BRPI0107679B8 - composição compreendendo vesículas de membrana externa do grupo sérico b de neisseria meningitidis e um componente inorgânico e uso da mesma - Google Patents

composição compreendendo vesículas de membrana externa do grupo sérico b de neisseria meningitidis e um componente inorgânico e uso da mesma

Info

Publication number
BRPI0107679B8
BRPI0107679B8 BRPI0107679A BRPI0107679A BRPI0107679B8 BR PI0107679 B8 BRPI0107679 B8 BR PI0107679B8 BR PI0107679 A BRPI0107679 A BR PI0107679A BR PI0107679 A BRPI0107679 A BR PI0107679A BR PI0107679 B8 BRPI0107679 B8 BR PI0107679B8
Authority
BR
Brazil
Prior art keywords
outer membrane
composition
neisseria meningitidis
serum group
membrane vesicles
Prior art date
Application number
BRPI0107679A
Other languages
English (en)
Inventor
Pizza Mariagrazia
Giuliani Marzia
Rappuoli Rino
Original Assignee
Chiron Spa
Chiron Srl
Gsk Vaccines S R L
Novartis Vaccines And Diagnostics S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0001067A external-priority patent/GB0001067D0/en
Priority claimed from GBGB0005699.4A external-priority patent/GB0005699D0/en
Application filed by Chiron Spa, Chiron Srl, Gsk Vaccines S R L, Novartis Vaccines And Diagnostics S R L filed Critical Chiron Spa
Publication of BRPI0107679B1 publication Critical patent/BRPI0107679B1/pt
Publication of BRPI0107679B8 publication Critical patent/BRPI0107679B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

"vacina de vesícula de membrana externa (omv) compreendendo proteínas de membrana externa do grupo sérico b de neisseria meningitidis". uma composição compreendendo (a) vesículas de membrana externa (omvs) do grupo sérico b de neisseria meningitidis e (b) um componente imunogênico selecionado ou dentre outras proteínas de neisseria ou fragmentos imunogênicos seus. o componente (b) inclui, de preferência, uma proteína proveniente de uma cepa nmb diferente daquela da qual derivam os omv do componente (a). os omvs são, de preferência, obtidos por extração de desoxicolato. opcionalmente, a composição pode também compreender um antígeno protetor contra outros patógenos.
BRPI0107679A 2000-01-17 2001-01-17 composição compreendendo vesículas de membrana externa do grupo sérico b de neisseria meningitidis e um componente inorgânico e uso da mesma BRPI0107679B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0001067.8 2000-01-17
GB0001067A GB0001067D0 (en) 2000-01-17 2000-01-17 Supplemented norwegian vaccine
GBGB0005699.4A GB0005699D0 (en) 2000-03-09 2000-03-09 Supplemented OMV vaccines
GB0005699.4 2000-03-09
PCT/IB2001/000166 WO2001052885A1 (en) 2000-01-17 2001-01-17 Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins

Publications (2)

Publication Number Publication Date
BRPI0107679B1 BRPI0107679B1 (pt) 2018-03-13
BRPI0107679B8 true BRPI0107679B8 (pt) 2021-05-25

Family

ID=26243421

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0107679A BRPI0107679B8 (pt) 2000-01-17 2001-01-17 composição compreendendo vesículas de membrana externa do grupo sérico b de neisseria meningitidis e um componente inorgânico e uso da mesma
BR0107679-5A BR0107679A (pt) 2000-01-17 2001-01-17 Vacina de vesìcula de membrana externa (omv) compreendendo proteìnas de membrana externa do grupo sérico b de neisseria meningitidis

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR0107679-5A BR0107679A (pt) 2000-01-17 2001-01-17 Vacina de vesìcula de membrana externa (omv) compreendendo proteìnas de membrana externa do grupo sérico b de neisseria meningitidis

Country Status (17)

Country Link
US (4) US8273360B2 (pt)
EP (6) EP1248647B1 (pt)
JP (6) JP2003520248A (pt)
CN (2) CN1416352B (pt)
AT (1) ATE476988T1 (pt)
AU (2) AU784518B2 (pt)
BR (2) BRPI0107679B8 (pt)
CA (2) CA2397508C (pt)
CY (3) CY1111056T1 (pt)
DE (1) DE60142772D1 (pt)
DK (3) DK1248647T3 (pt)
ES (2) ES2588917T3 (pt)
MX (1) MXPA02006962A (pt)
NZ (1) NZ520466A (pt)
PT (3) PT2289545T (pt)
RU (1) RU2279889C2 (pt)
WO (1) WO2001052885A1 (pt)

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BRPI0107679B1 (pt) 2018-03-13
CY1111056T1 (el) 2015-06-11
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