ATE92959T1 - Herstellung von chimaeren antikoerpern. - Google Patents

Herstellung von chimaeren antikoerpern.

Info

Publication number
ATE92959T1
ATE92959T1 AT85904274T AT85904274T ATE92959T1 AT E92959 T1 ATE92959 T1 AT E92959T1 AT 85904274 T AT85904274 T AT 85904274T AT 85904274 T AT85904274 T AT 85904274T AT E92959 T1 ATE92959 T1 AT E92959T1
Authority
AT
Austria
Prior art keywords
encodes
production
molecule
preparing
variable region
Prior art date
Application number
AT85904274T
Other languages
English (en)
Inventor
Michael Samuel Neuberger
Terence Howard Rabbitts
Original Assignee
Celltech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10566192&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE92959(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celltech Ltd filed Critical Celltech Ltd
Application granted granted Critical
Publication of ATE92959T1 publication Critical patent/ATE92959T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT85904274T 1984-09-03 1985-09-03 Herstellung von chimaeren antikoerpern. ATE92959T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB848422238A GB8422238D0 (en) 1984-09-03 1984-09-03 Chimeric proteins
PCT/GB1985/000392 WO1986001533A1 (en) 1984-09-03 1985-09-03 Production of chimeric antibodies
EP85904274A EP0194276B2 (de) 1984-09-03 1985-09-03 Herstellung von chimären antikörpern

Publications (1)

Publication Number Publication Date
ATE92959T1 true ATE92959T1 (de) 1993-08-15

Family

ID=10566192

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85904274T ATE92959T1 (de) 1984-09-03 1985-09-03 Herstellung von chimaeren antikoerpern.

Country Status (6)

Country Link
EP (1) EP0194276B2 (de)
JP (2) JP2714786B2 (de)
AT (1) ATE92959T1 (de)
DE (1) DE3587524T3 (de)
GB (2) GB8422238D0 (de)
WO (1) WO1986001533A1 (de)

Families Citing this family (1220)

* Cited by examiner, † Cited by third party
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JPS62500352A (ja) 1987-02-19
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GB2177096B (en) 1989-05-17
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DE3587524T2 (de) 1994-01-20
DE3587524D1 (de) 1993-09-16
GB2177096A (en) 1987-01-14
WO1986001533A1 (en) 1986-03-13
JP2865645B2 (ja) 1999-03-08
EP0194276A1 (de) 1986-09-17
GB8608827D0 (en) 1986-05-14
EP0194276B1 (de) 1993-08-11
DE3587524T3 (de) 2002-06-20

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