BE903540A - Formulations a liberation progressive, procede pour leur preparation et compositions les renfermant - Google Patents

Formulations a liberation progressive, procede pour leur preparation et compositions les renfermant

Info

Publication number
BE903540A
BE903540A BE0/215788A BE215788A BE903540A BE 903540 A BE903540 A BE 903540A BE 0/215788 A BE0/215788 A BE 0/215788A BE 215788 A BE215788 A BE 215788A BE 903540 A BE903540 A BE 903540A
Authority
BE
Belgium
Prior art keywords
progressive release
microparticles
preparation
compositions containing
release formulations
Prior art date
Application number
BE0/215788A
Other languages
English (en)
Original Assignee
Elan Corp Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Corp Plc filed Critical Elan Corp Plc
Publication of BE903540A publication Critical patent/BE903540A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/18—Chewing gum characterised by shape, structure or physical form, e.g. aerated products
    • A23G4/20—Composite products, e.g. centre-filled, multi-layer, laminated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

Poudre à libération progressive contenant des microparticules distinctes, utile dans des compositions comestibles ou pharmaceutiques et autres compositions à libération progressive. Les microparticules ont une taille moyenne dans la gamme de 0,1 à 125 mu et sont chacune sous forme d'une micromatrice d'un ingrédient actif distribué uniformément dans au moins un polymère non toxique. Les microparticules ont une libération prédéterminée de l'ingrédient actif lorsque le taux de dissolution en est mesuré selon la Paddle Method de l'US Pharmacopoeia XX à 37 degrés C et à 75 tr/mn.
BE0/215788A 1984-10-30 1985-10-29 Formulations a liberation progressive, procede pour leur preparation et compositions les renfermant BE903540A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE278884A IE58110B1 (en) 1984-10-30 1984-10-30 Controlled release powder and process for its preparation

Publications (1)

Publication Number Publication Date
BE903540A true BE903540A (fr) 1986-02-17

Family

ID=11036490

Family Applications (2)

Application Number Title Priority Date Filing Date
BE0/215789A BE903541Q (fr) 1984-10-30 1985-10-29 Procede de fabrication d'un latex coagule de configuration spherique
BE0/215788A BE903540A (fr) 1984-10-30 1985-10-29 Formulations a liberation progressive, procede pour leur preparation et compositions les renfermant

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BE0/215789A BE903541Q (fr) 1984-10-30 1985-10-29 Procede de fabrication d'un latex coagule de configuration spherique

Country Status (16)

Country Link
US (3) US4952402A (fr)
JP (1) JP2820239B2 (fr)
AU (1) AU579415B2 (fr)
BE (2) BE903541Q (fr)
CA (1) CA1268051A (fr)
CH (1) CH669728A5 (fr)
DE (1) DE3538429C2 (fr)
DK (1) DK175329B1 (fr)
FR (1) FR2572282B1 (fr)
GB (1) GB2166651B (fr)
HK (1) HK44091A (fr)
IE (1) IE58110B1 (fr)
IT (1) IT1185831B (fr)
NL (1) NL193582C (fr)
SE (1) SE8505099L (fr)
ZA (1) ZA858300B (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4867987A (en) * 1986-06-25 1989-09-19 Mepha Ag Pharmaceutical product for the sustained release of ibuprofen
US4992277A (en) * 1989-08-25 1991-02-12 Schering Corporation Immediate release diltiazem formulation
US5000962A (en) * 1989-08-25 1991-03-19 Schering Corporation Long acting diltiazem formulation
WO1995001788A1 (fr) * 1993-07-09 1995-01-19 Trustees Of Tufts College Procedes et articles d'administration de medicament dans la cavite buccale
EP0601508A3 (en) * 1992-12-11 1995-10-25 Recordati Chem Pharm Liquid-suspension controlled-release pharmaceutical composition.
US5527545A (en) * 1989-09-18 1996-06-18 Recordati S.A. Chemical And Pharmaceutical Company Liquid-suspension controlled-release pharmaceutical composition

Families Citing this family (1358)

* Cited by examiner, † Cited by third party
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US5288498A (en) * 1985-05-01 1994-02-22 University Of Utah Research Foundation Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments
IT1178511B (it) * 1984-09-14 1987-09-09 Pharmatec Spa Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
JPS63500175A (ja) * 1985-05-22 1988-01-21 リポソ−ム　テクノロジ−，インコ−ポレイテツド リポソ−ム吸入法および吸入システム
US5286489A (en) * 1985-08-26 1994-02-15 The Procter & Gamble Company Taste masking compositions
CA1311686C (fr) * 1986-06-25 1992-12-22 John Weldon Shell Systeme d'administration de medicaments bioerodables a degagement controle
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US5211954A (en) * 1986-09-23 1993-05-18 Sandoz Ltd. Low dose temazepam
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US4992277A (en) * 1989-08-25 1991-02-12 Schering Corporation Immediate release diltiazem formulation
US5000962A (en) * 1989-08-25 1991-03-19 Schering Corporation Long acting diltiazem formulation
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HK44091A (en) 1991-06-14
DK495585A (da) 1986-05-01
US4940588A (en) 1990-07-10
US5354556A (en) 1994-10-11
CA1268051A (fr) 1990-04-24
FR2572282B1 (fr) 1989-03-31
US4952402A (en) 1990-08-28
CH669728A5 (fr) 1989-04-14
GB2166651A (en) 1986-05-14
DK175329B1 (da) 2004-08-23
IE58110B1 (en) 1993-07-14
NL8502951A (nl) 1986-05-16
FR2572282A1 (fr) 1986-05-02
GB8526591D0 (en) 1985-12-04
IT8567913A0 (it) 1985-10-29
DE3538429C2 (de) 1996-10-24
SE8505099L (sv) 1986-05-01
AU4916185A (en) 1986-05-08
ZA858300B (en) 1986-07-30
BE903541Q (fr) 1986-02-17
JP2820239B2 (ja) 1998-11-05
AU579415B2 (en) 1988-11-24
SE8505099D0 (sv) 1985-10-29
JPS61109711A (ja) 1986-05-28
GB2166651B (en) 1988-11-16
NL193582C (nl) 2000-03-02
IT1185831B (it) 1987-11-18
DK495585D0 (da) 1985-10-29
NL193582B (nl) 1999-11-01
DE3538429A1 (de) 1986-04-30

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