AT E449763T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- group etc
- single bond
- cyclic hydrocarbon
- provides
- Prior art date
Links
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical class C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title 1
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- -1 1H-indazole compound Chemical class 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Paper (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001116521 | 2001-04-16 | ||
| PCT/JP2002/003735 WO2002083648A1 (fr) | 2001-04-16 | 2002-04-15 | Nouveau compose a base de 1h-indazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449763T1 true ATE449763T1 (de) | 2009-12-15 |
Family
ID=18967246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02724612T ATE449763T1 (de) | 2001-04-16 | 2002-04-15 | 1h-indazolverbindungen die jnk hemmen |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US6982274B2 (de) |
| EP (1) | EP1380576B1 (de) |
| JP (1) | JP4535680B2 (de) |
| KR (1) | KR20040007497A (de) |
| CN (1) | CN1300116C (de) |
| AT (1) | ATE449763T1 (de) |
| AU (1) | AU2002255263B2 (de) |
| CA (1) | CA2440842A1 (de) |
| DE (1) | DE60234510D1 (de) |
| WO (1) | WO2002083648A1 (de) |
Families Citing this family (126)
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| BR0313396A (pt) | 2002-08-12 | 2005-06-28 | Sugen Inc | 3-pirrolil-piridopirazóis e 3-pirrolil-indazóis, como inibidores de quinase |
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-
2002
- 2002-04-15 AU AU2002255263A patent/AU2002255263B2/en not_active Ceased
- 2002-04-15 KR KR10-2003-7013494A patent/KR20040007497A/ko not_active Ceased
- 2002-04-15 EP EP02724612A patent/EP1380576B1/de not_active Expired - Lifetime
- 2002-04-15 CN CNB028082907A patent/CN1300116C/zh not_active Expired - Fee Related
- 2002-04-15 JP JP2002581404A patent/JP4535680B2/ja not_active Expired - Fee Related
- 2002-04-15 DE DE60234510T patent/DE60234510D1/de not_active Expired - Lifetime
- 2002-04-15 AT AT02724612T patent/ATE449763T1/de not_active IP Right Cessation
- 2002-04-15 WO PCT/JP2002/003735 patent/WO2002083648A1/ja not_active Ceased
- 2002-04-15 US US10/469,399 patent/US6982274B2/en not_active Expired - Fee Related
- 2002-04-15 CA CA002440842A patent/CA2440842A1/en not_active Abandoned
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2005
- 2005-08-12 US US11/202,234 patent/US7541376B2/en not_active Expired - Fee Related
-
2009
- 2009-04-20 US US12/426,818 patent/US7776890B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1380576A4 (de) | 2005-02-16 |
| US6982274B2 (en) | 2006-01-03 |
| CA2440842A1 (en) | 2002-10-24 |
| US20090203691A1 (en) | 2009-08-13 |
| WO2002083648A1 (fr) | 2002-10-24 |
| US20050282880A1 (en) | 2005-12-22 |
| EP1380576A1 (de) | 2004-01-14 |
| CN1300116C (zh) | 2007-02-14 |
| US7541376B2 (en) | 2009-06-02 |
| US7776890B2 (en) | 2010-08-17 |
| JP4535680B2 (ja) | 2010-09-01 |
| AU2002255263B2 (en) | 2006-12-14 |
| CN1512987A (zh) | 2004-07-14 |
| US20040127538A1 (en) | 2004-07-01 |
| JPWO2002083648A1 (ja) | 2004-08-05 |
| KR20040007497A (ko) | 2004-01-24 |
| EP1380576B1 (de) | 2009-11-25 |
| DE60234510D1 (de) | 2010-01-07 |
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